The Dose–Response Relationships of Different Dimensions of Physical Activity with Daily Physical Function and Cognitive Function in Chinese Adults with Hypertension: A Cross-Sectional Study

Objective: The purpose of this study was to explore the dose–response relationships of different dimensions of physical activity (intensity, time, frequency, capacity, and metabolic equivalent) with daily physical function (DPF) and cognitive function (CF) in Chinese adults with hypertension. Methods: The 6216 hypertensive patients included in this study were from the China Health and Retirement Longitudinal Study (CHARLS), which was conducted in 2015. Physical activity (PA) was divided into vigorous PA (VPA), moderate PA (MPA), and light PA (LPA). Linear regression models and binary logistic regression models were established to assess the associations with indicators. Results: Patients with VPA have a lower probability of impaired DPF; however, patients with VPA had lower CF scores. Patients with nearly all the aspects of MPA have lower rates of impaired DPF and higher CF scores (p < 0.05). Patients with LPA have a lower probability of impaired DPF and higher CF scores. In addition, patients with between 1800 and 2999 MET-minutes per week had the lowest rates of impaired DPF (OR = 0.10, 95% CI 0.02, 0.39) and the highest CF scores (β = 3.28, 95% CI 2.25, 4.31). Conclusions: This study found that patients with hypertension with moderate-intensity physical activity (nearly all aspects) and LPA had better DPF and CF. The best daily physical function and CF was with METs of 1800–2999 min per week. However, VPA should be recommended with caution in Chinese adults with hypertension.

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Dose–response effects of years of self-reported physical activity on old females’ motor and cognitive function

Brazilian Journal of Physical Therapy ◽

10.1016/j.bjpt.2018.06.002 ◽

2019 ◽

Vol 23 (1) ◽

pp. 48-55 ◽

Cited By ~ 1

Author(s):

Juliana Bayeux Dascal ◽

Lianne Maria Jantien Sanders ◽

Edson Gonsales da Cruz Filho ◽

Tibor Hortobágyi

Keyword(s):

Physical Activity ◽

Cognitive Function ◽

Dose Response ◽

Old Females

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Dose-response association between physical activity and clustering of modifiable cardiovascular risk factors among 26,093 Chinese adults

BMC Cardiovascular Disorders ◽

10.1186/s12872-020-01627-6 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Rui Shi ◽

Yamei Cai ◽

Rui Qin ◽

Yang Yan ◽

Dahai Yu

Keyword(s):

Physical Activity ◽

Risk Factors ◽

Cardiovascular Risk ◽

Cardiovascular Risk Factors ◽

Dose Response ◽

Chinese Adults

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Dose–Response Association Between Physical Activity and Cognitive Function in a National Sample of Older Adults

American Journal of Health Promotion ◽

10.1177/0890117116689732 ◽

2017 ◽

Vol 32 (3) ◽

pp. 554-560 ◽

Cited By ~ 9

Author(s):

Paul D. Loprinzi ◽

Meghan K. Edwards ◽

Elizabeth Crush ◽

Toshikazu Ikuta ◽

Alberto Del Arco

Keyword(s):

Physical Activity ◽

Older Adults ◽

Cognitive Function ◽

Dose Response ◽

Vigorous Physical Activity ◽

National Sample ◽

Self Report ◽

Favorable Effect ◽

Digit Symbol Substitution Test ◽

Metabolic Equivalent Of Task

Purpose: Previous research demonstrates a favorable effect of physical activity on cognitive function among older adults. The potential dose–response relationship between physical activity and cognitive function in this population is less understood, which was the purpose of this study. Setting: Data from the 1999 to 2002 National Health and Nutrition Examination Survey were employed. Participants: A total of 2157 older adults aged 60 to 85 years. Measures: Cognitive function was assessed from the Digit Symbol Substitution Test. Moderate-to-vigorous physical activity (MVPA), expressed as metabolic equivalent of task (MET)-min-month (MET-min-month = days × duration × MET level), was assessed via self-report, with 5 MVPA categories evaluated: (1) <2000 MVPA MET-min-month, (2) 2000 to 3999 MVPA MET-min-month, (3) 4000 to 5999 MVPA MET-min-month, (4) 6000 to 7999 MVPA MET-min-month, and (5) 8000+ MVPA MET-min-month. Analysis: Weighted multivariable linear regression. Results: An inverted U-shaped relationship was observed. Consistent across several adjusted models, those who engaged in 6000 to 7999 MVPA MET-min-month had the highest cognitive function score. Conclusion: The results suggest an optimal amount of physical activity to prevent the cognitive decline associated with aging.

