Fabrication of Polymer Composite Fibers Embedding Ultra-Long Micro/Nanowires

Fabrication of polymer composite fibers embedding ultra-long micro/nanowires via an iterative melt co-drawing and bundling technique is reported in this study. The poly(methyl methacrylate) (PMMA) porous array templates were prepared with section-cutting the PMMA/polystyrene (PS) (shell/core) composite fibers and dissolution of inner PS. The results showed that the PS cores or pores in the PMMA matrix are regularly arranged with hexagonal, and their diameter and spacing exhibits a uniform distribution. Especially, the core diameter can be precisely controlled from millimeter-scale to nanometer-scale by multi-step melt co-drawing. Based on the PMMA porous array templates, the Cu nanowires were successfully prepared by electrochemical deposition. Moreover, to fabricate PMMA ultra-long micro/nanowires, the composite fibers with converse shell/core component of PS/PMMA were initially prepared, and then the outer PS was dissolved. The obtained PMMA micro/nanowires were characterized with smooth complete orientation structure. The study provides an experimental basis for fabricating such polymer composite fibers, micro/nano porous array templates, and micro/nanowires with precise and controllable manner to meet the real application requirements.

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Magnetic Properties of Fe3O4/CoFe2O4 Composite Nanoparticles with Core/Shell Architecture

Ukrainian Journal of Physics ◽

10.15407/ujpe65.10.904 ◽

2020 ◽

Vol 65 (10) ◽

pp. 904

Author(s):

V. O. Zamorskyi ◽

Ya. M. Lytvynenko ◽

A. M. Pogorily ◽

A. I. Tovstolytkin ◽

S. O. Solopan ◽

...

Keyword(s):

Magnetic Properties ◽

Spinel Ferrite ◽

Composite Nanoparticles ◽

Core Shell ◽

Cofe2o4 Nanoparticles ◽

Core Diameter ◽

The Core ◽

Shell Particles ◽

Interface Parameters ◽

Shell Composite

Magnetic properties of the sets of Fe3O4(core)/CoFe2O4(shell) composite nanoparticles with a core diameter of about 6.3 nm and various shell thicknesses (0, 1.0, and 2.5 nm), as well as the mixtures of Fe3O4 and CoFe2O4 nanoparticles taken in the ratios corresponding to the core/shell material contents in the former case, have been studied. The results of magnetic research showed that the coating of magnetic nanoparticles with a shell gives rise to the appearance of two simultaneous effects: the modification of the core/shell interface parameters and the parameter change in both the nanoparticle’s core and shell themselves. As a result, the core/shell particles acquire new characteristics that are inherent neither to Fe3O4 nor to CoFe2O4. The obtained results open the way to the optimization and adaptation of the parameters of the core/shell spinel-ferrite-based nanoparticles for their application in various technological and biomedical domains.

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Geometrical Scaling of Antiresonant Hollow-Core Fibers for Mid-Infrared Beam Delivery

Crystals ◽

10.3390/cryst11040420 ◽

2021 ◽

Vol 11 (4) ◽

pp. 420

Author(s):

Ang Deng ◽

Wonkeun Chang

Keyword(s):

Structural Parameters ◽

Transmission Band ◽

Confinement Loss ◽

Hollow Core ◽

Core Size ◽

Core Diameter ◽

Mid Infrared ◽

The Core ◽

Tubular Type ◽

Beam Delivery

We numerically investigate the effect of scaling two key structural parameters in antiresonant hollow-core fibers—dielectric wall thickness of the cladding elements and core size—in view of low-loss mid-infrared beam delivery. We demonstrate that there exists an additional resonance-like loss peak in the long-wavelength limit of the first transmission band in antiresonant hollow-core fibers. We also find that the confinement loss in tubular-type hollow-core fibers depends strongly on the core size, where the degree of the dependence varies with the cladding tube size. The loss scales with the core diameter to the power of approximately −5.4 for commonly used tubular-type hollow-core fiber designs.

