Is the Temporomandibular Joints’ Reciprocal Clicking Related to the Morphology and Position of the Mandible, as Well as to the Sagittal Position of Lower Incisors?—A Case-Control Study

The number of patients diagnosed with temporomandibular joint (TMJ) internal derangements, who are seeking orthodontic treatment, is increasing. The aim of the study was to assess the relationship between the presence of TMJ reciprocal clicking and the morphology and position of the mandible, and position of lower incisors, examined on the lateral cephalograms. Fifty patients diagnosed with reciprocal clicking in at least one of the TMJs and 55 patients with no symptoms of TMJ dysfunction were included in the study. Cephalometric analysis was used for the assessment of: skeletal class, sagittal and vertical position of the mandible, angle of the mandible, inclination of the mandibular ramus and the mandibular corpus, as well as for the assessment of the position of the mandibular incisors. The statistical significance level was set at p = 0.05. There were no statistically significant differences between the examined groups regarding the sagittal and vertical position of the mandible, as well as regarding the sagittal position of the mandibular incisors. Presence of TMJ reciprocal clicking is not associated with the position and the morphology of the mandible, as well as with the sagittal position of the mandibular incisors. Patients with early stages of TMJ internal derangements do not present any significant changes in Cephalometrics. Patients diagnosed with TMJ internal derangements before orthodontic treatment require an interdisciplinary approach to the treatment, including physiotherapy.

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Effects of Presurgical Mandibular Incisor Decompensation on Long-Term Outcomes of Class III Surgical Orthodontic Treatment

Journal of Clinical Medicine ◽

10.3390/jcm10132870 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2870

Author(s):

Jung-Sub An ◽

Wonchae Jeong ◽

Liselotte Sonnesen ◽

Seung-Hak Baek ◽

Sug-Joon Ahn

Keyword(s):

Orthodontic Treatment ◽

Group Differences ◽

Class Iii ◽

Class Iii Malocclusion ◽

Long Term Outcomes ◽

Mandibular Incisor ◽

Skeletal Class ◽

Lateral Cephalograms ◽

Mandibular Incisors

This research aimed to evaluate the effects of presurgical mandibular incisor decompensation on long-term outcomes of Class III surgical orthodontic treatment. Thirty-five patients with skeletal Class III malocclusion who received conventional surgical orthodontic treatment were included. Mandibular incisor brackets with −6° of inclination were placed normally in 18 patients (NB group) and inversely in 17 patients (RB group). Between-group differences and relationships between incisal and skeletal variables were analyzed based on lateral cephalograms at pretreatment, presurgery, postsurgery, posttreatment, and retention. Mandibular incisors were more labially inclined in the RB group than in the NB group from presurgery to retention. No significant between-group differences were observed in presurgical and postsurgical skeletal relationships. The NB group exhibited a larger overjet with deficient interincisal contact at postsurgery than the RB group. Skeletal Class III relationship was also more severe in the NB group at retention. More lingually inclined mandibular incisors at presurgery and larger overjet at postsurgery were correlated with a more severe skeletal Class III relationship at retention. Thus, establishing appropriate postsurgical overjet by sufficient presurgical mandibular incisor decompensation may play a significant role in postsurgical stability of Class III surgical orthodontic treatment.

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Skeletal Class III Malocclusion with Lateral Open Bite and Facial Asymmetry Treated with Asymmetric Lower Molar Extraction and Lingual Appliance: A Case Report

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18105381 ◽

2021 ◽

Vol 18 (10) ◽

pp. 5381

Author(s):

Vo Truong Nhu Ngoc ◽

Nguyen Thi Thu Phuong ◽

Nguyen Viet Anh

Keyword(s):

Case Report ◽

Open Bite ◽

Class Iii ◽

Class Iii Malocclusion ◽

Skeletal Class ◽

Facial Esthetics ◽

Lingual Appliance ◽

Lower Incisors ◽

Mandibular Incisors ◽

Molar Extraction

A skeletal Class III malocclusion with open bite tendency is considered very difficult to treat orthodontically without surgery. This case report describes the lingual orthodontic treatment of an adult skeletal Class III patient with mandibular deviation to the left side, lateral open bite, unilateral posterior crossbite, zero overbite and negative overjet. The lower incisors were already retroclined to compensate with the skeletal discrepancy. The patient was treated by asymmetric molar extraction in the mandibular arch to retract the lower incisors and correct the dental midline, with the help of intermaxillary elastics. Lingual appliance was used with over-torqued lower anterior teeth’s brackets to control the torque of mandibular incisors. After a 30-month treatment, satisfactory smile and facial esthetics and good occlusion was achieved. A 12-month follow-up confirmed that the outcome was stable. Asymmetric molar extraction could be a viable option to retract mandibular incisors in Class III malocclusion with lower dental midline deviation.

