scholarly journals Potential of Beetroot and Blackcurrant Compounds to Improve Metabolic Syndrome Risk Factors

Metabolites ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 338
Author(s):  
Cameron Haswell ◽  
Ajmol Ali ◽  
Rachel Page ◽  
Roger Hurst ◽  
Kay Rutherfurd-Markwick

Metabolic syndrome (MetS) is a group of metabolic abnormalities, which together lead to increased risk of coronary heart disease (CHD) and type 2 diabetes mellitus (T2DM), as well as reduced quality of life. Dietary nitrate, betalains and anthocyanins may improve risk factors for MetS and reduce the risk of development of CHD and T2DM. Beetroot is a rich source of dietary nitrate, and anthocyanins are present in high concentrations in blackcurrants. This narrative review considers the efficacy of beetroot and blackcurrant compounds as potential agents to improve MetS risk factors, which could lead to decreased risk of CHD and T2DM. Further research is needed to establish the mechanisms through which these outcomes may occur, and chronic supplementation studies in humans may corroborate promising findings from animal models and acute human trials.

2016 ◽  
Vol 88 (10) ◽  
pp. 93-98 ◽  
Author(s):  
I A Sadulaeva ◽  
Yu A Vasyuk ◽  
O S Trofimenko ◽  
E N Yushchuk ◽  
S V Ivanova ◽  
...  

The presence of metabolic syndrome (MS) in a patient allows him to be assigned to a group at high risk for atherosclerosis, cardiovascular events, coronary heart disease, and type 2 diabetes mellitus. In addition, MS negatively affects not only the heart and vessels, but also kidney function, which leads to chronic kidney disease (CKD). MS is pathogenetically associated with CKD and is an independent prognostic factor of the development of the latter, namely, the involvement of the kidney frequently determines prognosis and quality of life in these patients. The paper gives a modern view on the concept of MS and CKD and considers its main diagnostic criteria, etiology, and pathogenesis. The study of the relationships between MS and CKD may suggest that the high prevalence of kidney dysfunction in the general population is largely determined by metabolic nephropathies, including obesity-related nephropathy. The identification of risk factors and poor prognostic markers in this category of patients seems to be extremely important for the early diagnosis of the disease and their timely elimination is one of the main approaches to the comprehensive prevention of CKD in these patients.


2021 ◽  
pp. jrheum.210963
Author(s):  
Ying-Ying Leung

Psoriatic arthritis (PsA) is a systemic inflammatory disease affecting domains beyond the musculoskeletal system, and may lead to disability and impaired quality of life. It is associated with comorbidities such as hypertension, diabetes mellitus, obesity, metabolic syndrome, and increased risk of cardiovascular events.


Duazary ◽  
2019 ◽  
Vol 16 (3) ◽  
pp. 25-39
Author(s):  
Yenny Alexandra Granados-Vidal ◽  
Sandra Jimena Jácome-Velasco ◽  
Aura Paternina-De la Ossa ◽  
Brigid Galvis-Fernández ◽  
Andres Villaquiran-Hurtado

 The objective of the study was to determine the lifestyle and quality of life in type 2 diabetes mellitus and metabolic syndrome patients in the city of Popayán. A descriptive cross-sectional study was carried out with 81 patients with metabolic syndrome and type 2 diabetes mellitus diagnoses. EUROQOL questionnaires of 5 Dimensions-3 Levels were applied, as well as the IMEVID test, in order to evaluate the quality of life and lifestyle of each group of patients. Anthropometric measures were also taken, such as Body Mass Index, Waist-Hip Ratio and skinfolds. Regarding the results, 33.33% of the participants were between 61 and 70 years of age 56.8% presented moderate pain problems/discomfort, 61.7% presented an unhealthy lifestyle and obtained variable relationships such as: waist-hip ratio - glycemia (p = 0.021, r = -0.257), body density - triglycerides (p = 0.018, r = 0.263), age and mobility EUROQOL (p = 0.001, r = 0.350). In conclusion, lifestyle changes are one of the pillars to control metabolic syndrome and type 2 diabetes mellitus. Evaluating the quality of life also makes it possible to understand how compromised patients’ abilities are, in order to create relevant strategies and actions that seek their well-being.


2018 ◽  
Vol 72 (4_Supplement_1) ◽  
pp. 7211515292p1
Author(s):  
Arlene Schmid ◽  
Matthew P. Malcolm ◽  
Karen E. Atler ◽  
Laura A. Grimm ◽  
Tara Klinedinst ◽  
...  

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