Bed-Based Ballistocardiography: Dataset and Ability to Track Cardiovascular Parameters

Background: The goal of this work was to create a sharable dataset of heart-driven signals, including ballistocardiograms (BCGs) and time-aligned electrocardiograms (ECGs), photoplethysmograms (PPGs), and blood pressure waveforms. Methods: A custom, bed-based ballistocardiographic system is described in detail. Affiliated cardiopulmonary signals are acquired using a GE Datex CardioCap 5 patient monitor (which collects ECG and PPG data) and a Finapres Medical Systems Finometer PRO (which provides continuous reconstructed brachial artery pressure waveforms and derived cardiovascular parameters). Results: Data were collected from 40 participants, 4 of whom had been or were currently diagnosed with a heart condition at the time they enrolled in the study. An investigation revealed that features extracted from a BCG could be used to track changes in systolic blood pressure (Pearson correlation coefficient of 0.54 +/− 0.15), dP/dtmax (Pearson correlation coefficient of 0.51 +/− 0.18), and stroke volume (Pearson correlation coefficient of 0.54 +/− 0.17). Conclusion: A collection of synchronized, heart-driven signals, including BCGs, ECGs, PPGs, and blood pressure waveforms, was acquired and made publicly available. An initial study indicated that bed-based ballistocardiography can be used to track beat-to-beat changes in systolic blood pressure and stroke volume. Significance: To the best of the authors’ knowledge, no other database that includes time-aligned ECG, PPG, BCG, and continuous blood pressure data is available to the public. This dataset could be used by other researchers for algorithm testing and development in this fast-growing field of health assessment, without requiring these individuals to invest considerable time and resources into hardware development and data collection.

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Use of Multiple Visits to Increase Blood Pressure Tracking Correlations in Childhood

PEDIATRICS ◽

10.1542/peds.87.5.708 ◽

1991 ◽

Vol 87 (5) ◽

pp. 708-711

Author(s):

Matthew W. Gillman ◽

Bernard Rosner ◽

Denis A. Evans ◽

Laurel A. Smith ◽

James O. Taylor ◽

...

Keyword(s):

Blood Pressure ◽

Diastolic Blood Pressure ◽

Correlation Coefficient ◽

Diastolic Pressure ◽

Pearson Correlation ◽

Systolic Pressure ◽

Pearson Correlation Coefficient ◽

Increase Blood Pressure ◽

Multiple Visit

Previous studies of childhood blood pressure have shown tracking correlations, which estimate the magnitude of association between initial and subsequent measurements, to be lower than corresponding adult values. Inasmuch as this disparity could arise from failing to account for a larger week-to-week variability in children, blood pressure was measured for 4 successive years, on four weekly visits in each year, and with three measurements at each visit, using a random-zero sphygmomanometer, in a cohort of 333 schoolchildren aged 8 through 15 at entry. Ninety percent of subjects had measurements in 1 or more years of follow-up. For all follow-up periods (1, 2, and 3 years from baseline), the Pearson correlation coefficient (r) for both systolic and diastolic blood pressure rose substantially with the number of weekly visits used to calculate each subject's yearly blood pressure (P < .0001). For systolic pressure, the 3-year r values for 1, 2, 3, and 4 visits were .45, .55, .64, and .69, respectively. For diastolic pressure (Korotkoff phase 4), the corresponding values were .28, .41, .47, and .54. These higher multiple-visit estimates of tracking approximate published adult values and raise the possibility that prediction of adult blood pressure from childhood measurements may be improved by averaging readings from multiple weekly visits.

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SAT-LB126 Metformin Attenuates Sodium Retention and Blood Pressure in Hypertensive Diabetic Mice by Reducing the Phosphorylation of Renal NCC and Its Association With the Actin Cytoskeleton

Journal of the Endocrine Society ◽

10.1210/jendso/bvaa046.2201 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

Author(s):

Mohammed F Gholam ◽

Alina Waleed ◽

Kubra M Tuna ◽

Morgan Carson-Marino ◽

Kevin M Chacko ◽

...