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Association of ADRB1 gene polymorphism with dilated cardiomyopathy

European Heart Journal Acute Cardiovascular Care ◽

10.1093/ehjacc/zuab020.012 ◽

2021 ◽

Vol 10 (Supplement_1) ◽

Author(s):

A Chernova ◽

SY Nikulina ◽

OO Kuznecova

Keyword(s):

Statistical Significance ◽

Rare Allele ◽

Public Institution ◽

Control Group ◽

Significance Level ◽

Funding Sources ◽

Idiopathic Cardiomyopathy ◽

Homozygous Genotype ◽

Number Of Patients ◽

Medical University

Abstract Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University Aim. To evaluate the Association of rs1801252 polymorphism of the ADRB1 gene with dilated idiopathic cardiomyopathy (DCMP) and myocardial dilation of ischemic origin (DMI). Subjects and methods. The study included patients with ICMP and MD IG in the number of 221 people. The average age of the subjects was in the range of 55.30 ± 9.69 years. We divided the patients into 2 groups: the first – patients diagnosed with idiopathic dilatation cardiomyopathy and the second-patients with myocardial dilatation of ichemic origin. The number of patients in the first group was 111, including 99 men (89.2%) and 12 women (10.8%). The average age of patients in this group is 51.73 ± 9.74 years, in men 51.00 ± 8.96 years, in women 57.75 ± 3.71 years. The second group included patients with myocardial dilatation of ischemic origin. Their number is 110 people, including 100 men (91.5%) and 10 women (8.5%). The average age of respondents is 58.68 ± 8.38 years, for men 58.29 ± 8.46 years, for women 62.90 ± 6.29 years. The control group included patients who had no manifestations of cardiovascular diseases. Their number is 121 people (average age 53.6 ± 4.8 years). The patients underwent laboratory and instrumental studies, as well as molecular and genetic studies of the A145G polymorphism of the ADRB1 gene (rs1801252 ). All patients underwent coronary angiography. Based on the anamnesis data and instrumental studies, those patients who could be said to have no risk factors for the development of dilatation of the heart cavities were identified in the first group. And those patients who were reliably diagnosed with CHD were in the second group, that is, dilatation of the heart cavities is due to a previous myocardial infarction, existing angina pectoris. Results. In the group with DCMP 70.3% of patients were carriers of the common homozygous A145A genotype, the heterozygous A145G genotype-27.0%, and the rare homozygous G145G genotype-2.7%. In the control group 71.9% of patients were identified as carriers of a homozygous genotype by a common allele, and 25.3% were carriers heterozygous genotype, and homozygous genotype for a rare allele – 2.7%. Statistical analysis showed no achievement of statistical significance level across any of the genotypes. In the group with DM IG, there was no association with the rs1801252 polymorphism of the ADRB1 gene. Conclusion. A statistically significant association of rs1801252 of the ADRB1 gene with DCMP was not found. The association of DM IG c rs1801252 could not be confirmed.

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LO046: Factors associated with hospital admission following asthma exacerbations: a systematic review

CJEM ◽

10.1017/cem.2016.83 ◽

2016 ◽

Vol 18 (S1) ◽

pp. S46-S46 ◽

Cited By ~ 1

Author(s):

B.H. Rowe ◽

N. Arrotta ◽

J. Hill ◽

E. Dennett ◽

M. Harries

Keyword(s):