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Dose-Response Relation Between Physical Activity and Cognitive Function: Guangzhou Biobank Cohort Study

Annals of Epidemiology ◽

10.1016/j.annepidem.2011.06.002 ◽

2011 ◽

Vol 21 (11) ◽

pp. 857-863 ◽

Cited By ~ 17

Author(s):

Lin Xu ◽

Chao Qiang Jiang ◽

Tai Hing Lam ◽

Wei Sen Zhang ◽

G. Neil Thomas ◽

...

Keyword(s):

Physical Activity ◽

Cohort Study ◽

Cognitive Function ◽

Dose Response

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Relationship Between Accelerometer-Determined Steps/Day and Other Accelerometer Outputs in U.S. Adults

Journal of Physical Activity and Health ◽

10.1123/jpah.8.3.410 ◽

2011 ◽

Vol 8 (3) ◽

pp. 410-419 ◽

Cited By ~ 18

Author(s):

Catrine Tudor-Locke ◽

William D. Johnson ◽

Peter T. Katzmarzyk

Keyword(s):

Physical Activity ◽

Regression Models ◽

Moderate Intensity ◽

Nutrition Examination Survey ◽

Sedentary Behaviors ◽

Linear Regression Models ◽

Wear Time ◽

Health And Nutrition ◽

Vigorous Intensity ◽

The Relationship

Background:The purpose of this study was to examine the relationship between 2005−2006 National Health and Nutrition Examination Survey (NHANES) accelerometer-determined steps/day and activity counts/day, and between steps/day and estimates of nonwear time (as an indicator of the unmonitored day) and time spent in sedentary behaviors as well as a range of physical activity intensities.Methods:Linear regression models were used to characterize the relationship between steps/day, activity counts/day, estimates of wear time, and intensity categories.Results:1781 males (mean age = 46.5 years) and 1963 females (mean age = 47.7 years) wore accelerometers 14.0 ± SEM0.06 hours/day. The relationship between steps/day and activity counts/day was positive and strong (R2 = .87). The relationship between steps/day and time spent in sedentary behaviors was inverse and moderate (R2 = .25). Stronger and positive relationships were apparent between steps/day and time in light (R2 = .69) and moderate (R2 = .63) intensity activities. There was no discernable relationship between steps/day and time spent in low or vigorous intensity activities or with wear time.Conclusions:Assessed by accelerometer, steps/day explains 87% of the variation in activity counts/day, 25% of the variation in time in sedentary behaviors, 69% of time in light intensity, and 63% of time in moderate intensity.

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Home-Based Exercise Prehabilitation During Preoperative Treatment for Pancreatic Cancer Is Associated With Improvement in Physical Function and Quality of Life

Integrative Cancer Therapies ◽

10.1177/1534735419894061 ◽

2019 ◽

Vol 18 ◽

pp. 153473541989406 ◽

Cited By ~ 8

Author(s):

An Ngo-Huang ◽

Nathan H. Parker ◽

Eduardo Bruera ◽

Rebecca E. Lee ◽

Richard Simpson ◽

...

Keyword(s):

Quality Of Life ◽

Physical Activity ◽

Pancreatic Cancer ◽

Aerobic Exercise ◽

Physical Function ◽

Pancreatic Adenocarcinoma ◽

Moderate Intensity ◽

Home Based

Purpose: To investigate relationships among physical activity, changes in physical function, and health-related quality of life (HRQOL) among patients with pancreatic adenocarcinoma enrolled in a home-based exercise prehabilitation program. Methods: Patients with resectable pancreatic adenocarcinoma receiving preoperative chemotherapy and/or chemoradiation were enrolled on this prospective, single-arm trial and were advised to perform ≥60 minutes each of moderate-intensity aerobic exercise and strengthening exercise weekly. Activity was measured via self-report and accelerometers, including moderate-to-vigorous physical activity (MVPA), light physical activity (LPA), and sedentary activity (SA). Physical function measures at baseline and restaging follow-up included 6-minute walk test (6MWT), 5 times sit-to-stand (5×STS), handgrip strength (HGS), 3-m walk for gait speed (GS), and the PROMIS Physical Function Short Form. HRQOL was measured via the FACT-Hep questionnaire. Results: Fifty participants with mean age 66 years (standard deviation = 8 years) were enrolled. The 6MWT, 5×STS, and GS significantly improved from baseline to restaging follow-up (P=.001, P=.049, and P=.009, respectively). Increases in self-reported aerobic exercise, weekly MVPA, and LPA were associated with improvement in 6MWT (β=.19, P=.048; β=.18, P=.03; and β=.08, P=.03, respectively) and self-reported physical functioning (β=.02, P=.03; β=.03, P=.005; and β=.01, P=.02, respectively). Increased weekly LPA was associated with increased HRQOL (β=.03, P=.02). Increased SA was associated with decreased HRQOL (β=-.02,P=.01). Conclusions: Patients with potentially resectable pancreatic cancer exhibit meaningful improvement in physical function with prehabilitation; physical activity was associated with improved physical function and HRQOL. These data highlight the importance of physical activity during treatment for pancreatic cancer.

