scholarly journals Whey Protein Supplementation Compared to Collagen Increases Blood Nesfatin Concentrations and Decreases Android Fat in Overweight Women: A Randomized Double-Blind Study

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2051 ◽  
Author(s):  
Bruna M. Giglio ◽  
Raquel M. Schincaglia ◽  
Alexandre S. da Silva ◽  
Ieda C. S. Fazani ◽  
Paula A. Monteiro ◽  
...  

Protein supplements are usually used to control body weight, however, the impact of protein quality on body fat attenuation is unknown. We investigated the effects of isocaloric isoproteic supplementation of either whey protein (WG) or hydrolysed collagen supplementation (CG) on dietary intake, adiposity and biochemical markers in overweight women. Methods: In this randomized double-blind study, 37 women, [mean ± SE, age 40.6 ± 1.7 year; BMI (kg/m2) 30.9 ± 0.6], consumed sachets containing 40 g/day of concentrated whey protein (25 g total protein, 2.4 leucine, 1.0 valine, 1.5 isoleucine, n = 17) or 38 g/day of hydrolysed collagen (26 g total protein, 1.02 leucine, 0.91 valine, 0.53 isoleucine, n = 20) in the afternoon snack. The compliance was set at >70% of the total theoretical doses. The dietary intake was evaluated by a 6-day food record questionnaire. At the beginning and after eight weeks of follow-up, body composition was evaluated by using dual-energy X-ray absorptiometry and lipid profile, insulin resistance, C-reactive protein, adiponectin, leptin and nesfastin plasma concentrations were analyzed. Results: Supplements were isocaloric and isoproteic. There were no differences in caloric intake (p = 0.103), protein (p = 0.085), carbohydrate (p = 0.797) and lipids (p = 0.109) intakes. The branched chain amino acids (BCAA) (GC: 1.8 ± 0.1 g vs. WG: 5.5 ± 0.3 g, p < 0.001) and leucine intake (CG: 0.1 ± 0.1 g vs. WG: 2.6 ± 0.1 g, p < 0.001) were higher in WG compared to CG. BMI increased in the CG (0.2 ± 1.1 kg/m2, p = 0.044) but did not change in WG. WG decreased the android fat (−0.1 ± 0.3 kg, p = 0.031) and increased nesfatin concentrations (4.9 ± 3.2 ng/mL, p = 0.014) compared to CG. Conclusions: Whey protein supplementation in overweight women increased nesfatin concentrations and could promote increase of resting metabolic rate as part of body composition improvement programs compared to collagen supplementation for 8 weeks. Additionally, our findings suggest that collagen may not be an effective supplement for overweight women who are attempting to alter body composition.

2013 ◽  
Vol 7 (1) ◽  
pp. 13-19 ◽  
Author(s):  
Myra K. Tara ◽  
Jean Soon Park ◽  
Bridget D. Mathison ◽  
Lindsey L. Kimble ◽  
Boon P. Chew

Purpose: The objective of this study was to assess the protective effects of whey and soy protein supplementation on inflammatory response, oxidative damage and body composition in active female endurance athletes. Methods: Healthy female endurance athletes (18-25 y; n = 18) running at least one hour per day, five days per week were randomly assigned to consume 40 g whey or soy protein daily, in a 6-wk double-blind study. Blood samples were obtained following completion of a one hour run at baseline and wk 6, and analyzed for inflammatory and oxidative biomarkers. DXA scans were completed to determine body composition. Results: Whey protein intervention decreased (P> 0.05) plasma TBARS concentrations, indicating suppressed lipid peroxidation. Supplementation with soy protein had no effect on markers of oxidative damage and inflammation, but decreased (P> 0.05) reduced glutathione indicating a reduction in antioxidant activity. Protein supplementation had no significant effect on body composition. Conclusions: Supplementation with whey protein decreased lipid peroxidation in in female endurance athletes suggesting a potential antioxidative action, while soy protein did not improve biomarkers of oxidative damage and inflammation.


Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1445
Author(s):  
Iselin Vildmyren ◽  
Alfred Halstensen ◽  
Adrian McCann ◽  
Øivind Midttun ◽  
Per Magne Ueland ◽  
...  

Large quantities of protein-rich cod residuals, which are currently discarded, could be utilized for human consumption. Although fish fillet intake is related to beneficial health effects, little is known about the potential health effects of consuming cod residual protein powder. Fifty lean adults were randomized to consume capsules with 8.1 g/day of cod residual protein (Cod-RP) or placebo capsules (Control group) for eight weeks, in this randomized, double-blind study. The intervention was completed by 40 participants. Fasting glucose and insulin concentrations were unaffected by Cod-RP supplementation, whereas plasma concentrations of α-hydroxybutyrate, β-hydroxybutyrate and acetoacetate all were decreased compared with the Control group. Trimethylamine N-oxide concentration in plasma and urine were increased in the Cod-RP group compared with the Control group. To conclude, the reduction in these potential early markers of impaired glucose metabolism following Cod-RP supplementation may indicate beneficial glucoregulatory effects of cod residual proteins. Trimethylamine N-oxide appears to be an appropriate biomarker of cod residual protein intake in lean adults.


BioFactors ◽  
2016 ◽  
Vol 43 (1) ◽  
pp. 132-140 ◽  
Author(s):  
Katja Žmitek ◽  
Tina Pogačnik ◽  
Liljana Mervic ◽  
Janko Žmitek ◽  
Igor Pravst

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