scholarly journals Effect of a Single Session of Tai Chi Chuan Practice on Glucose and Lipid Metabolism and Related Hormones

Life ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 145
Author(s):  
Wan-An Lu ◽  
Yung-Sheng Chen ◽  
Chun-Hsiung Wang ◽  
Cheng-Deng Kuo
Keyword(s):  
Insulin Resistance ◽  
Healthy Subjects ◽  
Tai Chi ◽  
Serum Insulin ◽  
Insulin Level ◽  
Serum Glucose ◽  
Healthy Controls ◽  
Serum Insulin Level ◽  
Tai Chi Chuan ◽  
Glucose And Lipid Metabolism

Background: To examine the effect of Tai Chi Chuan (TCC) practice on glucose and lipid metabolism and related hormones in TCC practitioners. Methods: Twenty-one TCC practitioners and nineteen healthy controls were included in this study. Classical Yang’s TCC was practiced by the TCC practitioners. The percentage changes in serum total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), serum glucose (SG), serum insulin, serum insulin level, homeostatic model assessment of insulin resistance (HOMA-IR), log(HOMA-IR), quantitative insulin sensitivity check index (QUICKI), and serum endothelin-1 (ET-1) before and 30 min after resting or TCC practice were compared between healthy controls and TCC practitioners. Results: Before TCC or resting, the serum insulin level, HOMA-IR, and log(HOMA-IR) of the TCC practitioners were significantly lower than those of healthy subjects, whereas the QUICKI of the TCC practitioners was significantly higher than that of healthy subjects. Thirty min after TCC practice, the %TC, %HDL-C, %QUICKI, and %ET-1 were all significantly decreased, whereas the %SG, %serum insulin, and %HOMA-IR were significantly increased in the TCC group as compared to the control group 30 min after resting. Conclusions: The serum glucose, insulin level and insulin resistance were enhanced, whereas the cholesterol, HDL-C and ET-1 levels were reduced 30 min after TCC practice. The mechanism underlying these effects of TCC 30 min after TCC is not clear yet.

'True' fasting serum insulin level, insulin resistance syndrome and coronary artery disease

1997 ◽  
Vol 8 (11) ◽  
pp. 683-688 ◽  
Author(s):  
Mostafa Chaour ◽  
Pierre Théroux ◽  
Brian M. Gilfix ◽  
Lucien Campeau ◽  
Jacques Lespérance ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Insulin ◽  
Insulin Level ◽  
Insulin Resistance Syndrome ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
Artery Disease

scholarly journals Comparison of Antidiabetic Effects of Aqueous Extract of the Leaves and Fruits of Avicennia Marina in Streptozotocin-induced Diabetic Male Rats

2019 ◽  
Vol 13 (2) ◽  
pp. 7-12
Author(s):  
Leila Kamaei ◽  
◽  
Davood Moghadamnia ◽  
Keyword(s):  
Sham Group ◽  
Serum Insulin ◽  
Insulin Level ◽  
Avicennia Marina ◽  
Serum Glucose ◽  
Diabetic Rats ◽  
Male Rats ◽  
Control Group ◽  
Serum Insulin Level ◽  
Rat Hearts

Background: In this study, the anti-diabetic effect of the extract of leaves and fruits of Avicennia marina (A. marina) in streptozotocin (STZ)-induced diabetic male rats was investigated. Methods: An experimental study was conducted on 45 adult male rats in 9 groups of 5 rats. The control group received normal food only. Other groups were made diabetic by injecting them with 60 mg/kg intraperitoneal STZ injection. Diabetic groups were: one Sham Group (STZ only), one Positive Diabetic Group (STZ + 0.5 ml normal saline) and 6 experimental groups, treated with STZ plus 3 incremental doses (30, 60 and 120 mg/kg) of either leaves or fruits extract of A. marina for three consecutive days, using gavage method. 24 hours after the last extract administration, blood samples were taken from the rat hearts., the serum glucose and insulin levels were measured by glucose oxidase and ELISA methods, respectively, one week after the STZ injections and following 8-12 hours of fasting. Results: The extract of leaves and fruits of A. marina in all doses significantly decreased the serum glucose in diabetic rats compared to that in the Sham group. The extract of A. marina leaves at 30 mg/kg significantly increased the serum insulin level compared to that in Diabetic Sham Group. The extract of A. marina fruits at all doses significantly increased the serum insulin level in the Experimental Groups compared to the Sham Group (P <0.05). Conclusion: The extract of leaves and fruits of A. marina significantly reduced the serum glucose in STZ-induced diabetic rats.

scholarly journals Effect of postmenopausal status on insulin sensitivity in myanmar women

2016 ◽  
Vol 7 (5) ◽  
pp. 36-41
Author(s):  
Lwin Aye Thet ◽  
Mya Thanda Sein ◽  
Tint Swe Latt
Keyword(s):  
Insulin Resistance ◽  
Blood Glucose ◽  
Insulin Sensitivity ◽  
Serum Insulin ◽  
Fasting Blood Glucose ◽  
Insulin Level ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Insulin Level ◽  
Fasting Serum ◽  
Postmenopausal Status

