scholarly journals CARE AND TREATMENT OF NEONATAL JOLT IN NEW BORN CHILDREN

2018 ◽  
Vol 28 (2) ◽  
pp. 649-656
Author(s):  
Gordana Panova ◽  
Elena Geleva
Keyword(s):  
General Hospital ◽  
Neonatal Jaundice ◽  
Early Recognition ◽  
Early Stage ◽  
Early Assessment ◽  
Medical Needs ◽  
Yellow Coloration ◽  
Newborn Child ◽  
Independent Life ◽  
The Moment

From the moment we were born, we form a new period of our life. The fetus, whom our mothers carefully nurture throughout the whole pregnancy enters the newborn period. The newborn child has medical needs that are needed to help with this important adaptive period, a team of neonatologists is processing the primary reanimation and postpartal nurture of every child.The quick evaluation of the condition of a newborn child with eventual reanimation procedure is very important to reduce the possible complications & reduce the pathological growth and development of the newborn. As part of that judgement is the condition of most common illness that affects an infant called jaundice, a yellow coloration of the skin caused by accumulation of bilirubin in the skin and the mucous membranes. The birth of new life is a privilege at the gynecological-obstetrician department.Given the importance of early assessment and right primarily reanimation of a newborn, the main objectives of labor are:- What causes the neonatal jaundice at a newborn and the frequency and risk factors of appearance- Following and therapy of neonatal jaundice at an early stage- Determination how serious the jaundice is affecting the newborn- The percentage of infants affected by neonatal jaundice, and possible outcome.Material and methods:In this paper we have processed the data of gynecological- obstetrician department of JZU General Hospital- Kumanovo. The period of last year’s 2017 data is covered. As a material evidence we used the registers of newborn babies from the gynecological- obstetrician department of JZU General hospital- Kumanovo throughout the whole year and for processing are taken the medical data of condition in the moment of birth, following the condition of the newborn babies while they are still under supervision of the gynecological- obstetrician department & regular frequent examinations.Results:In total the results of newborn babies in the past year (2017) is 1378, where there are taken early borns and term born babies. Amongst them there are prevented conditions of neonatal jaundice at 58 kids, approximately 4,21% of the total number of newborn babies in 2017,from which 50 newborn babies are born on time & 8 are prematurely born.Conclusion:A necessity is the early recognition of all the causes that could lead to need of primary measures, especially after the birth and the first few weeks when there can be preventive measures for overcoming the occurrence of neonatal jaundice & help the fetus readily start the independent life.

scholarly journals Epidemiological features and medical care-seeking process of patients with COVID-19 in Wuhan, China

2020 ◽  
Vol 6 (2) ◽  
pp. 00142-2020 ◽  
Author(s):  
Jing Hua ◽  
Rongzhang Chen ◽  
Liming Zhao ◽  
Xiaodong Wu ◽  
Qian Guo ◽  
...  
Keyword(s):  
Medical Care ◽  
Early Recognition ◽  
Early Stage ◽  
Evaluation Process ◽  
Clinical Information ◽  
Healthcare Setting ◽  
Care Seeking ◽  
Medical Visit ◽  
Illness Onset ◽  
Clinical Recovery

BackgroundWe aimed to investigate the epidemiological and clinical features, and medical care-seeking process of patients with the 2019 coronavirus disease (COVID-19) in Wuhan, China, to provide useful information to contain COVID-19 in other places with similar outbreaks of the virus.MethodsWe collected epidemiological and clinical information of patients with COVID-19 admitted to a makeshift Fangcang hospital between 7 and 26 February, 2020. The waiting time of each step during the medical care-seeking process was also analysed.ResultsOf the 205 patients with COVID-19 infection, 31% had presumed transmission from a family member. 10% of patients had hospital-related transmission. It took as long as a median of 6 days from the first medical visit to receive the COVID-19 nucleic acid test and 10 days from the first medical visit to hospital admission, indicating early recognition of COVID-19 was not achieved at the early stage of the outbreak, although these delays were shortened later. After clinical recovery from COVID-19, which took a mean of 21 days from illness onset, there was still a substantial proportion of patients who had persistent SARS-CoV-2 infection.ConclusionsThe diagnostic evaluation process of suspected patients needs to be accelerated at the epicentre of the outbreak and early isolation of infected patients in a healthcare setting rather than at home is urgently required to stop the spread of the virus. Clinical recovery is not an appropriate criterion to release isolated patients and as long as 4 weeks' isolation for patients with COVID-19 is not enough to prevent the spread of the virus.

