scholarly journals Plant-Derived Saponins: A Review of Their Surfactant Properties and Applications

Sci ◽  
2021 ◽  
Vol 3 (4) ◽  
pp. 44
Author(s):  
Summi Rai ◽  
Eliza Acharya-Siwakoti ◽  
Ananda Kafle ◽  
Hari Prasad Devkota ◽  
Ajaya Bhattarai
Keyword(s):  
Biological Activities ◽  
Antidiabetic Activity ◽  
Environmental Concerns ◽  
Plant Metabolites ◽  
Surfactant Properties ◽  
The Past ◽  
Natural Surfactant ◽  
Surface Active Properties ◽  
Surface Active ◽  
Synthetic Surfactants

In response to increasing natural surfactant demand and environmental concerns, natural plant-based surfactants have been replacing synthetic ones. Saponins belong to a class of plant metabolites with surfactant properties that are widely distributed in nature. They are eco-friendly because of their natural origin and biodegradable. To date, many plant-based saponins have been investigated for their surface activity. An overview of saponins with a particular focus on their surface-active properties is presented in this article. For this purpose, works published in the past few decades, which report better surfactant relevant properties of saponins than synthetic ones, were extensively studied. The investigations on the potential surfactant application of saponins are also documented. Moreover, some biological activities of saponins such as antimicrobial activity, antidiabetic activity, adjuvant potentials, anticancer activity, and others are reported. Plants rich in saponins are widely distributed in nature, offering great potential for the replacement of toxic synthetic surfactants in a variety of modern commercial products and these saponins exhibit excellent surface and biological activities. New opportunities and challenges associated with the development of saponin-based commercial formulations in the future are also discussed in detail.

Plant-derived surfactants as an alternative to synthetic surfactants: surface and antioxidant activities

2016 ◽  
Vol 70 (2) ◽  
Author(s):  
Lenka Tmáková ◽  
Stanislav Sekretár ◽  
Štefan Schmidt
Keyword(s):  
Antioxidant Activity ◽  
Antioxidant Activities ◽  
Surface Active Properties ◽  
Surface Active ◽  
Synthetic Surfactants

Biosurfactants have great advantages as an eco-friendly alternative to synthetic surfactants. Surface active properties and antioxidant activity of extracts prepared from

scholarly journals Asphaltenes at Oil/Gas Interfaces: Foamability Even with No Significant Surface Activity

2018 ◽  
Vol 3 (1) ◽  
pp. 2
Author(s):  
Mélanie Arangalage ◽  
Jean-Philippe Gingras ◽  
Nicolas Passade-Boupat ◽  
François Lequeux ◽  
Laurence Talini
Keyword(s):  
Marangoni Effect ◽  
Oil Industry ◽  
Model Systems ◽  
Crude Oils ◽  
Gas Stations ◽  
The Past ◽  
Surface Active Properties ◽  
Oil Mixtures ◽  
Surface Active ◽  
Oil Gas

In the oil industry, oil foams can be found at different steps from the crude oil treatment to the gas stations. Their lifetime can sometimes reach several hours and be much longer than the residence times available for gas/liquid separation. However, the conditions of formation and stability of such foams have been poorly studied in the literature, in contrast to the foamability of aqueous systems. On the fields, it is currently observed that crude oils enriched with asphaltenes form particularly stable foams. In this work, we have studied the influence of asphaltenes on the foamability of oil mixtures. All the experiments were performed on model systems of crude oils, that-is-to-say decane/toluene mixtures containing asphaltenes at concentrations ranging from 0.01 to 5 wt%. We in particular demonstrate that, within the investigated concentration range, asphaltenes from two different wells do not have any significant surface active properties despite their contribution to the foamability of oil mixtures. We show that the formation of an asphaltene layer at the interface with air that has been evidenced in the past results from solvent evaporation. Using a recently developed experiment based on the Marangoni effect with our model oils, we demonstrate that asphaltenes are not surface active in those oils. We further characterize the oil foamability by measuring the lifetime of the foam formed by blowing nitrogen through the liquid in a column. At concentrations larger than 1 wt%, asphaltenes significantly enhance the foamability of the oil mixtures. Moreover, the closer the asphaltenes are to their limit of precipitation the larger the foamability. However, we evidence that the oil mixtures themselves foam and we show the importance to consider that effect on the foamability. In addition, we observe that the foamability of the asphaltenes solutions unexpectedly varies with the initial height of the liquid in the column. We suggest that, although not significantly modifying the surface tension, the asphaltenes could be trapped at the oil/gas interface and thus prevent bubble coalescence.

