Comparison of contrast sensitivity between three aspheric acrylic monofocal intraocular lenses: a prospective randomised trial

Chin Chiet Ying Alice; Banumathi Gurusamy; Lim Keat Andrew; Mae-Lynn Catherine Bastion

doi:10.35119/myjo.v1i4.77

Comparison of contrast sensitivity between three aspheric acrylic monofocal intraocular lenses: a prospective randomised trial

Malaysian Journal of Ophthalmology ◽

10.35119/myjo.v1i4.77 ◽

2020 ◽

Vol 1 (4) ◽

pp. 259-283

Author(s):

Chin Chiet Ying Alice ◽

Banumathi Gurusamy ◽

Lim Keat Andrew ◽

Mae-Lynn Catherine Bastion

Keyword(s):

Cataract Surgery ◽

Contrast Sensitivity ◽

Marked Improvement ◽

Spherical Aberration ◽

Controlled Trial ◽

Randomised Trial ◽

Intraocular Lenses ◽

Aspherical Lens ◽

Spatial Frequencies ◽

Significant Difference

Introduction: Evolution of cataract surgery and implantation of intraocular lenses (IOL) with new technological designs to optimise functional vision has been the aim of cataract surgery today. Aspherical lens design is a new lens technology to counteract spherical aberration exerted by a conventional IOL. Purpose: To compare the contrast sensitivity after cataract surgery between aspheric IOLs with negative spherical aberration (Tecnis ZA9003TM and AcrySof IQTM) and zero spherical aberration IOLs (Akreos Adapt Advance Optic [AO]TM). Study design: Interventional, single-blinded, randomised controlled trial. Methods: Ninety-six patients were recruited with 32 eyes in each study arm. All patients underwent standard phacoemulsification with implantation of an aspheric acrylic IOL randomised to one of the three lens models by a single experienced surgeon. Pre- and postoperative contrast sensitivity was analysed using the CSV1000E chart under photopic and mesopic conditions with and without glare testing. Results: All three lenses showed statistically significant improvement in contrast sensitivity postoperatively at all spatial frequencies under photopic, mesopic, and scotopic conditions with glare. There was no statistically significant difference between the groups. Tecnis ZA9003TM showed marked improvement in mesopic contrast sensitivity at 18 cycles/degree (cpd) at 12 weeks (p < 0.05). The zero aberration Akreos Adapt AOTM showed better photopic contrast sensitivity compared to mesopic contrast sensitivity (p > 0.05). Conclusion: AcrySof IQTM, Akreos Adapt AOTM, and Tecnis ZA9003TM performed equally well in contrast sensitivity at all spatial frequencies under photopic and mesopic conditions with and without glare testing. All lenses had statistically significant improvement in contrast sensitivity after cataract surgery. The negative aberration IOL Tecnis ZA9003TM showed marked improvement in mesopic contrast sensitivity at 18 cpd at 12 weeks. The zero aberration IOL, Akreos Adapt AOTM showed better photopic contrast sensitivity compared to mesopic contrast sensitivity.

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Influence of Intraocular Lens Asphericity and Blue Light Filtering on Visual Outcome, Contrast Sensitivity, and Aberrometry after Uneventful Cataract Extraction

Journal of Ophthalmic and Vision Research ◽

10.18502/jovr.v15i3.7449 ◽

2020 ◽

Author(s):

Argyrios Tzamalis ◽

Myron Kynigopoulos ◽

Grigoris Pallas ◽

Ioannis Tsinopoulos ◽

Nikolaos Ziakas

Keyword(s):

