scholarly journals Redox Status and Neuro Inflammation Indexes in Cerebellum and Motor Cortex of Wistar Rats Supplemented with Natural Sources of Omega-3 Fatty Acids and Astaxanthin: Fish Oil, Krill Oil, and Algal Biomass

Marine Drugs ◽  
2015 ◽  
Vol 13 (10) ◽  
pp. 6117-6137 ◽  
Author(s):  
Tatiana Polotow ◽  
Sandra Poppe ◽  
Cristina Vardaris ◽  
Douglas Ganini ◽  
Maísa Guariroba ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Motor Cortex ◽  
Algal Biomass ◽  
Wistar Rats ◽  
Redox Status ◽  
Omega 3 Fatty Acids ◽  
Krill Oil ◽  
Omega 3 ◽  
Natural Sources ◽  
Neuro Inflammation

Comparative study of tissue deposition of omega-3 fatty acids from polar-lipid rich oil of the microalgae Nannochloropsis oculata with krill oil in rats

2015 ◽  
Vol 6 (1) ◽  
pp. 185-191 ◽  
Author(s):  
Michael L. Kagan ◽  
Aharon Levy ◽  
Alicia Leikin-Frenkel
Keyword(s):  
Fatty Acids ◽  
Comparative Study ◽  
Polar Lipid ◽  
Rat Plasma ◽  
Nannochloropsis Oculata ◽  
Polar Lipids ◽  
Omega 3 Fatty Acids ◽  
Krill Oil ◽  
Omega 3 ◽  
Epa And Dha

An oil from micro-algae rich in EPA with no DHA and consisting of 15% polar lipids (phospholipids and glycolipids) showed equivalent uptake of EPA into rat plasma and organs as omega-3 krill oil consisting of EPA and DHA and 40% phospholipids.

Omega-3 fatty acids moderate oxidative and proinflammatory events in experimental hepatotoxicity in Wistar rats: comparison with livolin

Synergy ◽  
2018 ◽  
Vol 7 ◽  
pp. 17-24 ◽  
Author(s):  
Luqman Aribidesi Olayaki ◽  
Wale Johnson Adeyemi ◽  
Joseph Sunday Yinusa ◽  
Grace Amarachi Adedayo
Keyword(s):  
Fatty Acids ◽  
Wistar Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Omega-3 Fatty Acids Inhibit Tumor Growth in a Rat Model of Bladder Cancer

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Belmiro Parada ◽  
Flávio Reis ◽  
Raquel Cerejo ◽  
Patrícia Garrido ◽  
José Sereno ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Bladder Cancer ◽  
Rat Model ◽  
Redox Status ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Markers Of Inflammation ◽  
Male Wistar Rats ◽  
Serum Crp

Omega-3 (ω-3) fatty acids have been tested on prevention and treatment of several cancer types, but the efficacy on “in vivo” bladder cancer has not been analyzed yet. This study aimed at evaluating the chemopreventive efficacy of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) mixture in an animal model of bladder cancer. Forty-four male Wistar rats were divided into 4 groups during a 20-week protocol: control; carcinogen—N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN);ω-3 (DHA + EPA); andω-3 + BBN. BBN andω-3 were given during the initial 8 weeks. At week 20 blood and bladder were collected and checked for the presence of urothelium lesions and tumors, markers of inflammation, proliferation, and redox status. Incidence of bladder carcinoma was, control (0%),ω-3 (0%), BBN (65%), andω-3 + BBN (62.5%). Theω-3 + BBN group had no infiltrative tumors or carcinomain situ, and tumor volume was significantly reduced compared to the BBN (0.9 ± 0.1 mm3versus 112.5 ± 6.4 mm3). Also, it showed a reduced MDA/TAS ratio and BBN-induced serum CRP, TGF-β1, and CD31 were prevented. In conclusion, omega-3 fatty acids inhibit the development of premalignant and malignant lesions in a rat model of bladder cancer, which might be due to anti-inflammatory, antioxidant, anti-proliferative, and anti-angiogenic properties.

