scholarly journals Assessing Performance of the Veterans Affairs Women Cardiovascular Risk Model in Predicting a Short-Term Risk of Cardiovascular Disease Incidence Using United States Veterans Affairs COVID-19 Shared Data

Author(s):  
Haekyung Jeon-Slaughter ◽  
Xiaofei Chen ◽  
Bala Ramanan ◽  
Shirling Tsai

The current study assessed performance of the new Veterans Affairs (VA) women cardiovascular disease (CVD) risk score in predicting women veterans’ 60-day CVD event risk using VA COVID-19 shared cohort data. The study data included 17,264 women veterans—9658 White, 6088 African American, and 1518 Hispanic women veterans—ever treated at US VA hospitals and clinics between 24 February and 25 November 2020. The VA women CVD risk score discriminated patients with CVD events at 60 days from those without CVD events with accuracy (area under the curve) of 78%, 50%, and 83% for White, African American, and Hispanic women veterans, respectively. The VA women CVD risk score itself showed good accuracy in predicting CVD events at 60 days for White and Hispanic women veterans, while it performed poorly for African American women veterans. The future studies are needed to identify non-traditional factors and biomarkers associated with increased CVD risk specific to African American women and incorporate them to the CVD risk assessment.

2011 ◽  
Vol 14 (2) ◽  
pp. 171-179 ◽  
Author(s):  
Queen Henry-Okafor ◽  
Patricia A. Cowan ◽  
Mona N. Wicks ◽  
Muriel Rice ◽  
Donna S. Husch ◽  
...  

Obesity is a growing health care concern with implications for cardiovascular disease (CVD). Obesity and CVD morbidity and mortality are highly prevalent among African American women. This pilot study examined the association between obesity and the traditional and emerging CVD risk factors in a sample of African American women. Participants comprised 48 women (27 obese, 21 normal weight) aged 18–45. with no known history of CVD. The women completed demographic and 7-day physical activity recall questionnaires. Height and weight were used to determine body mass index (BMI). Hypertension risk was assessed using the average of two resting blood pressure (BP) measurements. Lipid profile, blood glucose, fibrinogen, high-sensitivity C-reactive protein (hs-CRP), plasminogen activator inhibitor-1 (PAI-1), soluble intercellular adhesion molecule-1 (sICAM-1), and E-selectin (eSel) levels were assessed using fasting blood samples. Laboratory findings were interpreted using the American Diabetes Association (ADA) and Adult Treatment Panel (ATP) III reference guidelines as well as manufacturers’ reference ranges for the novel CVD risk factors. The most common traditional risk factors were physical inactivity (72.9%), positive family history of CVD (58.3%), and obesity (56.3%). Obese individuals had elevated systolic BP ( p = .0002), diastolic BP ( p = .0007) and HDL-cholesterol ( p = .01), triglyceride ( p = .02), hs-CRP ( p = .002), and fibrinogen ( p = .01), when compared with normal-weight women. The findings suggest an association between obesity and higher prevalence of both traditional and emerging CVD risk factors in young African American women.


2012 ◽  
Vol 44 (3) ◽  
pp. 525-533 ◽  
Author(s):  
LYNDSEY M. HORNBUCKLE ◽  
PEI-YANG LIU ◽  
JASMINKA Z. ILICH ◽  
JEONG-SU KIM ◽  
BAHRAM H. ARJMANDI ◽  
...  

