scholarly journals Children with Intestinal Failure Maintain Their Renal Function on Long-Term Parenteral Nutrition

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3647
Author(s):  
Anat Guz Mark ◽  
Shelly Levi ◽  
Miriam Davidovits ◽  
Luba Marderfeld ◽  
Raanan Shamir
Keyword(s):  
Renal Function ◽  
Parenteral Nutrition ◽  
Intestinal Failure ◽  
Cross Sectional Study ◽  
Low Grade ◽  
Base Line ◽  
Cross Sectional ◽  
Abdominal Sonography ◽  
Renal Complications

Background: Long-term parenteral nutrition (PN) has been associated with renal complications, including hypercalciuria, nephrocalcinosis, proteinuria and reduced glomerular filtration rate (GFR). Pediatric data are scarce and mostly short-term. Our study aimed to evaluate renal complications in children with intestinal failure (IF) receiving long-term PN. Methods: A cross-sectional study was performed in a tertiary pediatric IF clinic of patients receiving home-PN treatment for more than 1 year. Data regarding medical background, anthropometrics, laboratory investigations and abdominal sonography were retrieved. Results: Complete data were available for 15 children (67% males), with a median age of 6 (range 1.5–15) years and a median (IQR) PN duration of 4 (1.5–6) years. Low-grade proteinuria was identified in 61% and microalbuminuria in 30% of the cohort. Hypercalciuria and hyperoxaluria were present in 50% and 46%, respectively. One patient had nephrocalcinosis. The estimated GFR was normal in all but one patient who had pre-existing kidney disease. Conclusions: Pediatric IF patients can present with preserved kidney function after years of PN treatment. Despite the high prevalence of hypercalciuria, nephrocalcinosis was not common. Base line and long-term monitoring of various aspects of renal function would be essential to characterize the effects of prolonged PN on kidney functions in pediatric patients.

scholarly journals Association between occupational or environmental noise exposure and renal function among middle-aged and older Korean adults: a cross-sectional study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
You Jin Kim ◽  
Won-Jun Choi ◽  
Seunghon Ham ◽  
Seong-Kyu Kang ◽  
Wanhyung Lee
Keyword(s):  
Renal Function ◽  
Auditory System ◽  
Noise Exposure ◽  
Exposure Period ◽  
Environmental Noise ◽  
Cross Sectional Study ◽  
Occupational Noise ◽  
Cross Sectional ◽  
Occupational Noise Exposure

AbstractExposure to occupational and environmental noise is closely linked to various auditory system diseases. Few studies have focused on the effect of noise exposure on the extra auditory system, especially the urinary system. We analyzed 17,154 participants aged 40–79 years from the Korea National Health and Nutrition Examination Survey between 2013 and 2018. A self-reported questionnaire was used to assess occupational or environmental noise exposure. Logistic regression was used to determine the differences in the prevalence of chronic kidney disease (CKD) based on noise exposure characteristics. For participants with noise exposure, linear regression was performed to determine relationship of the noise exposure period and estimated glomerular filtration rate (eGFR). In the noise exposure group, a higher CKD prevalence was associated with females who experienced long-term occupational noise (≥ 240 months) (adjusted OR 2.72, 95% CI 1.11–6.66). An increase of one month of occupational noise exposure was associated with a 0.0106 mL/min/1.73 m2 decrease in eGFR in females aged < 60 years. Overall, noise exposure may be a risk factor for reduced renal function, especially long-term occupational noise exposure. More precise studies should determine (1) the relationship between noise and renal function and (2) the underlying mechanisms.

scholarly journals Association Between Occupational or Environmental Noise Exposure and Renal Function Among Middle-aged and Older Korean Population: A Cross-sectional Study

2021 ◽  
Author(s):  
You Jin Kim ◽  
Won-Jun Choi ◽  
Seunghon Ham ◽  
Seong-Kyu Kang ◽  
Wanhyung Lee
Keyword(s):  
Renal Function ◽  
Auditory System ◽  
Noise Exposure ◽  
Exposure Period ◽  
Environmental Noise ◽  
Cross Sectional Study ◽  
Occupational Noise ◽  
Cross Sectional ◽  
Exposure Effect

Abstract Exposure to occupational and environmental noise is closely linked to various diseases of auditory system. Few studies have focused on noise exposure effect on extra auditory system especially, urinary system. This study analyzed 17,202 participants aged 40–79 years from the Korea National Health and Nutrition Examination Survey between 2013 and 2018. A self-reported questionnaire was used to assess occupational or environmental noise exposure. Logistic regression was used to determine the differences in chronic kidney disease (CKD) prevalence considering noise exposure characteristics. For participants with noise exposure, linear regression was performed to determine the noise exposure period and estimated glomerular filtration rate (eGFR). In the noise exposure group, a higher CKD prevalence was associated with females who experienced long-term occupational noise (≥ 240 months), compared with the other groups (Adjusted OR = 2.86, 95% CI: 1.18–6.94). An increase of one month of occupational noise exposure was associated with a 0.0096 mL/min/1.73 m2, 0.0080 mL/min/1.73 m2, and 0.0159 mL/min/1.73 m2 decrease of eGFR in total, in males, and in females, respectively. Our results suggest that noise exposure can be a risk factor for reduced renal function, especially long-term exposure to occupational noise. More precise studies are necessary to determine the relationship between noise and renal function and the underlying mechanisms.

