scholarly journals P1849ANALYSIS OF ASSOCIATION BETWEEN URBANIZATION AND REDUCED RENAL FUNCTION IN INDIAN POPULATION

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Rahul Kumar

Abstract Background and Aims While chronic kidney disease (CKD) is a growing public health concern in low- and middle-income countries, such as India, few studies have investigated the association between urbanization and the occurrence of CKD in those countries. METHODS We investigated the association between urbanization and estimated glomerular filtration rate (eGFR), an important CKD risk marker. Data came from the India Health and Nutrition Survey wave 2017, in which we collected fasting serum, individual and household data along with community level urbanization data, which was used to derive a study-specific urbanization measure, in 218 communities across fifteen states. A total of 8754 men and 8566 women participants aged 18 years or older were included in the analysis. Reduced renal function was defined as eGFR of less than 60 mL/min/1.73 m2 measured using serum creatinine concentration (mg/dL). RESULTS After adjusting for socio-demographic (e.g., age, education and household income), a sex-stratified multilevel logistic model revealed that living in a more urbanized community was associated with higher odds of reduced eGFR (odds ratio [OR] = 1.38 per one-standard deviation [SD] increase in the CHNS specific urbanization index, 95% confidence interval [CI] = 1.11-1.73 for men; OR = 1.35, 95% CI = 1.11-1.62 for women). After adjusting for behavioral variables (i.e., alcohol consumption, smoking, physical activity and diet), as well as obesity and cardiometabolic risk factors, the association was attenuated in men (OR = 1.25, 95% CI = 0.98-1.59), but remained statistically significant in women (OR = 1.24, 95% CI = 1.01-1.52). CONCLUSION Our findings suggest that living in an urban environment is linked with higher odds of reduced renal function independently of behavioral and cardiometabolic risk factors, which have been shown to increase along with urbanization.

Nutrients ◽  
2020 ◽  
Vol 13 (1) ◽  
pp. 116
Author(s):  
Minjuan Li ◽  
Zhixin Cui ◽  
Shuangli Meng ◽  
Ting Li ◽  
Tong Kang ◽  
...  

Studies investigating the associations between dietary glycemic index (GI) and glycemic load (GL) values and cardiometabolic risk factors (CMRF) among Chinese populations are strikingly limited. To assess the associations between dietary GI and GL values and CMRF, including dyslipidemia, hyperglycemia, and hyperuricemia in Chinese adults, we extracted data of 7886 apparently healthy adults from the 2009 wave of the China Health and Nutrition Survey. Dietary GI and GL values were calculated using data collected from three consecutive 24 h dietary recalls. Fasting lipid, glucose, and uric acid concentrations were measured and CMRF were defined on the basis of established criteria. There were no significant associations between dietary GI values and CMRF, and analyzing the data by age, sex, body mass index (BMI), and region did not alter these results. Dietary GL values were positively associated with prevalence of hyperuricemia in all participants (Q4 compared with Q1: odds ratio (OR) = 1.46; 95% CI: 1.14, 1.87; p-trend = 0.0030) and prevalence of hypercholesterolemia in participants ≥ 60 years old (Q5 compared with Q1: OR = 1.72; 95% CI: 1.11, 2.68; p-trend < 0.0010). Higher dietary GL but not GI values were associated with increased prevalence of hyperuricemia in apparently healthy Chinese adults and hypercholesterolemia in older Chinese adults. Further studies are required to confirm the public health implication of these findings.


2019 ◽  
Vol 287 ◽  
pp. e283-e284
Author(s):  
N. Kovalkova ◽  
Y. Ragino ◽  
D. Denisova ◽  
L. Scherbakova ◽  
M. Voevoda

Nutrients ◽  
2020 ◽  
Vol 12 (12) ◽  
pp. 3624
Author(s):  
Aya Fujiwara ◽  
Emiko Okada ◽  
Chika Okada ◽  
Mai Matsumoto ◽  
Hidemi Takimoto