scholarly journals P300 and Decision Making under Risk and Ambiguity

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Lei Wang ◽  
Jiehui Zheng ◽  
Shenwei Huang ◽  
Haoye Sun
Keyword(s):  
Decision Making ◽  
Early Stage ◽  
Event Related Potentials ◽  
Underlying Mechanism ◽  
P300 Amplitude ◽  
Early Assessment ◽  
Decision Making Under Risk ◽  
Related Potentials ◽  
The Difference ◽  
Ambiguous Condition

Our study aims to contrast the neural temporal features of early stage of decision making in the context of risk and ambiguity. In monetary gambles under ambiguous or risky conditions, 12 participants were asked to make a decision to bet or not, with the event-related potentials (ERPs) recorded meantime. The proportion of choosing to bet in ambiguous condition was significantly lower than that in risky condition. An ERP component identified as P300 was found. The P300 amplitude elicited in risky condition was significantly larger than that in ambiguous condition. The lower bet rate in ambiguous condition and the smaller P300 amplitude elicited by ambiguous stimuli revealed that people showed much more aversion in the ambiguous condition than in the risky condition. The ERP results may suggest that decision making under ambiguity occupies higher working memory and recalls more past experience while decision making under risk mainly mobilizes attentional resources to calculate current information. These findings extended the current understanding of underlying mechanism for early assessment stage of decision making and explored the difference between the decision making under risk and ambiguity.

scholarly journals Palate: The App for Finding Restaurant Faster

2021 ◽  
Author(s):  
Patrick Gioseffi
Keyword(s):  
Mobile Application ◽  
Early Stage ◽  
Design Principles ◽  
Major Research ◽  
Research Project ◽  
On Demand ◽  
Current Process ◽  
The Moment ◽  
The Impact

This Major Research Project (MRP) aims to investigate the impact of the on-demand economy, millennials’ digital habits, and the emergence of super apps on the restaurant-finding process. Currently, restaurant-goers are presented with multiple specialty applications to complete different tasks when evaluating restaurants. The current process of deciding on a restaurant is both time-consuming and inefficient. This project aims to propose a solution to this problem in the form of an early-stage super app called Palate. Palate is a mobile application that aims to streamline the process of discovering restaurants from the moment a restaurant-goer begins their search to the moment they confirm a reservation. This paper will discuss design principles, theories of the on-demand economy, restaurant-goers digital habits, super apps and the rationale for designing a restaurant super app interface.

scholarly journals Glucocorticoid-Induced Avascular Bone Necrosis: Diagnosis and Management

2012 ◽  
Vol 6 (1) ◽  
pp. 449-457 ◽  
Author(s):  
KL Chan ◽  
CC Mok
Keyword(s):  
Early Recognition ◽  
Early Stage ◽  
Weight Bearing ◽  
Plain Radiograph ◽  
Core Decompression ◽  
Bone Necrosis ◽  
Avascular Bone Necrosis ◽  
Magnetic Resonance Imaging Mri ◽  
High Index Of Suspicion

Glucocorticoid use is one of the most important causes of avascular bone necrosis (AVN). The pathogenesis of glucocorticoid-induced AVN is not fully understood but postulated mechanisms include fat hypertrophy, fat emboli and intravascular coagulation that cause impedance of blood supply to the bones. Data regarding the relationship between AVN and dosage, route of administration and treatment duration of glucocorticoids are conflicting, with some studies demonstrating the cumulative dose of glucocorticoid being the most important determining factor. Early recognition of this complication is essential as the prognosis is affected by the stage of the disease. Currently, there is no consensus on whether universal screening of asymptomatic AVN should be performed for long-term glucocorticoid users. A high index of suspicion should be exhibited for bone and joint pain at typical sites. Magnetic resonance imaging (MRI) or bone scintigraphy is more sensitive than plain radiograph for diagnosing early-stage AVN. Conservative management of AVN includes rest and reduction of weight bearing. Minimization of glucocorticoid dose or a complete withdrawal of the drug should be considered if the underlying conditions allow. The efficacy of bisphosphonates in reducing the rate of collapse of femoral head in AVN is controversial. Surgical therapy of AVN includes core decompression, osteotomy, bone grafting and joint replacement. Recent advances in the treatment of AVN include the use of tantalum rod and the development of more wear resistant bearing surface in hip arthroplasty.

