scholarly journals Effect of Gender, Age, and Ocular and Growth-Related Factors on Corneal Epithelial and Stromal Thickness in Children

2020 ◽  
Vol 9 (12) ◽  
pp. 3849
Author(s):  
Wook Kyum Kim ◽  
Ik Hee Ryu ◽  
Jeongseo Yoo ◽  
Sun Woong Kim
Keyword(s):  
Body Weight ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Axial Length ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Corneal Epithelial ◽  
Corneal Epithelial Thickness ◽  
Corneal Refractive Power

Data on corneal epithelial and stromal thickness in school-aged children in relation to gender, age, and ocular and growth parameters are limited. In this retrospective study, we analyzed corneal epithelial and stromal thickness measured with the RTVue system (Optovue, Inc., Fremont, CA, USA) in 122 male and 201 female Korean children (mean age 9.59 ± 2.18 years) with myopia. We used simple and multiple regression analysis to establish the relationships between gender, age, refractive status, axial length, anterior chamber depth (ACD), corneal refractive power, white-to-white corneal diameter (WTW), height, and body weight. Age, body weight, height, and central corneal thickness were positively associated with corneal epithelial thickness, whereas WTW was negatively associated. The multiple regression analysis showed corneal epithelial thickness was affected by sex, body weight, WTW, and central corneal thickness (CCT), while stromal thickness was influenced by age, sex, and WTW. Both corneal epithelial and stromal thickness were significantly greater in male than in female children and were affected by growth. Neither corneal epithelial nor stromal thickness were associated with the severity of myopia, corneal refractive power, or axial length.

scholarly journals Changes in Corneal Epithelial Thickness Induced by Topical Antiglaucoma Medications

2021 ◽  
Vol 10 (16) ◽  
pp. 3464
Author(s):  
Myungsik Nam ◽  
Sun Woong Kim
Keyword(s):  
Regression Analysis ◽  
Multiple Regression ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Thickness Measurement ◽  
Control Group ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness ◽  
Β Blockers

Corneal thickness measurement is important for assessing intraocular pressure in patients with glaucoma. This study investigated the changes in corneal epithelial thickness (CET) induced by antiglaucoma medications and explored the factors affecting CET measurement. CET was measured over a 9.0 mm diameter area by using Fourier domain optical coherence tomography in 125 patients with primary open-angle glaucoma and 125 age-matched controls without glaucoma. The influence of sex, age, benzalkonium chloride (BAK)-containing instillations, disease severity, and types and numbers of medications was analyzed using simple and multiple regression analyses. CET over 25 sectors was smaller in the glaucoma group than in the control group (mean difference of 4.2 µm in the central 2.0 mm zone; 52.8 ± 3.6 vs. 48.5 ± 3.9, p < 0.001). Simple regression analysis revealed age, use of β-blockers, prostaglandin, carbonic anhydrase inhibitors, total number of medications, and number of daily BAK-containing instillations were associated with a thinner epithelium. Multiple regression analysis revealed β-blockers, prostaglandin, and number of BAK-containing instillations were significant factors. Use of β-blockers and number of BAK-containing instillations were also associated with a thinner epithelium in the monotherapy subgroup analysis. CET was significantly smaller in patients with glaucoma receiving topical medications and was affected by the use of β-blockers, prostaglandin, and BAK.

Application of multiple regression analysis to morphometric characters obtained from Serranus cabrilla (linnaeus, 1758) by using stepwise method

2017 ◽  
Author(s):  
Levent Sangün ◽  
O. Ýnanç Güney
Keyword(s):  
Body Weight ◽  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
The Body ◽  
Stepwise Multiple Regression ◽  
Morphometric Characters ◽  
Independent Variables ◽  
Fisheries Science ◽  
Stepwise Method

In fisheries science, high number of morphometric measures (independent variables) taken from different parts of the fish complicates the estimation of the body weight (dependent variable). Therefore, the researchers are seeking for a solution facilitating the interpretation of the equations of correlation between the characteristics. One way to deal with this challenge is the dimension reduction by means of stepwise multiple regression analysis. The aim of this study is to explain total variation with the same accuracy by using fewer independent variables. To accomplish this, 12 morphometric measures from 210 individuals of Serranus cabrilla were measured to estimate the body weight. Firstly, the 95% of the variation was explained by means of multiple regression analysis by using all variables. Then, by step-wise method, the same results were achieved with fewer independent variables. Finally, the variables with inter-multicollinearity eliminated and with two remaining independent variables determination coefficients resulted as 95%. The result showed that using more variables does not create significant distinction for accuracy to estimate the body weight although; the total length and body dept was the most effective features for weight.

