scholarly journals Cholesterol and Egg Intakes with Cardiometabolic and All-Cause Mortality among Chinese and Low-Income Black and White Americans

Nutrients ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 2094
Author(s):  
Xiong-Fei Pan ◽  
Jae-Jeong Yang ◽  
Loren P. Lipworth ◽  
Xiao-Ou Shu ◽  
Hui Cai ◽  
...  
Keyword(s):  
Low Income ◽  
Dietary Cholesterol ◽  
Black Americans ◽  
Positive Association ◽  
Inverse Association ◽  
White Americans ◽  
Cox Models ◽  
Black And White ◽  
All Cause Mortality ◽  
Cholesterol Intake

We examined the associations of dietary cholesterol and egg intakes with cardiometabolic and all-cause mortality among Chinese and low-income Black and White Americans. Included were 47,789 Blacks, 20,360 Whites, and 134,280 Chinese aged 40–79 years at enrollment. Multivariable Cox models with restricted cubic splines were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for mortality outcomes using intakes of 150 mg cholesterol/day and 1 egg/week as the references. Cholesterol intake showed a nonlinear association with increased all-cause mortality and a linear association with increased cardiometabolic mortality among Black Americans: HRs (95% CIs) associated with 300 and 600 mg/day vs. 150 mg/day were 1.07 (1.03–1.11) and 1.13 (1.05–1.21) for all-cause mortality (P-linearity = 0.04, P-nonlinearity = 0.002, and P-overall < 0.001) and 1.10 (1.03–1.16) and 1.21 (1.08–1.36) for cardiometabolic mortality (P-linearity = 0.007, P-nonlinearity = 0.07, and P-overall = 0.005). Null associations with all-cause or cardiometabolic mortality were noted for White Americans (P-linearity ≥ 0.13, P-nonlinearity ≥ 0.06, and P-overall ≥ 0.05 for both). Nonlinear inverse associations were observed among Chinese: HR (95% CI) for 300 vs. 150 mg/day was 0.94 (0.92–0.97) for all-cause mortality and 0.91 (0.87–0.95) for cardiometabolic mortality, but the inverse associations disappeared with cholesterol intake > 500 mg/day (P-linearity ≥ 0.12; P-nonlinearity ≤ 0.001; P-overall < 0.001 for both). Similarly, we observed a positive association of egg intake with all-cause mortality in Black Americans, but a null association in White Americans and a nonlinear inverse association in Chinese. In conclusion, the associations of cholesterol and egg intakes with cardiometabolic and all-cause mortality may differ across ethnicities who have different dietary patterns and cardiometabolic risk profiles. However, residual confounding remains possible.

scholarly journals Dietary cholesterol and egg intake in relation to incident cardiovascular disease and all-cause and cause-specific mortality in postmenopausal women

2020 ◽  
Author(s):  
Guo-Chong Chen ◽  
Li-Hua Chen ◽  
Yasmin Mossavar-Rahmani ◽  
Victor Kamensky ◽  
Aladdin H Shadyab ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Postmenopausal Women ◽  
Dietary Cholesterol ◽  
Saturated Fat ◽  
Inverse Association ◽  
Egg Consumption ◽  
All Cause Mortality ◽  
Specific Mortality ◽  
Cholesterol Intake ◽  
Incident Cardiovascular Disease

