Coinfection with Epstein–Barr Virus (EBV), Human Papilloma Virus (HPV) and Polyoma BK Virus (BKPyV) in Laryngeal, Oropharyngeal and Oral Cavity Cancer

The aim of this study was to analyze the prevalence of BK virus, Human Papillomavirus and Epstein-Barr virus in oropharyngeal cancer, and to test our hypothesis that BKV/HPV/EBV co-infection plays a role in oropharyngeal squamous cell carcinoma. The correlation between viral infection, OSCC, anatomic location, pre-treatment staging, evidence of metastases to lymph nodes, and grading was also investigated. The examination samples were collected from 62 patients from paraffin tissue blocks. Males (90.3%) with, smoking (83.9%) and alcohol abuse (67.7%) problems prevailed in the studied group. G2 histological type was recognized in 80.6% cases. T4 (77.4%) and N2 (56.5%) traits occurred in the majority of patients. No cases of metastasis were observed (M0 100%). HPV – 24.2%, EBV – 27.4% and BKV 17.7% were detected in the studied samples. We observed co-infection EBV/BKV in 8% of cases, HPV/BKV in 4.8%, and HPV/EBV in 9% cases. Only in two cases co-infection of all three viruses was found.

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Molecular Detection of Epstein Barr Virus, Human Papilloma Virus Types 16,18 in Breast Cancer Patients in Khartoum State Sudan

Novel Approaches in Cancer Study ◽

10.31031/nacs.2019.04.000576 ◽

2019 ◽

Vol 4 (1) ◽

Author(s):

Khalid A Enan

Keyword(s):

Breast Cancer ◽

Human Papilloma Virus ◽

Cancer Patients ◽

Epstein Barr Virus ◽

Molecular Detection ◽

Breast Cancer Patients ◽

Papilloma Virus ◽

Barr Virus ◽

Epstein Barr

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Immunohistochemical study of Human Papilloma Virus and Epstein–Barr virus in patients with lymphoepithelioma-like carcinoma of the uterine cervix

Archives of the Balkan Medical Union ◽

10.31688/abmu.2019.54.4.09 ◽

2019 ◽

Vol 54 (4) ◽

pp. 680-684

Author(s):

Angel D. YORDANOV ◽

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Milena D. KARCHEVA ◽

Tatiana M. BETOVA ◽

Ivan N. IVANOV ◽

...

Keyword(s):

Human Papilloma Virus ◽

Uterine Cervix ◽

Epstein Barr Virus ◽

Immunohistochemical Study ◽

Papilloma Virus ◽

Barr Virus ◽

Epstein Barr

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Demonstration of Epstein-Barr Virus DNA in Acetowhite Lesions of the Vulva

International Journal of STD & AIDS ◽

10.1177/095646249400500107 ◽

1994 ◽

Vol 5 (1) ◽

pp. 25-28 ◽

Cited By ~ 7

Author(s):

E Voog ◽

A Ricksten ◽

G B Löwhagen ◽

A Ternesten

Keyword(s):

Human Papilloma Virus ◽

Epstein Barr Virus ◽

Control Group ◽

Papilloma Virus ◽

Hpv Dna ◽

Barr Virus ◽

Oral Hairy Leukoplakia ◽

Hairy Leukoplakia ◽

Ebv Dna ◽

Epstein Barr

Acetowhite lesions in the vulva disclosing koilocytosis have been related to infection by human papilloma virus (HPV). Because of the clinical resemblance of these lesions to oral hairy leukoplakia (OHL), and EBV-manifestation, 23 women with acetowhite koilocytotic lesions in the vulva were examined. The PCR-technique was used to detect EBV DNA as well as HPV DNA in 17% of 23 patients examined. In a control group of 19 patients EBV DNA was detected in 11% and HPV DNA in 42% of cell samples from normal vulvar mucosa. EBV DNA has not previously been demonstrated in the vulvar mucosa, and this virus might be related to subclinical acetowhite lesions.

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