Cataract Surgery ◽

Contrast Sensitivity ◽

Blue Light ◽

Visual Outcome ◽

Cataract Extraction ◽

Light Filter ◽

Intraocular Lenses ◽

Visual Performance ◽

Spatial Frequencies ◽

Significant Difference

Purpose: To evaluate the effect of asphericity and blue light filter (BLF) of three different intraocular lenses (IOLs) on the visual performance, second- and third-order aberrations (defocus, coma, trefoil), and contrast sensitivity after uneventful cataract surgery. Methods: One hundred and twenty eyes of 60 patients with clinically significant cataract were randomly assigned to receive one of the three IOL types: Bioline Yellow Accurate (aspheric, with BLF, i-medical, Germany), BioAcryl 60125 (spherical, without BLF, Biotech, France), and H65C/N (aspheric, without BLF, PhysIOL, Belgium). Each IOL was implanted in 40 eyes. Complete ophthalmologic examination, functional acuity contrast testing and wavefront analysis were performed 60 days postoperatively. Results: The mean postoperative best-corrected visual acuity (BCVA) was 0.95 ± 0.08, not differing statistically among the IOL groups (P = 0.83). Mean defocus and coma values did not yield any statistically significant difference through the IOL groups varying from –0.784 to –0.614 μm and 0.129 to 0.198 μm (P = 0.79 and 0.34, respectively). Bioline Yellow Accurate IOL presented less trefoil aberrations, 0.108 ± 0.05 μm, compared to the other two IOL types (BioAcryl [0.206 ± 0.19 μm] and Physiol [0.193 ± 0.17 μm], P < 0.05). Contrast sensitivity values did not differ among the groups under all lighting conditions. Bioline Yellow IOL showed a statistically higher loss of contrast sensitivity (between mesopic and mesopic with glare conditions) compared to the BioAcryl and PhysIOL in 12 and 3 cpd spatial frequencies, respectively (P < 0.05). Conclusion: Bioline Yellow IOL indicated lower contrast sensitivity under mesopic conditions when glare was applied but resulted in less trefoil aberrations after uneventful cataract surgery. No further differences were noted in postoperative visual performance among three IOL groups.

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Aspheric Intraocular Lenses Implantation for Cataract Patients with Extreme Myopia

ISRN Ophthalmology ◽

10.1155/2014/403432 ◽

2014 ◽

Vol 2014 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Yanwen Fang ◽

Yi Lu ◽

Aizhu Miao ◽

Yi Luo

Keyword(s):

Contrast Sensitivity ◽

Visual Quality ◽

Intraocular Lenses ◽

Wavefront Aberrations ◽

Spatial Frequencies ◽

Aspheric Iol ◽

Significant Difference ◽

Composite Scores ◽

Cataract Patients

Objective. To evaluate the postoperative visual quality of cataract patients with extreme myopia after implantation of aspheric intraocular lenses (IOLs). Methods. Thirty-three eyes were enrolled in this prospectivestudy. Eighteen eyes with an axial length longer than 28 mm were included in the extreme myopia group, and the other 15 eyes were included in the nonextreme myopia group. Phacoemulsification and aspheric IOL implantation were performed. Six months after cataract surgery, best-corrected visual acuity (BCVA), contrast sensitivity, and wavefront aberrations were measured, and subjective visual quality was assessed. Results. The BCVA improved significantly after surgery for both groups, and patients in the nonextreme myopia group achieved better postoperative BCVA due to better retinal status of the eyes. The evaluation of contrast sensitivity without glare was the same in both groups, whereas patients in the nonextreme myopia group performed better at intermediate spatial frequencies under glare conditions. The two groups did not show a significant difference in high-order aberrations. With regard to subjective visual quality, the composite scores of both groups did not differ significantly. Conclusions. Aspheric IOLs provided good visual outcomes in cataract patients with extreme myopia. These patients should undergo careful evaluation to determine the maculopathy severity level before surgery.

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Visual performance of four types of diffractive multifocal intraocular lenses and a review of articles

International Journal of Ophthalmology ◽

10.18240/ijo.2021.03.04 ◽

2021 ◽

Vol 14 (3) ◽

pp. 356-365

Author(s):

Farideh Doroodgar ◽

◽

Azad Sanginabadi ◽

Farid Karimian ◽

Sana Niazi ◽

...

Keyword(s):

Visual Acuity ◽

Contrast Sensitivity ◽

Intraocular Lenses ◽

Multifocal Intraocular Lenses ◽

Spatial Frequencies ◽

Signed Rank ◽

Pubmed Database ◽

Significant Difference ◽

The One ◽

Post Hoc

AIM: To compare the clinical outcomes of a variety of multifocal intraocular lenses (MIOLs) in patients diagnosed with presbyopia or cataracts. METHODS: This clinical trial study included 141 patients (282 eyes) with different MIOLs implantation. The Symfony (60 eyes), the ReSTOR (100 eyes), the AT LISAtri (60 eyes), and the PanOptix (62 eyes) intraocular lenses were evaluated in this prospective interventional study. The near, intermediate, and distant visual acuities, contrast sensitivity, and defocus curve were measured as valid criteria. To statistically analyze the results, we used the Statistical Package for Social Science software, the non-parametric Wilcoxon signed-rank t, the one-way analysis of variance and the Tukey's post-hoc test in our analysis. Moreover, we conducted a detailed literature search on the PubMed database in English about MIOLs, in total 59 studies were included in this review article. RESULTS: The four approaches did not show any significant difference in the best-corrected distance visual acuity (P>0.05). The defocus curves at the contrast of 100% showed that trifocal IOLs had better intermediate performance than the bifocal IOL (P<0.05). There were no statistically significant differences between AT LISAtri and PanOptix lenses for visual acuity at all distances. The eyes with PanOptix, Symfony, and AT LISAtri IOL showed better contrast sensitivity than those ReSTOR at spatial frequencies of 1, 3, and 6 cpd in photopic and mesopic conditions (P<0.001). CONCLUSION: All four groups of the multifocal lenses were satisfying in terms of distance and near vision. Also, the group of trifocal lenses led to satisfactory outcomes in intermediate vision, without degradation in quality of vision.

