scholarly journals Predicting the impact of patient and private provider behavior on diagnostic delay for pulmonary tuberculosis patients in India: A simulation modeling study

PLoS Medicine ◽  
2020 ◽  
Vol 17 (5) ◽  
pp. e1003039 ◽  
Author(s):  
Sarang Deo ◽  
Simrita Singh ◽  
Neha Jha ◽  
Nimalan Arinaminpathy ◽  
Puneet Dewan
Infection ◽  
2008 ◽  
Vol 36 (4) ◽  
pp. 335-340 ◽  
Author(s):  
C.-S. Wang ◽  
H.-C. Chen ◽  
C.-J. Yang ◽  
W.-Y. Wang ◽  
I.-W. Chong ◽  
...  

2020 ◽  
Author(s):  
Han Nguyen ◽  
Khan Mai Xuan ◽  
Tuan Nguyen Chi ◽  
Tung Nguyen Thanh ◽  
Quyet Do

Abstract Background: According to the Global Tuberculosis Report 2019, Vietnam is one of the 20 countries with the highest TB prevalence in the world. Pulmonary tuberculosis has a significant effect on lung functions, causing many obstacles in daily activities and affects the quality of patient’s lives.Methods: The case-series study conducted on 43 newly-diagnosed pulmonary tuberculosis patients at the Department of Tuberculosis - Military Hospital 103 within 4 months. The aims of the current study were to evaluate the validity of the Vietnamese version of the St. George's Respiratory Questionnaire and to investigate the relationship between SGRQ scores and the clinical and subclinical symptoms in new pulmonary tuberculosis patients.Results: The results indicate that Vietnamese version of the SGRQ has high reliability with Cronbach's alpha of Total score was 0.9451, Cronbach's alpha of all domains was above 0.6, of which the Symptom domain was 0.6635, the Impact domain was 0.9069, the Activity domain was 0.9121. The study also showed that SGRQ score was proportional to the aggregate size of all cavities on chest X-ray (r = 0.3772) and inversely proportional to BMI (r = -0.2843), MGIT days to positivity (r = -0.1635).Conclusions: The Vietnamese version of the SGRQ is a highly reliable and valuable questionnaire in assessing symptoms and life effects in new PTB patients. We recommend it as symptom measurement and quality of life evaluation in patients with new PTB in future studies.Trial registration: The study protocol was approved by the Ethical Review Board Committee of Vietnam Military Medical University (IRB No. 250/2020/QĐ-HVQY) and by the local ethics committee of Military hospital 103. All participants had provided written informed consents for this study.


2018 ◽  
Vol 25 (1) ◽  
pp. 36-44
Author(s):  
Suryani Suryani ◽  
S. Effendi ◽  
Refin Herizon

The impact and dangers  of  Pulmonary Tuberculosis  incidence is causing death. In Bengkulu province in 2011 there were 1.565 cases of  pulmonary  tuberculosis in 2012  there were 1,670 cases of pulmonary tuberculosis in 2013 there were 2.671 cases of pulmonary tuberculosis and in 2014 there were 2.014 cases of pulmonary tuberculosis this showed that pulmonary tuberculosis was still high. The purpose of this study was to study the relationship of PMO role with                         the success of the treatment of pulmonary tuberculosis patients in working area of Sukamerindu Public Health Center Bengkulu. The type of research used was                 an analytic survey, with Cross Sectional research design. Population in this research was all patient of pulmonary tuberculosis in working area of  Sukamerindu Public Health Center Bengkulu which had treatment 5 months amounted to 36 people in 2015. Samples taken by using total sampling which amounted to 36 people. Data analysis was done by univariate and bivariate analysis using uni Chi-Square (χ2). The results of this study were 41 patients with pulmonary tuberculosis,  20 people (55.6%)  had good role of  PMO, and there were 30 people (83.3%) who had successful treatment, there was a significant relationship between the role of PMO with successful treatment of patients with pulmonary tuberculosis with moderate category. It was  suggested to the related institution to improve and supervise the cadre of  (PMO) so that the success of   the treatment of pulmonary tuberculosis will  increasing. Keywords : drug  supervisor (PMO), successful  treatment, pulmonary  tuberculosis  patients 


Author(s):  
Jebamalar J. ◽  
Priya Senthilkumar ◽  
Mary Ramola

Background: Health seeking behaviour has been identified as a complex and dynamic process which influences disease burden of tuberculosis. The present study aimed to study health seeking behaviour among pulmonary tuberculosis patients in a metropolitan city and to assess diagnostic and treatment delays and their determinants.Methods: A cross sectional study was conducted among newly diagnosed pulmonary tuberculosis patients registered for intensive phase of Category 1 ATT during the study period in Zone VIII of Chennai Corporation. The sample size was 197. The study was conducted over a period of one year from September 2015 to August 2016. A standardized WHO interview schedule on diagnostic delay was used for the study.Results: Patients sought healthcare for more severe symptoms like hemoptysis (delay of 38 days) earlier than for cough (delay o- 8 days). Other reasons for delay in seeking care were hope of self-resolution, financial constraints, fear of what the diagnosis would be, incompatible timings etcetera. The total mean delay from onset of symptoms till start of treatment was around 47 days, out of which the patient delay was 42 days. Factors significantly associated with delay included smoking, age more than 35 years and not approaching healthcare facilities first.Conclusions: An unacceptably high patient delay is the major contributor to total delay in the diagnosis and treatment of pulmonary tuberculosis patients. There is increased odds of delay among smokers compared to those who have never smoked. So smokers may be added to the high risk group for suspicion of tuberculosis for fast tracking of diagnosis and treatment. Furthermore, methods to curb over the counter medications should be explored.