The relationship between free sugars intake and cardiometabolic risk factors is unclear in Japanese adults. This cross-sectional study aimed to investigate this association using data from the 2016 National Health and Nutrition Survey, Japan. The percentage of energy intake from free sugars was estimated based on the 1-day weighed dietary record data of Japanese men (n = 4071) and women (n = 5794) aged ≥ 20 years. Associations between free sugars intake and cardiometabolic risk factors, including body mass index (BMI), waist circumference (WC), systolic and diastolic blood pressures, glycated haemoglobin (HbA1c) level and levels of serum total, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol, were investigated using linear regression and Dunnett’s test, with the lowest category of quartiles as a reference. After adjustment for potential confounding factors, free sugars intake was inversely associated with blood pressures (men only) and HDL-cholesterol level (both sexes) and positively associated with total-cholesterol level (women only) and LDL-cholesterol level (both sexes), whereas no association was observed for BMI, WC, and HbA1c level. This study identified both positive and inverse associations of free sugars intake with cardiometabolic risk factors in Japanese adults.


2019 ◽  
Vol 91 (1) ◽  
pp. 64-70 ◽  
Author(s):  
N A Kovalkova ◽  
Yu I Ragino ◽  
L V Scherbakova ◽  
A D Hudyakova ◽  
D V Denisova ◽  
...  

Aim. To study relationships of reduced renal function with hypertension and other cardiometabolic risk factors in persons aged 25-45 years. Materials and methods. A cross-sectional population study of one of the typical district of Novosibirsk (Russia) was performed during 2013-2016 years. The study included 468 men and 606 women aged 25-45 years. Blood pressure (BP), waist circumference (WC), blood lipids, glucose, creatinine were measured. Glomerular filtration rate (GFR) was calculated with the formula CKD-EPI. Hypertension was registered if blood pressure (BP) was ≥140/90 mm Hg, reduced kidney function - at GFR


Author(s):  
Ignatius H. Sirikyi ◽  
Sebastian Eliason ◽  
Frank N. Ghartey ◽  
Evans Ekenam ◽  
Kingsley K. A. Pereko ◽  
...  

AbstractObjectivesAdolescent overweight and obesity is a public health concern globally, especially in lower- and middle- income countries where there is an additional burden of undernutrition. The prevalence of adolescent overweight/2obesity has increased markedly over the past three decades. The transition in dietary habits coupled with reduced physical activity has been blamed for the increasing trend. Overweight/obesity in adolescence is complicated by cardiometabolic, respiratory, musculoskeletal and psychosocial disorders. Additionally, adolescent obesity is a predictor of future development of type 2 diabetes, cardiovascular diseases and metabolic disorders. The burden of cardiometabolic risk factors associated with adolescent overweight/obesity in Ghana is lacking, the project, therefore, was undertaken to add to the existing knowledge.MethodsThe study was undertaken in adolescent students of a tertiary institution in Ghana. Two hundred and one students consented to participate in the study. Questionnaires on sociodemographic characteristics, dietary and substance abuse habits were self-administered. Blood pressure, height, weight and waist circumference measures were performed and venous blood drawn for the determination of fasting serum total/LDL/HDL cholesterol and triglycerides. Body mass indices were determined as the weight per square of their heights.ResultsThe prevalence of obesity was determined to be 15.81% generally, 27.71% in the females and 7.08% in the males. Diastolic blood pressure was the only cardiometabolic risk factor significantly associated with obesity in our study.ConclusionOverweight/obesity is common in Ghanaian adolescents, with the prevalence highest in the female population.


2021 ◽  
Author(s):  
Jong Seo Yoon ◽  
Young Suk Shim ◽  
Hae Sang Lee ◽  
Il Tae Hwang ◽  
Jin Soon Hwang