ABSTRACT Background The potential cardiovascular impact of dietary cholesterol intake has been actively debated for decades. Objectives We aimed to evaluate associations of dietary cholesterol and egg intakes with incident cardiovascular disease (CVD) and all-cause and cause-specific mortality. Methods We included 96,831 US postmenopausal women aged 50–79 y without known CVD or cancer during baseline enrollment (1993–1998) of the Women's Health Initiative. Dietary information was collected using a validated FFQ. Incident CVD [i.e., ischemic heart disease (IHD) and stroke] and all-cause and cause-specific mortality were ascertained and adjudicated through February 2018. Results A total of 9808 incident CVD cases and 19,508 all-cause deaths occurred during a median follow-up of 17.8 y and 18.9 y, respectively. After multivariable adjustment for traditional risk factors and key dietary nutrients including dietary saturated fat, there were modest associations of dietary cholesterol intake with incident CVD (HRQ5versusQ1: 1.12; 95% CI: 1.03, 1.21; P-trend &lt; 0.001) and all-cause mortality (HRQ5versusQ1: 1.09; 95% CI: 1.02, 1.15; P-trend &lt; 0.001). Significant positive associations were also observed between dietary cholesterol and incident IHD (P-trend = 0.007), incident ischemic stroke (P-trend = 0.002), and CVD mortality (P-trend = 0.002), whereas there was an inverse association for incident hemorrhagic stroke (P-trend = 0.037) and no association for mortality from cancer, Alzheimer disease/dementia, respiratory diseases, or other causes (P-trend &gt; 0.05). Higher egg consumption was also associated with modestly higher risk of incident CVD (P-trend = 0.004) and all-cause mortality (P-trend &lt; 0.001), with HRs of 1.14 (95% CI: 1.04, 1.25) and 1.14 (95% CI: 1.07, 1.22), respectively, when comparing ≥1 egg/d with &lt;1 egg/wk. Conclusions Both higher dietary cholesterol intake and higher egg consumption appeared to be associated with modestly elevated risk of incident CVD and all-cause mortality in US postmenopausal women.

scholarly journals Inequality in mortality between Black and White Americans by age, place, and cause and in comparison to Europe, 1990 to 2018

2021 ◽  
Vol 118 (40) ◽  
pp. e2104684118
Author(s):  
Hannes Schwandt ◽  
Janet Currie ◽  
Marlies Bär ◽  
James Banks ◽  
Paola Bertoli ◽  
...  
Keyword(s):  
Life Expectancy ◽  
Low Income ◽  
Black Americans ◽  
The United States ◽  
High Income ◽  
White Americans ◽  
Mortality Trends ◽  
American Life ◽  
White American ◽  
Black And White

Although there is a large gap between Black and White American life expectancies, the gap fell 48.9% between 1990 and 2018, mainly due to mortality declines among Black Americans. We examine age-specific mortality trends and racial gaps in life expectancy in high- and low-income US areas and with reference to six European countries. Inequalities in life expectancy are starker in the United States than in Europe. In 1990, White Americans and Europeans in high-income areas had similar overall life expectancy, while life expectancy for White Americans in low-income areas was lower. However, since then, even high-income White Americans have lost ground relative to Europeans. Meanwhile, the gap in life expectancy between Black Americans and Europeans decreased by 8.3%. Black American life expectancy increased more than White American life expectancy in all US areas, but improvements in lower-income areas had the greatest impact on the racial life expectancy gap. The causes that contributed the most to Black Americans’ mortality reductions included cancer, homicide, HIV, and causes originating in the fetal or infant period. Life expectancy for both Black and White Americans plateaued or slightly declined after 2012, but this stalling was most evident among Black Americans even prior to the COVID-19 pandemic. If improvements had continued at the 1990 to 2012 rate, the racial gap in life expectancy would have closed by 2036. European life expectancy also stalled after 2014. Still, the comparison with Europe suggests that mortality rates of both Black and White Americans could fall much further across all ages and in both high-income and low-income areas.

scholarly journals Christian America in Black and White: Racial Identity, Religious-National Group Boundaries, and Explanations for Racial Inequality

2018 ◽  
Vol 80 (3) ◽  
pp. 277-298 ◽  
Author(s):  
Samuel L Perry ◽  
Andrew L Whitehead
Keyword(s):  
Racial Inequality ◽  
White Supremacy ◽  
General Social Survey ◽  
Black Americans ◽  
White Americans ◽  
Racial Justice ◽  
Social Survey ◽  
Group Boundaries ◽  
Black And White ◽  
Group Identities

