scholarly journals Periconceptional Maternal Diet Characterized by High Glycemic Loading Is Associated with Offspring Behavior in NEST

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3180
Author(s):  
Candice L. Alick ◽  
Rachel L. Maguire ◽  
Susan K. Murphy ◽  
Bernard F. Fuemmeler ◽  
Cathrine Hoyo ◽  
...  

Maternal periconceptional diets have known associations with proper offspring neurodevelopment. Mechanisms for such associations include improper energy/nutrient balances between mother and fetus, as well as altered offspring epigenetics during development due to maternal nutrient and inflammatory status. Using a comprehensive food frequency questionnaire and assessing offspring temperament with the Infant-Toddler Social and Emotional Assessment (n = 325, mean age = 13.9 months), we sought to test whether a maternal periconceptional diet characterized by high glycemic loading (MGL) would affect offspring temperament using adjusted ordinal regression. After limiting false discovery to 10%, offspring born to mothers in tertile 3 of glycemic loading (referent = tertile 1) were more likely to be in the next tertile of anxiety [OR (95% CI) = 4.51 (1.88–11.07)] and inhibition-related behaviors [OR (95% CI) = 3.42 (1.49–7.96)]. Male offspring were more likely to exhibit impulsive [OR (95% CI) = 5.55 (1.76–18.33)], anxiety [OR (95% CI) = 4.41 (1.33–15.30)], sleep dysregulation [OR (95% CI) = 4.14 (1.34–13.16)], empathy [6.68 (1.95–24.40)], and maladaptive behaviors [OR (95% CI) = 9.86 (2.81–37.18)], while females were more likely to exhibit increased anxiety-related behaviors [OR (95% CI) = 15.02 (3.14–84.27)]. These associations persisted when concurrently modeled with the maternal–Mediterranean dietary pattern. In a subset (n = 142), we also found MGL associated with increased mean methylation of the imprint control region of SGCE/PEG10. In conclusion, these findings highlight the importance of maternal dietary patterns on offspring neurodevelopment, offering avenues for prevention options for mothers.

2018 ◽  
Vol 60 (2) ◽  
pp. 119-125
Author(s):  
Huda H. Alabbody ◽  
Ban S. Al- Nasiry ◽  
Khalida H. Kadhim

  Background: Breast cancer is the most common cancer among women and ranked number two afterlung cancer in the world. According to the World Health Organization, breast cancer accounts for22.9% among cancers in women in 2012.Objective: This study was designed to evaluate the dietary pattern particularly dairy productsconsumption and the role of lifestyle on women with breast cancer in Baghdad city and its suburbs.Subjects and Methods: The study was conducted on 100 women with breast cancer, as a case group,compared with a control group comprised of 100 healthy women. Demographic data were collectedfrom both groups. A food frequency questionnaire was used of 33 items of foods for reporting thedietary pattern and modes of life style of the participants. The statistical Chi-square test / SPSS V.22was used to analyze the data.Results: Our data show that 71% of the women in the two groups were found to be overweightwith body mass index (BMI 25-29.9). 90% of obese women represented in case group (BMI ≥30), while82% of normal weight women (BMI 18.5-24.9) were in control group. Approximately 61% of womenin both groups were in post-menopausal age. Intake of high fatty dairy products by the participantsshowed a statistically significant increase in breast cancer risk (OR=1.625, CIs 95%=0.686-3.847).Consumption of vegetables and fruits was significantly lower (P˂0.01) in case group than in the controlgroup. Furthermore, roughly 68% women in the case group used to smoke cigarettes. In addition, lackor decreased regular physical exercises (never with ≥1 practice per wk) was statistically significant(OR= 44. 809; CIs= 5.889 –340.963). Other parameters, including long period of breastfeeding, earlyage at first birth and consumption of white meat, beans and eggs were all reported to have significance.On the other hand, there was no correlation with the marital status, occupation, living area, class ofdairy products, and passive smoking.Conclusion: Unhealthy dietary habits especially high-fat dairy intake and wrong lifestyle may be riskfactors and predispose Iraqi women for breast cancer development. Therefore, eating healthy food andfollowing correct lifestyle are highly recommended as a suitable program for the prevention of breastcancer.


2020 ◽  
Vol 151 (S1) ◽  
pp. 37-44 ◽  
Author(s):  
Kit Ying Tsoi ◽  
Ruth S.M. Chan ◽  
Liz Sin Li ◽  
Fionnuala M. McAuliffe ◽  
Mark A. Hanson ◽  
...  

Nutrients ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 2183 ◽  
Author(s):  
Ewa Niedzwiedzka ◽  
Lidia Wadolowska ◽  
Joanna Kowalkowska

