scholarly journals The Sex–Gender Effects in the Road to Tailored Botanicals

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1637 ◽  
Author(s):  
Campesi ◽  
Romani ◽  
Franconi

Phenols are a wide family of phytochemicals that are characterized by large chemical diversity and are considered to bioactive molecules of foods, beverages, and botanicals. Although they have a multitude of biological actions, their beneficial effects are rarely evidenced in clinical practice. This may occur due to the presence of numerous confounders, such as the modulation of phenol bioavailability, which can be regulated by microbiota, age, sex-gender. Sex-gender is an important determinant of health and well-being, and has an impact on environmental and occupational risks, access to health care, disease prevalence, and treatment outcomes. In addition, xenobiotic responses may be strongly influenced by sex-gender. This review describes how sex–gender differentially influences the activities of phenols also in some critical periods of women life such as pregnancy and lactation, considering also the sex of fetuses and infants. Thus, sex–gender is a variable that must be carefully considered and should be used to propose directions for future research on the road to tailored medicine and nutrition.

Author(s):  
Suzanne Roff-Wexler

Following a brief review of literature on big data as well as wisdom, this chapter provides a definition of data-based wisdom in the context of healthcare organizations and their visions. The author addresses barriers and ways to overcome barriers to data-based wisdom. Insights from interviews with leading healthcare professionals add practical meaning to the discussion. Finally, future research directions and questions are suggested, including the role of synchronicity and serendipity in data-based wisdom. In this chapter, developing data-based wisdom systems that flourish Wisdom, Virtue, Intellect, and Knowledge are encouraged.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Kaare B. Mikkelsen ◽  
Yousef R. Tabar ◽  
Simon L. Kappel ◽  
Christian B. Christensen ◽  
Hans O. Toft ◽  
...  

AbstractSleep is a key phenomenon to both understanding, diagnosing and treatment of many illnesses, as well as for studying health and well being in general. Today, the only widely accepted method for clinically monitoring sleep is the polysomnography (PSG), which is, however, both expensive to perform and influences the sleep. This has led to investigations into light weight electroencephalography (EEG) alternatives. However, there has been a substantial performance gap between proposed alternatives and PSG. Here we show results from an extensive study of 80 full night recordings of healthy participants wearing both PSG equipment and ear-EEG. We obtain automatic sleep scoring with an accuracy close to that achieved by manual scoring of scalp EEG (the current gold standard), using only ear-EEG as input, attaining an average Cohen’s kappa of 0.73. In addition, this high performance is present for all 20 subjects. Finally, 19/20 subjects found that the ear-EEG had little to no negative effect on their sleep, and subjects were generally able to apply the equipment without supervision. This finding marks a turning point on the road to clinical long term sleep monitoring: the question should no longer be whether ear-EEG could ever be used for clinical home sleep monitoring, but rather when it will be.


1992 ◽  
Vol 13 ◽  
pp. 3-25
Author(s):  
Robin A. Remington

This analysis focuses on the dilemmas facing policymakers attempting the transition from one-party hegemonic systems to multiparty democracies in post-communist Europe. It investigates the hypothesis that the political conditions for building democracy and the economic conditions required for establishing market economies in these societies are at cross purposes. The author examines the role of the international political economy in the process of democratization in terms of a framework of three primary variables: identity, legitimacy, and security. In applying these variables to post-communist East Central Europe, five significant arenas emerge in which political and economic imperatives come into conflict. The analysis concludes with policy implications for Western decision-makers whose own future security needs and economic well-being are tied to successful transition from communism to viable democracy in East Central Europe and the former Soviet Union.


Big Data ◽  
2016 ◽  
pp. 2275-2299
Author(s):  
Suzanne Roff-Wexler

Following a brief review of literature on big data as well as wisdom, this chapter provides a definition of data-based wisdom in the context of healthcare organizations and their visions. The author addresses barriers and ways to overcome barriers to data-based wisdom. Insights from interviews with leading healthcare professionals add practical meaning to the discussion. Finally, future research directions and questions are suggested, including the role of synchronicity and serendipity in data-based wisdom. In this chapter, developing data-based wisdom systems that flourish Wisdom, Virtue, Intellect, and Knowledge are encouraged.