Keyword(s):

Blood Pressure ◽

Actin Cytoskeleton ◽

Correlation Coefficient ◽

Western Blotting ◽

Pearson Correlation ◽

Left Kidney ◽

Control Group ◽

Pearson Correlation Coefficient ◽

Sodium Retention ◽

Oral Gavage

Abstract Metformin is the first-line drug in the treatment of type 2 diabetes mellitus. The aim of this work was to evaluate the efficacy of metformin treatment in reducing blood pressure and investigate the molecular mechanism using a preclinical animal model. Adult male and female diabetic db/db mice with a blood glucose of greater than 300 mg/dl were salt-loaded (8% NaCl) for 10 days to induce hypertension. The mice were subject to metabolic cage studies for 24 hour urine collections in order to measure urinary electrolytes, albumin, and creatinine. Blood pressure was measured weekly by the tail-cuff method to assess the effect of metformin or vehicle given by oral gavage (dose of 60 mg/kg of body weight per day). At the end of the study the mice was euthanized and the left kidney was formalin-fixed and paraffin-embedded for immunohistochemistry while the right kidney was homogenized for Western blotting. Western blotting showed attenuation of total NCC and phospho-NCC in diabetic db/db mice given an oral gavage of metformin (Pearson correlation coefficient: 0.9470 +/- 2.52e-3) compared to vehicle (Pearson correlation coefficient: 0.9800 +/- 2.86e-3). Immunohistochemical analysis showed less co-localization of the actin cytoskeleton protein filamin and phosphorylated NCC in the metformin treated group compared to the control group. Taken together, we show metformin decreases sodium retention and blood pressure by reducing the density of renal NCC at the luminal membrane and the association between NCC and the actin cytoskeleton.

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Prevalence of Anesthesia Complications in Orthopedic Surgeries and its Related Factors

Journal of Client-centered Nursing Care ◽

10.32598/jccnc.7.2.295.3 ◽

2021 ◽

Vol 7 (2) ◽

pp. 123-130

Author(s):

Hossein Kiani ◽

◽

Masoumeh Hoseinian ◽

Zohreh Sadat ◽

Neda Mirbagher Ajorpaz ◽

...

Keyword(s):

Blood Pressure ◽

General Anesthesia ◽

Correlation Coefficient ◽

Significant Relationship ◽

Elective Surgery ◽

Pearson Correlation ◽

Pearson Correlation Coefficient ◽

Related Factors ◽

Duration Of Surgery ◽

Anesthesia Complications

Background: The duration of surgery in orthopedic surgeries is often longer than one hour. Therefore, these patients are at further risk of complications induced by general anesthesia. The present study aimed to determine the prevalence of anesthesia complications in orthopedic surgeries and its related factors. Methods: This cross-sectional study was performed on 400 patients undergoing orthopedic surgery in Shahid Beheshti Hospital of Kashan Province, Iran, in 2020. The study subjects were recruited by convenience sampling method. We included those who similarly underwent general anesthesia for elective surgery and were transferred to Post-Anesthesia Care Unit (PACU). The research instruments included a demographic questionnaire and a checklist for recording complications (shivering, pain, nausea, vomiting, & vital signs). The necessary data were recorded after the patient was admitted to the PACU, as well as half an hour and one hour later. The obtained data were analyzed using the Chi-squared test, Independent Samples t-test, one-way Analysis of Variance (ANOVA), Pearson correlation coefficient, and logistic regression analysis in SPSS v. 16. Results: The present research results suggested that the most and least frequent complications were vomiting (91.8%) and changes in blood pressure (5%), respectively. Gender was significantly associated with pain, nausea, and hypertension (P<0.05). The Pearson correlation coefficient data indicated a significant relationship between the duration of anesthesia and the mean scores of shivering, pain, nausea, tachycardia, and tachypnea (P<0.05). There was also a significant relationship between the types of surgery and shivering, pain, blood pressure, and nausea (P<0.05). Pulse rate was significantly associated with complete intravenous anesthesia and the duration of anesthesia (P<0.05). Conclusion: The relatively high incidence of post-anesthesia complications in orthopedic surgeries indicates the significance of employing skilled personnel as well as using adequate monitoring equipment at the PACU. Such measures help to decrease mortality and morbidity among patients, also save on hospital costs.

