Dose-Response Relation Between Physical Activity and Cognitive Function: Guangzhou Biobank Cohort Study

2011 ◽  
Vol 21 (11) ◽  
pp. 857-863 ◽  
Author(s):  
Lin Xu ◽  
Chao Qiang Jiang ◽  
Tai Hing Lam ◽  
Wei Sen Zhang ◽  
G. Neil Thomas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Cognitive Function ◽  
Dose Response

scholarly journals The Dose–Response Relationships of Different Dimensions of Physical Activity with Daily Physical Function and Cognitive Function in Chinese Adults with Hypertension: A Cross-Sectional Study

2021 ◽  
Vol 18 (23) ◽  
pp. 12698
Author(s):  
Meng Ding ◽  
Ningxin Jia ◽  
Yanan Zhou ◽  
Bin Li
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Physical Function ◽  
Dose Response ◽  
Regression Models ◽  
Moderate Intensity ◽  
Lower Probability ◽  
Chinese Adults ◽  
Time Frequency ◽  
Different Dimensions

Objective: The purpose of this study was to explore the dose–response relationships of different dimensions of physical activity (intensity, time, frequency, capacity, and metabolic equivalent) with daily physical function (DPF) and cognitive function (CF) in Chinese adults with hypertension. Methods: The 6216 hypertensive patients included in this study were from the China Health and Retirement Longitudinal Study (CHARLS), which was conducted in 2015. Physical activity (PA) was divided into vigorous PA (VPA), moderate PA (MPA), and light PA (LPA). Linear regression models and binary logistic regression models were established to assess the associations with indicators. Results: Patients with VPA have a lower probability of impaired DPF; however, patients with VPA had lower CF scores. Patients with nearly all the aspects of MPA have lower rates of impaired DPF and higher CF scores (p < 0.05). Patients with LPA have a lower probability of impaired DPF and higher CF scores. In addition, patients with between 1800 and 2999 MET-minutes per week had the lowest rates of impaired DPF (OR = 0.10, 95% CI 0.02, 0.39) and the highest CF scores (β = 3.28, 95% CI 2.25, 4.31). Conclusions: This study found that patients with hypertension with moderate-intensity physical activity (nearly all aspects) and LPA had better DPF and CF. The best daily physical function and CF was with METs of 1800–2999 min per week. However, VPA should be recommended with caution in Chinese adults with hypertension.

scholarly journals Dose–response effects of years of self-reported physical activity on old females’ motor and cognitive function

2019 ◽  
Vol 23 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Juliana Bayeux Dascal ◽  
Lianne Maria Jantien Sanders ◽  
Edson Gonsales da Cruz Filho ◽  
Tibor Hortobágyi
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
Dose Response ◽  
Old Females

scholarly journals Effects of physical activity and sedentary behaviour on cardiometabolic risk factors and cognitive function in children: protocol for a cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e030322 ◽  
Author(s):  
Yajie Lv ◽  
Li Cai ◽  
Zhaohuan Gui ◽  
Xia Zeng ◽  
Minyi Tan ◽  
...  
Keyword(s):  
Physical Activity ◽  
Risk Factors ◽  
Cohort Study ◽  
Cognitive Function ◽  
Sedentary Behaviour ◽  
Phase Ii ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Related Potentials

IntroductionAlthough studies showed that physical activity (PA) and sedentary behaviour (SB) were associated with cardiometabolic risk factors and cognitive function, both independent and combined associations among them are inconsistent. Cardiometabolic risk factors are also associated with cognitive function, but research of children is limited. Additionally, the brain level mechanisms have not been fully established. The proposed study aims to explore the associations and mechanisms of PA and SB on cognitive function and cardiometabolic risk factors in children.Methods and analysisThis is a school-based prospective cohort study. A total of 8324 participants of this study are primary school students aged 7–12 years old who are followed up every 2 years from January 2017 to December 2026. We used a stratified cluster random sampling to select five primary schools in Guangzhou, China. There are three phases at baseline. At phase I, we collect PA, SB and cognitive function by questionnaires and also conduct anthropometric and biochemical measurements in all participants. At phase II, PA, SB and cognitive function are measured respectively by accelerometers and cognitive tasks among participants randomly selected from four subgroups with different SB and PA levels. At phase III, event-related potentials are recorded using electroencephalogram during a cognitive task among participants randomly selected from phase II. We plan to follow-up all participants until they graduate from high school. The process applied at baseline and follow-up are approximately identical.Ethics and disseminationProcedures described in this manuscript have been approved by the Ethical Review Committee for Biomedical Research, School of Public Health, Sun Yat-sen University (L2016-010). All parents or guardians of participants signed the informed consent form voluntarily before participating in the study. The findings of the study will be published in peer-reviewed journals.Trial registration numberNCT03582709

