Association of Nut Consumption with Cardiometabolic Risk Factors in the 2008/2009 New Zealand Adult Nutrition Survey

Studies investigating the associations between dietary glycemic index (GI) and glycemic load (GL) values and cardiometabolic risk factors (CMRF) among Chinese populations are strikingly limited. To assess the associations between dietary GI and GL values and CMRF, including dyslipidemia, hyperglycemia, and hyperuricemia in Chinese adults, we extracted data of 7886 apparently healthy adults from the 2009 wave of the China Health and Nutrition Survey. Dietary GI and GL values were calculated using data collected from three consecutive 24 h dietary recalls. Fasting lipid, glucose, and uric acid concentrations were measured and CMRF were defined on the basis of established criteria. There were no significant associations between dietary GI values and CMRF, and analyzing the data by age, sex, body mass index (BMI), and region did not alter these results. Dietary GL values were positively associated with prevalence of hyperuricemia in all participants (Q4 compared with Q1: odds ratio (OR) = 1.46; 95% CI: 1.14, 1.87; p-trend = 0.0030) and prevalence of hypercholesterolemia in participants ≥ 60 years old (Q5 compared with Q1: OR = 1.72; 95% CI: 1.11, 2.68; p-trend < 0.0010). Higher dietary GL but not GI values were associated with increased prevalence of hyperuricemia in apparently healthy Chinese adults and hypercholesterolemia in older Chinese adults. Further studies are required to confirm the public health implication of these findings.

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Association of Free Sugars Intake with Cardiometabolic Risk Factors among Japanese Adults: The 2016 National Health and Nutrition Survey, Japan

Nutrients ◽

10.3390/nu12123624 ◽

2020 ◽

Vol 12 (12) ◽

pp. 3624

Author(s):

Aya Fujiwara ◽

Emiko Okada ◽

Chika Okada ◽

Mai Matsumoto ◽

Hidemi Takimoto

Keyword(s):

Risk Factors ◽

Cholesterol Level ◽

Cardiometabolic Risk ◽

Density Lipoprotein ◽

Hdl Cholesterol ◽

Cardiometabolic Risk Factors ◽

Nutrition Survey ◽

Free Sugars ◽

Health And Nutrition ◽

Japanese Adults

The relationship between free sugars intake and cardiometabolic risk factors is unclear in Japanese adults. This cross-sectional study aimed to investigate this association using data from the 2016 National Health and Nutrition Survey, Japan. The percentage of energy intake from free sugars was estimated based on the 1-day weighed dietary record data of Japanese men (n = 4071) and women (n = 5794) aged ≥ 20 years. Associations between free sugars intake and cardiometabolic risk factors, including body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressures, glycated haemoglobin (HbA1c) level and levels of serum total, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol, were investigated using linear regression and Dunnett’s test, with the lowest category of quartiles as a reference. After adjustment for potential confounding factors, free sugars intake was inversely associated with blood pressures (men only) and HDL-cholesterol level (both sexes) and positively associated with total-cholesterol level (women only) and LDL-cholesterol level (both sexes), whereas no association was observed for BMI, WC, and HbA1c level. This study identified both positive and inverse associations of free sugars intake with cardiometabolic risk factors in Japanese adults.

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Abstract P089: Fitness and Fatness Are Both Associated With Cardiometabolic Health in 8-10 Year Old New Zealand Children

Circulation ◽

10.1161/circ.137.suppl_1.p089 ◽

2018 ◽

Vol 137 (suppl_1) ◽

Author(s):

Lee Stoner ◽

Nicholas Castro ◽

Paula Skidmore ◽

Sally Lark ◽

James Faulkner ◽

...