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Visual Function and Subjective Quality of Life in Chinese Cataract Patients after Implantation with Aspheric Intraocular Lenses

European Journal of Ophthalmology ◽

10.5301/ejo.2011.6441 ◽

2011 ◽

Vol 21 (6) ◽

pp. 732-740

Author(s):

Yanwen Fang ◽

Yi Lu ◽

Xinhua Wu ◽

Aizhu Miao ◽

Yi Luo

Keyword(s):

Visual Acuity ◽

Contrast Sensitivity ◽

Visual Function ◽

Spherical Aberration ◽

Visual Quality ◽

Intraocular Lenses ◽

Subjective Quality Of Life ◽

Significant Difference ◽

The Mean ◽

Cataract Patients

Purpose. To evaluate and compare the objective and subjective visual function after implantation of 2 aspheric intraocular lenses (IOLs) in Chinese cataract patients. Methods. Forty-one eyes of 28 patients with cataract were randomly assigned to receive either the MC X11 ASP IOL or the AcrySof IQ IOL. Three months postoperatively, best-corrected visual acuity (BCVA), contrast sensitivity, wavefront aberrations, and subjective visual quality were measured. The degree of posterior capsule opacification (PCO) was recorded at last follow-up. Results. Postoperative mean monocular BCVA was 0.05±0.13 logMAR in the MC X11 group and 0.05±0.08 logMAR in the IQ group. There was no significant difference in visual acuity, contrast sensitivity, subjective visual quality, and degree of PCO between the 2 groups. For a 6-mm pupil diameter, the mean spherical aberration (Z40) was 0.075±0.076 μm in the MC X11 group and 0.056±0.111 μm in the IQ group. However, 45.5% and 57.9% of the eyes in the MC X11 and IQ groups had values >0.10 μm, respectively. The mean RMS values of the high-order aberrations were similar between the 2 groups except the higher fifth- and sixth-order aberrations, which were significantly higher in the MC X11 group. Conclusions. Both IOLs provided similar and good visual outcomes. However, the data suggest that the amount of negative spherical aberration generated by current available aspheric IOLs might not be optimal for Chinese eyes.

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Efficacy and safety of extended depth of focus intraocular lenses in cataract surgery: a systematic review and meta-analysis

10.21203/rs.2.11472/v2 ◽

2019 ◽

Author(s):

Jing Liu ◽

Yi Dong ◽

Yan Wang

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Intraocular Lenses ◽

Control Group ◽

Efficacy And Safety ◽

Depth Of Focus ◽

Extended Depth Of Focus ◽

Significant Difference ◽

Near Visual Acuity

Abstract Background : This study aims to evaluate the efficacy and safety of extended depth of focus (EDOF) intraocular lenes (IOLs) in cataract surgery. Methods: All comparative clinical trials that involved bilaterally implanting EDOF IOLs in patients with cataract were retrieved from the literature database. We used random effects models to pool weighted mean differences (WMD) and risk ratio (RR) for continuous and dichotomous variables, respectively. Results: Nine studies with a total of 1336 eyes were identified. The subgroup analysis was conducted according to the type of IOLs used in the control group. Compared with monofocal IOLs, EDOF IOLs produced better uncorrected intermediate visual acuity (WMD: -0.17, 95% CI: -0.26 to -0.08, P = 0.0001) and uncorrected near visual acuity (WMD: -0.17, 95% CI: -0.21 to -0.12, P < 0.00001). EDOF IOLs resulted in reduced contrast sensitivity, more frequent halos, however, higher spectacle independence (RR: 2.81, 95% CI: 1.06 to 7.46, P = 0.04) than monofocal IOLs. Compared with trifocal IOLs, EDOF IOLs produced worse near visual acuity (MD: 0.10, 95% CI: 0.07 to 0.13, P<0.0001). EDOF IOLs performed better than trifocal IOls in contrast sensitivity, and there were no significant difference in halos and spectacle independence. Serious postoperative complications were rare, with no adverse events were reported in most studies. Conclusions: Increasing the risk of contrast reduction and more frequent halos, EDOF IOLs provided better intermediate and near VAs than monofocal IOLs. At the expense of near vision, patients receiving EDOF IOLs have better contrast sensitivity than those receiving trifocal IOLs. Halo incidence and spectacle independence of EDOF IOLs were similar to those of trifocal IOLs.