Dose–Response Association Between Physical Activity and Cognitive Function in a National Sample of Older Adults

2017 ◽  
Vol 32 (3) ◽  
pp. 554-560 ◽  
Author(s):  
Paul D. Loprinzi ◽  
Meghan K. Edwards ◽  
Elizabeth Crush ◽  
Toshikazu Ikuta ◽  
Alberto Del Arco
Keyword(s):  
Physical Activity ◽  
Older Adults ◽  
Cognitive Function ◽  
Dose Response ◽  
Vigorous Physical Activity ◽  
National Sample ◽  
Self Report ◽  
Favorable Effect ◽  
Digit Symbol Substitution Test ◽  
Metabolic Equivalent Of Task

Purpose: Previous research demonstrates a favorable effect of physical activity on cognitive function among older adults. The potential dose–response relationship between physical activity and cognitive function in this population is less understood, which was the purpose of this study. Setting: Data from the 1999 to 2002 National Health and Nutrition Examination Survey were employed. Participants: A total of 2157 older adults aged 60 to 85 years. Measures: Cognitive function was assessed from the Digit Symbol Substitution Test. Moderate-to-vigorous physical activity (MVPA), expressed as metabolic equivalent of task (MET)-min-month (MET-min-month = days × duration × MET level), was assessed via self-report, with 5 MVPA categories evaluated: (1) <2000 MVPA MET-min-month, (2) 2000 to 3999 MVPA MET-min-month, (3) 4000 to 5999 MVPA MET-min-month, (4) 6000 to 7999 MVPA MET-min-month, and (5) 8000+ MVPA MET-min-month. Analysis: Weighted multivariable linear regression. Results: An inverted U-shaped relationship was observed. Consistent across several adjusted models, those who engaged in 6000 to 7999 MVPA MET-min-month had the highest cognitive function score. Conclusion: The results suggest an optimal amount of physical activity to prevent the cognitive decline associated with aging.

Dose-response association of the duration and volume of physical activity with incident dementia: A cosmic collaborative cohort study

2021 ◽  
Vol 429 ◽  
pp. 119029
Author(s):  
Wanqing Wu ◽  
Ding Ding ◽  
Qianhua Zhao ◽  
Zhenxu Xiao ◽  
Mary Ganguli ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cohort Study ◽  
Dose Response ◽  
Incident Dementia

Dose-Response Issues Concerning the Relations Between Regular Physical Activity and Health

2002 ◽  
Author(s):  
Tuomo Rankinen ◽  
Claude Bouchard ◽  
Charles B. Corbin ◽  
Robert P. Pangrazi ◽  
Don Franks
Keyword(s):  
Physical Activity ◽  
Dose Response ◽  
Regular Physical Activity

HUBUNGAN AKTIVITAS FISIK DENGAN FUNGSI KOGNITIF LANSIA DI PANTI WREDHA YAYASAN SOSIAL SALIB PUTIH SALATIGA

2019 ◽  
pp. 137-143
Author(s):  
Dennys Christovel Dese ◽  
Cahyo Wibowo
Keyword(s):  
Physical Activity ◽  
Cognitive Function ◽  
The Elderly ◽  
Moderate Physical Activity ◽  
Cross Sectional ◽  
Significance Level ◽  
The Social ◽  
Normal Cognitive Function ◽  
Intellectual Capacity ◽  
Independent Variable

