scholarly journals Pancreatic Injury after COVID-19 Vaccine—A Case Report

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 576
Author(s):  
Artur Cieślewicz ◽  
Magdalena Dudek ◽  
Iwona Krela-Kaźmierczak ◽  
Anna Jabłecka ◽  
Maciej Lesiak ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Adverse Effects ◽  
Medicinal Product ◽  
Pancreatic Injury ◽  
Genetically Engineered ◽  
Close Monitoring ◽  
Safety And Efficacy

The COVID-19 pandemic has caused more than 3 million deaths worldwide. Recently developed genetically engineered vaccines are the most critical solution for controlling the pandemic. Clinical trials on a large number of participants confirmed their safety and efficacy. However, with the growing number of vaccinated people, new infrequent adverse effects have been reported, not described in the medicinal product characteristics. We would like to report a case of acute pancreatic injury that occurred shortly after administering Pfizer BioNTech COVID-19 mRNA vaccine (Comirnaty). The report points out the potential need for close monitoring of patients reporting abdominal pain after vaccination (unresponsive to standard oral painkillers) because such symptom can be associated with acute pancreatitis.

scholarly journals ATORVASTATIN INDUCED ACUTE PANCREATITIS? - A RARE CASE REPORT

2019 ◽  
pp. 1-2
Author(s):  
JAIDEV KUMAR ◽  
ASHOKA ◽  
RAKSHITH ◽  
UMESH
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Health Care Professionals ◽  
Time Interval ◽  
Close Monitoring ◽  
Drug Induced ◽  
Converting Enzyme Inhibitors ◽  
Short Period ◽  
Objective Evidence

Acute pancreatitis is a clinical condition characterized by inflammation of pancreas. The specific time interval to suspect any patient as acute pancreatitis is not clearly defined in any therapeutic guideline and usually symptoms will be lasted for a short period of time. The management of acute pancreatitis always depends on underlying cause. The common medications that can cause acute pancreatitis include angiotensin-converting enzyme inhibitors, azathioprine, and pentamidine. According to the patient case history, abdominal pain was on and off; the patient also received nonsteroidal anti-inflammatory drugs, i.e., tablet aceclofenac 100 mg for abdominal pain, whenever he was experiencing pain and it got subsided only for short period. This case report did not have clear subjective and objective evidence to suspect atorvastatin which was the main culprit of causing acute pancreatitis. The incidence of causing drug-induced acute pancreatitis is very low which was accountable for only 0.1–2%. This case report concludes that all health-care professionals need to have close monitoring of atorvastatin causing acute pancreatitis which is very rarely seen.

scholarly journals SARS-CoV-2 Infection as a Cause of Acute Pancreatitis in a Child—A Case Report

2021 ◽  
Vol 13 (4) ◽  
pp. 552-557
Author(s):  
Natalia Kopiczko ◽  
Kamila Kwiatek-Średzińska ◽  
Mirosława Uścinowicz ◽  
Monika Kowalczuk-Krystoń ◽  
Dariusz Marek Lebensztejn
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
The Novel ◽  
Gastrointestinal Manifestations ◽  
Number Of Patients ◽  
Growing Body ◽  
Novel Coronavirus ◽  
Mild Acute Pancreatitis ◽  
First Time

The novel coronavirus disease (COVID-19) was detected for the first time in China in December 2019. Soon after it was declared a pandemic. Main symptoms include fever, dyspnea, cough, muscle pain, headache, anosmia and ageusia, however a growing body of evidence shows that other organs can be affected. Gastrointestinal manifestations have been observed in a considerable number of patients and include abdominal pain, diarrhea and vomiting. The involvement of liver as well as pancreas has been also described, however there are only a few cases of acute pancreatitis reported in patients with COVID-19. Therefore, we present a case of 6-year-old child with mild acute pancreatitis and COVID-19 pneumonia.

scholarly journals Case Report: Acute Abdominal Pain as Presentation of Pneumonia and Acute Pancreatitis in a Pediatric Patient With COVID-19

JPGN Reports ◽  
2020 ◽  
Vol 2 (1) ◽  
pp. e011
Author(s):  
Raul E. Sanchez ◽  
Colleen B. Flahive ◽  
Ethan A. Mezoff ◽  
Cheryl Gariepy ◽  
W. Garrett Hunt ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Pediatric Patient ◽  
Acute Abdominal Pain

scholarly journals Insights into Acute Pancreatitis Associated COVID-19: Literature Review

2021 ◽  
Vol 10 (24) ◽  
pp. 5902
Author(s):  
Yasameen E. Muzahim ◽  
David C. Parish ◽  
Hemant Goyal
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Respiratory Symptoms ◽  
Clinical Symptoms ◽  
Pancreatic Injury ◽  
Insufficient Data ◽  
Converting Enzyme ◽  
Serum Lipase ◽  
Asymptomatic Patients ◽  
Organ Systems