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Avolition as the core negative symptom in schizophrenia: relevance to pharmacological treatment development

npj Schizophrenia ◽

10.1038/s41537-021-00145-4 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Gregory P. Strauss ◽

Lisa A. Bartolomeo ◽

Philip D. Harvey

Keyword(s):

Negative Symptom ◽

Negative Symptoms ◽

Clinical Trial Design ◽

Core Component ◽

Treatment Target ◽

Global Improvement ◽

Treatment Development ◽

The Core ◽

Current Review ◽

Symptom Domains

AbstractNegative symptoms have long been considered a core component of schizophrenia. Modern conceptualizations of the structure of negative symptoms posit that there are at least two broad dimensions (motivation and pleasure and diminished expression) or perhaps five separable domains (avolition, anhedonia, asociality, blunted affect, alogia). The current review synthesizes a body of emerging research indicating that avolition may have a special place among these dimensions, as it is generally associated with poorer outcomes and may have distinct neurobiological mechanisms. Network analytic findings also indicate that avolition is highly central and interconnected with the other negative symptom domains in schizophrenia, and successfully remediating avolition results in global improvement in the entire constellation of negative symptoms. Avolition may therefore reflect the most critical treatment target within the negative symptom construct. Implications for targeted treatment development and clinical trial design are discussed.

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Lin28, a major translation reprogramming factor, gains access to YB-1-packaged mRNA through its cold-shock domain

Communications Biology ◽

10.1038/s42003-021-01862-3 ◽

2021 ◽

Vol 4 (1) ◽

Author(s):

Anastasiia Samsonova ◽

Krystel El Hage ◽

Bénédicte Desforges ◽

Vandana Joshi ◽

Marie-Jeanne Clément ◽

...

Keyword(s):

Cancer Progression ◽

Cold Shock ◽

Rna Binding ◽

Rna Binding Proteins ◽

Rna Binding Protein ◽

Large Set ◽

Core Component ◽

The Core ◽

Cold Shock Domain ◽

Global Translation

AbstractThe RNA-binding protein Lin28 (Lin28a) is an important pluripotency factor that reprograms translation and promotes cancer progression. Although Lin28 blocks let-7 microRNA maturation, Lin28 also binds to a large set of cytoplasmic mRNAs directly. However, how Lin28 regulates the processing of many mRNAs to reprogram global translation remains unknown. We show here, using a structural and cellular approach, a mixing of Lin28 with YB-1 (YBX1) in the presence of mRNA owing to their cold-shock domain, a conserved β-barrel structure that binds to ssRNA cooperatively. In contrast, the other RNA binding-proteins without cold-shock domains tested, HuR, G3BP-1, FUS and LARP-6, did not mix with YB-1. Given that YB-1 is the core component of dormant mRNPs, a model in which Lin28 gains access to mRNPs through its co-association with YB-1 to mRNA may provide a means for Lin28 to reprogram translation. We anticipate that the translational plasticity provided by mRNPs may contribute to Lin28 functions in development and adaptation of cancer cells to an adverse environment.

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Enhancing Postgraduate Learning and Teaching: Postgraduate Summer School in Dairy Science

Veterinary Medicine International ◽

10.1155/2014/409549 ◽

2014 ◽

Vol 2014 ◽

pp. 1-7 ◽

Cited By ~ 1

Author(s):

Pietro Celi ◽

Gianfranco Gabai ◽

Massimo Morgante ◽

Luigi Gallo

Keyword(s):

Summer School ◽

Research Collaboration ◽

Learning Experience ◽

Scientific Investigation ◽

Core Component ◽

Learning And Teaching ◽

Transferable Skills ◽

The Core ◽

Dairy Science ◽

The University

Dairy science is a multidisciplinary area of scientific investigation and Ph.D. students aiming to do research in the field of animal and/or veterinary sciences must be aware of this. Ph.D. students often have vast spectra of research interests, and it is quite challenging to satisfy the expectation of all of them. The aim of this study was to establish an international Ph.D. training program based on research collaboration between the University of Sydney and the University of Padova. The core component of this program was a two-week Postgraduate Summer School in Dairy Science, which was held at the University of Padova, for Ph.D. students of both universities. Therefore, we designed a program that encompassed seminars, workshops, laboratory practical sessions, and farm visits. Participants were surveyed using a written questionnaire. Overall, participants have uniformly praised the Summer School calling it a rewarding and valuable learning experience. The Ph.D. Summer School in Dairy Science provided its participants a positive learning experience, provided them the opportunity to establish an international network, and facilitated the development of transferable skills.

