scholarly journals Polymeric Carriers Designed for Encapsulation of Essential Oils with Biological Activity

Pharmaceutics ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 631
Author(s):  
Aurica P. Chiriac ◽  
Alina G. Rusu ◽  
Loredana E. Nita ◽  
Vlad M. Chiriac ◽  
Iordana Neamtu ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Biological Activity ◽  
Controlled Release ◽  
Essential Oils ◽  
Environmental Conditions ◽  
Natural Polymers ◽  
Polymeric Carriers ◽  
Potential Applicability ◽  
Encapsulation Methods

The article reviews the possibilities of encapsulating essential oils EOs, due to their multiple benefits, controlled release, and in order to protect them from environmental conditions. Thus, we present the natural polymers and the synthetic macromolecular chains that are commonly used as networks for embedding EOs, owing to their biodegradability and biocompatibility, interdependent encapsulation methods, and potential applicability of bioactive blend structures. The possibilities of using artificial intelligence to evaluate the bioactivity of EOs—in direct correlation with their chemical constitutions and structures, in order to avoid complex laboratory analyses, to save money and time, and to enhance the final consistency of the products—are also presented.

scholarly journals Variability in chemical composition and antimicrobial activity of essential oil of Rosa × damascena Herrm. from mountainous regions of Iran

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Mansureh Ghavam ◽  
Afsaneh Afzali ◽  
Maria Manconi ◽  
Gianluigi Bacchetta ◽  
Maria Letizia Manca
Keyword(s):  
Antimicrobial Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Essential Oils ◽  
Environmental Conditions ◽  
Raw Materials ◽  
Rosa Damascena ◽  
Mountainous Regions ◽  
Aspergillus Brasiliensis ◽  
Suitable Area

Abstract Background Essential oil of Rosa × damascena Herrm. is one of the most valuable and important raw materials for the flavor and fragrance industry. The cultivation of this plant has ancient origins, and Kashan was one of the first mountainous regions of Iran dealing with the cultivation of R. × damascena. In this study, both chemical composition and antimicrobial activity of different rose essential oils obtained from five mountainous areas of Kashan region (Maragh, Qamsar, Sadeh, Javinan, and Kamoo) has been investigated along with the influence of the environmental conditions on these properties. Results Results showed that yield and chemical composition of essential oils obtained from Rosa × damascena were significantly affected by the collection area. In particular, the yield of oils varied from ~0.08 to ~0.132% and citronellol (36.70-9.18%), geraniol (12.82-0.47%), nonadecane (22.73-10.36%), heneicosane (31.7-11.43%), and 1-nonadecene (6.03-3.93%) have been detected as main compounds in all the plants collected, but at different concentrations depending on the collection area. The best fragrance and the highest yield were found in the oil from Kamoo area. Similarly to the chemical composition, the antimicrobial activity of the essential oils was affected by their origin, and essential oil obtained from plants collected from Kamoo area disclosed the highest antibacterial and antifungal efficacy. Its inhibition halos were 17.33±0.58 mm against Aspergillus brasiliensis, 15.67±0.58 mm against Staphylococcus aureus, and 12.33±0. 58 mm against Streptococcus pyogenes. Essential oils of R. damascena were also effective against Gram-negative Pseudomonas aeruginosa and they had a MIC value of 62.50 μg/mL irrespective of the collection area (except the oil from Javinan area). On the contrary, the highest antifungal power against Candida albicans yeast was reached using the essential oil obtained from plants collected in Javinan region (MIC and MBC ~62.50 μg/mL). Conclusions Overall results underline the influence of environmental conditions of the different areas of Kashan region, on the chemical composition of and antimicrobial activity of the essential oils of Rosa × damascena. In addition, results disclosed that Kamoo seemed to be the most suitable area for the competitive cultivation of R. × damascena to the intensive production of aromatic flower oil and natural antimicrobial essential oils.

Preparation and Characterization of Drug-Loaded Thermosensitive Hydrogels

2013 ◽  
Author(s):  
L. Saeednia ◽  
A. Usta ◽  
R. Asmatulu
Keyword(s):  
Drug Delivery ◽  
Controlled Release ◽  
Body Temperature ◽  
Network Formation ◽  
Gelation Time ◽  
The Body ◽  
Antibacterial Drug ◽  
Natural Polymers ◽  
3D Network ◽  
Thermosensitive Hydrogels

Hydrogels are the promising classes of polymeric drug delivery systems with the controlled release rates. Among them, injectable thermosensitive hydrogels with transition temperature around the body temperature have been wildly considered. Chitosan is one of the most abundant natural polymers, and its biocompatibility and biodegradability makes it a favorable thermosensitive hydrogel that has been attracted much attention in biomedical field worldwide. In this work, a thermosensitive and injectable hydrogel was prepared using chitosan and β-glycerophosphate (β-GP) incorporated with an antibacterial drug (gentamycin). This drug loaded hydrogel is liquid at room temperature, and becomes more solidified gel when heated to the body temperature. Adding β-GP into chitosan and drug molecules and heating the overall solution makes the whole homogenous liquid into gel through a 3D network formation. The gelation time was found to be a function of temperature and concentration of β-GP. This thermosensitive chitosan based hydrogel system was characterized using FTIR and visual observation to determine the chemical structure and morphology. The results confirmed that chitosan/(β-GP) hydrogels could be a promising controlled-release drug delivery system for many deadly diseases.

Composition and Biological Activity of Essential Oils fromLippia origanoidesH.B.K.

2004 ◽  
Vol 16 (5) ◽  
pp. 504-506 ◽  
Author(s):  
Francisco J.B. dos Santos ◽  
J. Arimatéia D. Lopes ◽  
A. M. Graças L. Cito ◽  
Evaldo H. de Oliveira ◽  
Sidney G. de Lima ◽  
...  
Keyword(s):  
Biological Activity ◽  
Essential Oils

Optimization of Grease Dispensing Unit Using Fuzzy Logic Algorithm

2016 ◽  
Vol 852 ◽  
pp. 859-866
Author(s):  
Milind Havanur ◽  
A. Arockia Selvakumar
Keyword(s):  
Artificial Intelligence ◽  
Fuzzy Logic ◽  
Process Parameters ◽  
Environmental Conditions ◽  
Fuzzy Logic System ◽  
Automated System ◽  
Factors Affecting ◽  
Fuzzy Logic Algorithm ◽  
Optimal Quantity ◽  
Logic System

Grease dispensing unit is a well invented tool for greasing application which preserves health of operator working and ensures optimal quantity. There are fluctuations in the process of grease dispensing which is dependent on process parameters which make the grease dispensing. The properties of grease vary which depend on environmental conditions. In this paper the modeling of grease dispensing process using artificial intelligence method, fuzzy logic to optimize the flow of grease by considering the factors affecting the flow of grease and usage of automated system for grease dispensing process. The work involves usage of LabVIEW for modeling of fuzzy logic network Based on the results obtained a detailed discussions were made on how to implement the fuzzy logic system for optimization of flow of grease for the existing process. Further, the work also details the future scope of work that can be carried out.

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