scholarly journals Roles of Chitosan in Green Synthesis of Metal Nanoparticles for Biomedical Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 273
Author(s):  
Thi Tuong Vy Phan ◽  
Duc Tri Phan ◽  
Xuan Thang Cao ◽  
Thanh-Canh Huynh ◽  
Junghwan Oh
Keyword(s):  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Future Development ◽  
Biomedical Engineering ◽  
Biomedical Applications ◽  
Comprehensive Overview ◽  
The Future ◽  
Size Controlling

Chitosan (CS) is a well-known stabilizer for metal nanoparticles in biomedical engineering. However, very few studies have explored other important roles of CS including reducing, shape-directing, and size-controlling. This review aims to provide the latest and most comprehensive overview of the roles of CS in the green synthesis of metal nanoparticles for biomedical applications. To the best of our knowledge, this is the first review that highlights these potentialities of CS. At first, a brief overview of the properties and the bioactivity of CS is presented. Next, the benefits of CS for enhancing the physicochemical behaviors of metal nanoparticles are discussed in detail. The representative biomedical applications of CS-metal nanoparticles are also given. Lastly, the review outlines the perceptual vision for the future development of CS-metal nanoparticles in the biomedicine field.

Review on Methodologies Used in the Synthesis of Metal Nanoparticles: Significance of Phytosynthesis Using Plant Extract as an Emerging Tool

2020 ◽  
Vol 26 (40) ◽  
pp. 5188-5204
Author(s):  
Uzair Nagra ◽  
Maryam Shabbir ◽  
Muhammad Zaman ◽  
Asif Mahmood ◽  
Kashif Barkat
Keyword(s):  
Green Synthesis ◽  
Metal Nanoparticles ◽  
Plant Extracts ◽  
Biomedical Applications ◽  
Noble Metals ◽  
Cost Effective ◽  
Green Technology ◽  
Critical Parameters ◽  
Nanosized Particles ◽  
Preparation Methods

Nanosized particles, with a size of less than 100 nm, have a wide variety of applications in various fields of nanotechnology and biotechnology, especially in the pharmaceutical industry. Metal nanoparticles [MNPs] have been synthesized by different chemical and physical procedures. Still, the biological approach or green synthesis [phytosynthesis] is considered as a preferred method due to eco-friendliness, nontoxicity, and cost-effective production. Various plants and plant extracts have been used for the green synthesis of MNPs, including biofabrication of noble metals, metal oxides, and bimetallic combinations. Biomolecules and metabolites present in plant extracts cause the reduction of metal ions into nanosized particles by one-step preparation methods. MNPs have remarkable attractiveness in biomedical applications for their use as potential antioxidant, anticancer and antibacterial agents. The present review offers a comprehensive aspect of MNPs production via top-to-bottom and bottom-to-top approach with considerable emphasis on green technology and their possible biomedical applications. The critical parameters governing the MNPs formation by plant-based synthesis are also highlighted in this review.

scholarly journals Synthesis, Bioapplications, and Toxicity Evaluation of Chitosan-Based Nanoparticles

2019 ◽  
Vol 20 (22) ◽  
pp. 5776 ◽  
Author(s):  
Balsam R. Rizeq ◽  
Nadin N. Younes ◽  
Kashif Rasool ◽  
Gheyath K. Nasrallah
Keyword(s):  
Biomedical Engineering ◽  
Biomedical Applications ◽  
Chitosan Nanoparticles ◽  
Nanoparticle Synthesis ◽  
Physicochemical Characteristics ◽  
Mitigation Strategies ◽  
Comprehensive Overview ◽  
Future Directions ◽  
Bactericidal Properties

The development of advanced nanomaterials and technologies is essential in biomedical engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront and attract wide interest due to their versatile physicochemical characteristics such as biodegradability, biocompatibility, and non-toxicity, which play a promising role in biological applications. Chitosan and its derivatives are employed in several applications including pharmaceuticals and biomedical engineering. This article presents a comprehensive overview of recent advances in chitosan derivatives and nanoparticle synthesis, as well as emerging applications in medicine, tissue engineering, drug delivery, gene therapy, and cancer therapy. In addition to the applications, we critically review the main concerns and mitigation strategies related to chitosan bactericidal properties, toxicity/safety using tissue cultures and animal models, and also their potential environmental impact. At the end of this review, we also provide some of future directions and conclusions that are important for expanding the field of biomedical applications of the chitosan nanoparticles.

