scholarly journals Regulation of microRNA Expression in Sleep Disorders in Patients with Epilepsy

2021 ◽  
Vol 22 (14) ◽  
pp. 7370
Author(s):  
Edyta Dziadkowiak ◽  
Justyna Chojdak-Łukasiewicz ◽  
Piotr Olejniczak ◽  
Bogusław Paradowski
Keyword(s):  
Sleep Disorders ◽  
Sleep Disorder ◽  
Diagnostic Tool ◽  
Main Role ◽  
Medical Database ◽  
Sleep Studies ◽  
Important Diagnostic Tool ◽  
Patients With Epilepsy ◽  
The Relationship

The effects of epilepsy on sleep and the activating effects of sleep on seizures are well documented in the literature. To date, many sleep-related and awake-associated epilepsy syndromes have been described. The relationship between sleep and epilepsy has led to the recognition of polysomnographic testing as an important diagnostic tool in the diagnosis of epilepsy. The authors analyzed the available medical database in search of other markers that assess correlations between epilepsy and sleep. Studies pointing to microRNAs, whose abnormal expression may be common to epilepsy and sleep disorders, are promising. In recent years, the role of microRNAs in the pathogenesis of epilepsy and sleep disorders has been increasingly emphasized. MicroRNAs are a family of single-stranded, non-coding, endogenous regulatory molecules formed from double-stranded precursors. They are typically composed of 21–23 nucleotides, and their main role involves post-transcriptional downregulation of expression of numerous genes. Learning more about the role of microRNAs in the pathogenesis of sleep disorder epilepsy may result in its use as a biomarker in these disorders and application in therapy.

scholarly journals Workaholism, Intensive Smartphone Use, and the Sleep-Wake Cycle: A Multiple Mediation Analysis

2019 ◽  
Vol 16 (19) ◽  
pp. 3517 ◽  
Author(s):  
Spagnoli ◽  
Balducci ◽  
Fabbri ◽  
Molinaro ◽  
Barbato
Keyword(s):  
Sleep Quality ◽  
Sleep Disorders ◽  
Daytime Sleepiness ◽  
Self Report ◽  
Poor Sleep ◽  
Multiple Mediation ◽  
Smartphone Use ◽  
The Relationship ◽  
Mediation Models

Recent contributions have reported sleep disorders as one of the health impairment outcomes of workaholism. A possible factor affecting the sleep-wake cycle might be the intensive use of smartphones. The current study aimed to explore the role of intensive smartphone use in the relationship between workaholism and the sleep-wake cycle. Two serial multiple mediation models were tested on a sample of 418 employees, who filled self-report questionnaires measuring workaholism, use of smartphones, sleep quality and daytime sleepiness, using conditional process analysis for testing direct and indirect effects. Results supported our hypotheses regarding two serial multiple mediation models—that intensive smartphone use and poor sleep quality mediated the relationship between workaholism and daytime sleepiness, and that smartphone use and daytime sleepiness mediated the relationship between workaholism and poor quality of sleep. Although the use of a cross-sectional design and the snowball technique for collecting data can be considered as possible limitations, the current study is one of the first to document the potential detrimental role of the intensive smartphone use on the workaholism-sleep disorders relationship.

SCORING SLEEP: THE RULES FOR LOOKING INSIDE

2015 ◽  
Vol 14 (3) ◽  
pp. 119-124
Author(s):  
Floriana Boghez ◽  
◽  
Ioana Mandruta ◽  
Keyword(s):  
Eye Movements ◽  
Sleep Disorders ◽  
Diagnostic Tool ◽  
Video Recording ◽  
Sleep Architecture ◽  
Sleep Stages ◽  
Sleep Study ◽  
Rapid Eye Movements ◽  
Cardiac Functions ◽  
Important Diagnostic Tool

Polysomnography is the most comprehensive sleep study, a multi-parametric recording test (electroencephalography, electrooculogram, chin and limbs electromyogram, respiratory and cardiac functions and permanent video-recording), used as an important diagnostic tool for the sleep disorders. Sleep architecture or the sleep macrostructure is a term used to describe the divisions of sleep into specific sleep stages using electro encephalographic (EEG), electrooculographic (EOG) and electromyographic (EMG) criteria: NREM (non-rapid eye movements) stages – N1, N2 and N3, and REM (rapid eye movements) stage.

Diagnosis of sleep and circadian rhythm disorder

2020 ◽  
pp. 1124-1136
Author(s):  
Kirstie Anderson
Keyword(s):  
Circadian Rhythm ◽  
Sleep Disorders ◽  
Sleep Disorder ◽  
Eye Movement ◽  
Nrem Sleep ◽  
Rapid Eye Movement ◽  
Sleep Diaries ◽  
Circadian Rhythm Disorder ◽  
Rhythm Disorder

