scholarly journals Higher 90-Day Mortality after Surgery for Hip Fractures in Patients with COVID-19: A Case–Control Study from a Single Center in Italy

2021 ◽  
Vol 18 (10) ◽  
pp. 5205
Author(s):  
Alberto Grassi ◽  
Luca Andriolo ◽  
Davide Golinelli ◽  
Dario Tedesco ◽  
Simona Rosa ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Control Groups ◽  
Perioperative Mortality ◽  
Risk Of Mortality ◽  
Matched Case ◽  
And Control ◽  
Matched Case Control Study ◽  
Control Study

The mortality of hip fracture (HF) patients is increased by concomitant COVID-19; however, evidence is limited to only short follow-up. A retrospective matched case–control study was designed with the aim to report the 90-day mortality and determine the hazard ratio (HR) of concomitant HF and COVID-19 infection. Cases were patients hospitalized for HF and diagnosed with COVID-19. Controls were patients hospitalized for HF not meeting the criteria for COVID-19 diagnosis and were individually matched with each case through a case–control (1:3) matching algorithm. A total of 89 HF patients were treated during the study period, and 14 of them were diagnosed as COVID-19 positive (overall 15.7%). Patients’ demographic, clinical, and surgical characteristics were similar between case and control groups. At 90 days after surgery, 5 deaths were registered among the 14 COVID-19 cases (35.7%) and 4 among the 42 HF controls (9.5%). COVID-19-positive cases had a higher risk of mortality at 30 days (HR = 4.51; p = 0.0490) and 90 days (HR = 4.50; p = 0.025) with respect to controls. Patients with concomitant HF and COVID-19 exhibit high perioperative mortality, which reaches a plateau of nearly 30–35% after 30 to 45 days and is stable up to 90 days. The mortality risk is more than four-fold higher in patients with COVID-19.

scholarly journals Longer Time to Reach Excellent Response to Treatment in Familial Versus Sporadic Non-medullary Thyroid Cancer (NMTC): A Matched Case-Control Study

2021 ◽  
Vol 19 (2) ◽  
Author(s):  
Susan Shafiei ◽  
Mehrdokht Sadrolodabaei ◽  
Atena Aghaei ◽  
Narjess Ayati ◽  
Samira Zare Namdar ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Response To Treatment ◽  
Control Groups ◽  
Excellent Response ◽  
Significant Difference ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

Background: Familial NMTCs are supposed to be more aggressive and require more frequent treatment compared to non-familial thyroid cancer. Objectives: This matched case-control study aimed to compare the response to treatment between the matched case-control groups of familial and sporadic NMTC. Methods: This is a retrospective study in patients with familial NMTC (at least one other first-degree relative involved) who were treated with surgery, followed by radio-iodine therapy (RIT) without consideration of its familial origin. Response to treatment was compared between familial NMTC and age, sex, and TNM stage-matched non-familial NMTC (control group). Response to treatment was assessed one and two years after RIT, and time to excellent response was identified. Results: Out of 2,944 NMTC patients, 81 (2.75%) patients had familial NMTC. We compared 66 patients with familial NMTC and 66 sporadic NMTC patients. There was no significant difference in first thyroglobulin, initial and accumulative iodine dose, and additional treatments (additional surgery and radiotherapy) between patients and controls. Although no significant difference was noted in one and two years’ responses to treatment between the case and control groups, familial NMTC patients required more time to achieve excellent response (26.7 ± 24.9 versus 15.9 ± 9.0 months, P = 0.01). No significant difference was noted between familial NMTC patients with two or more than two involved relatives. Conclusions: Our study showed that if patients with familial NMTCs were treated in the same way as non-familial patients, the time to excellent response would be significantly longer, even when they have only one other involved relative.

