scholarly journals Invasive hemodynamic assessment of patients with cardiomyopathies

2021 ◽  
Vol 27 (4) ◽  
pp. 16-29
Author(s):  
Monika Shumkova ◽  
Kiril Karamfiloff ◽  
Raya Ivanova ◽  
Dobrin Vassilev
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiac Catheterization ◽  
Diagnostic Tool ◽  
Cardiac Diseases ◽  
Advantages And Disadvantages ◽  
Non Invasive ◽  
Hemodynamic Assessment ◽  
Important Diagnostic Tool ◽  
Invasive Diagnostics

Invasive hemodynamic assessment of cardiac diseases has become an important diagnostic tool in recent decades. Non-invasive methods are the main techniques used to assess cardiac function, due to their wider availability. Cardiac catheterization is useful when there are diagnostic problems that cannot be solved with routine methods. Cardiac catheterization should be individualized according to the specific problems of the patient and based on the results from non-invasive methods. Invasive diagnostics is used in the assessment of patients with various cardiovascular diseases, including cardiomyopathies. In this review, we consider the role of cardiac catheterization, its advantages and disadvantages as part of the overall assessment of patients with cardiomyopathies.  

scholarly journals Evaluation of endothelial dysfunction and the possibility of its correction at the present stage in patients with cardiovascular diseases

Kardiologiia ◽  
2019 ◽  
Vol 59 (3S) ◽  
pp. 4-9 ◽  
Author(s):  
M. O. Samolyuk ◽  
N. Yu. Grigorieva
Keyword(s):  
Quality Of Life ◽  
Nitric Oxide ◽  
Cardiovascular Diseases ◽  
Endothelial Dysfunction ◽  
Mortality Rates ◽  
Present Stage ◽  
Advantages And Disadvantages ◽  
Complications And Mortality

The review describes the current understanding of endothelial dysfunction, methods of its evaluation, and highlights the advantages and disadvantages of various techniques. The role of nitric oxide and endothelin as important markers of endothelial dysfunction is shown, and the methods of their determination in clinical practice are described. The authors conclude that in order to improve the life expectancy and quality of life of patients with cardiovascular diseases, reduce the risk and frequency of complications and mortality rates, it is necessary to study the function of endothelium in more detail and to look for ways of drug correction, taking into account the pathogenetic mechanisms of its formation. 

The Role of Musculoskeletal USG as Diagonostic Tool of CTS

2014 ◽  
Vol 25 (2) ◽  
pp. 44-49
Author(s):  
P Das ◽  
R Pramanik ◽  
M Kataruka ◽  
RN Haldar ◽  
S Samanta ◽  
...  
Keyword(s):  
Diagnostic Tool ◽  
Predictive Value ◽  
Low Cost ◽  
Large Population ◽  
Study Data ◽  
Cross Sectional ◽  
Non Invasive ◽  
Invasive Test ◽  
Kappa Value

Abstract Introduction Over the years NCS has been used to diagnose and monitor the patients with CTS though USG has several advantages as diagnostic tool. This study has been done to find out the diagnostic accuracy of USG in CTS and to compare the efficacy of USG with standard NCS in CTS. Prospective cross-sectional analytical study was conducted at Dept. of PM&R, IPGME&R, Kolkata from 1st March, 2012 to 31st August 2012 (6 months). Patient with clinical diagnosis of CTS of age >18 year of both sexes were included in this study and on the other hand patient with previous wrist surgery /injury, wrist deformity, diabetes mellitus, anatomical variants of median nerve on ultrasound were excluded from the study. Methodology After getting institutional ethical committee clearance, all patients who fulfil the above criteria were included in the study and further diagnostic conformation done by the standard diagnostic criteria of NCS. The same group of patients have been also screened by ultrasonography (USG). Results At the end of the study, data analysis showed that sensitivity and specificity were 92.3 and 70.0% respectively. Predictive value of +test, predictive value of -test were 88.9 and 77.8% respectively. Kappa value was 0.64 (between 0.5 and 0.7). It signifies that there is good correlation between NCS and USG as diagnostic tool of CTS. The comparison of the numerical values of median latency, amplitude and CSA USG within the groups with the help of ANOVA followed by Tukey's test showed that there was good correlation between latency and amplitude in mild, moderate, severe and profound CTS but unfortunately it was not correlated with the CSA measured by USG. Conclusion USG can be used for screening large population of patients as it is simple, easily available, non-invasive test and has relatively low cost and useful in evaluating and excluding local causes of nerve compression.

scholarly journals Role of ultrasound in diagnosis and differentiation of benign and malignant ovarian mass: A Hospital based study in Western Nepal

2019 ◽  
Vol 10 (5) ◽  
pp. 86-89
Author(s):  
Subash KC ◽  
Ashish Shrestha ◽  
Sagar Khadka ◽  
Ramesh Poudel
Keyword(s):  
Diagnostic Tool ◽  
Histopathological Diagnosis ◽  
Ovarian Mass ◽  
Female Population ◽  
Histopathological Findings ◽  
Important Diagnostic Tool ◽  
Sensitivity Specificity ◽  
A Prospective Study ◽  
Ovarian Masses