scholarly journals Exogenous Pulmonary Surfactant as a Vehicle for Antimicrobials: Assessment of Surfactant-Antibacterial InteractionsIn Vitro

Scientifica ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Alexei Birkun
Keyword(s):  
Pulmonary Surfactant ◽  
Mutual Influence ◽  
Exogenous Surfactant ◽  
Natural Surfactant ◽  
Subsequent Investigation ◽  
Surface Active Properties ◽  
Colistimethate Sodium ◽  
Surface Active

Owing to its unique surface-active properties, an exogenous pulmonary surfactant may become a promising drug delivery agent, in particular, acting as a vehicle for antibiotics in topical treatment of pneumonia. The purpose of this study was to assess a mutual influence of natural surfactant preparation and three antibiotics (amikacin, cefepime, and colistimethate sodium)in vitroand to identify appropriate combination(s) for subsequentin vivoinvestigations of experimental surfactant/antibiotic mixtures. Influence of antibiotics on surface-active properties of exogenous surfactant was assessed using the modified Pattle method. Effects of exogenous surfactant on antibacterial activity of antimicrobials againstStaphylococcus aureus,Klebsiella pneumoniae, andPseudomonas aeruginosawere evaluated using conventional microbiologic procedures. Addition of amikacin or cefepime to surfactant had no significant influence on surface-active properties of the latter. Obvious reduction of surface-active properties was confirmed for surfactant/colistimethate composition. When suspended with antibiotics, surfactant either had no impact on their antimicrobial activity (amikacin) or exerted mild to moderate influence (reduction of cefepime bactericidal activity and increase of colistimethate bacteriostatic activity againstS. aureusandP. aeruginosa). Considering favorable compatibility profile, the surfactant/amikacin combination is advisable for subsequent investigation of joint surfactant/antibacterial therapy in animals with bacterial pneumonia.

Surface Active Properties and Biological Activities of Novel Anionic Surfactant Based on Oxapyridazinone Derivatives

2015 ◽  
Vol 19 (1) ◽  
pp. 137-144 ◽  
Author(s):  
Manal Mohamed El-Shahawi ◽  
Alyaa Abou Sheashaa Shalaby ◽  
Adel Mohy El-Din Gabre ◽  
Abd El-Hamed Mahmoud Ghonim
Keyword(s):  
Anionic Surfactant ◽  
Biological Activities ◽  
Surface Active Properties ◽  
Surface Active

scholarly journals Plant-Derived Saponins: A Review of Their Surfactant Properties and Applications

2021 ◽  
Author(s):  
Summi Rai ◽  
Eliza Acharya ◽  
Ananda Kafle ◽  
Hari Prasad Devkota ◽  
Ajaya Bhattarai
Keyword(s):  
Environmental Concern ◽  
Biological Activities ◽  
Wide Distribution ◽  
Complete Replacement ◽  
Surface Active Properties ◽  
Anti Cancer ◽  
Natural Surfactants ◽  
Foam Forming ◽  
Global Agenda ◽  
Synthetic Surfactants