scholarly journals Plasma lactate levels and lactate clearance as predictors of outcome in patients with sepsis and septic shock

2020 ◽  
Vol 7 (6) ◽  
pp. 1213
Author(s):  
Rashmi Patil ◽  
Chikkanarasareddy P. S. ◽  
Mallesh K.
Keyword(s):  
Septic Shock ◽  
Clinical Decision Making ◽  
Early Recognition ◽  
Early Stage ◽  
Therapeutic Option ◽  
Lactate Clearance ◽  
Plasma Lactate ◽  
Risk Of Death ◽  
Lactate Levels ◽  
Sepsis And Septic Shock

Background: Severe sepsis and septic shock are the major causes of admission and deaths in the ICU, killing one in four (and often more) and increasing in incidence. In order to improve the clinical outcomes in these patients, it is crucial to obtain early recognition of patients who are at risk of death and to optimize the clinical decision making in a timely manner. In order to monitor the metabolic consequences of shock and hemodynamic management, plasma lactate levels can be used in critical illness. Objective of the study is to estimate plasma lactate and lactate clearance in sepsis and septic shock patients and to correlate plasma lactate and lactate clearance as predictors of mortality.Methods: This study is a prospective observational study conducted over 18months. Children with age of 1 month to 18 years admitted to the Paediatric intensive care unit with sepsis and septic shock were enrolled in the study. ABG at admission to document plasma lactate and lactate repeated at 6 and 24 hrs. Lactate clearance calculated at 6 and 24 hrs. The final outcome in terms of survival or death will be recorded.Results: Majority of the children fall in the class between 1-6 months 51(48.11%). Male comprises 69(65.09%). Among these, Sepsis 36(33.96%); followed by Pneumonia 34(32.07%). Survivors group were 35(33.02%) and non-survivor was 71(66.98%). The Non survivor group was observed to have lower mean values of lactate clearance and found to be statistically significant. Specificity of Lactate clearance was 63.52% and Sensitivity 76.02% respectively. The results were positively associated with lactate level at 24 hours found to be significant effect of survivability when compared to non-survivor.Conclusions: Lactate clearance is vital and markable sign for screening of septic shock at early stage for therapeutic option. Further, 24-hours lactate estimation (cut off values) clearance appears superior to 6 h lactate clearance in predicting mortality in such patients.

scholarly journals Observations on the Nutrition of Maggots of Australian Blow-Flies

1933 ◽  
Vol 10 (3) ◽  
pp. 237-246
Author(s):  
M. J. MACKERRAS ◽  
M. R. FRENEY
Keyword(s):  
Early Stage ◽  
Wool Fibre ◽  
Initial Growth ◽  
Full Development ◽  
Adequate Food ◽  
Acid Reaction ◽  
Keratin Hydrolysis ◽  
The Moment ◽  
The Masses ◽  
Two Stages

