scholarly journals A Critical Review of Electrochemical Glucose Sensing: Evolution of Biosensor Platforms Based on Advanced Nanosystems

Sensors ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 6013 ◽  
Author(s):  
Vuslat B. Juska ◽  
Martyn E. Pemble

The research field of glucose biosensing has shown remarkable growth and development since the first reported enzyme electrode in 1962. Extensive research on various immobilization methods and the improvement of electron transfer efficiency between the enzyme and the electrode have led to the development of various sensing platforms that have been constantly evolving with the invention of advanced nanostructures and their nano-composites. Examples of such nanomaterials or composites include gold nanoparticles, carbon nanotubes, carbon/graphene quantum dots and chitosan hydrogel composites, all of which have been exploited due to their contributions as components of a biosensor either for improving the immobilization process or for their electrocatalytic activity towards glucose. This review aims to summarize the evolution of the biosensing aspect of these glucose sensors in terms of the various generations and recent trends based on the use of applied nanostructures for glucose detection in the presence and absence of the enzyme. We describe the history of these biosensors based on commercialized systems, improvements in the understanding of the surface science for enhanced electron transfer, the various sensing platforms developed in the presence of the nanomaterials and their performances.

Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4672
Author(s):  
Mohamed H. Hassan ◽  
Cian Vyas ◽  
Bruce Grieve ◽  
Paulo Bartolo

The detection of glucose is crucial in the management of diabetes and other medical conditions but also crucial in a wide range of industries such as food and beverages. The development of glucose sensors in the past century has allowed diabetic patients to effectively manage their disease and has saved lives. First-generation glucose sensors have considerable limitations in sensitivity and selectivity which has spurred the development of more advanced approaches for both the medical and industrial sectors. The wide range of application areas has resulted in a range of materials and fabrication techniques to produce novel glucose sensors that have higher sensitivity and selectivity, lower cost, and are simpler to use. A major focus has been on the development of enzymatic electrochemical sensors, typically using glucose oxidase. However, non-enzymatic approaches using direct electrochemistry of glucose on noble metals are now a viable approach in glucose biosensor design. This review discusses the mechanisms of electrochemical glucose sensing with a focus on the different generations of enzymatic-based sensors, their recent advances, and provides an overview of the next generation of non-enzymatic sensors. Advancements in manufacturing techniques and materials are key in propelling the field of glucose sensing, however, significant limitations remain which are highlighted in this review and requires addressing to obtain a more stable, sensitive, selective, cost efficient, and real-time glucose sensor.


2016 ◽  
Vol 3 (4) ◽  
pp. 676-676 ◽  
Author(s):  
Xiaoling Zhong ◽  
Weiyong Yuan ◽  
Yuejun Kang ◽  
Jiale Xie ◽  
Fangxin Hu ◽  
...  

KIRYOKU ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 283-300
Author(s):  
Sri Sudarsih

The purpose of this study is to explore traditional moral values in Japanese society that are able to survive and be implemented in everyday life in the modern era. In addition, it is able to shape the distinctive character of the Japanese, including the role of women who contribute to maintaining traditional moral values. This research is a qualitative research field of philosophy with the object of formal values and the material object is the development of women's position in Japanese society. The results achieved in the study: Japanese women played an important role in the history of the struggle until Japan achieved prosperity and glory until now. This is based on the reason that Japanese women are able to maintain and preserve traditional moral values that still exist through early education in the family environment. These values can shape the character of children from an early age in the family. A family with character brings logical consequences to the life of a community with character so that it affects the culture as a whole.


2013 ◽  
Vol 9 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Tharrenos Bratitsis ◽  
Stavros Demetriadis

Computer Supported Collaborative Learning (CSCL) is concerned with how people learn when working and interacting in groups with the assistance of ICTs. The field involves collaboration, computer mediation, online – distance education which raises interesting theoretical considerations regarding the actual studying of learning within CSCL settings. Being a rather interdisciplinary research field in nature, it has a long history of controversy about its theory, methods, and definition. In this editorial, through a quick review of the literature the diversity of issues examined under the CSCL research field becomes obvious. Moreover, an attempt to categorize these research issues is made. In this vein, the four interesting contributions of this Special Issue, regarding theoretical perspectives and issues of research of the field, are introduced. They comply with the distinguished categories, but they open new research borders as well.


2014 ◽  
Vol 2 (3) ◽  
pp. 61 ◽  
Author(s):  
Pranab Jyoti Sarma

This paper carries out a critical review of the trends of historical writings in Assam. The historiographical study reveals that the beginning of the historical phase was, in fact, late in the North East region. Moreover, in many of these historical writings, the importance of the local histories of the communities of the region was ignored. The author highlights the fact that a pan-Indian history for the region may not be authentic enough to understand the cultural dynamics of the complex society of the Northeast. The author also focuses on corroborating ‘proper’ historical source material for reconstructing the history of the region rather than deriving inferences from mythology and legends. However, the importance of recent trends in historiography such as selective utilisation of oral traditions, folklores and memory studies has been emphasised. An alternative and more precise periodisation of the historical phase has been provided which does not, however, project any clear marker between periods and eras but emphasises on slow and steady transformations. Importance of archaeological sources and material evidence has been kept in mind while deriving periodical divisions. Relooking at the history of the Koches, Kacharis has been emphasised.


2010 ◽  
Vol 09 (03) ◽  
pp. C04 ◽  
Author(s):  
Toss Gascoigne ◽  
Donghong Cheng ◽  
Michel Claessens ◽  
Jennifer Metcalfe ◽  
Bernard Schiele ◽  
...  

The present comment examines to what extent science communication has attained the status of an academic discipline and a distinct research field, as opposed to the common view that science communication is merely a sub-discipline of media studies, sociology of science or history of science. Against this background, the authors of this comment chart the progress science communication has made as an emerging subject over the last 50 years in terms of a number of measures. Although discussions are still ongoing about the elements that must be present to constitute a legitimate disciplinary field, we show here that science communication meets four key elements that constitute an analytical framework to classify academic disciplines: the presence of a community; a history of inquiry; a mode of inquiry that defines how data is collected; and the existence of a communications network.


2013 ◽  
Vol 22 (2) ◽  
pp. 275-275

This discussion of Dagmar Herzog's Sexuality in Europe (2011) continues our new series of book fora. Herzog's new overview of changing European sexual mores and behaviour offers a jumping-off point for our panellists to discuss recent trends and future directions in the history of sexuality in twentieth-century Europe, East and West. Jeffrey Weeks (London South Bank University), Franz Eder (University of Vienna), Daniel Healey (University of Reading) and Victoria Harris (University of Birmingham) give their responses, and Herzog replies.


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