Marble Waste Sludges as Effective Nanomaterials for Cu (II) Adsorption in Aqueous Media

This study evaluated the waste generated by a Spanish marble-producing company as adsorbent for the removal of copper (Cu [II]) from aqueous media. Six marble waste sludge samples were studied, and the following operational parameters were analyzed in discontinuous regime, including pollutant concentration, pH, temperature, nature of aqueous medium, and ionic strength. The applicability of the adsorbent material was assessed with experiments in both continuous and discontinuous regimes under close-to-real-life conditions. A pseudo-second order model yielded a better fit to the kinetic data. Application of the intraparticle diffusion model revealed two well-differentiated adsorption stages, in which the external material transfer is negligible and intraparticle diffusion is the controlling stage. The equilibrium study was better fitted to a Freundlich-type isotherm, predicting elevated maximum adsorption values (22.7 mg g−1) at a relatively low initial Cu (II) concentration (25 ppm), yielding a highly favorable chemisorption process (n >> 1). X-ray fluorescence study identified calcite (CaCO3) as the main component of marble waste sludges. According to X-ray diffraction analysis, Cu (II) ion adsorption occurred by intercalation of the metallic cation between CaCO3 layers and by the formation of surface complexes such as CaCO3 and Cu2(CO3)(OH)2. Cu (II) was more effectively removed at medium pH, lower temperature, and lower ionic strength of the aqueous medium. The salinity and dissolved organic matter in surface, ground-, and waste-waters negatively affected the Cu (II) removal process in both continuous and discontinuous regimes by competing for active adsorption sites. These findings demonstrate the applicability and effectiveness of marble-derived waste sludges as low-cost and readily available adsorbents for the treatment of waters polluted by Cu (II) under close-to-real-life conditions.

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Quality of life in HCV patients treated with OBV/PTV/r ± DSV ± RBV under real-life conditions – Data from the German observational study LIFE-C

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612887 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

P Buggisch ◽

R Link ◽

U Naumann ◽

G Teuber ◽

R Heyne ◽

...

Keyword(s):

Quality Of Life ◽

Observational Study ◽

Real Life ◽

Life Conditions

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Self-Recognizing π-π Stacking Interactions Designed for the Generation of Ultrastable Mesoporous Hydrogen-Bonded Organic Frameworks

10.26434/chemrxiv.9729494 ◽

2019 ◽

Author(s):

KAIKAI MA ◽

Peng Li ◽

John Xin ◽

Yongwei Chen ◽

Zhijie Chen ◽

...

Keyword(s):

Pore Size ◽

Fiber Composite ◽

Aqueous Media ◽

Stacking Interactions ◽

Mustard Gas ◽

X Ray Diffraction ◽

X Ray ◽

Expansion Strategy ◽

Π Stacking ◽

Hydrogen Bonded

Creating crystalline porous materials with large pores is typically challenging due to undesired interpen-etration, staggered stacking, or weakened framework stability. Here, we report a pore size expansion strategy by self-recognizing π-π stacking interactions in a series of two-dimensional (2D) hydrogen–bonded organic frameworks (HOFs), HOF-10x (x=0,1,2), self-assembled from pyrene-based tectons with systematic elongation of π-conjugated molecular arms. This strategy successfully avoids interpene-tration or staggered stacking and expands the pore size of HOF materials to access mesoporous HOF-102, which features a surface area of ~ 2,500 m2/g and the largest pore volume (1.3 cm3/g) to date among all reported HOFs. More importantly, HOF-102 shows significantly enhanced thermal and chemical stability as evidenced by powder x-ray diffraction and N2 isotherms after treatments in chal-lenging conditions. Such stability enables the adsorption of dyes and cytochrome c from aqueous media by HOF-102 and affords a processible HOF-102/fiber composite for the efficient photochemical detox-ification of a mustard gas simulant.

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Change in Patient-Reported Outcomes in Severe Eosinophilic Asthma Patients Treated With Benralizumab Under Real-life Conditions

Case Medical Research ◽

10.31525/ct1-nct04184284 ◽

2019 ◽

Author(s):

Keyword(s):

Patient Reported Outcomes ◽

Real Life ◽

Eosinophilic Asthma ◽

Severe Eosinophilic Asthma ◽

Life Conditions ◽

Patient Reported ◽

Asthma Patients

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Faculty Opinions recommendation of Screening for latent tuberculosis infection: performance of tuberculin skin test and interferon-γ release assays under real-life conditions.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717961853.793464482 ◽

2012 ◽

Author(s):

David Scott ◽

Nicola Gullick

Keyword(s):

Tuberculin Skin Test ◽

Skin Test ◽

Latent Tuberculosis Infection ◽

Real Life ◽

Latent Tuberculosis ◽

Interferon Γ ◽

Tuberculosis Infection ◽

Life Conditions

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Surface and interface analysis of iron sulfides in aqueous media using X-ray photoelectron spectroscopy of fast-frozen dispersions