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On the Psychological Reality of the Pearson Correlation Coefficient: Effects of Objective Covariation on Subjective Estimates

PsycEXTRA Dataset ◽

10.1037/e537052012-416 ◽

2004 ◽

Author(s):

Richard B. Anderson ◽

Andrea M. Angott ◽

Michael E. Doherty

Keyword(s):

Correlation Coefficient ◽

Pearson Correlation ◽

Pearson Correlation Coefficient ◽

Psychological Reality ◽

Subjective Estimates

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Relationship between Invasive and Non-Invasive Hemodynamic Measures in Experimental Pulmonary Hypertension

Current Respiratory Medicine Reviews ◽

10.2174/1573398x16666200516180118 ◽

2020 ◽

Vol 16 (1) ◽

pp. 47-53

Author(s):

Vicente Benavides-Córdoba ◽

Mauricio Palacios Gómez

Keyword(s):

Heart Rate ◽

Pulmonary Hypertension ◽

Ejection Fraction ◽

Right Ventricle ◽

Correlation Coefficient ◽

Pearson Correlation ◽

Systolic Pressure ◽

Control Group ◽

Pearson Correlation Coefficient ◽

Non Invasive

Introduction: Animal models have been used to understand the pathophysiology of pulmonary hypertension, to describe the mechanisms of action and to evaluate promising active ingredients. The monocrotaline-induced pulmonary hypertension model is the most used animal model. In this model, invasive and non-invasive hemodynamic variables that resemble human measurements have been used. Aim: To define if non-invasive variables can predict hemodynamic measures in the monocrotaline-induced pulmonary hypertension model. Materials and Methods: Twenty 6-week old male Wistar rats weighing between 250-300g from the bioterium of the Universidad del Valle (Cali - Colombia) were used in order to establish that the relationships between invasive and non-invasive variables are sustained in different conditions (healthy, hypertrophy and treated). The animals were organized into three groups, a control group who was given 0.9% saline solution subcutaneously (sc), a group with pulmonary hypertension induced with a single subcutaneous dose of Monocrotaline 30 mg/kg, and a group with pulmonary hypertension with 30 mg/kg of monocrotaline treated with Sildenafil. Right ventricle ejection fraction, heart rate, right ventricle systolic pressure and the extent of hypertrophy were measured. The functional relation between any two variables was evaluated by the Pearson correlation coefficient. Results: It was found that all correlations were statistically significant (p <0.01). The strongest correlation was the inverse one between the RVEF and the Fulton index (r = -0.82). The Fulton index also had a strong correlation with the RVSP (r = 0.79). The Pearson correlation coefficient between the RVEF and the RVSP was -0.81, meaning that the higher the systolic pressure in the right ventricle, the lower the ejection fraction value. Heart rate was significantly correlated to the other three variables studied, although with relatively low correlation. Conclusion: The correlations obtained in this study indicate that the parameters evaluated in the research related to experimental pulmonary hypertension correlate adequately and that the measurements that are currently made are adequate and consistent with each other, that is, they have good predictive capacity.

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Bioinformatics Study on Serum Triglyceride Levels for Analysis of a Potential Risk Factor Affecting Blood Pressure Variability

Current Bioinformatics ◽

10.2174/1574893614666190109152809 ◽

2019 ◽

Vol 14 (5) ◽

pp. 376-385 ◽

Cited By ~ 2

Author(s):

Lin Xu ◽

Jiangming Huang ◽

Zhe Zhang ◽

Jian Qiu ◽

Yan Guo ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Blood Pressure Variability ◽