Hospital Admissions ◽

Data Extraction ◽

Statistical Significance ◽

Grey Literature ◽

Included Study ◽

Significance Level ◽

Factors Associated ◽

Admission Rates ◽

Literature Searches ◽

Number Of Patients

Introduction: Patients with asthma frequently present to the emergency department (ED) with exacerbations; however, a select number of patients require admission to hospital. The objective of this study was to summarize the evidence regarding asthma-related hospital admissions and factors associated with these admissions following ED presentation. Methods: Comprehensive literature searches were conducted in seven electronic databases (database inception to 2015); manual and grey literature searches were also performed. Studies reporting disposition for adults after ED presentation were included. Study quality was assessed using the Newcastle-Ottawa Scale (NOS); standardized data-collection forms were used for data extraction. Admission proportions and factors associated with admission at a statistical significance level (p<0.05) were reported. Results: Out of an initial 5865 identified articles, 37 articles met full inclusion criteria. Admission proportions were reported in 25/37 studies, ranged from 1% to 37%, and collectively demonstrated a decline of ~9% in admissions between 1993 and 2012. Studies including a >50% Caucasian ethnicity were found to have a median admission proportion of 13% (interquartile range [IQR]= 7, 20) versus studies with >50% non-Caucasian ethnicity at 22% (IQR=20, 28). Age, female sex, and previous hospitalizations for asthma exacerbation were the most individually identifiable factors associated with admission. Presenting features and medication profile were the most frequent domains associated with admission. Conclusion: Admission rates have decreased approximately 9% in a nearly 20-year span and seem to be higher in studies involving mostly non-Caucasian ethnic groups. Demographic factors, markers of severity obtained by history or at ED presentation, and medication profile could be assessed by ED clinicians to effectively discern patients at high risk for admission.

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A comparison of treatment results of adult deep-bite cases treated with lingual and labial fixed appliances

The Angle Orthodontist ◽

10.2319/011021-29.1 ◽

2021 ◽

Author(s):

Hande Pamukçu ◽

Ömür Polat Özsoy

Keyword(s):

Orthodontic Treatment ◽

Inclusion Criteria ◽

Treatment Results ◽

Lower Incisor ◽

Deep Bite ◽

Mandibular Plane ◽

Number Of Patients ◽

Significant Difference ◽

Fixed Appliances ◽

Lower Incisors

ABSTRACT Objectives To compare the cephalometric treatment results of adult deep-bite cases after labial and lingual fixed orthodontic treatment. Materials and Methods A total of 102 patients underwent lingual orthodontic treatment and complete records were evaluated. The following inclusion criteria were used: patients who had Angle Class I or mild Class II malocclusion; comprehensive orthodontic treatment that did not include intrusion mechanics or any extractions; patients with an initial overbite of more than 3.7 mm. Thirteen patients met the inclusion criteria. These cases were matched with the same number of patients according to age with a labial orthodontic treatment group. Pre- and post-treatment cephalometric radiographs were evaluated. Independent t test or Fisher exact tests were performed to assess the differences between the groups. Results Proclination of the upper incisors was higher in the labial group. Incisor mandibular plane angle (IMPA) showed an increase of 1.2° in the lingual group and 9.7° in the labial group. Lower incisor edge was approximately in a stable sagittal position in the lingual group but significant lower incisor proclination was seen in the labial group. The lower incisors were intruded (-1 mm) in the lingual group but lower incisors were minimally extruded (0.3 mm) in the labial group. No significant difference was found in the movements of upper and lower molars for both groups. Conclusions The nature of lower incisor movement involved less protrusion in lingual orthodontics than the labial treatment. Lingual orthodontic treatment is a better option in adult cases where intrusion of lower incisors without labial tipping is desired.

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Cervical Posture and Skeletal Malocclusions – Is there a Link?

Journal of College of Medical Sciences-Nepal ◽

10.3126/jcmsn.v15i1.20509 ◽

2019 ◽

Vol 15 (1) ◽

pp. 5-9

Author(s):

Sanam Tauheed ◽

Attiya Shaikh ◽

Mubassar Fida

Keyword(s):

Statistical Significance ◽

Class I ◽

Class Iii ◽

Weak Correlation ◽

Pearson’S Correlation ◽

Significance Level ◽

Skeletal Class ◽

Pearson's Correlation ◽

One Way Anova ◽

Cervical Posture

Background: The present study was conducted in order to determine cervical posture in different skeletal sagittal malocclusions as well as to assess whether a correlation existed between cervical posture and skeletal relationships. Methods: Cervical curvature and inclination of 63 subjects was assessed using their lateral cephalometric radiographs. Cervical inclination was assessed using the cervicohorizontal postural variables namely OPT/HOR and CVT/HOR whereas cervical curvature was determined by measuring the angle OPT/CVT. Sagittally, the subjects were also categorized into skeletal Class I, II and III based on the angle ANB. One way ANOVA was used for the comparison of cervical posture in different skeletal sagittal malocclusions. Pearson’s correlation was used to evaluate the correlation of cervical posture with different skeletal sagittal jaw relations. Statistical significance level was set at p≤0.05. Results: Statistically significant differences were found between the different skeletal malocclusions for the cervical curvature angle OPT/CVT (p=0.025). A weak correlation of cervical curvature angle OPT/CVT (r=0.305, p=0.016) with sagittal malocclusion was found. Conclusions: Skeletal sagittal malocclusions differ in their cervical postures, especially cervical curvature. Skeletal Class III subjects have significantly straighter cervical columns than skeletal Class I subjects. Cervical curvature is correlated with sagittal jaw relations. Keywords: cervical curvature; cervical posture; skeletal sagittal malocclusions .

