scholarly journals Nutrient Extraction Lowers Postprandial Glucose Response of Fruit in Adults with Obesity as well as Healthy Weight Adults

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 766
Author(s):  
Rabab Alkutbe ◽  
Kathy Redfern ◽  
Michael Jarvis ◽  
Gail Rees
Keyword(s):  
Fruit Juice ◽  
Disease Risk ◽  
Risk Group ◽  
Postprandial Glucose ◽  
Glycemic Response ◽  
Healthy Weight ◽  
Glucose Response ◽  
Eating Fruit ◽  
Nutrient Extraction

Fruit consumption is recommended as part of a healthy diet. However, consumption of fruit in the form of juice is positively associated with type 2 diabetes risk, possibly due to resulting hyperglycemia. In a recent study, fruit juice prepared by nutrient extraction, a process that retains the fiber component, was shown to elicit a favorable glycemic index (GI), compared to eating the fruit whole, in healthy weight adults. The current study expanded on this to include individuals with obesity, and assessed whether the nutrient extraction of seeded fruits reduced GI in a higher disease risk group. Nutrient extraction was shown to significantly lower GI, compared to eating fruit whole, in subjects with obesity (raspberry/mango: 25.43 ± 18.20 vs. 44.85 ± 20.18, p = 0.034 and passion fruit/mango (26.30 ± 25.72 vs. 42.56 ± 20.64, p = 0.044). Similar results were found in those of a healthy weight. In summary, the current study indicates that the nutrient-extraction of raspberries and passionfruit mixed with mango lowers the GI, not only in healthy weight individuals, but also in those with obesity, and supports further investigation into the potential for nutrient extraction to enable increased fruit intake without causing a high glycemic response.

The clinical utility of the glycemic index and its application to mixed meals

1991 ◽  
Vol 69 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Clarie B. Hollenbeck ◽  
Ann M. Coulston
Keyword(s):  
Glycemic Index ◽  
Clinical Utility ◽  
Postprandial Glucose ◽  
Dependent Diabetes Mellitus ◽  
Glycemic Response ◽  
Glucose Response ◽  
Number Of Factors ◽  
Carbohydrate Intolerance ◽  
Low Glycemic Index

A classification of carbohydrate-containing foods based on their glycemic response to 50-g carbohydrate portions has recently been developed. The relative glycemic potency of many of these carbohydrate-containing foods have been compared, and these data have been published in the form of a glycemic index. It has been suggested that meals containing low glycemic index foods will result in a lower postprandial glucose response than meals with a higher glycemic index. However, whether or not these data will lead to a clinically useful reduction in postprandial hyperglycemia in individuals with carbohydrate intolerance remains controversial. In this review, we will try to delineate why we believe that the glycemic index, as currently developed, may be a specious issue. In addition, we will briefly discuss a number of factors that may explain the apparent discrepancy in viewpoints on this issue.Key words: glycemic index, noninsulin-dependent diabetes mellitus, glycemic response, dietary carbohydrate.

scholarly journals Twenty Minute Moderate-Intensity Post-Dinner Exercise Reduces the Postprandial Glucose Response in Chinese Patients with Type 2 Diabetes

2018 ◽  
Vol 24 ◽  
pp. 7170-7177 ◽  
Author(s):  
Zheng Li ◽  
Yun Hu ◽  
Rengna Yan ◽  
Huiqin Li ◽  
Danfeng Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Postprandial Glucose ◽  
Chinese Patients ◽  
Moderate Intensity ◽  
Glucose Response

Abstract P209: Effects of Blood Pressure Lowering on Vascular Outcomes in Different Cardiovascular Risk Groups Among Patients With Type 2 Diabetes: New Results From Advance

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Susan van Dieren ◽  
Andre Pascal Kengne ◽  
John Chalmers ◽  
Joline Beulens ◽  
Yvonne van der Schouw ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Risk ◽  
High Risk ◽  
Treatment Effects ◽  
Disease Risk ◽  
Risk Group ◽  
Absolute Risk ◽  
Risk Groups ◽  
High Risk Group