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Chapter II. The Prohibition of Attacks Directed at Civilians or Civilian Objects and of Disproportionate Attacks as the Core Component of the Principle of Distinction in the Conduct of Hostilities in International Humanitarian Law

Unlawful Attacks in Combat Situations ◽

10.1163/ej.9789004162006.i-292.7 ◽

2008 ◽

pp. 13-23

Keyword(s):

International Humanitarian Law ◽

Humanitarian Law ◽

Core Component ◽

The Core

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Architectural Design of Trusted Platform for IaaS Cloud Computing

International Journal of Cloud Applications and Computing ◽

10.4018/ijcac.2018040103 ◽

2018 ◽

Vol 8 (2) ◽

pp. 47-65 ◽

Cited By ~ 4

Author(s):

Ubaidullah Alias Kashif ◽

Zulfiqar Ali Memon ◽

Shafaq Siddiqui ◽

Abdul Rasheed Balouch ◽

Rakhi Batra

Keyword(s):

Cloud Computing ◽

Service Provider ◽

Architectural Design ◽

Cloud Services ◽

Core Component ◽

Malicious Activity ◽

The Core ◽

Potential Benefits ◽

Trusted Platform ◽

Access Right

This article describes how the enormous potential benefits provided by the cloud services, made enterprises to show huge interest in adopting cloud computing. As the service provider has control over the entire data of an organization stored onto the cloud, a malicious activity, whether internal or external can tamper with the data and computation. This causes enterprises to lack trust in adopting services due to privacy, security and trust issues. Despite of having such issues, the consumer has no root level access right to secure and check the integrity of procured resources. To establish a trust between the consumer and the provider, it is desirable to let the consumer to check the procured platform hosted at provider side for safety and security. This article proposes an architectural design of a trusted platform for the IaaS cloud computing by the means of which the consumer can check the integrity of a guest platform. TCG's TPM is deployed and used on the consumer side as the core component of the proposed architecture and it is distributed between the service provider and the consumer.

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Determination of all Dimensions of CdSe Seeded CdS Nanorods Solely via their UV/Vis Spectra

Zeitschrift für Physikalische Chemie ◽

10.1515/zpch-2016-0887 ◽

2017 ◽

Vol 231 (1) ◽

Cited By ~ 4

Author(s):

Patrick Adel ◽

Julian Bloh ◽

Dominik Hinrichs ◽

Torben Kodanek ◽

Dirk Dorfs

Keyword(s):

Absorption Spectra ◽

Extinction Coefficient ◽

Core Diameter ◽

The Core ◽

Extinction Spectra ◽

Cds Nanorods ◽

Fast Route ◽

Characteristic Points ◽

Electron Microscopical

AbstractIn the present manuscript we develop a method to determine all characteristic dimensions of CdSe seeded CdS nanorods solely via their extinction spectra without the need for electron microscopical investigations. In detail, the core diameter as well as the overall diameter and length and the molar extinction coefficient can all be derived from characteristic points in the absorption spectra. We carefully investigate in which size regime our assumptions are valid and give an estimation of the expected error, making it possible for the reader to decide whether this method is sufficiently accurate for their respective system. Our method displays a comfortable and fast route to analyze these nowadays often used nanorods.

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Mitochondria-driven assembly of a cortical anchor for mitochondria and dynein

The Journal of Cell Biology ◽

10.1083/jcb.201702022 ◽

2017 ◽

Vol 216 (10) ◽

pp. 3061-3071 ◽

Cited By ~ 22

Author(s):

Lauren M. Kraft ◽

Laura L. Lackner

Keyword(s):

Plasma Membrane ◽

Mitotic Spindle ◽

Cell Cortex ◽

Dual Function ◽

Mitochondrial Inheritance ◽

Cellular Functions ◽

Core Component ◽

Spindle Positioning ◽

The Core ◽

Contact Sites

Interorganelle contacts facilitate communication between organelles and impact fundamental cellular functions. In this study, we examine the assembly of the MECA (mitochondria–endoplasmic reticulum [ER]–cortex anchor), which tethers mitochondria to the ER and plasma membrane. We find that the assembly of Num1, the core component of MECA, requires mitochondria. Once assembled, Num1 clusters persistently anchor mitochondria to the cell cortex. Num1 clusters also function to anchor dynein to the plasma membrane, where dynein captures and walks along astral microtubules to help orient the mitotic spindle. We find that dynein is anchored by Num1 clusters that have been assembled by mitochondria. When mitochondrial inheritance is inhibited, Num1 clusters are not assembled in the bud, and defects in dynein-mediated spindle positioning are observed. The mitochondria-dependent assembly of a dual-function cortical anchor provides a mechanism to integrate the positioning and inheritance of the two essential organelles and expands the function of organelle contact sites.

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