scholarly journals Aggregation-Induced Emission of Tetraphenylethene-Conjugated Phenanthrene Derivatives and Their Bio-Imaging Applications

Nanomaterials ◽  
2018 ◽  
Vol 8 (9) ◽  
pp. 728 ◽  
Author(s):  
Duy Khuong Mai ◽  
Joomin Lee ◽  
Ilgi Min ◽  
Temmy Vales ◽  
Kyong-Hoon Choi ◽  
...  

In this study, a series of rationally designed emissive phenanthrene derivatives were synthesized and their aggregation-induced emission (AIE) properties in tetrahydrofuran (THF)/water mixtures were investigated. Two tetraphenylethene (TPE) segments were conjugated to both ends of the phenanthrene core at the para-positions and meta-positions, resulting in pTPEP and mTPEP derivatives, respectively. While the TPE-conjugated phenanthrene derivatives did not show any emission when dissolved in pure THF, they showed strong sky-blue emissions in water-THF mixtures, which is attributed to the restriction of intramolecular motions of TPE segments by aggregation. Furthermore, silica nanoparticles loaded with these AIE-active compounds were prepared and proved to be promising intracellular imaging agents.

RSC Advances ◽  
2015 ◽  
Vol 5 (1) ◽  
pp. 20-26 ◽  
Author(s):  
Hao Cheng ◽  
Chuanxi Wang ◽  
Zhenzhu Xu ◽  
Huihui Lin ◽  
Chi Zhang

Folic acid-conjugated nanocomposites with NIR fluorescence, water-solubility, and low toxicity are prepared and used as target-imaging agents for cancer cells.


2021 ◽  
Author(s):  
Sathya Ramalingam ◽  
Kalarical Janardhanan Sreeram ◽  
Raghava Rao Jonnalagadda

Silica nanoparticles has attracted a huge bio audience as a biosafe material for targeted delivery applications due to its ease of functionalisation, less toxicity, and bio-compatibility. However, poor knowledge of...


2015 ◽  
Vol 3 (45) ◽  
pp. 8775-8781 ◽  
Author(s):  
Yi-Feng Wang ◽  
Jing Che ◽  
Yong-Chao Zheng ◽  
Yuan-Yuan Zhao ◽  
Fei Chen ◽  
...  

Rigid structures provided by silica matrix restrict the intramolecular rotations of AIE molecules, and fluorescence of CWQ-11@SiO2 nanoparticles maintains excellent pH-, viscosity- and photo-stability, especially stable in simulated gastric fluid.


2018 ◽  
Vol 6 (19) ◽  
pp. 3078-3084 ◽  
Author(s):  
Kerem Bray ◽  
Leonard Cheung ◽  
Khondker Rufaka Hossain ◽  
Igor Aharonovich ◽  
Stella M. Valenzuela ◽  
...  

We report on the first demonstration of FNDs containing either silicon or nitrogen vacancy color centers for multi-color bio-imaging.


2020 ◽  
Author(s):  
Yujie Tu ◽  
Zheng Zhao ◽  
Jacky W Y Lam ◽  
Ben Zhong Tang

Restriction of intramolecular motion (RIM) is the widely-accpeted mechanism of aggregation-induced emission (AIE). In this concise and comprehensive perspective, four mechanistic models related to different nonradiative pathways are summarized with examples to disclose the connotation of RIM, and meaningful mechanistic topics for future researches are advised.


2020 ◽  
Vol 8 (41) ◽  
pp. 14587-14594
Author(s):  
Saisai Yan ◽  
Zhinong Gao ◽  
Hongyan Yan ◽  
Fei Niu ◽  
Zhengqin Zhang

A highly efficient ALHS was constructed based on the non-covalent assembly of fluorescent MSNs and RB in an aqueous environment.


2019 ◽  
Vol 55 (90) ◽  
pp. 13530-13533 ◽  
Author(s):  
Xinfeng Tao ◽  
Hui Chen ◽  
Sylvain Trépout ◽  
Jiayu Cen ◽  
Jun Ling ◽  
...  

Fluorescent and biocompatible polymersomes based on the amphiphilic block copolypeptoid P(TPE-NAG)-b-PSar are promising for bio-imaging and drug delivery applications.


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