Partial Correlation ◽

Pearson Correlation ◽

Target Organ Damage ◽

Serum Triglyceride ◽

Hypertensive Patients ◽

Group A ◽

Group B

Objective: The purpose of this study was to establish whether Triglycerides (TGs) are related to Blood Pressure (BP) variability and whether controlling TG levels leads to better BP variability management and prevents Cardiovascular Disease (CVD). Methods: In this study, we enrolled 106 hypertensive patients and 80 non-hypertensive patients. Pearson correlation and partial correlation analyses were used to define the relationships between TG levels and BP variability in all subjects. Patients with hypertension were divided into two subgroups according to TG level: Group A (TG<1.7 mmol/L) and Group B (TG>=1.7 mmol/L). The heterogeneity between the two subgroups was compared using t tests and covariance analysis. Results: TG levels and BP variability were significantly different between the hypertensive and non-hypertensive patients. Two-tailed Pearson correlation tests showed that TG levels are positively associated with many BP variability measures in all subjects. After reducing other confounding factors, the partial correlation analysis revealed that TG levels are still related to the Standard Deviation (SD), Coefficient of Variation (CV) of nighttime systolic blood pressure and CV of nighttime diastolic blood pressure, respectively (each p<0.05). In the subgroups, group A had a lower SD of nighttime Systolic Blood Pressure (SBP_night_SD; 11.39±3.80 and 13.39±4.16, p=0.011), CV of nighttime systolic blood pressure (SBP_night_CV; 0.09±0.03 and 0.11±0.03, p=0.014) and average real variability of nighttime systolic blood pressure (SBP_night_ARV; 10.99±3.98 and 12.6±3.95, p=0.024) compared with group B, even after adjusting for age and other lipid indicators. Conclusion: TG levels are significantly associated with BP variability and hypertriglyceridemia, which affects blood pressure variability before causing target organ damage.

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Assessment of the Dissimilarities of EDI and SPI Measures for Drought Determination in South Africa

Water ◽

10.3390/w13010082 ◽

2021 ◽

Vol 13 (1) ◽

pp. 82

Author(s):

Omolola M. Adisa ◽

Muthoni Masinde ◽

Joel O. Botai

Keyword(s):

South Africa ◽

South African ◽

Correlation Coefficient ◽

Pearson Correlation ◽

Standardized Precipitation Index ◽

Drought Monitoring ◽

Drought Indices ◽

Drought Severity ◽

Pearson Correlation Coefficient ◽

Drought Duration

This study examines the (dis)similarity of two commonly used indices Standardized Precipitation Index (SPI) computed over accumulation periods 1-month, 3-month, 6-month, and 12-month (hereafter SPI-1, SPI-3, SPI-6, and SPI-12, respectively) and Effective Drought Index (EDI). The analysis is based on two drought monitoring indicators (derived from SPI and EDI), namely, the Drought Duration (DD) and Drought Severity (DS) across the 93 South African Weather Service’s delineated rainfall districts over South Africa from 1980 to 2019. In the study, the Pearson correlation coefficient dissimilarity and periodogram dissimilarity estimates were used. The results indicate a positive correlation for the Pearson correlation coefficient dissimilarity and a positive value for periodogram of dissimilarity in both the DD and DS. With the Pearson correlation coefficient dissimilarity, the study demonstrates that the values of the SPI-1/EDI pair and the SPI-3/EDI pair exhibit the highest similar values for DD, while the SPI-6/EDI pair shows the highest similar values for DS. Moreover, dissimilarities are more obvious in SPI-12/EDI pair for DD and DS. When a periodogram of dissimilarity is used, the values of the SPI-1/EDI pair and SPI-6/EDI pair exhibit the highest similar values for DD, while SPI-1/EDI displayed the highest similar values for DS. Overall, the two measures show that the highest similarity is obtained in the SPI-1/EDI pair for DS. The results obtainable in this study contribute towards an in-depth knowledge of deviation between the EDI and SPI values for South Africa, depicting that these two drought indices values are replaceable in some rainfall districts of South Africa for drought monitoring and prediction, and this is a step towards the selection of the appropriate drought indices.

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