The aim of this study was to evaluate the test–retest reproducibility of a non-quantitative food frequency questionnaire (acronym: 62-item FFQ-6) and the possibility of identifying dietary patterns (DPs) in 13–21-year-old females. The study involved 97 females within three age groups: 13–15, 16–18, and 19–21 years, including 31, 38, and 28 subjects, respectively. The questionnaire was completed twice with a two-week interval (test and retest). For the total sample, using a principal component analysis (PCA), two similar PCA-driven DPs (DP1 and DP2) were identified separately from test data and retest data, considering two sets of input variables. 60-item-DP1 and 60-item-DP2 were identified after excluding two items—vegetables and fruits in general—due to including single items of various kinds of vegetables and fruits. After an aggregation of some items of the questionnaire, 25-item-DP1 and 25-item-DP2 were identified. The kappa statistic (test vs. retest) in the total sample averaged at 0.52 (0.32–0.72 for food items), while within age groups, it averaged at 0.41, 0.53, and 0.65, respectively. The percentage of subjects classified into the same food frequency category (test vs. retest) in the total sample averaged at 68% (51%–89% for food items), while within age groups, it averaged at 60%, 68%, and 77%, respectively. The Spearman correlations between dietary pattern scores (test vs. retest) in the total sample were: 0.84 (within age groups 0.83, 0.81, and 0.78, respectively) for 60-item-DP1, 0.68 (within age groups 0.24, 0.79, and 0.76, respectively) for 60-item-DP2, 0.76 (within age groups 0.56, 0.82, and 0.89, respectively) for 25-item-DP1, and 0.48 (within age groups 0.40, 0.57, and 0.53, respectively) for 25-item-DP2 (p < 0.05 for all). In conclusion, the test–retest reproducibility of the 62-item FFQ-6 was good or very good for most food items, with a tendency to be higher in older age groups of females under study. Due to the acceptable-to-good reproducibility of dietary pattern identification, the use of a 62-item FFQ-6 to describe the overall diet of young Polish females can be recommended.


2020 ◽  
pp. 135910532090988
Author(s):  
Maryam Lahouti ◽  
Roza Zavoshy ◽  
Mostafa Noroozi ◽  
Reza Rostami ◽  
Maryam Gholamalizadeh ◽  
...  

We aimed to investigate the association between dietary patterns and depressive symptoms among 217 Iranian women aged 20–45 years. In this study, dietary intake was assessed using a valid and reliable semi-quantitative food frequency questionnaire. A principal component analysis was applied to detect the major dietary patterns. The Beck Depression Inventory was used to assess the depressive symptoms. Two major dietary patterns were identified: the “semi-Mediterranean” dietary pattern and the “western” dietary pattern. Participants with the “western” dietary pattern had a higher rate of depressive symptoms ( p < 0.05). However, the “semi-Mediterranean” dietary pattern had no significant association with the depressive symptoms.


Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4334
Author(s):  
Sujin Song ◽  
Kyueun Lee ◽  
Soim Park ◽  
Nara Shin ◽  
Hyunju Kim ◽  
...  

The relationship between the various types of diets derived from plants and vulnerability of dyslipidemia has rarely been investigated, and limited data exist in Asians whose dietary pattern is fairly different from that of the Western population. We aim to analyze the relationship between three plant-based diet indices (PDI) and the risk of dyslipidemia. Participants included 173,209 Korean adults who were aged ≥40 years from the Korean Genome and Epidemiology Study_Health Examination (2004–2013). A food frequency questionnaire (FFQ) was used to assess dietary intake. Three PDI were quantified for the study: overall PDI, healthful PDI (hPDI), and unhealthful PDI (uPDI). Among the 147,945 included, 48,166 (32.6%) of participants had dyslipidemia. Great adherence to uPDI was related with 15% greater odds of having dyslipidemia (OR: 1.15; 95% CI: 1.11–1.20, p-trend < 0.0001). No significant association was observed between PDI, hPDI, and dyslipidemia. The association between uPDI and dyslipidemia was significantly stronger among participants aged ≥55 years when compared to participants aged <55 years (p-value for interaction = 0.001). The quality of plant foods is vital in preventing dyslipidemia among people consuming high plant-based food diets.


2018 ◽  
Vol 60 (2) ◽  
pp. 119-125
Author(s):  
Huda H. Alabbody ◽  
Ban S. Al- Nasiry ◽  
Khalida H. Kadhim

  Background: Breast cancer is the most common cancer among women and ranked number two afterlung cancer in the world. According to the World Health Organization, breast cancer accounts for22.9% among cancers in women in 2012.Objective: This study was designed to evaluate the dietary pattern particularly dairy productsconsumption and the role of lifestyle on women with breast cancer in Baghdad city and its suburbs.Subjects and Methods: The study was conducted on 100 women with breast cancer, as a case group,compared with a control group comprised of 100 healthy women. Demographic data were collectedfrom both groups. A food frequency questionnaire was used of 33 items of foods for reporting thedietary pattern and modes of life style of the participants. The statistical Chi-square test / SPSS V.22was used to analyze the data.Results: Our data show that 71% of the women in the two groups were found to be overweightwith body mass index (BMI 25-29.9). 90% of obese women represented in case group (BMI ≥30), while82% of normal weight women (BMI 18.5-24.9) were in control group. Approximately 61% of womenin both groups were in post-menopausal age. Intake of high fatty dairy products by the participantsshowed a statistically significant increase in breast cancer risk (OR=1.625, CIs 95%=0.686-3.847).Consumption of vegetables and fruits was significantly lower (P˂0.01) in case group than in the controlgroup. Furthermore, roughly 68% women in the case group used to smoke cigarettes. In addition, lackor decreased regular physical exercises (never with ≥1 practice per wk) was statistically significant(OR= 44. 809; CIs= 5.889 –340.963). Other parameters, including long period of breastfeeding, earlyage at first birth and consumption of white meat, beans and eggs were all reported to have significance.On the other hand, there was no correlation with the marital status, occupation, living area, class ofdairy products, and passive smoking.Conclusion: Unhealthy dietary habits especially high-fat dairy intake and wrong lifestyle may be riskfactors and predispose Iraqi women for breast cancer development. Therefore, eating healthy food andfollowing correct lifestyle are highly recommended as a suitable program for the prevention of breastcancer.


2012 ◽  
Vol 37 (03) ◽  
Author(s):  
N Steinemann ◽  
IU Leonhäuser ◽  
N Probst-Hensch ◽  
L Grize ◽  
C Brombach

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