Abstract Recent research suggests that, for white Americans, conflating national and religious group identities is strongly associated with racism, xenophobia, and Islamophobia, prompting some to argue that claims about Christianity being central to American identity are essentially about reinforcing white supremacy. Prior work has not considered, however, whether such beliefs may influence the racial views of nonwhite Americans differently from white Americans. Drawing on a representative sample of black and white Americans from the 2014 General Social Survey, and focusing on explanations for racial inequality as the outcome, we show that, contrary to white Americans, black Americans who view being a Christian as essential to being an American are actually more likely to attribute black–white inequality to structural issues and less to blacks’ individual shortcomings. Our findings suggest that, for black Americans, connecting being American to being Christian does not necessarily bolster white supremacy, but may instead evoke and sustain ideals of racial justice.

scholarly journals Income and Marital Status Interact on Obesity Among Black and White Men

2019 ◽  
Vol 13 (1) ◽  
pp. 155798831982995 ◽  
Author(s):  
Caryn N. Bell ◽  
Roland J. Thorpe
Keyword(s):  
Marital Status ◽  
Black Men ◽  
Low Income ◽  
Positive Association ◽  
White Men ◽  
Poverty Line ◽  
High Income ◽  
Never Married ◽  
Black And White ◽  
Increased Risk

Racial disparities in obesity among men are accompanied by positive associations between income and obesity among Black men only. Race also moderates the positive association between marital status and obesity. This study sought to determine how race, income, and marital status interact on obesity among men. Using data from the 2007 to 2014 National Health and Nutrition Examination Survey, obesity was measured as body mass index ≥30 kg/m2 among 6,145 Black and White men. Income was measured by percentage of the federal poverty line and marital status was categorized as currently, formerly, or never married. Using logistic regression and interaction terms, the associations between income and obesity were assessed by race and marital status categories adjusted for covariates. Black compared to White (OR = 1.19, 95% CI [1.03, 1.38]), currently married compared to never married (OR = 1.45, 95% CI [1.24, 1.69]), and high-income men compared to low income men (OR = 1.26, 95% CI [1.06, 1.50]) had higher odds of obesity. A three-way interaction was significant and analyses identified that income was positively associated with obesity among currently married Black men and never married White men with the highest and lowest probabilities of obesity, respectively. High-income, currently married Black men had higher obesity rates and may be at increased risk for obesity-related morbidities.

TRENDS: Racial Resentment and Public Opinion across the Racial Divide

2019 ◽  
Vol 72 (4) ◽  
pp. 767-784 ◽  
Author(s):  
Cindy D. Kam ◽  
Camille D. Burge
Keyword(s):  
Public Opinion ◽  
Racial Inequality ◽  
Black Americans ◽  
White Americans ◽  
Black And White ◽  
Racial Resentment ◽  
Quantitative Examination ◽  
Racial Divide ◽  
Black Public Opinion

Research on racial resentment has been meticulously developed, tested, and analyzed with white Americans in mind—yet black Americans have also responded to this battery for the past three decades. To date, little to nothing is known about the implications of responses to the racial resentment battery among black Americans. A burgeoning literature on blacks’ intragroup attitudes suggests that over time, black Americans have increasingly attributed racial inequality to individual failings as opposed to structural forces. As such, unpacking blacks’ responses to the canonical racial resentment battery may provide further insight into the micro-foundations of black public opinion. Using survey data from 1986 to 2016, we engage in a systematic quantitative examination of the role of racial resentment in predicting black and white Americans’ opinions on racial policies, “race-coded” policies, and nonracialized policies. Along the way, we highlight the existence of wide heterogeneity among black respondents and call for further investigation that identifies similarities and differences in the foundations of white and black public opinion.

scholarly journals Plasma Selenium Biomarkers in Low Income Black and White Americans from the Southeastern United States

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e84972 ◽  
Author(s):  
Margaret K. Hargreaves ◽  
Jianguo Liu ◽  
Maciej S. Buchowski ◽  
Kushal A. Patel ◽  
Celia O. Larson ◽  
...  
Keyword(s):  
United States ◽  
Low Income ◽  
Southeastern United States ◽  
White Americans ◽  
Plasma Selenium ◽  
Black And White

scholarly journals Christian America in Black and White: Racial Identity, Religious-National Group Boundaries, and Explanations for Racial Inequality