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) primarily affects the lungs, causing respiratory symptoms. However, the infection clearly affects all organ systems including the gastrointestinal system. Acute pancreatitis associated with coronavirus disease 2019 (COVID-19) has been widely reported Recent studies have discussed pancreatic compromise incidentally in asymptomatic patients, or in a form of clinical symptoms such as abdominal pain, nausea, or vomiting, which is further reflected in some cases with abnormal serum lipase and amylase levels It was suggested that upregulation of angiotensin-converting enzyme II cell receptors or inflammatory cytokines play a major role in predisposing pancreatic injury in SARS-CoV-2 positive patients To date, there is insufficient data to establish the causality of acute pancreatitis in SARS-CoV-2 infected cases. In this paper, we organize recent studies conducted to observe the frequency of acute pancreatitis associated with COVID-19 cases while highlighting present hypotheses, predisposing factors, and their effect on the outcome, and point to gaps in our knowledge.

Doxycycline-Induced Gastric Perforation

2021 ◽  
pp. 000313482110474
Author(s):  
Yeahwa Hong ◽  
Christopher Staniorski ◽  
Dean Pollack ◽  
Steven Evans
Keyword(s):  
Abdominal Pain ◽  
Case Report ◽  
Chest Pain ◽  
Adverse Effects ◽  
Diagnostic Criteria ◽  
Gastric Perforation ◽  
Mucosal Injury ◽  
First Case ◽  
Life Threatening

Esophageal and gastric mucosal injuries are well-documented adverse effects of doxycycline leading to odynophagia, chest pain, and abdominal pain. There are no clear diagnostic criteria for such adverse effects; hence, the diagnosis depends heavily on thorough history. There is a paucity of literature describing life-threatening complications from doxycycline-induced mucosal injury, such as hemorrhage and perforation. We present the first case report describing a gastric perforation from doxycycline use.

scholarly journals A Rare Case Report of Pseudo Pancreatic Cyst in a Child

2021 ◽  
Vol 10 (31) ◽  
pp. 2535-2537
Author(s):  
Syed Athhar Saqqaf ◽  
Amar Taksande ◽  
Revat Meshram
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
World Literature ◽  
Pancreatic Pseudocyst ◽  
Fibrous Tissue ◽  
Previous History ◽  
Pancreatic Cysts ◽  
Serum Lipase ◽  
History Of

It is difficult to diagnose pancreatic cysts in children. Any previous history of acute pancreatitis is very important because it can lead to a wide set of complications like pseudocyst, pancreatic necrosis, splenic venous thrombosis etc. The most known and common cause of pancreatic pseudocyst in children is trauma. The characteristic features of pancreatitis include abdominal pain, serum lipase or amylase values three times more than that of the normal range and characteristic radiological features. Pancreatic pseudocyst may occur in 15 % of children with acute pancreatitis as a complication.1 Pancreatic juice collection enclosed by a wall of granulation or fibrous tissue, is defined as a pseudocyst. As the resulting cyst has no true endothelial lining, it is classified as a pseudocyst.2 The pseudocyst contains inflammatory pancreatic fluid, mainly the lipase enzyme or semisolid matter. The incidence of pseudocyst is relatively low 1.6 % - 4.5 %, or 0.5 - 1 per 100 000 adults per year.2 Very few cases of pancreatic pseudocyst have been reported in world literature. Commonly, it develops as a sequel of acute or chronic pancreatitis. It develops around 4 weeks after the episode of acute pancreatitis.3 It is characterized by pancreatic inflammation, abdominal pain and raised levels of serum digestive enzymes.4 Here we discuss a case report of pancreatic pseudocyst in a 10-year-old male child presenting with history of abdominal pain and decreased appetite.

scholarly journals A serendipitous case report of acute pancreatitis complicated by pseudocyst in a patient with COVID-19

2021 ◽  
Author(s):  
Vallish Shenoy ◽  
Aditya J. J Baindur
Keyword(s):  
Acute Pancreatitis ◽  
Case Report ◽  
Gastrointestinal Tract ◽  
Severe Acute Respiratory Syndrome ◽  
Rare Case ◽  
Gastrointestinal Disease ◽  
Pancreatic Injury ◽  
Etiologic Agent ◽  
Exocrine Glands ◽  
Acute Hospitalization

Acute pancreatitis is a common gastrointestinal disease, most frequently requiring acute hospitalization. During SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) pandemic, the etiologic agent of COVID-19, several studies described the involvement of other tissues besides the respiratory tract, such as the gastrointestinal tract. In pancreas, ACE-2 receptor is expressed in exocrine glands and islets, both being targets for the virus and subsequent pancreatic injury. There are few articles which report pancreatic injury in COVID-19 patients but most of them do not report acute pancreatitis. Diagnosing acute pancreatitis in the setting of COVID-19 pandemic is challenging and requires ruling out all other potential causes of pancreatitis. Herein we report a rare case of severe acute pancreatitis.