Background: As ovarian malignancies are one of the commonest malignancies in female population, timely and accurate diagnosis helps in early treatment resulting in better survival. Ultrasound is easily available diagnostic tool not only to diagnose but also accurately distinguish malignant from benign ovarian masses. Aims and Objectives: To evaluate sensitivity, specificity and accuracy of ultrasound in diagnosing and differentiating benign from malignant ovarian masses in comparison with histopathological findings. Materials and Methods: A prospective study was carried out from August 2015 to August 2018 for a period of 3 years. Total 150 patients with ovarian masses who were operated in our hospital and their final histopathological reports were available, were included in our study. Ultrasound diagnosis and histopathological diagnosis were compared. Results: Sensitivity, specificity and accuracy of ultrasound in diagnosing and differentiating malignant from benign ovarian masses were found to be 78.94%, 98.47% and 88.23% respectively compared with histopathological findings. Conclusion: Ultrasound is very sensitive, specific and accurate in not only diagnosing ovarian mass but also in differentiating malignant from benign entities making it invaluable and important diagnostic tool in evaluation of ovarian masses.

scholarly journals VP48.01: The role of non‐invasive hemodynamic assessment in patients with preterm premature rupture of the membranes

2020 ◽  
Vol 56 (S1) ◽  
pp. 279-280
Author(s):  
F. Pometti ◽  
D. Farsetti ◽  
I. Pisani ◽  
G. Tiralongo ◽  
D. Lo Presti ◽  
...  
Keyword(s):  
Premature Rupture ◽  
Non Invasive ◽  
Preterm Premature Rupture ◽  
Hemodynamic Assessment

scholarly journals NFkappaB is a Key Player in the Crosstalk between Inflammation and Cardiovascular Diseases

2019 ◽  
Vol 20 (7) ◽  
pp. 1599 ◽  
Author(s):  
Antonella Fiordelisi ◽  
Guido Iaccarino ◽  
Carmine Morisco ◽  
Enrico Coscioni ◽  
Daniela Sorriento
Keyword(s):  
Cardiovascular Diseases ◽  
Cardiovascular Events ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Cardiac Diseases ◽  
Functional Link ◽  
Therapeutic Targeting ◽  
Potential Strategy ◽  
Transcription Factor Nfκb

Inflammation is a key mechanism of cardiovascular diseases. It is an essential component of atherosclerosis and a significant risk factor for the development of cardiovascular events. In the crosstalk between inflammation and cardiovascular diseases, the transcription factor NFκB seems to be a key player since it is involved in the development and progression of both inflammation and cardiac and vascular damage. In this review, we deal with the recent findings of the role of inflammation in cardiac diseases, focusing, in particular, on NFκB as a functional link. We describe strategies for the therapeutic targeting of NFκB as a potential strategy for the failing heart.

scholarly journals Regulation of microRNA Expression in Sleep Disorders in Patients with Epilepsy

2021 ◽  
Vol 22 (14) ◽  
pp. 7370
Author(s):  
Edyta Dziadkowiak ◽  
Justyna Chojdak-Łukasiewicz ◽  
Piotr Olejniczak ◽  
Bogusław Paradowski
Keyword(s):  
Sleep Disorders ◽  
Sleep Disorder ◽  
Diagnostic Tool ◽  
Main Role ◽  
Medical Database ◽  
Sleep Studies ◽  
Important Diagnostic Tool ◽  
Patients With Epilepsy ◽  
The Relationship

The effects of epilepsy on sleep and the activating effects of sleep on seizures are well documented in the literature. To date, many sleep-related and awake-associated epilepsy syndromes have been described. The relationship between sleep and epilepsy has led to the recognition of polysomnographic testing as an important diagnostic tool in the diagnosis of epilepsy. The authors analyzed the available medical database in search of other markers that assess correlations between epilepsy and sleep. Studies pointing to microRNAs, whose abnormal expression may be common to epilepsy and sleep disorders, are promising. In recent years, the role of microRNAs in the pathogenesis of epilepsy and sleep disorders has been increasingly emphasized. MicroRNAs are a family of single-stranded, non-coding, endogenous regulatory molecules formed from double-stranded precursors. They are typically composed of 21–23 nucleotides, and their main role involves post-transcriptional downregulation of expression of numerous genes. Learning more about the role of microRNAs in the pathogenesis of sleep disorder epilepsy may result in its use as a biomarker in these disorders and application in therapy.

scholarly journals Role of Chemiluminescence examination as non-invasive diagnostic tool in early detection of Leukoplakia

2018 ◽  
Vol 8 (3) ◽  
pp. 177-181 ◽  
Author(s):  
Nidhi Jain ◽  
Anil Kumar Nagarajappa ◽  
Meenakshi Bhasin ◽  
Divya Pandya ◽  
Kaushal Pati Tripathi
Keyword(s):  
Early Detection ◽  
Diagnostic Tool ◽  
Non Invasive

scholarly journals Role of the cerebral ultrasound in a case of Sturge-Weber syndrome

2019 ◽  
Vol 12 (4) ◽  
pp. e227834
Author(s):  
Ana Ferraz ◽  
Sofia Morais ◽  
Gabriela Mimoso
Keyword(s):  
Diagnostic Tool ◽  
Brain Abnormalities ◽  
Non Invasive ◽  
Weber Syndrome ◽  
Cerebral Ultrasound ◽  
Sturge Weber Syndrome ◽  
Brain Involvement

Cerebral ultrasound (CUS) can be a valuable non-invasive diagnostic tool for brain involvement in Sturge-Weber syndrome (SWS). Literature discussing the relevance of ultrasound in SWS is, however, scarce.We report a case of a newborn with SWS and serious brain abnormalities diagnosed on the first day of life with a CUS.

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