2019 ◽  
Author(s):  
Samuel Perry ◽  
Andrew L Whitehead
Keyword(s):  
Racial Inequality ◽  
White Supremacy ◽  
General Social Survey ◽  
Black Americans ◽  
White Americans ◽  
Racial Justice ◽  
Social Survey ◽  
Group Boundaries ◽  
Black And White ◽  
Group Identities

Recent research suggests that, for white Americans, conflating national and religious group identities is strongly associated with racism, xenophobia, and Islamophobia, prompting some to argue that claims about Christianity being central to American identity are essentially about reinforcing white supremacy. Prior work has not considered, however, whether such beliefs may influence the racial views of nonwhite Americans differently from white Americans. Drawing on a representative sample of black and white Americans from the 2014 General Social Survey, and focusing on explanations for racial inequality as the outcome, we show that, contrary to white Americans, black Americans who view being a Christian as essential to being an American are actually more likely to attribute black–white inequality to structural issues and less to blacks’ individual shortcomings. Our findings suggest that, for black Americans, connecting being American to being Christian does not necessarily bolster white supremacy, but may instead evoke and sustain ideals of racial justice.

scholarly journals Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study

2020 ◽  
Author(s):  
Ulla T Schultheiss ◽  
Inga Steinbrenner ◽  
Matthias Nauck ◽  
Markus P Schneider ◽  
Fruzsina Kotsis ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Function ◽  
Thyroid Function ◽  
Positive Association ◽  
Inverse Association ◽  
All Cause Mortality ◽  
Disease Study ◽  
Reduced Kidney Function

Abstract Background Hypothyroidism and low free triiodothyronine (FT3) syndrome [low FT3 levels with normal thyroid-stimulating hormone (TSH)] have been associated with reduced kidney function cross-sectionally in chronic kidney disease (CKD) patients with severely reduced estimated glomerular filtration rate (eGFR) or end-stage kidney disease (ESKD). Results on the prospective effects of impaired thyroid function on renal events and mortality for patients with severely reduced eGFR or from population-based cohorts are conflicting. Here we evaluated the association between thyroid and kidney function with eGFR (cross-sectionally) as well as renal events and mortality (prospectively) in a large, prospective cohort of CKD patients with mild to moderately reduced kidney function. Methods Thyroid markers were measured among CKD patients from the German Chronic Kidney Disease study. Incident renal endpoints (combined ESKD, acute kidney injury and renal death) and all-cause mortality were abstracted from hospital records and death certificates. Time to first event analysis of complete data from baseline to the 4-year follow-up (median follow-up time 4.04 years) of 4600 patients was conducted. Multivariable linear regression and Cox proportional hazards models were fitted for single and combined continuous thyroid markers [TSH, free thyroxine (FT4), FT3] and thyroid status. Results Cross-sectionally, the presence of low-FT3 syndrome showed a significant inverse association with eGFR and continuous FT3 levels alone showed a significant positive association with eGFR; in combination with FT4 and TSH, FT3 levels also showed a positive association and FT4 levels showed a negative association with eGFR. Prospectively, higher FT4 and lower FT3 levels were significantly associated with a higher risk of all-cause mortality (Nevents = 297). Per picomole per litre higher FT3 levels the risk of reaching the composite renal endpoint was 0.73-fold lower (95% confidence interval 0.65–0.82; Nevents = 615). Compared with euthyroid patients, patients with low-FT3 syndrome had a 2.2-fold higher risk and patients with hypothyroidism had a 1.6-fold higher risk of experiencing the composite renal endpoint. Conclusions Patients with mild to moderate CKD suffering from thyroid function abnormalities are at an increased risk of adverse renal events and all-cause mortality over time.

scholarly journals Vitamin D Insufficiency and Hyperparathyroidism in a Low Income, Multiracial, Elderly Population1