Abstract The purpose of this study was to present age- and sex-specific distributions of the triglyceride-glucose (TyG) index and to evaluate their relationship with cardiometabolic risk factors in children and adolescents. A total of 7,404 participants aged 10–18 years from the Korean National Health and Nutrition Survey were included as the reference population. The TyG index was calculated as ln(fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). The percentile of the TyG index exhibited a steady linear relationship with age for both sexes. TyG index significantly correlated with waist circumference (WC) standard deviation score (SDS; r = 0.110, p < 0.001), systolic blood pressure (SBP; r = 0.104, p < 0.001), diastolic blood pressure (DBP; r = 0.083, p < 0.001), glucose (r = 0.220, p < 0.001), high-density lipoprotein cholesterol (HDL-C; r=-0.325, p < 0.001), and triglycerides (TG; r = 0.926, p < 0.001). Multivariate linear regression analysis revealed that the TyG index was significantly associated with WC SDS (β = 0.116, p < 0.001), SBP (β = 2.009, p < 0.001), DBP (β = 1.464, p < 0.001), glucose (β = 3.376, p < 0.001), HDL-C (β=−6.431, p < 0.001), and TG (β = 85.518, p < 0.001). Our results suggest that the TyG index has a steady linear distribution for sex and age in children and adolescents and constitutes an indicator for predicting metabolic disorders that could lead to cardiovascular disease later in life.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jong Seo Yoon ◽  
Young Suk Shim ◽  
Hae Sang Lee ◽  
Il Tae Hwang ◽  
Jin Soon Hwang

AbstractThe purpose of this study was to present age- and sex-specific distributions of the triglyceride-glucose (TyG) index and to evaluate their relationship with cardiometabolic risk factors in children and adolescents. A total of 7404 participants aged 10–18 years from the Korean National Health and Nutrition Survey were included as the reference population. The TyG index was calculated as ln(fasting triglyceride [mg/dL] × fasting glucose [mg/dL]/2). The percentile of the TyG index exhibited a steady linear relationship with age for both sexes. TyG index significantly correlated with waist circumference (WC) standard deviation score (SDS; r = 0.110, p < 0.001), systolic blood pressure (SBP; r = 0.104, p < 0.001), diastolic blood pressure (DBP; r = 0.083, p < 0.001), glucose (r = 0.220, p < 0.001), high-density lipoprotein cholesterol (HDL-C; r = − 0.325, p < 0.001), and triglycerides (TG; r = 0.926, p < 0.001). Multiple linear regression analysis revealed that the TyG index was significantly associated with WC SDS (β = 0.116, p < 0.001), SBP (β = 2.009, p < 0.001), DBP (β = 1.464, p < 0.001), glucose (β = 3.376, p < 0.001), HDL-C (β =  − 6.431, p < 0.001), and TG (β = 85.518, p < 0.001). Our results suggest that the TyG index has a steady linear distribution for sex and age in children and adolescents and constitutes an indicator for predicting metabolic disorders that could lead to cardiovascular disease later in life.


Nutrients ◽  
2018 ◽  
Vol 10 (9) ◽  
pp. 1261 ◽  
Author(s):  
Linia Patel ◽  
Gianfranco Alicandro ◽  
Carlo La Vecchia

Low-calorie beverages (LCBs) are promoted as healthy alternatives to sugar-sweetened beverages (SSBs); however, their effects on diet quality and cardiometabolic profile are debatable. This study aimed to verify the association between LCB consumption, diet quality and cardiometabolic risk factors in British adults. Data analysis from 5521 subjects aged 16 and older who participated in two waves of the National Diet and Nutrition Survey Rolling Programme (2008–2012 and 2013–2014) was carried out. Compared with SSB consumption, LCB consumption was associated with lower energy (mean difference: −173 kcal, 95% confidence interval, CI: −212; −133) and free sugar intake (−5.6% of energy intake, 95% CI: −6.1; −5.1), while intake of other nutrients was not significantly different across groups. The % difference in sugar intake was more pronounced among the young (16–24 years) (−7.3 of energy intake, 95% CI: −8.6; −5.9). The odds of not exceeding the UK-recommended free sugar intake were remarkably higher in the LCB as compared to the SSB group (OR: 9.4, 95% CI: 6.5–13.6). No significant differences were observed in plasma glucose, total cholesterol, LDL, HDL or triglycerides. Our findings suggest that LCBs are associated with lower free sugar intake without affecting the intake of other macronutrients or negatively impacting cardiometabolic risk factors.


Nutrients ◽  
2015 ◽  
Vol 7 (9) ◽  
pp. 7523-7542 ◽  
Author(s):  
Rachel Brown ◽  
Siew Tey ◽  
Andrew Gray ◽  
Alexandra Chisholm ◽  
Claire Smith ◽  
...  

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