Background: Animal studies show that ovarian hormone deficiency is associated with development of insulin resistance. In women, the menopause transition marks the cessation of ovarian function and insulin sensitivity would be reduced in postmenopausal women.Aim and Objectives: This study aimed to evaluate the insulin sensitivity in Myanmar postmenopausal women compared to premenopausal womenMaterial and Methods: A cross sectional comparative study was undertaken in non obese, normal glucose tolerant post menopausal women (n=42, BMI (mean± SD) 21.3±2.8 kg/m2, age 52.6±4.4 years) and premenopausal women (n=33, BMI(mean± SD)  19.7±2.2 kg/m2, age32.7±4.9 years). Insulin sensitivity was assessed by homeostasis model assessment method of insulin resistance (HOMA-IR) based on fasting blood glucose and fasting serum insulin level. Blood glucose was determined by glucose oxidase method. Serum insulin was estimated by enzyme linked immunosorbent assay (ELISA).Results:No differences in fasting blood glucose level (Mean ±SD 4.87±0.51 vs. 4.76±0.63mmol/L), fasting serum insulin level [median and interquartile range (IQR) 8.1 (6.7-11.8) vs. 8.1(6.5-9.9)    µ IU/ml] and HOMA-IR [median and IQR 1.7 (1.4-2.8) vs. 1.7 (1.2-2.2)] were found between premenopausal and postmenopausal women.Conclusion: Postmenopausal status has no effect on insulin sensitivity in postmenopausal women.Asian Journal of Medical Sciences Vol.7(5) 2016 36-41

Evaluation and correlation among T2DM patient with and without micro and macrovascular changes with various biochemical parameters

2015 ◽  
Vol 5 (3) ◽  
pp. 107-113
Author(s):  
Poonam Tyagi
Keyword(s):  
Insulin Resistance ◽  
Biochemical Parameters ◽  
Hba1c Level ◽  
Serum Insulin ◽  
Insulin Level ◽  
Magnesium Level ◽  
Study Group ◽  
Serum Insulin Level ◽  
Group Iii ◽  
Group Ii

  Serum insulin level and insulin resistance are the prominent precursors of type 2 diabetes mellitus and HbA1c level correlates favorably with glycemic level. Obesity and dietary macronutrients also apparently play a role in this disease. Hence, insulin resistance, HbA1c, lipid profile and Magnesium level were evaluated in T2DM subjects categorized as having macro and micro-vascular complications and results were compared with controls. 200 sub-jects, grouped as- group I (50 normal healthy controls) ,Group- II (75 patients without any complication) and Group- III (75 patients having micro or macrovascular complications) were selected for this research study. We observed the fasting blood glucose level, serum HbA1c level, serum insulin level, insulin resistance, magnesium level and lipid profile in all group subjects. Significant increase in serum fasting glucose (p<0.001), insulin level (p<0.001) and re-sistance (p<0.001) was observed in both group II and Group III subjects when compared with control group. . HbA1c (%) level were recorded very high in both study group patients (p<0.01 and p<0.001). Serum magnesium level was measured and study group diabetic patients showed hypomagnesemia (p<0.01). Statistically highly significant value of Serum total cholesterol (p<0.001), triglyceride (pË‚ 0.01) and LDL-C (p<0.001) were observed in both group subjects when compared with controls. Whereas statistically signifi-cantly decreases in serum HDLC (p<0.001) level were evaluated. Significant correlation coefficient with determination among diabetic group II and III patients and various biochemical parameters were evaluated. Hypomagnesemia and a higher level of cholesterol and TG values are responsible for macro-vascular changes in T2-DM.

scholarly journals Endothelial dysfunction precedes hypertension in diet-induced insulin resistance

1998 ◽  
Vol 275 (3) ◽  
pp. R788-R792 ◽  
Author(s):  
Prasad V. G. Katakam ◽  
Michael R. Ujhelyi ◽  
Margarethe E. Hoenig ◽  
Allison Winecoff Miller
Keyword(s):  
Insulin Resistance ◽  
Endothelial Dysfunction ◽  
Serum Insulin ◽  
Serum Glucose ◽  
Mesenteric Arteries ◽  
Control Group ◽  
Sprague Dawley ◽  
Insulin Resistant ◽  
Glucose Levels