2000 ◽  
Vol 85 (11) ◽  
pp. 4125-4130 ◽  
Author(s):  
Susan S. Harris ◽  
Elpidoforos Soteriades ◽  
Jo Anna Stina Coolidge ◽  
Sharmilla Mudgal ◽  
Bess Dawson-Hughes
Keyword(s):  
Vitamin D ◽  
Low Income ◽  
Positive Association ◽  
Vitamin D Insufficiency ◽  
Inverse Association ◽  
Hydroxyvitamin D ◽  
Vitamin D Intake ◽  
Northern Areas ◽  
25 Hydroxyvitamin D ◽  
Pth Level

This report examines the wintertime vitamin D and PTH status of 308 participants in the Boston Low Income Elderly Osteoporosis Study of noninstitutionalized low income elderly men and women (age, 64–100 yr) living in subsidized housing in Boston, MA. Twenty-one percent of the 136 black subjects and 11% of the 110 whites had very low plasma 25-hydroxyvitamin D (25OHD) concentrations (&lt;25 nmol/L), and 73% of the blacks and 35% of the whites had 25OHD concentrations less than 50 nmol/L. The mean 25OHD levels of the smaller Hispanic and Asian subsets were generally similar to those of the white subjects. In addition to race, significant predictors of 25OHD included vitamin D intake (positive association) and smoking (inverse association), but not sex or age. Low 25OHD concentrations were associated with increased PTH and reduced serum calcium. The PTH level in the black subjects was substantially higher than that in the white subjects, and this difference was only partially explained by the racial difference in 25OHD. Elderly individuals who live in northern areas, particularly African-Americans, should be strongly encouraged to increase their vitamin D intake, especially in winter.

scholarly journals Risk of endometrial cancer in relation to individual nutrients from diet and supplements

2011 ◽  
Vol 14 (11) ◽  
pp. 1948-1960 ◽  
Author(s):  
Rita K Biel ◽  
Ilona Csizmadi ◽  
Linda S Cook ◽  
Kerry S Courneya ◽  
Anthony M Magliocco ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Linear Trend ◽  
Dietary Cholesterol ◽  
Positive Association ◽  
Food Sources ◽  
Inverse Association ◽  
Nutrient Intakes ◽  
Adjusted Risk ◽  
Soluble Fibre ◽  
Increased Risk

AbstractObjectiveIntake of nutrients may influence the risk of endometrial cancer (EC). We aimed to estimate the association of intake of individual nutrients from food and from food plus supplements with EC occurrence.DesignA population-based case–control study conducted in Canada (2002–2006).SettingNutrient intakes from food and supplements were assessed using an FFQ. Logistic regression was used to estimate EC risk within quartile levels of nutrient intakes.SubjectsIncident EC cases (n 506) were identified from the Alberta Cancer Registry, and population controls were frequency- and age-matched to cases (n 981).ResultsThere existed little evidence of an association with EC for the majority of macronutrients and micronutrients examined. We observed a statistically significant increased risk associated with the highest, compared with the lowest, quartile of intake of dietary cholesterol (multivariable-adjusted OR = 1·51, 95 % CI 1·08, 2·11; P for trend = 0·02). Age-adjusted risk at the highest level of intake was significantly reduced for Ca from food sources (OR = 0·73, 95 % CI 0·54, 0·99) but was attenuated in the multivariable model (OR = 0·82, 95 % CI 0·59, 1·13). When intake from supplements was included in Ca intake, risk was significantly reduced by 28 % with higher Ca (multivariable-adjusted OR = 0·72, 95 % CI 0·51, 0·99, P for trend = 0·04). We also observed unexpected increased risks at limited levels of intakes of dietary soluble fibre, vitamin C, thiamin, vitamin B6 and lutein/zeaxanthin, with no evidence for linear trend.ConclusionsThe results of our study suggest a positive association between dietary cholesterol and EC risk and an inverse association with Ca intake from food sources and from food plus supplements.

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