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Efficacy and safety of extended depth of focus intraocular lenses in cataract surgery: a systematic review and meta-analysis

10.21203/rs.2.11472/v1 ◽

2019 ◽

Author(s):

Jing Liu ◽

Yi Dong ◽

Yan Wang

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Intraocular Lenses ◽

Control Group ◽

Efficacy And Safety ◽

Depth Of Focus ◽

Extended Depth Of Focus ◽

Significant Difference ◽

Near Visual Acuity

Abstract Background This study aims to evaluate the efficacy and safety of extended depth of focus (EDOF) intraocular lenes (IOLs) in cataract surgery. Methods All comparative clinical trials that involved bilaterally implanting EDOF IOLs in patients with cataract were retrieved from the literature database. We used random effects models to pool weighted mean differences (WMD) and risk ratio (RR) for continuous and dichotomous variables, respectively. Results Nine studies with a total of 1336 eyes were identified. The subgroup analysis was conducted according to the type of IOLs used in the control group. Compared with monofocal IOLs, EDOF IOLs produced better uncorrected intermediate visual acuity (WMD: -0.17, 95% CI: -0.26 to -0.08, P = 0.0001) and uncorrected near visual acuity (WMD: -0.17, 95% CI: -0.21 to -0.12, P < 0.00001). EDOF IOLs resulted in reduced contrast sensitivity, more frequent halos, however, higher spectacle independence (RR: 2.81, 95% CI: 1.06 to 7.46, P = 0.04) than monofocal IOLs. Compared with trifocal IOLs, EDOF IOLs produced worse near visual acuity (MD: 0.10, 95% CI: 0.07 to 0.13, P<0.0001). EDOF IOLs performed better than trifocal IOls in contrast sensitivity, and there were no significant difference in halos and spectacle independence. Conclusions Increasing the risk of contrast reduction and more frequent halos, EDOF IOLs provided better intermediate and near VAs than monofocal IOLs. At the expense of near vision, patients receiving EDOF IOLs have better contrast sensitivity than those receiving trifocal IOLs. Halo incidence and spectacle independence of EDOF IOLs were similar to those of trifocal IOLs.

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Long-term objective and subjective outcomes following bilateral implantation of diffractive bifocal or trifocal intraocular lenses

European Journal of Ophthalmology ◽

10.1177/1120672120926870 ◽

2020 ◽

pp. 112067212092687

Author(s):

Veronica Vargas ◽

Jorge L Alio ◽

Renan F. Oliveira ◽

Antonio Renna ◽

Pilar Yebana

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Intraocular Lens ◽

Study Groups ◽

Intraocular Lenses ◽

Significant Difference ◽

Visual Function Questionnaire ◽

Objective Outcomes ◽

Subjective Outcomes

Objective To evaluate and compare the objective and subjective outcomes after the bilateral implantation of a diffractive bifocal and trifocal intraocular lens. Methods This is a case–control, single-center observational study which included 27 patients; 16 patients were implanted bilaterally with the bifocal AcrySof IQ ReSTOR+3.0D and 11 patients with the trifocal AT LISA tri 839MP. Uncorrected visual acuity at distance, intermediate, and near under mesopic and photopic conditions using ETDRS charts with 10% and 100% contrast, corrected distance visual acuity, and binocular defocus curve in photopic conditions; binocular contrast sensitivity under mesopic and photopic conditions for far and near distances were assessed. The Visual Function Questionnaire-25 questionnaire was used to assess patients' satisfaction. All the measurements were performed 6–24 months after cataract surgery. Results The ReSTOR group had better binocular uncorrected near visual acuity in photopic conditions with low and high contrast charts ( p = 0.040 and p = 0.033, respectively), as well as in far contrast sensitivity measurement under mesopic conditions with a spatial frequency of 3 cycles per degree ( p = 0.034). There was not a significant difference between the two study groups in uncorrected near, intermediate or distance vision under mesopic conditions. The AT LISA tri study group had better subjective outcomes. Conclusion Both intraocular lenses restore visual acuity after cataract surgery. The ReSTOR intraocular lens provides better objective outcomes than the AT LISA tri, although the latter provides better subjective outcomes. The relevance of this study is the evaluation of both objective and subjective outcomes.