1. Larvae of L. cuprina and Ch. rufifacies are capable of liquefying and digesting protein media without the intervention of bacteria. Both species and L. sericata secrete tryptic and peptic enzymes and at least L. cuprina does so from the moment of hatching. Tryptase is more abundant than peptase. Predatory activity, though a normal habit of Ch. rufifacies, is not necessary for any of these species and did not occur in the masses of Lucilia larvae used for extraction of the enzymes, although they were kept for periods up to 24 hours without food. 2. Partial development of larvae occurred in sheep dung, faeces-stained wool and in the products of keratin hydrolysis. Complete development took place in wool containing a "gummy crust" of dried exudate and in some samples of faeces-stained wool. Some of the samples of faeces-stained wool and those containing a "crust" have been demonstrated serologically by Dr I. M. Mackerras to have an increased content of soluble sheep protein as compared with normal wool. A marked increase of soluble protein has been demonstrated in struck wool both chemically and serologically. 3. Moisture, warmth, shelter and aeration are essential physical conditions for larval development. In addition, an alkaline reaction is relatively favourable and an acid reaction relatively unfavourable. 4. There are normally two stages in the development of a primary strike, the first stage being from hatching up to the time the larvae attack the skin, the outer layer or epidermis of which is approximately 36µ thick (Whitnall, 1931). During this stage they must feed, if at all, on materials already present. The second stage is from the commencement of an actual skin lesion up to full development of the maggots. During this stage there is a more or less copious serous exudation, which has been shown to be an adequate food for the full development of the maggots. Faeces-staining, presence of exudate due to a prior lesion, and products of wool hydrolysis have been shown to be adequate to carry the larvae through the first stage. Wool hydrolysis on the living sheep is probably not an important factor, judging by an examination of wool samples, but we have isolated organisms which, when growing on a nutrient medium, are capable of disintegrating wool fibre. 5. The rôle of bacterial activity in strike is complex and appears to be substantially as follows: (a) to produce substances which attract the flies and stimulate them to oviposit; (b) to provide food for the initial growth of the maggots, either by rendering assimilable the inert proteins, or by causing a skin reaction with a serous exudation. 6. The immediate work for the future is a more exact determination of: (a) the nature of the food of the larvae in the early stage of growth on the living sheep; (b) the factors which influence its production; and (c) the mechanism by which the larvae invade the skin.

scholarly journals The computer and magnetic resonance imaging in the early assessment of the clinical course of ischemic stroke

2019 ◽  
Vol 18 (2) ◽  
pp. 35-40
Author(s):  
R. Kh. Aldatov ◽  
V. A. Fokin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Ischemic Stroke ◽  
Magnetic Resonance ◽  
Intravenous Thrombolysis ◽  
Neurological Symptoms ◽  
Limiting Factor ◽  
Resonance Imaging ◽  
Early Assessment ◽  
Stage Of Development ◽  
The Moment

The most important benefit that imaging provides to a patient with ischemic stroke is the rapid identification of those patients who are most likely to benefit from emergency treatment. This group includes patients who suffer from severe neurological symptoms due to the occlusion of the main artery, and those who are candidates for recanalization by intravenous thrombolysis or intra-arterial intervention to remove blockage.Objective – to assess the sensitivity and significance of computed tomography and magnetic resonance imaging in early diagnosis of infarction foci.Material and methods. The results of radiologic studies of 89 patients with a clinical picture, suspected of acute ischemic cerebral circulation disorders, received in the first 24 hours from the moment of development of neurological symptoms were analyzed.Results. As a result of our study, it was shown that in the first group of patients received in the first 4.5 h from the moment of development of neurological symptoms of CT-signs of stroke were not detected in 16 (76 %) of 21 patients, while those received in the first 24 h from the moment of development of neurological symptoms of CT-signs of stroke were not detected in 14 (28 %) of 50 patients, determined by the symptom of strengthening of the artery, loss of differentiation between gray and white matter of the brain, smoothness of cortical furrows and the appearance of a zone of reduced densitometric density brain substances (<22HU). The difficulties of diagnosis in some patients on CT were the size and localization of ischemic areas (lacunar, stem strokes). In group II of 18 patients of the study, native MRI revealed signs of ischemic areas in 10 patients out of 10, complex CT and MRI to determined areas of hypoperfusion in 8 patients out of 8.Conclusion. CT is the most widely used imaging technique for cerebral infarction with high sensitivity to intracerebral hemorrhage, high specificity in ischemia, but low sensitivity to the detection of ischemic changes is a limiting factor. The data obtained confirm that MRI is a reliable method of diagnosing ischemic stroke. The most sensitive in the diagnosis of ischemic changes in the acute stage of development by using DWI (b1000).