The insulin-resistant (IR) syndrome may be an impetus for the development of hypertension (HTN). Unfortunately, the mechanism by which this could occur is unclear. Our laboratory and others have described impaired endothelium-mediated relaxation in IR, mildly hypertensive rats. The purpose of the current study is to determine if HTN is most likely a cause or result of impaired endothelial function. Sprague-Dawley rats were randomized to receive a fructose-rich diet for 3, 7, 10, 14, 18, or 28 days or were placed in a control group. The control group received rat chow. After diet treatment, animals were instrumented with arterial cannulas, and while awake and unrestrained, their blood pressure (BP) was measured. Subsequently, endothelium-mediated relaxation to acetylcholine was determined (in vitro) by measuring intraluminal diameter of phenylephrine-preconstricted mesenteric arteries (∼250 μM). Serum insulin levels were significantly elevated in all groups receiving fructose feeding compared with control, whereas there were no differences in serum glucose levels between groups. Impairment of endothelium-mediated relaxation starts by day 14 [mean percent maximal relaxation (Emax): 69 ± 10% of baseline] and becomes significant by day 18 (Emax: 52 ± 11% of baseline; P < 0.01). However, the mean BP (mmHg) does not become significantly elevated until day 28 [BP: 132 ± 1 ( day 28) vs. 116 ± 3 (control); P < 0.05]. These findings demonstrate that both IR and endothelial dysfunction occur before HTN in this model and suggest that endothelial dysfunction may be a mechanism linking insulin resistance and essential HTN.

scholarly journals Serum Proinsulin in Bangladeshi Subjects with Impaired Glucose Tolerance

2015 ◽  
Vol 7 (2) ◽  
pp. 41-46
Author(s):  
S Sultana ◽  
Z Zeba ◽  
A Hossain ◽  
A Khaleque ◽  
R Zinnat ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Insulin Sensitivity ◽  
Glucose Tolerance ◽  
Serum Insulin ◽  
Serum Glucose ◽  
Glucose Load ◽  
Fasting Serum ◽  
Insulin Secretory Capacity ◽  
Proinsulin Level ◽  
Secretory Capacity

Hyperproinsulinemia is commonly present in subjects with impaired glucose tolerance. The present study was undertaken to investigate the proinsulin level in Bangladeshi IGT subjects and to explore its association with insulin resistance. This observational study was conducted under a case-control design with IGT subjects (n=50) and controls (n=44). IGT was diagnosed following the WHO Study Group Criteria. Serum glucose was measured by glucose-oxidase method, serum lipid profile by enzymatic method and serum insulin and serum proinsulin were measured by ELISA method. Insulin secretory capacity (HOMA%B) and insulin sensitivity (HOMA%S) were calculated from fasting serum glucose and fasting serum insulin by homeostasis model assessment. The study subjects were age- and BMI- matched. Mean (±SD) age (yrs) of the control and IGT subjects were 40±6 and 40±5 respectively (p=0.853). Mean (±SD) BMI of the control and IGT subjects were 23±3 and 22±2 respectively (p=0.123). Fasting glucose was not significantly higher in IGT subjects, but serum glucose 2 hours after 75 gm glucose load was significantly higher in IGT subjects. Median (Range) value of fasting serum glucose (mmol/l) of control and IGT subjects were 5.3 (3.8-6) and 5.2 (4-12) respectively; (p=0.297). Median (Range) value of serum glucose (mmol/l) 2 hours after 75 gm glucose load of control and IGT subjects were 6.1 (3-7.8) and 7.9 (5- 21) respectively; (p=0.001). Fasting TG was significantly higher in IGT subjects and LDL-c was significantly lower in IGT subjects. Serum Total cholesterol and HDL-c were not significantly different between the IGT and control subjects. Median (Range) value of fasting serum TG (mg/dl) of control and IGT subjects were 119 (51-474) and 178 (82-540) respectively; (p=0.001). Median (Range) value of fasting serum T chol (mg/dl) of control and IGT subjects were 180 (65-272) and 186 (140-400) respectively; (p=0.191). Median (Range) value of fasting serum HDL-C (mg/dl) of control and IGT subjects were 29 (19-45) and 31 (15-78) respectively; (p=0.914). Median (Range) value of fasting serum LDL-C (mg/dl) of control and IGT subjects were 117(29-201) and 111(41- 320) respectively; (p=0.001). Fasting serum proinsulin was significantly higher in IGT subjects. Median (Range) value of fasting serum proinsulin (pmol/l) of control and IGT subjects were 9.2(1.8-156) and 17(3-51) respectively; (p=0.001). Insulin secretory capacity (HOMA%B) was higher but insulin sensitivity (HOMA%S) was significantly lower in case of IGT subjects. Median (Range) value of HOMA%B of control and IGT subjects were 97(46-498) and 164(17-300) respectively; (p=0.001). Median (Range) value of HOMA%S of control and IGT subjects were 68(19-270) and 39(15-110) respectively (p=0.001). In multiple regression analysis a significant negative association was found between fasting proinsulin and insulin sensitivity (p=0.037). The data led to the following conclusions: a) Insulin resistance is the predominant defect in Bangladeshi IGT subjects. b) Basal proinsulin level is significantly increased in IGT subjects. c) Insulin resistance is negatively associated with serum proinsulin in IGT subjects. DOI: http://dx.doi.org/10.3329/bjmb.v7i2.22411 Bangladesh J Med Biochem 2014; 7(2): 41-46

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