scholarly journals Increased Omega-3 Fatty Acid Intake Is Inversely Associated with Subclinical Inflammation in Healthy Elderly Men, Based on the 2015–2018 Korean National Health and Nutrition Examination Survey

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 338
Author(s):  
Woojung Yang ◽  
Jong Hun Lee ◽  
Jae-woo Lee ◽  
Yonghwan Kim ◽  
Ye-Seul Kim ◽  
...  

(1) Background: Subclinical inflammation as a risk factor of cardiovascular diseases was clinically measured using C-reactive protein (CRP) level. (2) Methods: This study was cross-sectionally designed based the 2015–2018 Korean National Health and Nutrition Examination Survey (KNHANES). The ratio of daily omega-3 fatty acids to energy intake (ω3FA ratio) was classified into four quartile groups (Q1, <0.3%; Q2, 0.3%–<0.6%; Q3, 0.6%–<1.0%; and Q4, ≥1.0% in both sexes). Logistic regression analysis was conducted to investigate the association between the ω3FA ratio and subclinical inflammation defined as CRP levels ≥3 mg/dL. (3) Results: The ω3FA ratio in subjects without and with subclinical inflammation was 0.8% and 0.7% in men (p-value = 0.001), and 0.8% and 0.8% in women (p-value = 0.491), respectively. The prevalence of subclinical inflammation in males decreased with increasing quartile of ω3FA ratio (12.9%, 9.6%, 7.4%, and 7.7%, p-value = 0.033), while female prevalence was not significant among quartile groups. Compared to Q1, odds ratios (95% confidence intervals) for subclinical inflammation of Q2, Q3, and Q4 were 0.740 (0.465–1.177), 0.564 (0.341–0.930), and 0.549 (0.317–0.953) in males, and 1.066 (0.653–1.741), 1.105 (0.600–1.718), and 0.934 (0.556–1.571) in females after full adjustment. (4) Conclusion: The ω3FA ratio is associated with subclinical inflammation in men.

2020 ◽  
Vol 9 (12) ◽  
pp. 3856
Author(s):  
Woojung Yang ◽  
Jae-woo Lee ◽  
Yonghwan Kim ◽  
Jong Hun Lee ◽  
Hee-Taik Kang

(1) Background: Omega-3 fatty acids (ω3FAs) are known to improve protein anabolism, increase the sensitivity to anabolic stimuli, decrease lipogenesis, and stimulate lipid oxidation. We aim to investigate whether ω3FAs are associated with the prevalence of sarcopenic obesity (SO). (2) Methods: Data were obtained from the 2014–2018 Korean National Health and Nutrition Examination Survey. The ratio of daily ω3FA intake to energy intake (ω3FA ratio) was categorized into four quartile groups. (3) Results: The prevalence of SO from Q1 to Q4 was 8.9%, 11.3%, 11.0%, and 9.8% respectively, in men and 17.4%, 14.0%, 13.9%, and 10.1% respectively, in women. The ω3FA ratio in individuals with and without SO were 1.0% and 0.9% in men (p-value = 0.271) respectively, and 0.8% and 1.0% in women (p-value = 0.017), respectively. Compared with Q1, odds ratios (95% confidence intervals) of Q2, Q3, and Q4 of ω3FA ratios were 1.563 (0.802–3.047), 1.246 (0.611–2.542), and 0.924 (0.458–1.864) respectively, in men and 0.663 (0.379–1.160), 0.640 (0.372–1.102), and 0.246 (0.113–0.534) respectively, in women, after fully adjusting for confounding factors. (4) Conclusions: The ω3FA ratio was significantly higher in older females without SO than in older females with SO. The ω3FA ratio was associated with the prevalence of SO in elderly females.


2003 ◽  
Vol 49 (8) ◽  
pp. 1353-1357 ◽  
Author(s):  
Earl S Ford ◽  
Wayne H Giles ◽  
Gary L Myers ◽  
Nader Rifai ◽  
Paul M Ridker ◽  
...  

Abstract Background: The distribution of C-reactive protein (CRP) concentrations among children and young adults in the US is not known at present. Methods: We used data from 3348 US children and young adults 3–19 years of age who participated in the National Health and Nutrition Examination Survey, 1999–2000, to describe the distribution of CRP concentrations, based on results obtained with a high-sensitivity latex-enhanced turbidimetric assay. Results: The range of CRP concentrations was 0.1–90.8 mg/L (mean, 1.6 mg/L; geometric mean, 0.5 mg/L; median, 0.4 mg/L). CRP concentrations increased with age. Females 16–19 years of age had higher concentrations than males in this age range (P = 0.003). Mexican Americans had the highest CRP concentrations among the three major race or ethnic groups (P &lt;0.001). Conclusions: For the first time, these data describe the CRP concentration distribution among US children and young adults, based on results obtained with a high-sensitivity assay.


2020 ◽  
Author(s):  
Se-Won Park ◽  
Seong-Sik Park ◽  
Eun-Jung Kim ◽  
Won-Suk Sung ◽  
In-Hyuk Ha ◽  
...  

Abstract Background No studies have investigated the association between self-rated health (SRH) and high-sensitivity C-reactive protein (hs-CRP) in South Koreans. This study explored the association and analyzed any sex differences.Method Using data from the 2015-2017 Korea National Health and Nutrition Examination Survey, we analyzed the association between SRH and high group (>1.0 mg/L) in 14,544 Koreans aged ≥19 years who responded to the SRH survey and who had hs-CRP test results. Results The percentage of having a very poor to poor SRH was higher in the high hs-CRP level group (22.4%) than in the low level group (17.66%). Among males, the risk of a high hs-CRP level increased with worse SRH (adjusted for confounders; P for trend <0.001). After adjusting for all confounders, including chronic diseases, males with a very poor SRH showed higher odds ratio (OR) for high group than those with a very good SRH (fully adjusted OR, 1.74; 95% confidence interval, 1.04-2.90). Significant correlations were absent among females. Conclusions A poor SRH was correlated with low-grade inflammation (high hs-CRP level) among male Korean adults. The findings could be useful for developing health improvement programs and in goal setting at a national scale.


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