The diagnosis of sleep and circadian rhythm disorders provides a detailed framework to correctly diagnose the primary sleep disorders that a psychiatrist will see in daily practice, including common sleep-related movement disorders. This includes the specific sleep history, the role of sleep diaries, validated questionnaires, and how to interpret the scores and the role of both home and inpatient sleep studies (polysomnography). The most recent diagnostic criteria within the International Classification of Sleep Disorder, third edition (ICSD-3) are used for the four major categories of sleep disorder: hypersomnia, insomnia, parasomnia, and circadian rhythm disorder. Common sleep disorders such as obstructive sleep apnoea (OSA), restless legs syndrome (RLS), narcolepsy, and both non-rapid eye movement (NREM) sleep parasomnia and rapid eye movement (REM) parasomnia are described. It is written for qualified specialist doctors.

scholarly journals Studying about the family's role in taking care of the elderly in Vietnam today - Through the research in elderly care homes in Ho Chi Minh city

2020 ◽  
Vol 4 (2) ◽  
pp. 324-335
Author(s):  
Nguyen Thi Hoai Chau
Keyword(s):  
Population Aging ◽  
Elderly Care ◽  
Care Homes ◽  
Ho Chi Minh City ◽  
Main Role ◽  
Traditional Role ◽  
The Family ◽  
The Impact ◽  
The Relationship

Population aging is the most important trend of the 21st century in the world. Vietnam has officially entered the period of population aging since 2014 with the fastest aging rate. “Population aging” is a noticeable topic in Vietnam today. And in fact, according to many researchers, the number, especially the number of in-depth researches and applicable researches are still limited. Based on the inheriting of precedence researches and the result of my fieldwork study conducted in nursing homes in Ho Chi Minh city, from a new viewpoint, the paper aims to explore the traditional role of elderly care of the family in relationship with using nursing home today. Until now, the traditional family has played the main role in elderly care in Vietnam. In the context of changing society under the impact of urbanization and industrialization today, studying about the traditional role of elderly care of family, the relationship between family and the trend of "socialization" of elderly care, the changes and predicted future trend when compared with Japan, etc. would be necessary. The research result shows that the Vietnamese still have a strong negative attitude toward elderly care homes, and the traditional role of the family of elderly care is still deeply maintained. But at the same time, some basic changes have also confirmed, such as the change in traditional filial piety, the strengthening of the role of social services such as elderly care homes, etc. It can be said that this is the outstanding characteristic of the status of elderly care in Vietnam today. And based on comparing with other countries, the study also shows that in order to find an effective elderly care model in Vietnam, it is necessary to pay much attention to the relationship with the family.

scholarly journals Invasive hemodynamic assessment of patients with cardiomyopathies

2021 ◽  
Vol 27 (4) ◽  
pp. 16-29
Author(s):  
Monika Shumkova ◽  
Kiril Karamfiloff ◽  
Raya Ivanova ◽  
Dobrin Vassilev
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiac Catheterization ◽  
Diagnostic Tool ◽  
Cardiac Diseases ◽  
Advantages And Disadvantages ◽  
Non Invasive ◽  
Hemodynamic Assessment ◽  
Important Diagnostic Tool ◽  
Invasive Diagnostics

Invasive hemodynamic assessment of cardiac diseases has become an important diagnostic tool in recent decades. Non-invasive methods are the main techniques used to assess cardiac function, due to their wider availability. Cardiac catheterization is useful when there are diagnostic problems that cannot be solved with routine methods. Cardiac catheterization should be individualized according to the specific problems of the patient and based on the results from non-invasive methods. Invasive diagnostics is used in the assessment of patients with various cardiovascular diseases, including cardiomyopathies. In this review, we consider the role of cardiac catheterization, its advantages and disadvantages as part of the overall assessment of patients with cardiomyopathies.  

The Impact of Spleen Disorders in the Pathogenesis of Anemia from the Viewpoint of Persian Medicine

2020 ◽  
Author(s):  
Somaye Fatali ◽  
Amir Hossein Emami ◽  
Majid Dadmehr ◽  
Mitra Mehrabani ◽  
Saeideh Yarjoo ◽  
...  
Keyword(s):  
Reticuloendothelial System ◽  
Main Role ◽  
Persian Medicine ◽  
Data Saturation ◽  
Traditional Persian Medicine ◽  
Main Components ◽  
The Impact ◽  
The Relationship ◽  
High Incorporation

Spleen is one of the main components of reticuloendothelial system and plays an important role in controlling of red blood cell quality with elimination of old and damaged cells. Physicians of Traditional Persian Medicine believed that spleen has a high incorporation with the liver, and liver has a main role in blood production. So its pathologic changes influence the production of hematologic elements in both aspects of amount and quality. In this study, chapters related to spleen disease in several Traditional Persian Medicine textbooks and available databases were reviewed. Further the relationship between anemia and spleen diseases were derived and evaluated. After interviewing two experts about the findings and reaching data saturation, the results were compiled and explained. Spleen dysfunction and diseases can lead to anemia, because of intercommunity with liver. This happens with different mechanisms such as: enlargement, cold distemperment, asthenia and crisis. Although there are many studies so far about anemia, but role of the spleen in the development of anemia is still not well known. Considering the role of the spleen in developing anemia, the drugs used in Persian medicine for spleen-originated anemia may provide an appropriate solution to treat the disease.

