scholarly journals Optimization of Extraction or Purification Process of Multiple Components from Natural Products: Entropy Weight Method Combined with Plackett–Burman Design and Central Composite Design

Molecules ◽  
2021 ◽  
Vol 26 (18) ◽  
pp. 5572
Author(s):  
Yu Du ◽  
Pengcheng Huang ◽  
Weifeng Jin ◽  
Chang Li ◽  
Jiehong Yang ◽  
...  

In this paper, the optimization of the extraction/purification process of multiple components was performed by the entropy weight method (EWM) combined with Plackett–Burman design (PBD) and central composite design (CCD). We took the macroporous resin purification of Astragalus saponins as an example to discuss the practicability of this method. Firstly, the weight of each component was given by EWM and the sum of the product between the componential content and its weight was defined as the comprehensive score, which was taken as the evaluation index. Then, the single factor method was adopted for determining the value range of each factor. PBD was applied for screening the significant factors. Important variables were further optimized by CCD to determine the optimal process parameters. After the combination of EWM, PBD and CCD, the resulting optimal purification conditions were as follows: pH value of 6.0, the extraction solvent concentration of 0.15 g/mL, and the ethanol volume fraction of 75%. Under the optimal conditions, the practical comprehensive score of recoveries of saponins was close to the predicted value (n = 3). Therefore, the present study provided a convenient and efficient method for extraction and purification optimization technology of multiple components from natural products.

Author(s):  
Quanle Zou ◽  
Tiancheng Zhang ◽  
Wei Liu

In recent years, various large- and medium-sized shopping malls have been essential components of each city with the speed-up of China’s urbanization process and the improvement of residents’ living standard. A method for evaluating fire risk in shopping malls based on quantified safety checklist and structure entropy weight method was proposed according to related literatures as well as laws and regulations by analyzing the characteristics of fires occurring in shopping malls in recent years. At first, the factors influencing the fire risk in shopping malls were determined by carrying out on-site survey and visiting related organizations to construct an evaluation index system for fires occurring in shopping malls; afterwards, a quantified safety checklist composed of four parts (i.e. safety grade, grade description, scoring criterion and index quantification) was established based on related laws and regulations; subsequently, index weights were determined by utilizing structure entropy weight method, thus putting forward a method for assessing fire risk in shopping malls based on quantified safety checklist and structure entropy weight method. Eventually, the applicability of the evaluation method was validated exampled by Wal-Mart. The research result provides a theoretical basis for further improvement of the theoretical system for fire risk evaluation in shopping malls, and also exerts practical and guidance significance on timeous and effective early warning as well as prevention and control of building fires.


2011 ◽  
Vol 347-353 ◽  
pp. 1735-1739
Author(s):  
Jie Shang ◽  
Yuan Yao

This paper has analyzed the degree of agricultural waste recycling utilization, and problems existing in current rural calculated degree of waste recycling in Heilongjiang province, using AHP and entropy weight method integrated and construct the rural waste recycling system, and points out that the evaluation index system of agricultural waste recycling after the development direction.,This paper has analyzed the degree of agricultural waste recycling utilization, and problems existing in current rural calculated degree of waste recycling in Heilongjiang province, using AHP and entropy weight method integrated and construct the rural waste recycling system, and points out that the evaluation index system of agricultural waste recycling after the development direction.


2011 ◽  
Vol 50-51 ◽  
pp. 756-760
Author(s):  
Bao Feng Li ◽  
Jing Guo Qu ◽  
Pu Yu Hao

In this paper, using the relevant data of 34 teaching staffs who participate in the academic title evaluation of associate professor in 2010, firstly it introduces the entropy weight method, Topsis method with subjective weight, Topsis method with objective weight and double base points method with subjective weight to evaluate and sort the performance of 34 teaching staffs. Secondly, two combination evaluation models are constructed to do the same work and the conclusions are more science and rational.


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