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

New Zealand ◽

Carbohydrate Metabolism ◽

Cardiometabolic Risk ◽

Cumulative Risk ◽

Cardiometabolic Risk Factors ◽

Cardiometabolic Health ◽

Metabolic Risk ◽

High Fitness

Introduction: In adults, low cardiorespiratory fitness (CRF) and overweight-obesity are associated with greater cardiometabolic disease risk. However, the association between measures of CRF and overweight-obesity upon cardiometabolic risk in youth, particularly pre-adolescents, is less clear. Further, previous studies in children have predominantly examined the relationships between CRF and overweight-obesity upon individual cardiometabolic risk factors. The clustering of cardiometabolic risk factors has been recognized for over two decades, including in young children. Hypothesis: We tested the null hypothesis of no association between clustered cardiometabolic risk factors and high CRF or overweight-obesity. Methods: This cross-sectional study recruited 392 children (50% F) aged 8-10 years from three representative sample sites across New Zealand. Overweight-obesity was classified according to 2007 WHO criteria for Body Mass Index. CRF was estimated using a shuttle run test, and high CRF was categorized as a maximum oxygen uptake exceeding 35 ml/kg/min in girls, and 42 ml/kg/min in boys. Eleven traditional and novel cardiometabolic risk factors were measured: peripheral blood pressures, central systolic blood pressure, heart rate, augmentation index, fasting total cholesterol, high density lipoproteins, low density lipoproteins, triglycerides, serum glucose, and glycosylated haemoglobin. Principal component analysis identified underlying cardio-metabolic factors, and a 2-way (high fitness, overweight-obese) analysis of co-variance was used to determine associations between cardio-metabolic risk factors with fitness and overweight-obesity. Covariates were: age, sex, ethnicity, socio-economic status. Results: Principle component analysis revealed four underling factors: blood pressure, cholesterol, vascular, and carbohydrate-metabolism. Using these factors, a cumulative risk score was also calculated. Only high CRF (P=0.001, Eta=0.028) was significantly associated with the blood pressure factor. Only overweight-obesity associated with vascular (P=0.010, Eta=0.018) and carbohydrate-metabolism (P=0.005, Eta=0.021) factors. Neither high fitness (p=0.728) nor overweight-obesity (P=0.121) significantly associated with cholesterol. For the cumulative risk score, there was an interaction effect (P=0.038, Eta=0.012). High CRF improved cardiometabolic risk in overweight-obese children (P=0.006, Eta=0.02), but not in normal weight children. Conversely, being overweight-obese increased cardiometabolic health risk in children with low fat levels (P<0.001, Eta=0.039), but not in high fit children. Conclusions: In pre-adolescent children, fitness and fatness associate with different cardio-metabolic risk. With regards to overall cardio-metabolic risk, high fitness may protect against overweight-obesity.

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Association of free sugars intake with cardiometabolic risk factors among Japanese adults: the 2016 National Health and Nutrition Survey, Japan

10.26226/morressier.5fb3ba674d4e91fe5c54bc9e ◽

2020 ◽

Author(s):

Aya Fujiwara

Keyword(s):

Risk Factors ◽

National Health ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Nutrition Survey ◽

Free Sugars ◽

Health And Nutrition ◽

Japanese Adults

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P1849ANALYSIS OF ASSOCIATION BETWEEN URBANIZATION AND REDUCED RENAL FUNCTION IN INDIAN POPULATION

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfaa142.p1849 ◽

2020 ◽

Vol 35 (Supplement_3) ◽

Author(s):

Rahul Kumar

Keyword(s):

Risk Factors ◽

Renal Function ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Health Concern ◽

Nutrition Survey ◽

Creatinine Concentration ◽

Middle Income ◽

Multilevel Logistic Model ◽

Reduced Renal Function

Abstract Background and Aims While chronic kidney disease (CKD) is a growing public health concern in low- and middle-income countries, such as India, few studies have investigated the association between urbanization and the occurrence of CKD in those countries. METHODS We investigated the association between urbanization and estimated glomerular filtration rate (eGFR), an important CKD risk marker. Data came from the India Health and Nutrition Survey wave 2017, in which we collected fasting serum, individual and household data along with community level urbanization data, which was used to derive a study-specific urbanization measure, in 218 communities across fifteen states. A total of 8754 men and 8566 women participants aged 18 years or older were included in the analysis. Reduced renal function was defined as eGFR of less than 60 mL/min/1.73 m2 measured using serum creatinine concentration (mg/dL). RESULTS After adjusting for socio-demographic (e.g., age, education and household income), a sex-stratified multilevel logistic model revealed that living in a more urbanized community was associated with higher odds of reduced eGFR (odds ratio [OR] = 1.38 per one-standard deviation [SD] increase in the CHNS specific urbanization index, 95% confidence interval [CI] = 1.11-1.73 for men; OR = 1.35, 95% CI = 1.11-1.62 for women). After adjusting for behavioral variables (i.e., alcohol consumption, smoking, physical activity and diet), as well as obesity and cardiometabolic risk factors, the association was attenuated in men (OR = 1.25, 95% CI = 0.98-1.59), but remained statistically significant in women (OR = 1.24, 95% CI = 1.01-1.52). CONCLUSION Our findings suggest that living in an urban environment is linked with higher odds of reduced renal function independently of behavioral and cardiometabolic risk factors, which have been shown to increase along with urbanization.