Applied Surface Science ◽

10.1016/j.apsusc.2021.149261 ◽

2021 ◽

Vol 549 ◽

pp. 149261

Author(s):

Yuri Mikhlin ◽

Alexander Romanchenko ◽

Yevgeny Tomashevich

Keyword(s):

Photoelectron Spectroscopy ◽

Aqueous Media ◽

Iron Sulfides ◽

X Ray ◽

Interface Analysis ◽

Surface And Interface

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Nitration of Jharia basin coals, India: a study of structural modifications by XRD and FTIR techniques

International Journal of Coal Science & Technology ◽

10.1007/s40789-021-00422-8 ◽

2021 ◽

Author(s):

Prabal Boral ◽

Atul K. Varma ◽

Sudip Maity

Keyword(s):

Acetic Acid ◽

Nitric Acid ◽

Linear Relationship ◽

Glacial Acetic Acid ◽

Vitrinite Reflectance ◽

Aqueous Media ◽

Interlayer Spacing ◽

Acetic Acid Medium ◽

X Ray ◽

The Media

AbstractFour coal samples from Jharia basin, India are treated with nitric acid in glacial acetic acid and aqueous media to find out the chemical, petrographic and spatial structure of the organic mass by X-ray diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR) techniques. X-ray parameters of coal like interlayer spacing (d002), crystallite size (Lc), aroamticity (fa), average number of aromatic layers (Nc), and coal rank (I26/I20) have been determined using profile-fitting software. Considerable variation is observed in treated coals in comparison to the demineralized coals. The d002 values of treated coals have increased in both the media showing increase in disordering of organic moieties. A linear relationship has been observed between d002 values with the volatile matter of the coals. Similarly, the d002 values show linear relationship with Cdmf contents for demineralized as well as for the treated coals in both the media. The Lc and Nc values have decreased in treated coals corresponding to demineralized coals. The present study shows that nitration in both the media is capable of removing the aliphatic side chains from the coals and aromaticity (fa) increases with increase in rank and shows a linear relationship with the vitrinite reflectance. The corresponding I26/I20 values are least for treated coals in glacial acetic acid medium followed by raw and then to treated coals in aqueous medium. FTIR studies show that coal arenes of the raw coals are converted into nitro-arenes in structurally modified coals (SMCs) in both the media, the corresponding bands at 1550–1490 and 1355–1315 cm−1 respectively. FTIR study confirms that nitration is the predominant phenomenon, though, oxidation and nitration phenomena takes place simultaneously during treatment with nitric acid to form SMCs. In comparison to raw coals, the SMCs show higher aromaticity and may be easily converted to coal derived products like activated carbon and specialty carbon materials.

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A Sustainable Biomineralization Approach for the Synthesis of Highly Fluorescent Ultra-Small Pt Nanoclusters

Biosensors ◽

10.3390/bios9040128 ◽

2019 ◽

Vol 9 (4) ◽

pp. 128 ◽

Cited By ~ 4

Author(s):

Rajkamal Balu ◽

Robert Knott ◽

Christopher M. Elvin ◽

Anita J. Hill ◽

Namita R. Choudhury ◽

...

Keyword(s):

Quantum Yield ◽

Photoelectron Spectroscopy ◽

Photophysical Properties ◽

Conformational Dynamics ◽

Aqueous Media ◽

Intrinsically Disordered Protein ◽

X Ray ◽

Pt Nanoclusters ◽

Intrinsically Disordered ◽

Green Fluorescent

Herein we report the first example of a facile biomineralization process to produce ultra-small-sized highly fluorescent aqueous dispersions of platinum noble metal quantum clusters (Pt-NMQCs) using a multi-stimulus responsive, biomimetic intrinsically disordered protein (IDP), Rec1-resilin. We demonstrate that Rec1-resilin acts concurrently as the host, reducing agent, and stabilizer of the blue-green fluorescent Pt-NMQCs once they are being formed. The photophysical properties, quantum yield, and fluorescence lifetime measurements of the synthesized Pt-NMQCs were examined using UV-Vis and fluorescence spectroscopy. The oxidation state of the Pt-NMQCs was quantitatively analyzed using X-ray photoelectron spectroscopy. Both a small angle X-ray scattering technique and a modeling approach have been attempted to present a detailed understanding of the structure and conformational dynamics of Rec1-resilin as an IDP during the formation of the Pt-NMQCs. It has been demonstrated that the green fluorescent Pt-NMQCs exhibit a high quantum yield of ~7.0% and a lifetime of ~9.5 ns in aqueous media. The change in photoluminescence properties due to the inter-dot interactions between proximal dots and aggregation of the Pt-NMQCs by evaporation was also measured spectroscopically and discussed.