Effects of topical antiglaucomatous medications on central corneal epithelial thickness by anterior segment optical coherence tomography

2020 ◽  
Vol 30 (6) ◽  
pp. 1519-1524
Author(s):  
Emine Doğan ◽  
Burçin Köklü Çakır ◽  
Nilgün Özkan Aksoy ◽  
Erkan Celik ◽  
Ünal Erkorkmaz
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Tear Film ◽  
Optical Coherence ◽  
Corneal Epithelial ◽  
Duration Of Therapy ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness

Purpose: To evaluate the effect of topical antiglaucomatous medications on central corneal epithelial thickness measured by anterior segment optical coherence tomography. Materials and methods: A total of 153 eyes of 153 patients using topical antiglaucomatous medications and 110 eyes of 110 control subjects were enrolled. Glaucoma type, duration of therapy, the number of drugs, and drops/day were noted in the patient group. Patients and control subjects underwent ocular examinations including Schirmer test, slit lamp examination for tear film break-up time, and anterior segment optical coherence tomography for central corneal thickness and central corneal epithelial thickness. Central corneal epithelial thickness and other data were evaluated separately with regard to glaucoma type, duration of therapy, the number of drops, and drugs in the patient group. Results: The mean ages of the patients and controls were 60.1 ± 10.8 and 58.7 ± 11.2 years, respectively. The groups were similar with regard to mean age and gender (p = 0.058, p = 0.734, respectively). The median (interquartile range) central corneal thickness was 536 (54) µm in patients and 552 (53) µm in controls (p = 0.011). The median (interquartile range) central corneal epithelial thickness of patients and controls were 56 (4) µm and 60 (8) µm, respectively (p < 0.001). The median (interquartile range) tear film break-up time and Schirmer were 12 (6) s and 10 (8) mm in patients and 16 (2) s and 18 (4) mm in controls, respectively (p < 0.001, p < 0.001). In patient group, there was no significant difference in the median central corneal thickness, central corneal epithelial thickness, and tear film break-up time in terms of glaucoma type, duration of therapy, the number of drugs, and the number of daily drops. Only the median Schirmer test was found to be statistically lower in terms of number of daily eye drops (p = 0.039). Conclusion: Using topical antiglaucomatous medications seems to affect the central corneal epithelial thickness in glaucoma patients. Central corneal epithelial thickness was thinner in glaucoma patients than controls. Anterior segment optical coherence tomography might be helpful to evaluate the effect of antiglaucomatous medications on central corneal epithelial thickness during treatment.

scholarly journals Epithelial and stromal remodelling following femtosecond laser–assisted stromal lenticule addition keratoplasty (SLAK) for keratoconus

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mario Nubile ◽  
Niccolò Salgari ◽  
Jodhbir S. Mehta ◽  
Roberta Calienno ◽  
Emanuele Erroi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Observational Study ◽  
Femtosecond Laser ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Corneal Epithelial ◽  
Cadaveric Donor ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness

AbstractThe purpose of this study was to evaluate corneal epithelium and stromal remodelling with anterior segment optical coherence tomography in patients who have undergone stromal lenticule addition keratoplasty (SLAK) for advanced keratoconus. This was a prospective non-comparative observational study. Fifteen eyes of 15 patients with advanced keratoconus underwent implantation with a cadaveric, donor negative meniscus-shaped intrastromal lenticule, produced with a femtosecond laser, into a stromal pocket dissected in the recipient cornea at a depth of 120 μm. Simulated keratometry, central corneal thickness (CTT), corneal thinnest point (CTP), central epithelial thickness (CET), central and peripheral lenticule thickness, anterior and posterior stromal thickness were measured. Regional central corneal epithelial thickness (CET) and variations in the inner annular area (IAT) and outer annular area (OAT) were also analysed. All parameters were measured preoperatively and 1, 3, and 6 months postoperatively. The average anterior Sim-k decreased from 59.63 ± 7.58 preoperatively to 57.19 ± 6.33 D 6 months postoperatively. CCT, CTP, CET, and OAT increased and IAT decreased significantly after 1 month. All parameters appeared unchanged at 6-months except that of OAT that further increased. Lenticule thickness was stable. In conclusion we observed that SLAK reshapes the cornea by central flattening with stromal thickening and epithelial thickness restoration.