scholarly journals Can Work Engagement Be a Resource for Reducing Workaholism’s Undesirable Outcomes? A Multiple Mediating Model Including Moderated Mediation Analysis

2019 ◽  
Vol 16 (8) ◽  
pp. 1402 ◽  
Author(s):  
Liliya Scafuri Kovalchuk ◽  
Carmela Buono ◽  
Emanuela Ingusci ◽  
Francesco Maiorano ◽  
Elisa De Carlo ◽  
...  
Keyword(s):  
Sleep Disorders ◽  
Emotional Exhaustion ◽  
Work Engagement ◽  
Family Conflict ◽  
Mediation Model ◽  
Multiple Mediation ◽  
Work Family Conflict ◽  
Work Family ◽  
The Relationship

This study aimed to explore a possible process explaining the relationship between workaholism and sleep disorders, including two mediators: work–family conflict and emotional exhaustion. Moreover, since a possible buffering role of work engagement was recently proposed against the detrimental effects of workaholism, the aim was to examine the moderating role of work engagement in the relationship between workaholism and several outcomes such as work–family conflict, emotional exhaustion, and sleep disorders. Two models were tested using conditional process analysis for testing direct and indirect effects on a sample of 395 employees: (1) a serial multiple mediation model, and (2) the same serial multiple mediation model including the moderating role of work engagement. Results showed a significant mediating effect of both work–family conflict and emotional exhaustion. Moreover, work engagement moderated the relationship between workaholism and work–family conflict and the relationship between workaholism and emotional exhaustion. This work contributes to the understanding of the process underlying the relationship between workaholism and sleep disorders and to the literature reporting the possible protective role of work engagement on the negative outcomes of workaholism. Practical implications are also discussed.

scholarly journals Role of ultrasound in diagnosis and differentiation of benign and malignant ovarian mass: A Hospital based study in Western Nepal

2019 ◽  
Vol 10 (5) ◽  
pp. 86-89
Author(s):  
Subash KC ◽  
Ashish Shrestha ◽  
Sagar Khadka ◽  
Ramesh Poudel
Keyword(s):  
Diagnostic Tool ◽  
Histopathological Diagnosis ◽  
Ovarian Mass ◽  
Female Population ◽  
Histopathological Findings ◽  
Important Diagnostic Tool ◽  
Sensitivity Specificity ◽  
A Prospective Study ◽  
Ovarian Masses

Background: As ovarian malignancies are one of the commonest malignancies in female population, timely and accurate diagnosis helps in early treatment resulting in better survival. Ultrasound is easily available diagnostic tool not only to diagnose but also accurately distinguish malignant from benign ovarian masses. Aims and Objectives: To evaluate sensitivity, specificity and accuracy of ultrasound in diagnosing and differentiating benign from malignant ovarian masses in comparison with histopathological findings. Materials and Methods: A prospective study was carried out from August 2015 to August 2018 for a period of 3 years. Total 150 patients with ovarian masses who were operated in our hospital and their final histopathological reports were available, were included in our study. Ultrasound diagnosis and histopathological diagnosis were compared. Results: Sensitivity, specificity and accuracy of ultrasound in diagnosing and differentiating malignant from benign ovarian masses were found to be 78.94%, 98.47% and 88.23% respectively compared with histopathological findings. Conclusion: Ultrasound is very sensitive, specific and accurate in not only diagnosing ovarian mass but also in differentiating malignant from benign entities making it invaluable and important diagnostic tool in evaluation of ovarian masses.

scholarly journals Insomnia among Prison Officers and Its Relationship with Occupational Burnout: The Role of Coping with Stress in Polish and Indonesian Samples

2021 ◽  
Vol 18 (8) ◽  
pp. 4282
Author(s):  
Ewa Sygit-Kowalkowska ◽  
Andrzej Piotrowski ◽  
Imaduddin Hamzah
Keyword(s):  
Sleep Disorders ◽  
Help Seeking ◽  
Total Sample ◽  
Coping With Stress ◽  
Occupational Burnout ◽  
Mediating Role ◽  
Athens Insomnia Scale ◽  
Oldenburg Burnout Inventory ◽  
The Relationship

Thus far, data on sleep disorders among prison officers (POs) have been scarce. Research allows us to relate this problem to occupational stress, which POs experience every day. The aim of the current study was to analyze the scale, predictors, and impact of select factors on the relationship between insomnia and occupational burnout. This study was carried out on a sample of 376 Indonesian and 288 Polish POs using the Athens Insomnia Scale (AIS), the Coping Orientation to Problems Experienced (COPE) inventory, and the Oldenburg Burnout Inventory (OLBI). Results showed that 43.4% of the Polish sample exhibited early symptoms of insomnia, compared to 26.1% of the Indonesian sample. Sleep disorders had a significant role in developing occupational burnout. In both samples, coping strategies such as help-seeking and engagement were revealed to have a mediating role in the relationship between insomnia and occupational burnout dimensions. For the total sample and for the Polish sample, the coping strategy of help-seeking was the only predictor of insomnia. Discrepancies (concerning the role of age, gender, and multi-shift work) were observed between the current results and earlier studies. The current study’s limitations were discussed and new solutions were proposed.

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