2021 ◽  
pp. 026921632110425
Author(s):  
Helena Kukla ◽  
Angélique Herrler ◽  
Julia Strupp ◽  
Raymond Voltz

Background: Awareness of the impending end of one’s life can pose profound existential challenges, thereby impairing well-being. Confronting one’s own end of life may be an approach to meet the psychological needs and consequently enhance overall well-being. Different approaches of confrontation have been evaluated positively using measures of psychosocial comfort. To date, there exists no systematic overview on the different ways of confrontation (e.g. psychosocial or individual coping approaches). Aim: To synthesize the existing knowledge on the effects of different approaches of confronting one’s own end of life on older individuals and those with a life-threatening disease. Design: A systematic review of quantitative, qualitative, and mixed-methods full research reports was conducted. The retrieved studies were screened and appraised for methodological quality by two independent reviewers based on MMAT and CASP. The findings were synthesized narratively using the meta-summary technique by Sandelowski and Barroso. Data sources: Medline, PsycINFO, and Web of Science were searched from inception to 12/2020. Results: N = 49 studies reported on different approaches of confronting one’s own end of life, including psychosocial interventions, meaning-enhancing approaches, educational programs, and learning from lived experiences. The results suggest a clear trend toward beneficial effects on psychosocial comfort (e.g. anxiety, sense of meaning, well-being). Conclusion: Low-threshold opportunities of confrontation have the potential to improve well-being and should be emphasized in practical implementation. The results can serve as a comprehensive basis for future research aiming to investigate the determinants of psychosocial comfort for people nearing the end of life.


2016 ◽  
Vol 12 (3) ◽  
pp. 498-512 ◽  
Author(s):  
Rod Martin ◽  
Nicholas A. Kuiper

Since the start of the 21st century, the investigation of various psychological aspects of humor and laughter has become an increasingly prominent topic of research. This growth can be attributed, in no small part, to the pioneering and creative work on humor and laughter conducted by Professor Rod Martin. Dr. Martin’s research interests in humor and laughter began in the early 1980s and continued throughout his 32 year long career as a professor of clinical psychology at the University of Western Ontario. During this time, Dr. Martin published numerous scholarly articles, chapters, and books on psychological aspects of humor and laughter. Professor Martin has just retired in July 2016, and in the present interview he recounts a number of research highlights of his illustrious career. Dr. Martin’s earliest influential work, conducted while he was still in graduate school, stemmed from an individual difference perspective that focused on the beneficial effects of sense of humor on psychological well-being. This research focus remained evident in many of Professor Martin’s subsequent investigations, but became increasingly refined as he developed several measures of different components of sense of humor, including both adaptive and maladaptive humor styles. In this interview, Dr. Martin describes the conceptualization, development and use of the Humor Styles Questionnaire, along with suggestions for future research and development. In doing so, he also discusses the three main components of humor (i.e., cognitive, emotional and interpersonal), as well as the distinctions and similarities between humor and laughter. Further highlights of this interview include Professor Martin’s comments on such diverse issues as the genetic versus environmental loadings for sense of humor, the multifaceted nature of the construct of humor, and the possible limitations of teaching individuals to use humor in a beneficial manner to cope with stress and enhance their social and interpersonal relationships.


1977 ◽  
Vol 21 (6) ◽  
pp. 482-484
Author(s):  
Robert M. Nicholson ◽  
Michael F. Smith

Research programs involving high school driver education, motorcyclist safety education, problem driver retraining, elderly driver retraining, handicapped driver training, commercial vehicle driver training, and an energy efficient driver training program are summarized. Some of the pros and cons of driver education are presented and problems with establishing valid on-the-road driver performance tests are discussed.


2018 ◽  
Vol 7 (4.15) ◽  
pp. 230
Author(s):  
Masnida Hussin ◽  
Nor Hanis Mohd Fouzi

Road safety awareness is one of the many awareness programs that are often highlighted and discussed around the world. The road accident statistics are increased due to the lack of exposure and awareness among communities about traffic environments and rules. Children are one of the most vulnerable populations involved in traffic accidents. The children are unable to familiarize themselves with the surroundings, especially when crossing the road. This research attempts to improve road-safety awareness among children by using computer games as a learning tool. Specifically, it determines the progress of knowledge on the road rules and conditions after the children using the tool. The computer online game is suitable methods to use for teaching them on road safety due to interactive application always intimate the children. Besides the survey questions that related to road traffic rules, we also measures the attitude towards road safety in the participant (i.e., children and adult). Descriptive analysis in frequency, mean, and percentage are used to describe the respondent’s information. Statistical Package for Social Science (SPSS) is used to analyze the findings. The overall findings show that all respondents have positive feedback on online games as a road safety tool. Interestingly, the significant output shows on the different knowledge about road safety when the children are analyzed for before and after they played the games. The future research is suggested to study the other group of participant as the respondent in this work is limited to the primary school children. It can be improved by involving the large sample size and wider location.                                                                                                                                           


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