2011 ◽  
pp. 1614-1620
Author(s):  
Jing Chong

HIV (human immunodeficiency virus) and AIDS (acquired immunodeficiency syndrome) represent a growing and significant health threat to women worldwide. According to the United Nations (UNAIDS/WHO, 2004), women now make up nearly half of all people living with HIV worldwide. In the United States, although males still accounted for 73% of all AIDS cases diagnosed in 2003, there is a marked increase in HIV and AIDS diagnoses among females. The estimated number of AIDS cases increased 15% among females and 1% among males from 1999 through 2003 (Centers for Disease Control and Prevention, 2003). Looking closer at HIV and AIDS infections among women in the United States, Anderson and Smith (2004) report that HIV infection was the leading cause of death in 2001 for African-American women aged 25 to 34 years, and was among the four leading causes of death for African-American women aged 20 to 24 and 35 to 44 years, as well as Hispanic women aged 35 to 44 years. The rate of AIDS diagnoses for African-American women (50.2 out of 100,000 women) was approximately 25 times the rate for white women (2 out of 100,000) and 4 times the rate for Hispanic women (12.4 out of 100,000; Centers for Disease Control and Prevention). African-American and Hispanic women together represented about 25% of all U.S. women (U.S. Census Bureau, 2000), yet they account for 83% of AIDS diagnoses reported in 2003 (Centers for Disease Control and Prevention). Women’s vulnerability to HIV and AIDS may be attributed to gender inequalities in socioeconomic status, stereotypes of AIDS as a gay-male disease, and cultural ideology around sexual practices such as abstinence, monogamy, and condom use. Because of cultural mores and socioeconomic disadvantages, women may consequently have less access to prevention and care resources. Information is perhaps the most important HIV and AIDS resource for women, and the Internet provides a useful platform for disseminating information to a large cross-section of women. With the flourishing use of e-health resources and the growing number of public-access Internet sites, more and more people are using the Internet to obtain health-care information. Over two thirds of Americans (67%) are now online (Internet World Statistics, 2005). On a typical day, about 6 million Americans go online for medical advice. This exceeds the number of Americans who actually visit health professionals (Fox & Rainie, 2002). Studies also show that women are more likely to seek health information online than are men (Fox & Fallows, 2003; Fox & Rainie, 2000; Hern, Weitkamp, Hillard, Trigg, & Guard, 1998). HIV and AIDS patients are among the health-care consumers with chronic medical conditions who increasingly take the Internet as a major source of information (Kalichman, Weinhardt, Benotsch, & Cherry, 2002).


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Telisa Spikes ◽  
Raphiel Murden ◽  
Izraelle McKinnon ◽  
Miriam Van Dyke ◽  
Samantha Bromfield ◽  
...  

Title: Net Worth, Debt Stress, and Ambulatory Blood Pressure in African American Women Author Names: Telisa Spikes, RN, PHD, Raphiel Murden, MS, Izraelle McKinnon, MPH, Miriam Van Dyke, PhD, Samantha Bromfield, PhD, Renee Moore, PhD, Bianca Booker, MA, Frederic Rahbari-Oskoui MD, Arshed Quyyumi, MD, Viola Vaccarino, MD, PhD, Tené T. Lewis, PhD Background: Low socioeconomic status (SES) is an established predictor of higher cardiovascular disease (CVD) incidence and mortality. Research suggests that neither higher education nor income have been consistently associated with lower CVD risk or outcomes in African Americans (AAs). Net worth and debt stress are two underexamined indices of SES that may be more important for CVD risk, especially in AAs, due to attenuated returns of traditional indicators of SES on health, and the high rates of debt in this group. Objective: To examine the associations of net worth and debt stress, independent of education and income, with ambulatory blood pressure (ABP) in AA women. Methods: Participants were AA women (n=422), mean age 37±4.2 years from various sociodemographic backgrounds recruited from a large metropolitan southeastern region. Net worth was measured using a single item (“Suppose you and others in your household were to sell all of your major possessions including your home, turn all of your investments and other assets into cash, and pay off all of your debts. Would you have something left over, break even, or be in debt?”) with three response categories, left over , break-even , and debt . Debt stress was measured using the four-item Debt Stress Index (e.g. “Overall, how often do you worry about the total amount you and your spouse/partner owe in overall debt?”). ABP was assessed over 48 hours. Multiple linear regression was used to evaluate associations between SES indicators and continuous ABP outcomes adjusting for age, education, income, BMI, BP meds, and depressive symptoms. Results: Overall, 48% of the cohort was categorized as having a positive (“left over”) net worth, while 30% and 22% were categorized as having a neutral (“break-even”), and negative (“debt”) net worth, respectively. Compared to the positive net worth group, negative net worth was associated with higher daytime (ß=5.2; CI: 2.44-8.05 ) and nighttime systolic blood pressure (SBP) (ß=5.3; CI: 2.59-8.06 ) in unadjusted analyses. Findings remained significant for both daytime (ß=4.3; CI:1.38-7.24 ) and nighttime (ß=4.1; CI:1.26-6.90 ) SBP in fully adjusted models. There were no significant unadjusted or fully-adjusted associations between debt stress and daytime, or nighttime SBP. Discussion: Negative net worth was associated with a 4.3 mm Hg higher daytime, and 4.1 mm Hg nighttime SBP independent of education and income. Future research is needed to determine the prospective impact of net worth on long-term CVD risk in AA women.


Hypertension ◽  
2019 ◽  
Vol 74 (Suppl_1) ◽  
Author(s):  
Srividya Kidambi ◽  
Priyanka Agarwal ◽  
Almira Yang ◽  
Thomas Chelius ◽  
David Mattson ◽  
...  

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