Chronic dehydration may impair renal function in patients with chronic intestinal failure on long-term parenteral nutrition

2006 ◽  
Vol 25 (1) ◽  
pp. 75-81 ◽  
Author(s):  
M LAUVERJAT ◽  
A HADJAISSA ◽  
P VANHEMS ◽  
P BOULETREAU ◽  
D FOUQUE ◽  
...  
Keyword(s):  
Renal Function ◽  
Parenteral Nutrition ◽  
Intestinal Failure ◽  
Impair Renal Function

scholarly journals Survey-Based Analysis of Current Trends for Prescribing Gastrointestinal Protectants among Small-Animal General Practitioners in Portugal

2021 ◽  
Vol 8 (5) ◽  
pp. 70
Author(s):  
Rita Baptista ◽  
Ryane Englar ◽  
Berta São Braz ◽  
Rodolfo Oliveira Leal
Keyword(s):  
General Practitioners ◽  
Healthcare Providers ◽  
Small Animal ◽  
Cross Sectional Study ◽  
Online Forums ◽  
Educational Strategies ◽  
Cross Sectional ◽  
Current Trends ◽  
Therapeutic Value

In both human and veterinary healthcare, gastrointestinal protectants (GIPs) are considered a staple of clinical practice in that they are prescribed by general practitioners (GPs) and specialists alike. Concerning GIP use, overprescription of proton pump inhibitors (PPIs) has become a growing concern among human healthcare providers. This trend has also been documented within veterinary practice, prompting the American College of Veterinary Internal Medicine (ACVIM) to publish a consensus statement in 2018 concerning evidence-based indications for GIP use. This observational cross-sectional study evaluated self-reported prescribing protocols among Portuguese GPs to determine whether there is adherence to the consensus guidelines. Respondents were Portuguese GPs recruited by social media posts in veterinarian online forums. Data were collected from 124 respondents concerning their GIPs of choice and their rationales for prescribing them. Data were mined for prescription patterns and protocols. Among GIPs, PPIs were prescribed more often. Rationales for use included gastrointestinal ulceration and erosion (GUE), prophylactic management of nonerosive gastritis, pancreatitis, reflux esophagitis, and steroid-induced ulceration. Once-daily administration of PPIs was the most frequent dosing regime among respondents. Ninety-six percent of PPI prescribers advocated that the drug be administered either shortly before or at mealtime. Forty-nine percent of respondents supported long-term use of PPIs. Fifty-nine percent of respondents acknowledged discontinuing PPIs abruptly. This study supports that Portuguese GPs commonly prescribe GIPs in accordance with ACVIM recommendations to medically manage GUE. However, misuse of GIPs does occur, and they have been prescribed where their therapeutic value is debatable. Educational strategies should target GPs in an effort to reduce GIP misuse.

scholarly journals A Cross-Sectional Study on the Impacts of Perceived Job Value, Job Maintenance, and Social Support on Burnout among Long-Term Care Staff in Hawaii

2021 ◽  
Vol 18 (2) ◽  
pp. 476
Author(s):  
Bum Jung Kim ◽  
Sun-young Lee
Keyword(s):  
Social Support ◽  
Long Term Care ◽  
Cross Sectional Study ◽  
Care Staff ◽  
Hierarchical Regression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Term Care ◽  
The Impact

Extensive research has demonstrated the factors that influence burnout among social service employees, yet few studies have explored burnout among long-term care staff in Hawaii. This study aimed to examine the impact of job value, job maintenance, and social support on burnout of staff in long-term care settings in Hawaii, USA. This cross-sectional study included 170 long-term care staff, aged 20 to 75 years, in Hawaii. Hierarchical regression was employed to explore the relationships between the key independent variables and burnout. The results indicate that staff with a higher level of perceived job value, those who expressed a willingness to continue working in the same job, and those with strong social support from supervisors or peers are less likely to experience burnout. Interventions aimed at decreasing the level of burnout among long-term care staff in Hawaii may be more effective through culturally tailored programs aimed to increase the levels of job value, job maintenance, and social support.

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