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An expandable approach for design and personalization of digital, just-in-time adaptive interventions

Journal of the American Medical Informatics Association ◽

10.1093/jamia/ocy160 ◽

2018 ◽

Vol 26 (3) ◽

pp. 198-210 ◽

Cited By ~ 3

Author(s):

Suat Gonul ◽

Tuncay Namli ◽

Sasja Huisman ◽

Gokce Banu Laleci Erturkmen ◽

Ismail Hakki Toroslu ◽

...

Keyword(s):

Real Life ◽

Personal Data ◽

Just In Time ◽

Intervention Design ◽

Intervention Delivery ◽

Life Conditions ◽

Triggering Conditions ◽

Delivery Strategies ◽

Design Mechanism ◽

Personalized Intervention

AbstractObjectiveWe aim to deliver a framework with 2 main objectives: 1) facilitating the design of theory-driven, adaptive, digital interventions addressing chronic illnesses or health problems and 2) producing personalized intervention delivery strategies to support self-management by optimizing various intervention components tailored to people’s individual needs, momentary contexts, and psychosocial variables.Materials and MethodsWe propose a template-based digital intervention design mechanism enabling the configuration of evidence-based, just-in-time, adaptive intervention components. The design mechanism incorporates a rule definition language enabling experts to specify triggering conditions for interventions based on momentary and historical contextual/personal data. The framework continuously monitors and processes personal data space and evaluates intervention-triggering conditions. We benefit from reinforcement learning methods to develop personalized intervention delivery strategies with respect to timing, frequency, and type (content) of interventions. To validate the personalization algorithm, we lay out a simulation testbed with 2 personas, differing in their various simulated real-life conditions.ResultsWe evaluate the design mechanism by presenting example intervention definitions based on behavior change taxonomies and clinical guidelines. Furthermore, we provide intervention definitions for a real-world care program targeting diabetes patients. Finally, we validate the personalized delivery mechanism through a set of hypotheses, asserting certain ways of adaptation in the delivery strategy, according to the differences in simulation related to personal preferences, traits, and lifestyle patterns.ConclusionWhile the design mechanism is sufficiently expandable to meet the theoretical and clinical intervention design requirements, the personalization algorithm is capable of adapting intervention delivery strategies for simulated real-life conditions.

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Acemetacin cocrystals and salts: structure solution from powder X-ray data and form selection of the piperazine salt

IUCrJ ◽

10.1107/s2052252514004229 ◽

2014 ◽

Vol 1 (2) ◽

pp. 136-150 ◽

Cited By ~ 37

Author(s):

Palash Sanphui ◽

Geetha Bolla ◽

Ashwini Nangia ◽

Vladimir Chernyshev

Keyword(s):

Hydrogen Bonds ◽

Dissolution Rate ◽

Aqueous Medium ◽

Acid Amide ◽

Three Dimensional ◽

X Ray Diffraction ◽

Reference Drug ◽

X Ray ◽

Time Period ◽

Solid Form

Acemetacin (ACM) is a non-steroidal anti-inflammatory drug (NSAID), which causes reduced gastric damage compared with indomethacin. However, acemetacin has a tendency to form a less soluble hydrate in the aqueous medium. We noted difficulties in the preparation of cocrystals and salts of acemetacin by mechanochemical methods, because this drug tends to form a hydrate during any kind of solution-based processing. With the objective to discover a solid form of acemetacin that is stable in the aqueous medium, binary adducts were prepared by the melt method to avoid hydration. The coformers/salt formers reported are pyridine carboxamides [nicotinamide (NAM), isonicotinamide (INA), and picolinamide (PAM)], caprolactam (CPR),p-aminobenzoic acid (PABA), and piperazine (PPZ). The structures of an ACM–INA cocrystal and a binary adduct ACM–PABA were solved using single-crystal X-ray diffraction. Other ACM cocrystals, ACM–PAM and ACM–CPR, and the piperazine salt ACM–PPZ were solved from high-resolution powder X-ray diffraction data. The ACM–INA cocrystal is sustained by the acid...pyridine heterosynthon and N—H...O catemer hydrogen bonds involving the amide group. The acid...amide heterosynthon is present in the ACM–PAM cocrystal, while ACM–CPR contains carboxamide dimers of caprolactam along with acid–carbonyl (ACM) hydrogen bonds. The cocrystals ACM–INA, ACM–PAM and ACM–CPR are three-dimensional isostructural. The carboxyl...carboxyl synthon in ACM–PABA posed difficulty in assigning the position of the H atom, which may indicate proton disorder. In terms of stability, the salts were found to be relatively stable in pH 7 buffer medium over 24 h, but the cocrystals dissociated to give ACM hydrate during the same time period. The ACM–PPZ salt and ACM–nicotinamide cocrystal dissolve five times faster than the stable hydrate form, whereas the ACM–PABA adduct has 2.5 times faster dissolution rate. The pharmaceutically acceptable piperazine salt of acemetacin exhibits superior stability, faster dissolution rate and is able to overcome the hydration tendency of the reference drug.

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