scholarly journals Acute pancreatitis associated with acute viral hepatitis: case report and review of literature

2009 ◽  
Vol 51 (6) ◽  
pp. 349-351 ◽  
Author(s):  
Danilo Bora Moleta ◽  
Fábio Toshio Kakitani ◽  
Adma Silva de Lima ◽  
João César Beenke França ◽  
Sonia Mara Raboni
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Acute Hepatitis ◽  
Viral Hepatitis ◽  
Acute Viral Hepatitis ◽  
Hepatitis Virus ◽  
Common Disease ◽  
Review Of Literature ◽  
Hepatitis Case

This case report, along with the review presented, describes a patient diagnosed with acute viral hepatitis, who developed a framework of intense abdominal pain and laboratorial alterations compatible with acute pancreatitis. The association of acute pancreatitis complicating fulminant and non-fulminant acute hepatitis virus (AHV) has been reported and several mechanisms have been proposed for this complication, but so far none is clearly involved. As acute hepatitis is a common disease, it is important to stimulate the development of other studies in order to determine local incidence and profile of patients presenting this association in our environment.

scholarly journals Acute pancreatitis in a COVID-19 patient in Brazil: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Caroline Petersen da Costa Ferreira ◽  
Kalynne Rodrigues Marques ◽  
Gustavo Henrique Ferreira de Mattos ◽  
Tércio de Campos
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Epigastric Pain ◽  
White Male ◽  
Empiric Antibiotic Therapy ◽  
Pancreatic Involvement ◽  
Number Of Patients ◽  
Empiric Antibiotic

Abstract Background The consequences of the coronavirus disease 2019 pandemic have already exceeded 10 million infected and more than 560,000 deaths worldwide since its inception. Currently, it is known that the disease affects mainly the respiratory system; however, recent studies have shown an increase in the number of patients with manifestations in other systems, including gastrointestinal manifestations. There is a lack of literature regarding the development of acute pancreatitis as a complication of coronavirus disease 2019. Case report We report a case of acute pancreatitis in a white male patient with coronavirus disease 2019. A 35-year-old man (body mass index 31.5) had acute epigastric pain radiating to his back, dyspnea, nausea, and vomiting for 2 days. The patient was diagnosed with severe acute pancreatitis (AP)-APACHE II: 5, SOFA: 3, Marshall: 0; then he was transferred from ED to the semi-intensive care unit. He tested positive for severe acute respiratory syndrome coronavirus 2 on reverse transcription-polymerase chain reaction, and his chest computed tomography findings were compatible with coronavirus disease 2019. Treatment was based on bowel rest, fluid resuscitation, analgesia, and empiric antibiotic therapy. At day 12, with resolution of abdominal pain and improvement of the respiratory condition, the patient was discharged. Conclusion Since there is still limited evidence of pancreatic involvement in severe acute respiratory syndrome coronavirus 2 infection, no definite conclusion can be made. Given the lack of other etiology, we consider the possibility that the patient’s acute pancreatitis could be secondary to coronavirus disease 2019 infection, and we suggest investigation of pancreas-specific plasma amylase in patients with coronavirus disease 2019 and abdominal pain.

scholarly journals Clinical and imaging findings of walled-off pancreatic necrosis misdiagnosed as an intra-abdominal neoplasia in a Schnauzer dog: A case report

2021 ◽  
Vol 66 (No. 1) ◽  
pp. 32-39
Author(s):  
J Kim ◽  
J Ko ◽  
H Yoon ◽  
H Kim ◽  
J Hwang ◽  
...  
Keyword(s):  
Acute Pancreatitis ◽  
Abdominal Pain ◽  
Case Report ◽  
Soft Tissue ◽  
Pancreatic Necrosis ◽  
Abdominal Mass ◽  
Imaging Findings ◽  
Diagnostic Modality ◽  
Surgical Exploration ◽  
Cystic Masses

A 10-year-old Schnauzer presented with a 1-month history of vomiting, anorexia, and abdominal pain, and a recently detected intra-abdominal mass. The round, soft-tissue opacity masses identified on the radiography in the left mid-abdomen were confirmed as multifocal, cystic masses via ultrasonography. The necrotic masses mimicked an intra-abdominal neoplasia on the initial imaging examinations. The computed tomography (CT) clearly showed encapsulated masses with a necrotic fluid arising from the left limb of the pancreas and extending to the peripancreatic, paracolic, and perigastric regions. Based on the multimodal imaging, surgical exploration, and histopathology, the mass was diagnosed as a walled-off pancreatic necrosis (WOPN). CT is an effective diagnostic modality for diagnosing acute pancreatitis in WOPN.

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