scholarly journals Evaluation of liver regeneration diet supplemented with omega-3 fatty acids: experimental study in rats

2015 ◽  
Vol 42 (6) ◽  
pp. 393-397 ◽  
Author(s):  
Rosilda Mendes da Silva ◽  
Osvaldo Malafaia ◽  
Orlando Jorge Martins Torres ◽  
Nicolau Gregori Czeczko ◽  
Carlos Hespanha Marinho Junior ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Liver Regeneration ◽  
Wistar Rats ◽  
Statistical Difference ◽  
Histological Study ◽  
Liver Weight ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Serum Aspartate Aminotransferase ◽  
Significant Interference

Objective: to evaluate liver regeneration in rats after partial hepatectomy of 60% with and without action diet supplemented with fatty acids through the study of the regenerated liver weight, laboratory parameters of liver function and histological study. Methods: thirty-six Wistar rats, males, adults were used, weighing between 195 and 330 g assigned to control and groups. The supplementation group received the diet by gavage and were killed after 24h, 72h and seven days. Evaluation of regeneration occurred through analysis of weight gain liver, serum aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltranspeptidase, and mitosis of the liver stained with H&E. Results: the diet supplemented group showed no statistical difference (p>0.05) on the evolution of weights. Administration of fatty acids post-hepatectomy had significant reduction in gamma glutamyltransferase levels and may reflect liver regeneration. Referring to mitotic index, it did not differ between period of times among the groups. Conclusion: supplementation with fatty acids in rats undergoing 60% hepatic resection showed no significant interference related to liver regeneration.

scholarly journals Lower Omega-3 Index Is a Marker of Increased Propensity of Hypertensive Rat Heart to Malignant Arrhythmias

2013 ◽  
pp. S201-S208 ◽  
Author(s):  
B. BAČOVÁ ◽  
P. SEČ ◽  
J. RADOŠINSKÁ ◽  
M. ČERTÍK ◽  
A. VACHULOVÁ ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Rat Heart ◽  
Wistar Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Pufa Intake ◽  
Spontaneously Hypertensive ◽  
Hypertensive Rat ◽  
Total Fatty Acids ◽  
Malignant Arrhythmias

Polyunsaturated omega-3 fatty acids (ω-3 PUFA) are important components of cell membrane affecting its function and their deficiency is deleterious to health. We have previously shown that spontaneously hypertensive rats (SHR) are prone to lifethreatening arrhythmias that are reduced by ω-3 PUFA intake. Purpose of this study was to explore plasma and red blood cells (RBC) profile of ω-3 and ω-6 PUFA as well as to determine ω-3 index, a risk factor for sudden cardiac death, in aged SHR and the effect of ω-3 PUFA intake. Male and female 12-month-old SHR and age-matched Wistar rats fed with ω-3 PUFA (200 mg/kg BW/day/2 month) were compared with untreated rats. Composition of ω-3 PUFA: alfa linolenic acid, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) as well as ω-6 PUFA: linoleic acid and arachidonic acid was analyzed by gas chromatography. Results showed sex- and strain-related differences of basal ω-3 and ω-6 PUFA levels in plasma and RBC as well as in response to ω-3 PUFA intake. Comparing to Wistar rats ω-3 index, expressed as a percentage of EPA+DHA of total fatty acids, was lower in SHR and it increased due to consumption of ω-3 PUFA. Findings support our hypothesis that lower ω-3 index may be also a marker of increased propensity of the hypertensive rat heart to malignant arrhythmias.

Physical and oxidation stability of self-emulsifying krill oil-in-water emulsions

2016 ◽  
Vol 7 (8) ◽  
pp. 3590-3598 ◽  
Author(s):  
Qian Wu ◽  
Sibel Uluata ◽  
Leqi Cui ◽  
Chao Wang ◽  
Dongsheng Li ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Oxidation Stability ◽  
Omega 3 Fatty Acids ◽  
Krill Oil ◽  
Omega 3 ◽  
Oil In Water ◽  
Unique Source

Krill oil is a unique source of omega-3 fatty acids since it is a mixture of phospholipids and triacylglycerols.

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