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Camouflage treatment of skeletal Class III malocclusion with multiloop edgewise arch wire and modified Class III elastics by maxillary mini-implant anchorage

The Angle Orthodontist ◽

10.2319/091312-730.1 ◽

2013 ◽

Vol 83 (4) ◽

pp. 630-640 ◽

Cited By ~ 21

Author(s):

Shushu He ◽

Jinhui Gao ◽

Peter Wamalwa ◽

Yunji Wang ◽

Shujuan Zou ◽

...

Keyword(s):

Principal Component ◽

Open Bite ◽

Control Group ◽

Vertical Position ◽

Class Iii ◽

Class Iii Malocclusion ◽

Skeletal Class ◽

Mini Implants ◽

Experimental Group ◽

Lower Incisors

ABSTRACT Objective: To evaluate the effect of the multiloop edgewise arch wire (MEAW) technique with maxillary mini-implants in the camouflage treatment of skeletal Class III malocclusion. Materials and Methods: Twenty patients were treated with the MEAW technique and modified Class III elastics from the maxillary mini-implants. Twenty-four patients were treated with MEAW and long Class III elastics from the upper second molars as control. Lateral cephalometric radiographs were obtained and analyzed before and after treatment, and 1 year after retention. Results: Satisfactory occlusion was established in both groups. Through principal component analysis, it could be concluded the anterior-posterior dental position, skeletal sagittal and vertical position, and upper molar vertical position changed within groups and between groups; vertical lower teeth position and Wits distance changed in the experimental group and between groups. In the experimental group, the lower incisors tipped lingually 2.7 mm and extruded 2.4 mm. The lingual inclination of the lower incisors increased 3.5°. The mandibular first molars tipped distally 9.1° and intruded 0.4 mm. Their cusps moved 3.4 mm distally. In the control group, the upper incisors proclined 3°, and the upper first molar extruded 2 mm. SN-MP increased 1.6° and S-Go/N-ME decreased 1. Conclusions: The MEAW technique combined with modified Class III elastics by maxillary mini-implants can effectively tip the mandibular molars distally without any extrusion and tip the lower incisors lingually with extrusion to camouflage skeletal Class III malocclusions. Clockwise rotation of the mandible and further proclination of upper incisors can be avoided. The MEAW technique and modified Class III elastics provided an appropriate treatment strategy especially for patients with high angle and open bite tendency.

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Mode of correction is related to treatment timing in Class II patients treated with the mandibular advancement locking unit (MALU) appliance

The Angle Orthodontist ◽

10.2319/071316-549.1 ◽

2017 ◽

Vol 87 (3) ◽

pp. 363-370

Author(s):

Muhsin Candir ◽

Heidi Kerosuo

Keyword(s):

Group Treatment ◽

Treatment Initiation ◽

Class Ii ◽

Mandibular Advancement ◽

Skeletal Maturation ◽

Total Change ◽

Skeletal Class ◽

Skeletal Class Ii ◽

Lateral Cephalograms ◽

Mandibular Incisors

ABSTRACT Objective: To investigate the proportion of skeletal/dentoalveolar components for correction of Class II malocclusion in relation to the pubertal growth peak (PGP) among patients treated with the mandibular advancement locking unit (MALU) appliance. Materials and Methods: We conducted a retrospective study of 27 orthodontic patients (age range: 12–18 years; mean age 14.9 years) with skeletal Class II Division 1 malocclusion who were treated with the MALU appliance until they reached Class I occlusion with overjet and overbite within normal range. Pretreatment (T1) and posttreatment (T2) lateral cephalograms were analyzed using standard cephalometrics and sagittal occlusion analysis to assess changes in the dentoalveolar and skeletal complex. The cervical vertebral maturation (CVM) method was used to determine participants' skeletal maturation in T1 cephalograms. Based on this maturation, participants were divided into two groups: the peak group (treatment initiation before or during PGP [peak group, n=15]) or the postpeak group (treatment initiation after the PGP [n = 12]). Results: No significant differences between groups were found at T1 for most of the skeletal and dental parameters investigated. At T2, the mean ANB angle and proclination of the mandibular incisors were significantly smaller in the peak group than in the postpeak group. In the peak group, skeletal correction comprised 54% and dental correction 46% of the total change at T2, while in the postpeak group the corresponding figures were 24% and 76%, respectively. Conclusions: Treatment initiated before or during PGP seems to result in a more favorable SNA/SNB relationship and less tipping of the mandibular incisors than when treatment is initiated after PGP.

