scholarly journals Two vicious circles contributing to a diagnostic delay for tuberculosis patients in Arkhangelsk

2014 ◽  
Vol 7 (1) ◽  
pp. 24909 ◽  
Author(s):  
Vladimir N. Kuznetsov ◽  
Andrej M. Grjibovski ◽  
Andrej O. Mariandyshev ◽  
Eva Johansson ◽  
Gunnar A. Bjune
2020 ◽  
Vol 71 (8) ◽  
pp. 1973-1976 ◽  
Author(s):  
Bianca Sossen ◽  
Tobias Broger ◽  
Andrew D Kerkhoff ◽  
Charlotte Schutz ◽  
Andre Trollip ◽  
...  

Abstract Reducing diagnostic delay is key toward decreasing tuberculosis-associated deaths in people living with human immunodeficiency virus. In tuberculosis patients with retrospective urine testing, the point-of-care Fujifilm SILVAMP TB LAM (FujiLAM) could have rapidly diagnosed tuberculosis in up to 89% who died. In FujiLAM negative patients, the probability of 12-week survival was 86–97%.


Infection ◽  
2010 ◽  
Vol 38 (6) ◽  
pp. 433-446 ◽  
Author(s):  
L. M. Verhagen ◽  
R. Kapinga ◽  
K. A. W. L. van Rosmalen-Nooijens

Author(s):  
Jebamalar J. ◽  
Priya Senthilkumar ◽  
Mary Ramola

Background: Health seeking behaviour has been identified as a complex and dynamic process which influences disease burden of tuberculosis. The present study aimed to study health seeking behaviour among pulmonary tuberculosis patients in a metropolitan city and to assess diagnostic and treatment delays and their determinants.Methods: A cross sectional study was conducted among newly diagnosed pulmonary tuberculosis patients registered for intensive phase of Category 1 ATT during the study period in Zone VIII of Chennai Corporation. The sample size was 197. The study was conducted over a period of one year from September 2015 to August 2016. A standardized WHO interview schedule on diagnostic delay was used for the study.Results: Patients sought healthcare for more severe symptoms like hemoptysis (delay of 38 days) earlier than for cough (delay o- 8 days). Other reasons for delay in seeking care were hope of self-resolution, financial constraints, fear of what the diagnosis would be, incompatible timings etcetera. The total mean delay from onset of symptoms till start of treatment was around 47 days, out of which the patient delay was 42 days. Factors significantly associated with delay included smoking, age more than 35 years and not approaching healthcare facilities first.Conclusions: An unacceptably high patient delay is the major contributor to total delay in the diagnosis and treatment of pulmonary tuberculosis patients. There is increased odds of delay among smokers compared to those who have never smoked. So smokers may be added to the high risk group for suspicion of tuberculosis for fast tracking of diagnosis and treatment. Furthermore, methods to curb over the counter medications should be explored.


2018 ◽  
Vol 146 (12) ◽  
pp. 1511-1518 ◽  
Author(s):  
M. G. Loutet ◽  
C. Sinclair ◽  
N. Whitehead ◽  
C. Cosgrove ◽  
M. K. Lalor ◽  
...  

AbstractImproving access to tuberculosis (TB) care and ensuring early diagnosis are two major aims of the WHO End TB strategy and the Collaborative TB Strategy for England. This study describes risk factors associated with diagnostic delay among TB cases in England. We conducted a retrospective cohort study of TB cases notified to the Enhanced TB Surveillance System in England between 2012 and 2015. Diagnostic delay was defined as more than 4 months between symptom onset and treatment start date. Multivariable logistic regression was used to identify demographic and clinical factors associated with diagnostic delay. Between 2012 and 2015, 22 422 TB cases were notified in England and included in the study. A third (7612) of TB cases had a diagnostic delay of more than 4 months. Being female, aged 45 years and older, residing outside of London and having extra-pulmonary TB disease were significantly associated with a diagnostic delay in the multivariable model (aOR = 1.2, 1.2, 1.2, 1.3, 1.8, respectively). This study identifies demographic and clinical factors associated with diagnostic delay, which will inform targeted interventions to improve access to care and early diagnosis among these groups, with the ultimate aim of helping reduce transmission and improve treatment outcomes for TB cases in England.


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