scholarly journals Physicochemical Properties of the Soluble Dietary Fiber from Laminaria japonica and Its Role in the Regulation of Type 2 Diabetes Mice

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 329
Author(s):  
Xixi Wang ◽  
Liping Zhang ◽  
Ling Qin ◽  
Yanfeng Wang ◽  
Fushan Chen ◽  
...  

Laminaria japonica is a large marine brown alga that is annually highly productive. However, due to its underutilization, its potential value is substantially wasted. For example, a lot of Laminaria japonica cellulose remains unused during production of algin. The soluble dietary fiber (SDF) was prepared from the byproducts of Laminaria japonica, and its physicochemical properties were explored. SDF exhibits good water-holding, oil-holding, water-absorbing swelling, glucose and cholesterol absorption capacity, and inhibitory activity of α-amylase and α-glucosidase. In addition, the beneficial effects of SDF in diabetic mice include reduced body weight, lower blood glucose, and relieved insulin resistance. Finally, the intestinal flora and metabolomic products were analyzed from feces using 16S amplicon and LC-MS/MS, respectively. SDF not only significantly changed the composition and structure of intestinal flora and intestinal metabolites, but also significantly increased the abundance of beneficial bacteria Akkermansia, Odoribacter and Bacteroides, decreased the abundance of harmful bacteria Staphylococcus, and increased the content of bioactive substances in intestinal tract, such as harmine, magnolol, arachidonic acid, prostaglandin E2, urimorelin and azelaic acid. Taken together, these findings suggest that dietary intake of SDF alleviates type 2 diabetes mellitus disease, and provides an important theoretical basis for SDF to be used as a functional food.

Food Research ◽  
2020 ◽  
Vol 4 (3) ◽  
pp. 722-730
Author(s):  
Nurul Hakimah ◽  
Mahmud Yunus ◽  
Sucipto Sucipto ◽  
Wignyanto Wignyanto ◽  
Aulanni'am Aulanni'am

This study was aimed to examine energy, density, proximate, dietary fiber and macronutrients ratio on the glycemic index and glycemic load of 6 kinds Indonesian local package menus made of red rice as a staple food and several other potentially antidiabetic food ingredients. The design was a quasi-experimental with 20 participants each of which were10 non-diabetic subjects (4 males and 6 females) aged between 20.3±1.0 years old and 10 subjects with type 2 diabetes (5 males and 5 females) aged between 54.4±9.3 years old. The results showed test package menu 1 (nasi liwet) has glycemic index and glycemic load can be accepted as healthy menu package in both, non-diabetic subjects (glycemic index = 23.8±9.2; glycemic load = 11.9±4.6) and diabetes subjects (glycemic index = 17.5±8.5; glycemic load = 8.7±3.3). There is a moderate to a strong negative correlation between glycemic index and the incremental area under the curve with the content of protein, fat, total dietary fiber, soluble dietary fiber, and moderate to strong positive correlation with macronutrients ratio. In conclusion, prevention of increased postprandial blood glucose in the management of type 2 diabetes mellitus diet can be done by preparing a local Indonesian menu package based on red rice food ingredients by considering the type of menu, protein, fat, total and soluble dietary fiber, and macronutrient ratio.


2016 ◽  
Vol 12 (2) ◽  
pp. 1232-1242 ◽  
Author(s):  
Chunye Chen ◽  
Yuan Zeng ◽  
Jing Xu ◽  
Hongting Zheng ◽  
Jun Liu ◽  
...  

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 227-OR
Author(s):  
FLAVIA TRAMONTANA ◽  
ERNESTO MADDALONI ◽  
SARA GRECI ◽  
GIUSEPPE DEFEUDIS ◽  
ROCKY STROLLO ◽  
...  

2009 ◽  
Vol 74 (8) ◽  
pp. C628-C636 ◽  
Author(s):  
Min Zhang ◽  
Yi Liang ◽  
Ying Pei ◽  
Weiwei Gao ◽  
Zesheng Zhang

2016 ◽  
Vol 62 (6) ◽  
pp. 416-424
Author(s):  
Kazuhiro KUBO ◽  
Ayano KOIDO ◽  
Misako KITANO ◽  
Hirotaka YAMAMOTO ◽  
Morio SAITO

Author(s):  
Ellen E. Blaak ◽  

This chapter reviews how dietary fibers can be used to prevent Type 2 diabetes mellitus. Dietary fibers are a heterogenous group of food compounds. The physicochemical properties of dietary fibers determine their effects on gastrointestinal and metabolic health, including effect on gastro-intestinal transit, glycemic response, microbial composition and fermentative capacity. Most fiber rich foods contain insoluble, prebiotic and viscous fibers in varying ratios. The chapter begins by discussing underlying mechanisms of action of insoluble fibers. It then goes on to discuss the various dietary fiber intervention studies, specifically focusing on prebiotic fibers and soluble viscous fibers. The chapter concludes by highlighting the importance of consuming high levels dietary fiber and whole grains and their positive impact on metabolic health.


2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Yotsapon Thewjitcharoen ◽  
Phawinpon Chotwanvirat ◽  
Annapann Jantawan ◽  
Nantaporn Siwasaranond ◽  
Sunee Saetung ◽  
...  

Introduction. Most nutritional guidelines for diabetes management emphasize the importance of having individualized goals, away from a one-size-fits-all approach. However, there is a dearth of information on the dietary intakes and nutritional knowledge of Thai patients with type 2 diabetes mellitus (T2DM). This study is aimed at clarifying dietary intakes in relationship to glycemic control and at examining nutritional knowledge among Thai patients with T2DM. Materials and Methods. A cross-sectional study of outpatients with T2DM at Theptarin Hospital and Ramathibodi Hospital (Bangkok, Thailand) was performed to assess dietary intakes by food records. Diabetes nutritional knowledge and dietary self-care behavior was also evaluated. Results. A total of 304 Thai patients with T2DM (female 52.6%, mean age 57.4 ± 10.9 years, body mass index (BMI) 27.3 ± 4.8 kg/m2, and baseline A1C 7.2 ± 1.3%) participated in the study. The mean daily calorie intake was 1427 ± 425 kcal, and mean intake for each macronutrient was acceptable (carbohydrate 52%, protein 17%, and fat 31%). However, the intake of free sugar was much higher (12.1 ± 5.8% of total daily energy intake) and dietary fiber intake (9 grams per day) was much lower than recommended. There were no correlations between dietary intake and glycemic control. A subset of patients (N=213) completed the diabetes nutritional knowledge survey. There was no association between diabetes nutritional knowledge and the actual dietary self-care behavior. Conclusion. These results indicate that compliance of Thai patients with T2DM to dietary recommendations is not completely satisfactory, especially for free sugar and dietary fiber intakes. Addressing the reality of how patients with T2DM eat in their daily lives and their knowledge gaps would enable them to adhere to medical nutrition therapy.


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