scholarly journals Osteoconductive Effect of a Nanocomposite Membrane Treated with UV Radiation

Polymers ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 289
Author(s):  
Yusser Olguín ◽  
Soledad Acuna-Mendoza ◽  
Carolina Otero ◽  
Cristian A. Acevedo ◽  
Cristian Covarrubias

Modulation of the bio-regenerative characteristics of materials is an indispensable requirement in tissue engineering. Particularly, in bone tissue engineering, the promotion of the osteoconductive phenomenon determines the elemental property of a material be used therapeutically. In addition to the chemical qualities of the constituent materials, the three-dimensional surface structure plays a fundamental role that various methods are expected to modulate in a number of ways, one most promising of which is the use of different types of radiation. In the present manuscript, we demonstrate in a calvarial defect model, that treatment with ultraviolet irradiation allows modification of the osteoconductive characteristics in a biomaterial formed by gelatin and chitosan, together with the inclusion of hydroxyapatite and titanium oxide nanoparticles.

2020 ◽  
Vol 16 (4) ◽  
pp. 337-343
Author(s):  
Shaimaa E. Abdel-Ghany ◽  
Eman El-Sayed ◽  
Nour Ashraf ◽  
Nada Mokhtar ◽  
Amany Alqosaibi ◽  
...  

Background: Hepatocellular carcinoma is the second leading cause of cancer-related deaths among other types of cancer due to lack of effective treatments and late diagnosis. Nanocarriers represent a novel method to deliver chemotherapeutic drugs, enhancing their bioavailability and stability. Methods: In the present study, we loaded gold nanoparticles (AuNPs) and titanium oxide nanoparticles (TiO2NPs) with ERL to investigate the efficiency of the formed composite in inducing apoptosis in HepG2 liver cancer cells. Cytotoxicity was assessed using MTT assay and cell phase distribution was assessed by flow cytometry along with apoptosis detection. Results: Data obtained indicated the efficiency of the formed composite to significantly induce cell death and arrest cell cycle and G2/M phase. IRF4 was downregulated after treatment with loaded ERL. Conclusion: Our data showed that loading ERL on TiO2NPs was more efficient than AuNPs. However, both nanocarriers were efficient compared with control.


2016 ◽  
Vol 26 (2) ◽  
pp. 157-159 ◽  
Author(s):  
Ning Luo ◽  
Hong Wen Jing ◽  
Zhan Guo Ma ◽  
Weidong Liu ◽  
Liangchi Zhang ◽  
...  

2018 ◽  
Vol 55 (4) ◽  
pp. 616-619 ◽  
Author(s):  
Eugenia Eftimie Totu ◽  
Corina Marilena Cristache ◽  
Selim Isildak ◽  
Ozlem Tavukcuoglu ◽  
Aida Pantazi ◽  
...  

The present paper is focused on analyzing if appropriate adhesion between the polymeric matrix and titania filler nanoparticles is obtained for the PMMA-TiO2 photo-curable dental material, suitable for application in RP - stereolithography (SLA) for complete denture manufacturing. It was found that different amounts, between 0.2% and 2.5 % (w/w%), of added titanium oxide nanoparticles slightly modify the structural behavior of the PMMA polymeric matrix. The material characterization was carried out using FT-IR and microscopy techniques.


2015 ◽  
Vol 5 (0) ◽  
Author(s):  
Louis R. Hollingsworth ◽  
Joseph H. Conduff ◽  
Conner J. Balzer ◽  
Sieu K. Tran ◽  
Waqas Hamid ◽  
...  

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