Obecny stan badań nad Zagładą na Ukrainie

2014 ◽  
pp. 889-915
Author(s):  
Anna Abakunkova
Keyword(s):  
Future Development ◽  
The State ◽  
Significant Part ◽  
Educational Organizations ◽  
Major Research ◽  
Holocaust Studies ◽  
The Holocaust ◽  
The Future

The article examines the state of the Holocaust historiography in Ukraine for the period of 2010 – beginning of 2014. The review analyzes activities of major research and educational organizations in Ukraine which have significant part of projects devoted to the Holocaust; main publications and discussions on the Holocaust in Ukraine, including publications of Ukrainian authors in academic European and American journals. The article illustrates contemporary tendencies and conditions of the Holocaust Studies in Ukraine, defines major problems and shows perspectives of the future development of the Holocaust historiography in Ukraine.

Remedies for Breach of Contract: The Future Development of Scots Law in its European and International Context

1997 ◽  
Vol 1 (2) ◽  
pp. 200-226 ◽  
Author(s):  
Hector L MacQueen
Keyword(s):  
Future Development ◽  
European Contract ◽  
Breach Of Contract ◽  
International Context ◽  
The United Kingdom ◽  
Current State ◽  
The Future ◽  
University Of Edinburgh ◽  
International Conventions ◽  
Law Commission

This paper,first presented on 21 October 1995 at ajoint seminar ofthe Scottish Law Commission and the Faculty of Law, University of Edinburgh, on the subject of breach of contract, considers the future development of the law in this area, first by considering its history and current state in comparative terms and drawing the conclusion that it is characterised by a mixture of Civilian and Common Law elements; second, by comparing Scots law with the provisions on breach contained in recently published proposals for a harmonised law of contract (the UNIDROIT Principles of International Commercial Contracts, the Principles of European Contract Law prepared by the Lando Commission, and the draft “code”for the United Kingdom prepared on behalf of the English Law Commission by Harvey McGregor in the late 1960s) and in international conventions on the sale of goods. Although Scots law emerges reasonably wellfrom this exercise, there are a number of points to be taken on board in any future reform, as well as some insights into important underlying principles.

Future Development Strategies for KODISA Journals : Overview of 2017 and Strategic Plans for the Future

2018 ◽  
Vol 16 (5) ◽  
pp. 83-90 ◽  
Author(s):  
Hee-Joong Hwang ◽  
Jung Wan Lee ◽  
Dong-Ho Kim ◽  
Jong-Ho Lee ◽  
Byung-Goo Kim ◽  
...  
Keyword(s):  
Future Development ◽  
Development Strategies ◽  
Strategic Plans ◽  
The Future

Short Protecting Group-free Syntheses of CDE Synthon of Racemic Camptothecin

2020 ◽  
Vol 17 (7) ◽  
pp. 588-591
Author(s):  
Pingxuan Shao ◽  
Wei Lu ◽  
Lei Wang
Keyword(s):  
Total Synthesis ◽  
Future Development ◽  
Protecting Group ◽  
Short Route ◽  
The Future ◽  
Tricyclic Ketone

A practical and concise total synthesis of tricyclic ketone 7 (CDE ring), a valuable intermediate for the synthesis of racemic camptothecin and analogs, was described (8 chemical steps and 29% overall yield). The synthesis starts with two inexpensive, readily available materials and is operationally simple to perform. It is worth mentioning that the reported protecting group-free synthesis, with advantages of a short route, would be helpful for the future development of industry-scale syntheses of camptothecin-family alkaloids.

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