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A healthy diet and physical activity are important to promote healthy ageing among older Chinese people

Journal of International Medical Research ◽

10.1177/0300060519882590 ◽

2019 ◽

Vol 47 (12) ◽

pp. 6061-6081 ◽

Cited By ~ 1

Author(s):

Zeyun Feng ◽

Jane Murray Cramm ◽

Anna Petra Nieboer

Keyword(s):

Physical Activity ◽

Depressive Symptoms ◽

Cognitive Function ◽

Health Outcomes ◽

Physical Function ◽

Chinese Population ◽

Healthy Diet ◽

World Health ◽

Diet And Physical Activity ◽

Older Chinese

Objective To examine the associations between multiple health behaviours and health outcomes among older Chinese adults. Methods Data from the World Health Organization’s Study on global AGEing and adult health Wave 1 (2007–2010), collected among the older Chinese population, were included in this study. Smoking, diet, and physical activity were analysed by linear regression for any associations with depressive symptoms, quality of life (QoL), cognitive function, and physical function. Results A total of 13 367 participants aged >49 years were included in the analyses. After controlling for key socioeconomic factors, healthy diet was significantly associated with higher QoL (β = 0.099) and better cognitive function (β = 0.023). Physical activity was significantly associated with fewer depressive symptoms (β = –0.020), higher QoL (β = 0.086), better cognitive function (β = 0.072), and better physical function (β = –0.155 [higher scores = poorer physical function]). No relationship was found between smoking and any health-related outcome included in this study. Conclusion This study demonstrates the importance of healthy diet and physical activity for health outcomes in the older Chinese population.

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Correlates Among Physical Activity, Physical Function, and Cognitive Function in Older Adults

Medicine & Science in Sports & Exercise ◽

10.1249/01.mss.0000517684.61217.7d ◽

2017 ◽

Vol 49 (5S) ◽

pp. 300

Author(s):

Victoria E. Warren ◽

Megan C. Rigot ◽

Kelsey D. Loss ◽

Colleen A. Osbun ◽

Kyle L. Timmerman

Keyword(s):

Physical Activity ◽

Older Adults ◽

Cognitive Function ◽

Physical Function

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212Dose-response association and interaction between physical activity and sedentary time on premature rupture of membranes

International Journal of Epidemiology ◽

10.1093/ije/dyab168.746 ◽

2021 ◽

Vol 50 (Supplement_1) ◽

Author(s):

Yongle Zhan ◽

Yu Jiang

Keyword(s):

Physical Activity ◽

Light Intensity ◽

Pregnant Women ◽

Dose Response ◽

Sedentary Time ◽

Moderate Intensity ◽

Response Relationship ◽

Premature Rupture Of Membranes ◽

Dose Response Relationship ◽

Premature Rupture

Abstract Background Premature rupture of membranes (PROM) is a common pregnancy complication with multifactorial etiology. However, associations between physical activity (PA) and PROM are still unclear. Therefore, this study aims to explore the dose-response relationship and interactions between PA frequency, sedentary time (ST) and PROM. Methods Data on 6848 pregnant women were obtained from the Chinese Pregnant Women Cohort Study. Participants were recruited from July 2017 to November 2018 and were followed up until delivery. The International Physical Activity Questionnaire-Short Form was used to assess the frequency of PA and ST. Logistic regression and restricted cubic spline (RCS) model were used for data analyses. Results Women with frequencies of over 4 days/week of moderate-intensity PA (OR:1.50, 95%CI:1.01∼2.23) and light-intensity PA (OR:1.19, 95%CI:1.04∼1.37) had higher risks of PROM respectively. The RCS model showed that the risk for PROM was significant with frequencies of over 2 days/week of vigorous-intensity PA, over 5 days/week of moderate-intensity PA or over 5 days/week of light-intensity PA (ORs with 95%CI >1). Interactions analyses showed that risks for PROM increased with frequencies of moderate-intensity and light-intensity PA both over 4 days/week (OR:1.80, 95%CI:1.17∼2.77), or with a frequency of light-intensity PA of over 4 days/week and ST of over 6 hours/day (OR:1.36, 95%CI:1.10∼1.69). Conclusions It is necessary to propose a suitable recommendation of frequency and intensity of PA, and identify and propose the corresponding intervention ways to reduce and prevent PROM occurrence during pregnancy. Key messages There is a dose-response relationship and interaction between PA and ST on PROM.

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