Peningkatan jumlah lansia setiap tahunnya harus dijadikan perhatian, akibat adanya peningkatan jumlah lansia masalah yang dihadapi akan menjadi semakin kompleks, salah satunya adalah masalah yang berkaitan dengan gejala penuaan. Menurunnya kapasitas intelektual berhubungan erat dengan fungsi kognitif pada lansia. Aktivitas fisik diidentifikasi sebagai salah satu faktor yang mempengaruhi fungsi kognitif. Aktivitas fisik bermanfaat untuk lansia sebagai pencegahan dan demensia. Penelitian ini merupakan penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Penelitian dilakukan di yayasan sosial Panti Wredha Salib Putih Salatiga pada bulan Juni 2018. Populasi dalam penelitian ini adalah lansia yang berumur ?60 tahun. Subjek pada penelitian ini berjumlah 16 responden. Variabel independen dalam penelitian ini adalah aktivitas fisik yang dinilai dengan menggunakan instrument GPAQ. Sedangkan variabel dependen dalam penelitian ini adalah fungsi kognitif yang dinilai dengan instrument MMSE. Terdapat 4 orang (25%) yang masuk dalam kategori fungsi kognitif normal dengan kategori aktifitas fisik sedang 1 orang dan aktifitas berat 3 orang, kemudian yang termasuk dalam kategori gangguan fungsi kognitif ringan sebanyak 11 orang (68,75%), dengan kategori aktifitas fisik sedang 8 orang dan aktifitas ringan 3 orang. Sedangkan yang termasuk dalam kategori gangguan fungsi kognitif berat, terdapat 1 orang (6,25%) dengan kategori aktifitasnya ringan. Taraf signifikansi antar variabel tingkat aktifitas fisik dan fungsi kognitif pada lansia adalah p=0.007 atau p<0,05, sehingga dapat disimpulkan ada  hubungan antara tingkat aktifitas fisik dengan fungsi kognitif pada lansia.   Increasing the number of elderly people every year should be a concern, due to an increase in the number of elderly problems faced will become increasingly complex, one of which is a problem related to the symptoms of aging. Decreased intellectual capacity is closely related to cognitive function in the elderly. Physical activity is identified as one of the factors that influence cognitive function. Physical activity is beneficial for the elderly as prevention and dementia. This study was an observational analytic study using a cross sectional approach. The study was conducted at the social foundation nursing home in the white cross in June 2018. The population in this study was elderly aged ≥60 years. The subjects in this study were 16 respondents. The independent variable in this study is physical activity that is assessed using the GPAQ instrument. While the dependent variable in this study was cognitive function which was assessed by the MMSE instrument. There are 4 people (25%) who fall into the category of normal cognitive function with moderate physical activity categories 1 person and heavy activities 3 people, then those included in the category of mild cognitive function disorders are 11 people (68.75%), with the category of physical activity being 8 people and 3 light activities. While those included in the category of severe cognitive function disorders, there is 1 person (6.25%) with a mild activity category. The significance level between the level of physical activity and cognitive function in the elderly is p = 0.007 or p <0.05, so it can be concluded that there is a relationship between the level of physical activity and cognitive function in the elderly.

Physical activity and cognitive function in older persons

2016 ◽  
Vol 64 (2) ◽  
Keyword(s):  
Physical Activity ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Executive Functions ◽  
Cognitive Aging ◽  
Clinical Studies ◽  
Older Persons ◽  
Positive Effects ◽  
Critical Challenge

Strategies to improve cognitive aging are highly needed. Among those, promotion of exercise and physical activity appears as one of the most attractive and beneficial intervention. Indeed, results from basic and clinical studies suggest that exercise and physical activity have positive effects on cognition in older persons without cognitive impairment, as well as in those with dementia. Despite inconsistent results, aerobic exercise appears to have the strongest potential to enhance cognition. However, even limited periods of walking (45 minutes, three times a week, over a 6-month period) have also been shown to enhance cognition, particularly executive functions. Changing long-term lifestyle habits in these older persons remains a critical challenge and attractive programs susceptible to gain adherence are needed to succeed in achieving improved cognitive aging.

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