Background/Aim: Although patients with type 2 diabetes constitute a high risk group there is a gradation in cardiovascular risk which may lead to differences in outcomes and effects of treatment. The objective of this study was to assess for differences in treatment effects of the fixed combination of perindopril-indapamide across subgroups of cardiovascular risk. Methods: 11,140 patients with type 2 diabetes, participating in the ADVANCE trial, were randomized to perindopril-indapamide or matching placebo. The UKPDS risk engine was used to calculate baseline 5-year coronary heart disease risk and to stratify patients into three risk groups (0-10%; 10–15%; >15%). Endpoints were composites of major macrovascular and microvascular events. Homogeneity of treatment effects across risk subgroups were tested by adding interaction terms to the Cox models. Results: The median estimated 5-year coronary heart disease risk at baseline was 10% (IQR 7%−16%). 1000 macrovascular and 916 microvascular events were recorded during a median follow-up of 4.3 years. The relative treatment effects were similar across all risk groups for all endpoints, with no heterogeneity (all P -values for heterogeneity ≥ 0.38). The hazard ratios for combined macro- and microvascular events were 0.89 (95% confidence interval: 0.77–1.03) for the moderate-high risk group and 0.92 (0.81–1.03) for the very high risk group. The absolute risk reductions were greater in the highest risk groups, with numbers needed to treat ranging from 38 to 244. Conclusions: Reductions in relative risk achieved with the fixed combination of perindopril-indapamide among patients with type 2 diabetes were consistent across subgroups defined by baseline cardiovascular risk, but reductions in absolute risk were greatest in those with the highest initial risk. Acknowledgements: This research was supported by a program grant from the National Health and Medical Research Council of Australia, the Center for Translational Molecular Medicine (CTMM) and the Netherlands Heart Foundation, Dutch Diabetes Research Foundation and Dutch Kidney Foundation (PREDICCt).

Postprandial glucose response to Chinese foods in patients with type 2 diabetes

2004 ◽  
Vol 104 (12) ◽  
pp. 1854-1858 ◽  
Author(s):  
Eliza M.Y. Chan ◽  
Winnie M.W. Cheng ◽  
Sau-Cheung Tiu ◽  
Lily L.L. Wong
Keyword(s):  
Type 2 Diabetes ◽  
Postprandial Glucose ◽  
Glucose Response

scholarly journals Nutrient-extraction blender preparation reduces postprandial glucose responses from fruit juice consumption

2017 ◽  
Vol 7 (10) ◽  
pp. e288-e288 ◽  
Author(s):  
K M Redfern ◽  
◽  
V L Cammack ◽  
N Sweet ◽  
L A Preston ◽  
...  
Keyword(s):  
Fruit Juice ◽  
Postprandial Glucose ◽  
Nutrient Extraction

scholarly journals The Effect of Different Postprandial Exercise Types on Glucose Response to Breakfast in Individuals with Type 2 Diabetes

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1440
Author(s):  
Alessio Bellini ◽  
Andrea Nicolò ◽  
Rocco Bulzomì ◽  
Ilenia Bazzucchi ◽  
Massimo Sacchetti
Keyword(s):  
Type 2 Diabetes ◽  
Resistance Exercise ◽  
Aerobic Exercise ◽  
Repeated Measures ◽  
Area Under The Curve ◽  
Moderate Intensity ◽  
Glycemic Response ◽  
Experimental Conditions ◽  
Glucose Response