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Pediatric Cataract Surgery: Comparison between Ages at Surgery and Contrast Sensitivity Outcomes

Ophthalmologica Indonesiana ◽

10.35749/journal.v43i1.138 ◽

2019 ◽

Vol 43 (1) ◽

pp. 50

Author(s):

Aquirina Caesari Putri ◽

Rozalina Loebis

Keyword(s):

Visual Acuity ◽

Cataract Surgery ◽

Contrast Sensitivity ◽

Cataract Extraction ◽

Significant Negative Correlation ◽

Natural World ◽

P Value ◽

Pediatric Cataract ◽

Low Contrast ◽

Significant Difference

Background: Pediatric cataracts are major causes of children’s blindness. Surgery has proven to be beneficial in terms of visual function prognosis. Contrast sensitivity evaluation after surgery is as important as visual acuity considering that natural world consists of various objects in low-to-medium contrasts. The purpose of this study is to analyze the difference of contrast sensitivity outcomes based on ages at surgery. Method: Retrospective data of children with pediatric developmental cataract from July 2013 to November 2015 were collected. All children who underwent cataract surgery at 60-months-old or less were randomized into two groups, ≤24 months and >24-to-60 months. Contrast sensitivity was then examined with preferential-looking method using Hiding Heidi low-contrast test face chart. The main outcome measures were contrast sensitivity of both groups. Age-at-evaluation, cataract onset, duration of follow-up, duration of deprivation and visual acuity were also noted. Result: Of 14 children (23 eyes), 11 eyes (47,8%) were in ≤24 months group, 12eyes (52,2%) were in >24-to-60 months group. All eyes underwent cataract extraction and similar type of intraocular lens implantation. Mean age-at-surgery was 28,2 months±16,8 (SD). Mean contrast sensitivity for each group was 47,50 %±42,29 and 18,33%±27,38, respectively, with p-value 0,031. Further analysis of Spearman’s correlation test demonstrated significant negative correlation (rs = -0,559; p = 0,006) between the two groups. Conclusion: There was statistically significant difference in contrast sensitivity between those who underwent surgery at ≤24 months and >24-to-60 months. Children who underwent surgery at older ages tend to have better contrast sensitivity afterwards.

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Prediction accuracy of standard and total keratometry by swept-source optical biometer for multifocal intraocular lens power calculation

Scientific Reports ◽

10.1038/s41598-021-84238-1 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Hun Lee ◽

Jae Lim Chung ◽

Young Jun Kim ◽

Jae Yong Kim ◽

Hungwon Tchah

Keyword(s):

Cataract Surgery ◽

Case Series ◽

Intraocular Lenses ◽

Power Calculation ◽

Neutral Position ◽

Swept Source ◽

Refractive Outcomes ◽

Case Series Study ◽

Significant Difference ◽

Optical Biometer

AbstractWe aimed to compare the refractive outcomes of cataract surgery with diffractive multifocal intraocular lenses (IOLs) using standard keratometry (K) and total keratometry (TK). In this retrospective observational case series study, a total of 302 patients who underwent cataract surgery with multifocal IOL implantation were included. Predicted refractive outcomes were calculated based on the current standard formulas and a new formula developed for TK using K and TK, which were obtained from a swept-source optical biometer. At 2-month postoperatively, median absolute prediction errors (MedAEs) and proportion of eyes within ± 0.50 diopters (D) of predicted postoperative spherical equivalent (SE) refraction were analyzed. There was no significant difference between MedAEs or proportion of eyes within ± 0.50D of predicted refraction from K and TK in each formula. In TFNT00 and 839MP IOL cases, there was no difference between MedAEs from K and TK using any formula. In 829MP IOL cases, MedAE from TK was significantly larger than that from K in Barrett Universal II/Barrett TK Universal II (P = 0.033). In 677MY IOL cases, MedAE from TK was significantly larger than that from K in Haigis (P = 0.020) and Holladay 2 (P = 0.006) formulas. In the subgroup analysis for IOL, there was no difference between the proportion of eyes within ± 0.50 D of predicted refraction from K and TK using any formula. TFNT00 and 839MP IOLs were favorable with TK, with 677MY IOL with K and 829MP IOL being in a neutral position, which necessitates the study that investigates the accuracy of the new TK technology.

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