Gentamicin Pharmacokinetics in Postpartum Women with Endomyometritis

DICP ◽  
1991 ◽  
Vol 25 (12) ◽  
pp. 1306-1309 ◽  
Author(s):  
Myrna Y. Munar ◽  
Lisa A. Lawson ◽  
Philip Samuels ◽  
Gene A. Gibson
Keyword(s):  
Body Weight ◽  
Regression Analysis ◽  
Steady State ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Total Body Weight ◽  
Pharmacokinetic Parameters ◽  
Postpartum Women ◽  
The Mean ◽  
Total Body

The pharmacokinetics of gentamicin in postpartum women with endomyometritis were characterized and models for predicting patient pharmacokinetic parameters were developed using multiple regression analysis. Fifty-one women 13–34 years of age received gentamicin in combination with either ampicillin or clindamycin to treat endomyometritis. Forty-three women delivered by cesarean section and 8 women had vaginal deliveries. Gentamicin serum concentrations were determined at steady-state to compute the elimination rate constant (Ke), half-life (t1/2), apparent volume of distribution (Vd), and total body clearance (Cl). Gentamicin dosages were individualized using a one-compartment intermittent infusion model to achieve steady-state peak and trough concentrations of 6.5 and <2 μg/mL, respectively. The mean gentamicin t1/2 was 2.8 ± 0.9 h; the mean apparent Vd was 21 ± 8 L; and the mean total body Cl was 89.5 ± 31.7 mL/min. Multiple regression analysis revealed that total body weight (TBW) was the best predictor for the apparent Vd, described by the equation Vd = 0.146 TBW + 8.153 (r=0.56, p=0.00005). Total body weight and creatinine clearance (Clcr) were included as predictors for total body Cl, described by the equation Cl = 0.264 TBW + 0.337 Clcr + 3.416 (r=0.68, p=0.00005). Age and serum creatinine (SCr) were included in the models for the Ke, described by the equation Ke = −3.770 · 10−3 age — 0.115 SCr + 0.449 (r=0.42, p<0.004). Additional patient factors need to be identified to explain the variance in these pharmacokinetic parameters.

Pengaruh Citra Merek, Kualitas Produk Dan Harga Terhadap Kepuasan Konsumen Pada Bisnis Franchise Minuman

2017 ◽  
Vol 24 (2) ◽  
pp. 144-153
Author(s):  
Yunita Fitri Wahyuningtyas
Keyword(s):  
Regression Analysis ◽  
Marketing Strategy ◽  
Product Quality ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Sampling Method ◽  
Sampling Technique ◽  
Sampling Process ◽  
And Function ◽  
Simultaneous Influence

This research is conducted upon the emergence of many companies producing the same product of the same kind and function. It leads to the urgency of proper and well planned marketing strategy. This research aims to investigate how far the influence of branding, product quality, and price toward consumer’s satisfaction in beverage franchise business. This research utilizes 5 likert scale questionnaire which is tested by using multiple regression analysis to reveal whether or not there is partial and simultaneous influence of branding, product quality, and price toward consumer’s satisfaction in beverage franchise business. Sampling method is accidental sampling technique, in which sample of particular population is taken based on the accessibility and availability of the sample during the sampling process. Sample used is 100 samples among consumers or customers of Mang Endy Milkshake. The result shows that branding, product quality, and price influence consumer’s satisfaction in beverage franchise business.

Significance of Experience, Farm Size, Quantity of Propagules and Location f or Seaweed Farmers in the Divided Island of Sebatik

2018 ◽  
Vol 9 (9) ◽  
pp. 825-832
Author(s):  
James M. Alin ◽  
◽  
Datu Razali Datu Eranza ◽  
Arsiah Bahron ◽  
◽  
...  
Keyword(s):  
Regression Analysis ◽  
Multiple Regression Analysis ◽  
Multiple Regression ◽  
Production Function ◽  
Weather Conditions ◽  
Education Level ◽  
Farm Size ◽  
Total Production ◽  
Explanatory Factors ◽  
Douglas Production Function

Seaweed-Kappaphycus-Euchema Cottonii and Denticulum species was first cultivated at Sabah side of Sebatik in 2009. By November 2014, sixty one Sabahan seaweed farmers cultivated 122 ha or 3,050 long lines. Thirty Sabahan seaweed farmers in Kampung Pendekar (3.2 m.t dried) and 31 in Burst Point (12.5 m.t dried) produced 16 metric tonnes of dried seaweed contributed 31% to Tawau’s total production (51 m.t). The remaining 69% were from farmers in Cowie Bay that separates Sebatik from municipality of Tawau. Indonesian in Desa Setabu, Sebatik started in 2008. However, the number of Indonesian seaweed farmers, their cultivated areas and production (as well as quality) in Sebatik increased many times higher and faster than the Sabah side of Sebatik. In 2009 more than 1,401 households in Kabupaten Nunukan (including Sebatik) cultivated over 700 ha and have produced 55,098.95 and 116, 73 m.t dried seaweed in 2010 and 2011 respectively. There is a divergence in productions from farming the sea off the same island under similar weather conditions. Which of the eight explanatory factors were affecting production of seaweeds in Sebatik? Using Cobb Douglas production function, Multiple Regression analysis was conducted on 100 samples (50 Sabahan and 50 Indonesian). Results; Variable significant at α = 0.05% are Experience in farming whereas Farm size; Quantity of propagules and Location — Dummy are the variables significant at α 0.01%. Not significant are variables Fuel; Age; Number of family members involved in farming and Education level.

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