Postprandial exercise represents an important tool for improving the glycemic response to a meal. This study evaluates the effects of the combination and sequence of different exercise types on the postprandial glycemic response in patients with type 2 diabetes. In this repeated-measures crossover study, eight patients with type 2 diabetes performed five experimental conditions in a randomized order: (i) uninterrupted sitting (CON); (ii) 30 min of moderate intensity aerobic exercise (walking) (A); (iii) 30 min of combined aerobic and resistance exercise (AR); (iv) 30 min of combined resistance and aerobic exercise (RA); and (v) 15 min of resistance exercise (R). All the exercise sessions started 30 min after the beginning of a standardized breakfast. All the exercise conditions showed a significant attenuation of the post-meal glycemic excursion (P < 0.003) and the glucose incremental area under the curve at 0–120 min (P < 0.028) and 0–180 min (P < 0.048) compared with CON. A greater reduction in the glycemic peak was observed in A and AR compared to RA (P < 0.02). All the exercise types improved the post-meal glycemic response in patients with type 2 diabetes, with greater benefits when walking was performed alone or before resistance exercise.

scholarly journals Glycemic Index of (Zummita) A Commonly Barley Based Consumed Traditional Libyan Food

2015 ◽  
Vol 3 (6) ◽  
pp. 346
Author(s):  
Mohamed Ahmida ◽  
Akram Elshebli ◽  
Ahmed Elzigl ◽  
Elmutazbellah Siddek
Keyword(s):  
Blood Glucose ◽  
Glycemic Index ◽  
Traditional Food ◽  
Glycemic Response ◽  
Glucose Response ◽  
Barley Flour ◽  
Lack Of Information ◽  
Blood Glucose Concentrations ◽  
Prevention Of Diabetes

In Libya especially in Benghazi, Zummita is a traditional Libyan food consisting of 85% whole barley flour and is commonly consumed as a breakfast meal, and. Due to an increase in Type 2 diabetes and a lack of information on the effects of Zummita consumption on glycemic response, this study was performed to determine the glycemic index (GI) of Zummita. Fasted healthy subjects (6 males and 6 females) volunteered to consume either glucose or Zummita. The blood glucose concentrations were analyzed using capillary blood samples immediately before, 30, 60, 90 and 120 min after glucose or Zummita consumption. The GI value of Zummita was calculated by expressing the incremental area under the blood glucose response curve (IAUC) value for Zummita as a percentage of each subject’s average IAUC value for the glucose. The GI value of Zummita was found as 46.90 ± 7.56. This result indicates that Zummita should be classified as low GI food. More importantly, our result provides the GI value of a Libyan traditional food which was not determined previously. This valuable information will be significant for management and the prevention of diabetes mellitus in Libya and other countries having similar food tradition.

scholarly journals Resistant Starch Type 2 from Wheat Reduces Postprandial Glycemic Response with Concurrent Alterations in Gut Microbiota Composition

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 645
Author(s):  
Riley L. Hughes ◽  
William H. Horn ◽  
Peter Finnegan ◽  
John W. Newman ◽  
Maria L. Marco ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Resistant Starch ◽  
Postprandial Glucose ◽  
Glycemic Response ◽  
Microbial Composition ◽  
Double Blind ◽  
Important Indicator ◽  
Distal Intestine ◽  
Standard Breakfast

The majority of research on the physiological effects of dietary resistant starch type 2 (RS2) has focused on sources derived from high-amylose maize. In this study, we conduct a double-blind, randomized, placebo-controlled, crossover trial investigating the effects of RS2 from wheat on glycemic response, an important indicator of metabolic health, and the gut microbiota. Overall, consumption of RS2-enriched wheat rolls for one week resulted in reduced postprandial glucose and insulin responses relative to conventional wheat when participants were provided with a standard breakfast meal containing the respective treatment rolls (RS2-enriched or conventional wheat). This was accompanied by an increase in the proportions of bacterial taxa Ruminococcus and Gemmiger in the fecal contents, reflecting the composition in the distal intestine. Additionally, fasting breath hydrogen and methane were increased during RS2-enriched wheat consumption. However, although changes in fecal short-chain fatty acid (SCFA) concentrations were not significant between control and RS-enriched wheat roll consumption, butyrate and total SCFAs were positively correlated with relative abundance of Faecalibacterium, Ruminoccocus, Roseburia, and Barnesiellaceae. These effects show that RS2-enriched wheat consumption results in a reduction in postprandial glycemia, altered gut microbial composition, and increased fermentation activity relative to wild-type wheat.

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