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TyG Index Distributions and Relationship to Cardiometabolic Risk Factors in Children and Adolescents: A Population-Based Study

10.21203/rs.3.rs-721138/v1 ◽

2021 ◽

Author(s):

Jong Seo Yoon ◽

Young Suk Shim ◽

Hae Sang Lee ◽

Il Tae Hwang ◽

Jin Soon Hwang

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Children And Adolescents ◽

Cardiometabolic Risk ◽

Linear Regression Analysis ◽

Standard Deviation Score ◽

Cardiometabolic Risk Factors ◽

Multivariate Linear Regression Analysis ◽

Nutrition Survey ◽

Tyg Index

Abstract The purpose of this study was to present age- and sex-specific distributions of the triglyceride-glucose (TyG) index and to evaluate their relationship with cardiometabolic risk factors in children and adolescents. A total of 7,404 participants aged 10–18 years from the Korean National Health and Nutrition Survey were included as the reference population. The TyG index was calculated as ln(fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). The percentile of the TyG index exhibited a steady linear relationship with age for both sexes. TyG index significantly correlated with waist circumference (WC) standard deviation score (SDS; r = 0.110, p < 0.001), systolic blood pressure (SBP; r = 0.104, p < 0.001), diastolic blood pressure (DBP; r = 0.083, p < 0.001), glucose (r = 0.220, p < 0.001), high-density lipoprotein cholesterol (HDL-C; r=-0.325, p < 0.001), and triglycerides (TG; r = 0.926, p < 0.001). Multivariate linear regression analysis revealed that the TyG index was significantly associated with WC SDS (β = 0.116, p < 0.001), SBP (β = 2.009, p < 0.001), DBP (β = 1.464, p < 0.001), glucose (β = 3.376, p < 0.001), HDL-C (β=−6.431, p < 0.001), and TG (β = 85.518, p < 0.001). Our results suggest that the TyG index has a steady linear distribution for sex and age in children and adolescents and constitutes an indicator for predicting metabolic disorders that could lead to cardiovascular disease later in life.

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A population-based study of TyG index distribution and its relationship to cardiometabolic risk factors in children and adolescents

Scientific Reports ◽

10.1038/s41598-021-03138-6 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Jong Seo Yoon ◽

Young Suk Shim ◽

Hae Sang Lee ◽

Il Tae Hwang ◽

Jin Soon Hwang

Keyword(s):

Risk Factors ◽

Blood Pressure ◽

Children And Adolescents ◽

Cardiometabolic Risk ◽

Linear Regression Analysis ◽

Standard Deviation Score ◽

Cardiometabolic Risk Factors ◽

Nutrition Survey ◽

Linear Distribution ◽

Tyg Index

AbstractThe purpose of this study was to present age- and sex-specific distributions of the triglyceride-glucose (TyG) index and to evaluate their relationship with cardiometabolic risk factors in children and adolescents. A total of 7404 participants aged 10–18 years from the Korean National Health and Nutrition Survey were included as the reference population. The TyG index was calculated as ln(fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). The percentile of the TyG index exhibited a steady linear relationship with age for both sexes. TyG index significantly correlated with waist circumference (WC) standard deviation score (SDS; r = 0.110, p < 0.001), systolic blood pressure (SBP; r = 0.104, p < 0.001), diastolic blood pressure (DBP; r = 0.083, p < 0.001), glucose (r = 0.220, p < 0.001), high-density lipoprotein cholesterol (HDL-C; r = − 0.325, p < 0.001), and triglycerides (TG; r = 0.926, p < 0.001). Multiple linear regression analysis revealed that the TyG index was significantly associated with WC SDS (β = 0.116, p < 0.001), SBP (β = 2.009, p < 0.001), DBP (β = 1.464, p < 0.001), glucose (β = 3.376, p < 0.001), HDL-C (β = − 6.431, p < 0.001), and TG (β = 85.518, p < 0.001). Our results suggest that the TyG index has a steady linear distribution for sex and age in children and adolescents and constitutes an indicator for predicting metabolic disorders that could lead to cardiovascular disease later in life.