2020 ◽  
Vol 12 (3) ◽  
pp. 181
Author(s):  
Sheilla Mufidha Wahyuningtyas ◽  
Endang Sri Lestari ◽  
Jojok Mukono ◽  
Endro Sukmono

Introduction: Tuberculosis (TB) is a global health crisis. Environmental health services in Primary health care provide counseling services, inspections and environmental health interventions. Research aims to determine the impact of environmental health services in Primary health care on the behavior of TB patients that includes the knowledge, attitudes and actions of pulmonary tuberculosis patients in the prevention of the transmission of pulmonary tuberculosis disease. Method: The method in this study was experimental quasi. Respondents were a new case of pulmonary TB at 6 Primary health care in Banyuwangi Regency April S/d June 2019. Pre test before obtaining environmental health services. Post test was given after counseling, inspection and environmental health intervention. Result and Discussion: The results showed a total of 24 respondents to the majority pulmonary tuberculosis patient was male (54.17%). Pre test knowledge of pulmonary TB patient is good (4.16%), enough (8.33%) and less (87.50%). Category Post test knowledge of TB patients acquired good (20.83%), sufficient category (75.00%) and less (4.20%). The average Pre test knowledge score is 37.70 and the Post test is 67.20. Category Prettest Action patients TB is good (4.16%) and less (95.83%). Category Post Test action patients pulmonary TB is good (54.17%), enough (41.67%) and less (4.16%) Which is an improvement in the form of masks, hand washing soap, the habit of spitting, the use of individual cutlery and drinking equipment, washing dinnerware and drinking with hot water/drying, drying the sleeping tools, opening a window every day, separate sleeping habits. Conclusion: The conclusion of this research is environmental health services in Primary health care in patients with pulmonary tuberculosis improves the behavior of TB patients in the form of increased knowledge, attitudes and actions of the patient in the prevention of disease transmission of TB.


Author(s):  
Anass Benali ◽  
Anass Benali ◽  
Ismail Abderrahmani Rhorfi ◽  
Hicham Souhi ◽  
Hanane El Ouazzani ◽  
...  

Methods: We report a retrospective study analysing the characteristics of pulmonary tuberculosis in patients with pulmonary tuberculosis with heart disease and in tuberculosis patients with no obvious history, treated in the pulmonology department between 2017 and June 2020. Results: Tuberculosis patients with heart disease present more extensive forms than patients without a history (p <0.001), with more occurrence of treatment failure and sequelae (p = 0.01), and more risk of death compared to the control group without heart disease but without significant difference compared to the literature. While the two groups did not differ in terms of cure and negativation of bacteriological tests after two months of treatment (p> 0.05). Conclusion: Heart disease has a significant impact on the history of pulmonary tuberculosis therefore they affect the quality of life of patients.


2018 ◽  
Author(s):  
Nimalan Arinaminpathy ◽  
Sarang Deo ◽  
Simrita Singh ◽  
Sunil Khaparde ◽  
Raghuram Rao ◽  
...  

AbstractIn India, the country with the world’s largest burden of tuberculosis (TB), most patients first seek care in the private healthcare sector, which is fragmented and unregulated. Ongoing initiatives are demonstrating effective approaches for engaging with this sector, and form a central part of India’s recent National Strategic Plan: here we aimed to address their potential impact on TB transmission in urban settings, when taken to scale. We developed a mathematical model of TB transmission dynamics, calibrated to urban populations in Mumbai and Patna, two major cities in India where pilot interventions are currently ongoing.We found that, when taken to sufficient scale to capture 75% of patient-provider interactions, the intervention could reduce incidence by upto 21.3% (95% Bayesian credible interval (CrI) 13.0 – 32.5%) and 15.8% (95% CrI 7.8 – 28.2%) in Mumbai and Patna respectively, between 2018 and 2025. There is a stronger impact on TB mortality, with a reduction of up to 38.1% (95% CrI 20.0 – 55.1%) in the example of Mumbai. The incidence impact of this intervention alone may be limited by the amount of transmission that has already occurred by the time a patient first presents for care: model estimates suggest an initial patient delay of 4-5 months before first seeking care, followed by a diagnostic delay of 1-2 months before ultimately initiating TB treatment. Our results suggest that the transmission impact of such interventions could be maximised by additional measures to encourage early uptake of TB services.


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