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Apical root displacement is a critical risk factor for apical root resorption after orthodontic treatment

The Angle Orthodontist ◽

10.2319/111417-777.1 ◽

2018 ◽

Vol 88 (6) ◽

pp. 740-747 ◽

Cited By ~ 4

Author(s):

Kyoung-Won Kim ◽

Sung-Jin Kim ◽

Ji-Yeon Lee ◽

Yoon-Jeong Choi ◽

Chooryung J. Chung ◽

...

Keyword(s):

Risk Factors ◽

Orthodontic Treatment ◽

Root Resorption ◽

Critical Factor ◽

Mixed Effects ◽

Mixed Effects Model ◽

Linear Mixed Effects ◽

Apical Root Resorption ◽

Lateral Cephalograms ◽

Mandibular Incisors

ABSTRACT Objectives: To identify risk factors for apical root resorption (ARR) of maxillary and mandibular incisors using mathematical quantification of apical root displacement (ARD) and multiple linear mixed-effects modeling. Materials and Methods: Periapical radiographs of maxillary and mandibular incisors and lateral cephalograms of 135 adults were taken before and after orthodontic treatment. ARR was measured on the periapical radiographs, and movement of central incisors was evaluated on the superimposed pre- and posttreatment lateral cephalograms. ARD was mathematically calculated from pretreatment tooth length, inclination change, and movement of the incisal edge. Linear mixed-effects model analysis was performed to identify risk factors for ARR, and standardized coefficients (SCs) were calculated to investigate the relative contribution of the risk factors to ARR. Results: Vertical ARD showed the highest SCs for both maxillary and mandibular incisors. Horizontal ARD showed the second highest SC for mandibular incisors but was not significantly correlated with the ARR of maxillary incisors. When horizontal and vertical ARDs were included in the mixed-effects model, the use of self-ligating brackets was significantly correlated with increased ARR of mandibular incisors. Conclusions: ARD is a critical factor for ARR after orthodontic treatment. Careful monitoring of ARR is recommended for patients requiring significant ARD of incisors.

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Long-term evaluation of lower incisors gingival recessions after orthodontic treatment

European Journal of Orthodontics ◽

10.1093/ejo/cjy086 ◽

2019 ◽

Vol 41 (6) ◽

pp. 559-564 ◽

Cited By ~ 7

Author(s):

Fabienne Pernet ◽

Cristina Vento ◽

Nikolaos Pandis ◽

Stavros Kiliaridis

Keyword(s):

Orthodontic Treatment ◽

Alveolar Bone ◽

Facial Morphology ◽

Lower Incisor ◽

Term Retention ◽

Lateral Cephalograms ◽

Skeletal Pattern ◽

Long Term Retention ◽

Lower Incisors

Summary Aim The development of gingival recessions has been associated with orthodontic treatment; however, a clear etiology is still unknown. The aim of the present study was to further clarify potential association between the development of labial and lingual recessions and inclination of the lower incisors during orthodontic treatment, vertical facial morphology, width of the alveolar bone process, height and width of their symphysis after orthodontic treatment and at long-term retention. Methods On dental casts and good quality lateral cephalograms of 126 orthodontically treated patients, relevant measurements were performed and gingival recessions were assessed and recorded before, immediately after treatment and at long-term retention. Results Taking into account the whole sample at three different occasions, on the buccal side, the lateral incisors have significantly less recessions than the central incisor. On the lingual side, tooth 32 presented with lower risk of recession compared to all other three incisors. No association was found between the width of the alveolar bone process at the apex (Wapex), at the level of the crest (Wcrest) and at mid of the root (Wmid), the width (D), the vertical skeletal pattern (AnsPns-Go’Me) and the onset of buccal or lingual recessions. Development of new recessions was clearly associated with males and with increasing age. The symphysis height (Me-Wcrest) was statistically related with the onset of lingual recessions on 32 and 42. The ratio between the symphysis height and the width at the crest level demonstrated a statistically significant association with the presence of buccal and lingual recessions. Excessive proclination (≥10°) of the lower incisors demonstrated an association with the onset of recessions in 25 per cent of the cases. Conclusion Based on the sample of this study, there is some evidence that increased symphysis height (Me-Wcrest), and ratio between the symphysis height and the width at the crest level as well as big change of lower incisor inclination during treatment are associated with the development of recessions.

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