Increasing environmental concern and consumer demand for natural, sustainable and eco-friendly products have prompted the replacement of synthetic surfactants with their natural plant-based alternatives. Saponins are the plant based natural surfactants characterized by their foam forming properties in aqueous solution. Their natural origin makes them eco-friendly, bio-degradable and non-toxic. Further, they possess better physicochemical properties than the syn-thetic ones. They are also reported to exhibit a lot of useful biological activities such as anti-cancer, antifungal, anti-inflammatory, antimicrobial, antioxidant and cholesterol-lowering properties. Because of their excellent surface activity, biological activities and wide distribution in nature, saponin rich plants deserve deeper insight as a sustainable source of natural surfactants as they possess the potential to replace toxic synthetic surfactants abundant today. This review article is intended to provide a brief overview on the saponins with a special notion on their surface-active properties. It encourages further studies on development of commercial formulations based on saponins for the complete replacement of the synthetic counter parts, making better use of plants sources thereby contributing to global agenda of green environment.

scholarly journals Impact of the number of rhamnose moieties of rhamnolipids on the structure, lateral organization and morphology of model biomembranes

Soft Matter ◽  
2021 ◽  
Author(s):  
Marius Herzog ◽  
Lei Li ◽  
Christian C. Blesken ◽  
Gina Welsing ◽  
Till Tiso ◽  
...  
Keyword(s):  
Biological Activities ◽  
Industrial Applications ◽  
Surface Active Properties ◽  
Wide Range ◽  
Surface Active ◽  
Lateral Organization

Various studies have described remarkable biological activities and surface-active properties of rhamnolipids, leading to their proposed use in a wide range of industrial applications.

Click Reactions in Chemistry of Triterpenes - Advances Towards Development of Potential Therapeutics

2018 ◽  
Vol 25 (5) ◽  
pp. 636-658 ◽  
Author(s):  
Jan Pokorny ◽  
Lucie Borkova ◽  
Milan Urban
Keyword(s):  
Biological Activities ◽  
Synthetic Approach ◽  
Clinical Use ◽  
New Approach ◽  
Click Reactions ◽  
Drug Candidates ◽  
The Past ◽  
Low Toxicity ◽  
New Compounds ◽  
Potential Therapeutics

Triterpenoids are natural compounds with a large variety of biological activities such as anticancer, antiviral, antibacterial, antifungal, antiparazitic, antiinflammatory and others. Despite their low toxicity and simple availability from the natural resources, their clinical use is still severely limited by their higher IC50 and worse pharmacological properties than in the currently used therapeutics. This fact encouraged a number of researchers to develop new terpenic derivatives more suitable for the potential clinical use. This review summarizes a new approach to improve both, the activity and ADME-Tox properties by connecting active terpenes to another modifying molecules using click reactions. Within the past few years, this synthetic approach was well explored yielding a lot of great improvements of the parent compounds along with some less successful attempts. A large quantity of the new compounds presented here are superior in both activity and ADME-Tox properties to their parents. This review should serve the researchers who need to promote their hit triterpenic structures towards their clinical use and it is intended as a guide for the chemical synthesis of better drug candidates.

Structural and Bioactive Studies of Halogenated Constituents from Sponges

2020 ◽  
Vol 27 (14) ◽  
pp. 2335-2360 ◽  
Author(s):  
Chao Li ◽  
Dayong Shi
Keyword(s):  
Microbial Communities ◽  
Organic Compounds ◽  
Biological Activities ◽  
Marine Sponges ◽  
Nitrogen Compounds ◽  
Halogenated Organic Compounds ◽  
Bioactive Natural Products ◽  
The Past ◽  
Tyrosine Derivatives ◽  
Polyunsaturated Lipids

: Marine organisms are abundant sources of bioactive natural products. Among metabolites produced by sponges and their associated microbial communities, halogenated natural compounds accounted for an important part due to their potent biological activities. The present review updates and compiles a total of 258 halogenated organic compounds isolated in the past three decades, especially brominated derivatives derived from 31 genera of marine sponges. These compounds can be classified as the following classes: brominated polyunsaturated lipids, nitrogen compounds, brominated tyrosine derivatives and other halogenated compounds. These substances were listed together with their source organisms, structures and bioactivities. For this purpose, 84 references were consulted.

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