Exploring the Effects of Telemedicine on Bariatric Surgery Follow-up: a Matched Case Control Study

2019 ◽  
Vol 29 (8) ◽  
pp. 2704-2706 ◽  
Author(s):  
Chen D. Wang ◽  
Thiyake Rajaratnam ◽  
Benjamin Stall ◽  
Raed Hawa ◽  
Sanjeev Sockalingam
Keyword(s):  
Bariatric Surgery ◽  
Case Control Study ◽  
Case Control ◽  
Matched Case ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Evaluation of serum calcium differences in hypertensive crises and control patients: A randomly matched case‐control study

2021 ◽  
Author(s):  
IfeanyiChukwu O. Onor ◽  
Rose M. Duchane ◽  
Casey J. Payne ◽  
Hannah Naquin Lambert ◽  
DeMaurian M. Mitchner ◽  
...  
Keyword(s):  
Serum Calcium ◽  
Case Control Study ◽  
Case Control ◽  
Matched Case ◽  
Hypertensive Crises ◽  
And Control ◽  
Matched Case Control Study ◽  
Control Study

scholarly journals Determinants of first line antiretroviral therapy treatment failure among adult patients on ART at central Ethiopia: un-matched case control study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Diriba Mulisa ◽  
Mulugeta Tesfa ◽  
Getachew Mullu Kassa ◽  
Tadesse Tolossa
Keyword(s):  
Logistic Regression ◽  
Treatment Failure ◽  
Case Control Study ◽  
Case Control ◽  
First Line ◽  
Matched Case ◽  
Lost To Follow Up ◽  
Matched Case Control Study ◽  
Control Study

Abstract Background In 2018 in Ethiopia, magnitude of human immunodeficiency virus Acquired Immunodeficiency Syndrome treatment failure was 15.9% and currently the number of patient receiving second line antiretroviral therapy (ART) is more increasing than those taking first line ART. Little is known about the predictors of treatment failure in the study area. Therefore; more factors that can be risk for first line ART failure have to identified to make the patients stay on first line ART for long times. Consequently, the aim of this study was to identify determinants of first line ART treatment failure among patients on ART at St. Luke referral hospital and Tulubolo General Hospital, 2019. Methods A 1:2 un-matched case-control study was conducted among adult patients on active follow up. One new group variables was formed as group 1 for cases and group 0 for controls and then data was entered in to Epi data version 3 and exported to STATA SE version 14 for analysis. From binary logistic regression variables with p value ≤0.25 were a candidate for multiple logistic regression. At the end variables with a p-value ≤0.05 were considered as statistically significant. Result A total of 350 (117 cases and 233 controls) patients were participated in the study. Starting ART after 2 years of being confirmed HIV positive (AOR = 3.82 95% CI 1.37,10.6), nevirapine (NVP) based initial ART (AOR = 2.77,95%CI 1.22,6.28) having history of lost to follow up (AOR 3.66,95%CI 1.44,9.27) and base line opportunistic infection (AOR = 1.97,95%CI 1.06,3.63), staying on first line ART for greater than 5 years (AOR = 3.42,95%CI 1.63,7.19) and CD4 less than100cell/ul (AOR = 2.72,95%CI 1.46,5.07) were independent determinants of first line ART treatment failure. Conclusion Lost to follow up, staying on first line ART for greater than 5 years, presence of opportunistic infections, NVP based NNRT, late initiation of ART are determinant factors for first line ART treatment failure. The concerned bodies have to focus and act on those identified factors to maintain the patient on first line ART.

scholarly journals Evaluation of serum magnesium differences in hypertensive crises and control patients: A randomly matched case‐control study

2021 ◽  
Author(s):  
IfeanyiChukwu O. Onor ◽  
Emily K. Johnston ◽  
Nicole G. Little ◽  
Lashira M. Hill ◽  
Oluwabunmi E. Lawal ◽  
...  
Keyword(s):  
Case Control Study ◽  
Serum Magnesium ◽  
Case Control ◽  
Matched Case ◽  
Hypertensive Crises ◽  
And Control ◽  
Matched Case Control Study ◽  
Control Study
Sign in / Sign up

Export Citation Format

Share Document