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Low-Calorie Beverage Consumption, Diet Quality and Cardiometabolic Risk Factors in British Adults

Nutrients ◽

10.3390/nu10091261 ◽

2018 ◽

Vol 10 (9) ◽

pp. 1261 ◽

Cited By ~ 5

Author(s):

Linia Patel ◽

Gianfranco Alicandro ◽

Carlo La Vecchia

Keyword(s):

Risk Factors ◽

Energy Intake ◽

Diet Quality ◽

Cardiometabolic Risk ◽

Cardiometabolic Risk Factors ◽

Free Sugar ◽

Nutrition Survey ◽

Low Calorie ◽

Sugar Intake ◽

The Uk

Low-calorie beverages (LCBs) are promoted as healthy alternatives to sugar-sweetened beverages (SSBs); however, their effects on diet quality and cardiometabolic profile are debatable. This study aimed to verify the association between LCB consumption, diet quality and cardiometabolic risk factors in British adults. Data analysis from 5521 subjects aged 16 and older who participated in two waves of the National Diet and Nutrition Survey Rolling Programme (2008–2012 and 2013–2014) was carried out. Compared with SSB consumption, LCB consumption was associated with lower energy (mean difference: −173 kcal, 95% confidence interval, CI: −212; −133) and free sugar intake (−5.6% of energy intake, 95% CI: −6.1; −5.1), while intake of other nutrients was not significantly different across groups. The % difference in sugar intake was more pronounced among the young (16–24 years) (−7.3 of energy intake, 95% CI: −8.6; −5.9). The odds of not exceeding the UK-recommended free sugar intake were remarkably higher in the LCB as compared to the SSB group (OR: 9.4, 95% CI: 6.5–13.6). No significant differences were observed in plasma glucose, total cholesterol, LDL, HDL or triglycerides. Our findings suggest that LCBs are associated with lower free sugar intake without affecting the intake of other macronutrients or negatively impacting cardiometabolic risk factors.

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Associations between Dietary Animal and Plant Protein Intake and Cardiometabolic Risk Factors—A Cross-Sectional Study in China Health and Nutrition Survey

Nutrients ◽

10.3390/nu13020336 ◽

2021 ◽

Vol 13 (2) ◽

pp. 336

Author(s):

Shuangli Meng ◽

Zhixin Cui ◽

Minjuan Li ◽

Ting Li ◽

Feng Wu ◽

...

Keyword(s):

Risk Factors ◽

Uric Acid ◽

Energy Intake ◽

Cardiometabolic Risk ◽

Density Lipoprotein ◽

Cardiometabolic Risk Factors ◽

Plant Protein ◽

Lipoprotein Cholesterol ◽

Nutrition Survey ◽

Health And Nutrition

Available data investigating the associations between dietary animal and plant protein intakes and cardiometabolic risk factors (CMRFs) among populations with habitual plant-based diets are heterogenous and limited in scope. The current study was to assess the associations between dietary animal and plant protein intakes and CMRFs, including lipid and lipoprotein profiles, glucose homeostasis biomarkers, low-grade chronic inflammatory biomarker and uric acid in Chinese adults. Data of 7886 apparently healthy adults were extracted from the China Health and Nutrition Survey 2009. Dietary protein (total, animal and plant) intakes were assessed with three consecutive 24 h dietary recalls, and CMRFs were measured with standard laboratory methods. Substituting 5% of energy intake from animal protein for carbohydrates was positively associated with total cholesterol, low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C) and uric acid (all p < 0.05). Substituting 5% of energy intake from plant protein for carbohydrates was inversely associated with non-HDL-C and LDL-C:HDL-C ratio, and positively associated with HDL-C and glycated hemoglobin (all p < 0.05). Some of these associations varied in subgroup analyses by BMI, sex, age or region. There were no significant associations between animal or plant protein intakes and high-sensitivity C-reactive protein. The public health implication of these findings requires further investigation.

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