Early Recognition of Suspicious Activity for Crime Prevention

2018 ◽  
pp. 2139-2165
Author(s):  
M. Kalaiselvi Geetha ◽  
J. Arunnehru ◽  
A. Geetha
Keyword(s):  
Crime Prevention ◽  
Early Recognition ◽  
Early Stage ◽  
Criminal Activity ◽  
Automatic Identification ◽  
Early Prediction ◽  
Interest Point ◽  
Prediction Problem ◽  
Novel Approach ◽  
2D And 3D

Automatic identification and early prediction of suspicious human activities are of significant importance in video surveillance research. By recognizing and predicting a criminal activity at an early stage, regrettable incidents can be avoided. Initially, an action recognition framework is developed for identifying the suspicious actions using interest point based 2D and 3D features and transform based approaches. This is subsequently followed by a novel approach for predicting the suspicious actions for crime prevention in real-world scenario. The prediction problem is formulated probabilistically and a novel approach that employs the mixture models for prediction is introduced. The developed system yields promising results for predicting the actions in real-time.

OP97 Digital Home Services: Overcoming Critical Barriers In Early Decision Making

2018 ◽  
Vol 34 (S1) ◽  
pp. 36-36
Author(s):  
Linn Nathalie Stome ◽  
Arne Norrud ◽  
Martin Fjordholm ◽  
Kari Kvaerner
Keyword(s):  
Decision Making ◽  
Net Present Value ◽  
Early Stage ◽  
Service Needs ◽  
Developmental Phase ◽  
Present Value ◽  
Early Assessment ◽  
Digital Home ◽  
Health Innovations ◽  
Home Based

Introduction:There is a lack of adoption and diffusion of health innovations needed to drive the implementation of important breakthroughs in value-based health care. To stimulate organizational changes, decision-makers need to see potential benefit at an early stage. The aim of the present study was to assess the potential effects of a conceptualized intention to provide digital home-based care and compare it to the current provision of such care. The new intervention aims to strengthen the municipality's care services by offering a digital communication platform to recipients of home-based health services and their dependents. The platform is designed to be implemented nationally and is in line with home service needs identified in several white papers.Methods:An interdisciplinary team united to determine and quantify potential effects of the project. Effects of the digitalized service were distinguished in priced quantitative, unpriced quantitative and qualitative effects. A ten-year present value calculation with a calculation rate of four percent was used for the estimates. A risk analysis was also carried out.Results:The present value calculation resulted in estimated savings equal to EUR 25.8 million , with present value investments costs of EUR 5.5 million over ten years. This resulted in net present value per invested euro in the public sector equal to EUR 3.2. Overall assessment of uncertainty related to the intervention's socio-economic profitability was deemed average. Based on data quantified estimates from the conceptual phase, the project succeeded in the decision-making and funding needed to proceed into the next developmental phase of the project.Conclusions:The present approach to early assessment may provide much desired decision support in an early innovation phase when data are still missing. Our experience is that early stakeholder involvement and the early assessment and quantification of value gains are of utmost importance to overcome the critical barriers to organization health innovations.

scholarly journals Paralytic ileus as the presenting symptom for Guillain–Barré syndrome: a case report

2019 ◽  
Vol 48 (4) ◽  
pp. 030006051989316
Author(s):  
Kuang-Heng Lee ◽  
Tsung-Han Ho ◽  
Jiunn-Tay Lee ◽  
Li-Fan Lin ◽  
Wei-Chou Chang ◽  
...  
Keyword(s):  
Paralytic Ileus ◽  
Early Recognition ◽  
Early Stage ◽  
Immunoglobulin Therapy ◽  
Guillain Barre Syndrome ◽  
Rapid Progression ◽  
Limb Weakness ◽  
Intravenous Immunoglobulin Therapy ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Guillain–Barré syndrome (GBS) is an acute neuroimmunological disorder characterized by rapidly ascending symmetrical limb weakness, areflexia, and sensory deficits. Approximately 65% of patients with GBS present with autonomic dysfunction, which commonly occurs in advanced stages. However, paralytic ileus, a sign of gastrointestinal dysautonomia, is rare as the presenting feature in GBS before motor weakness becomes evident. We report the case of a 54-year-old man admitted to the Emergency Department with paralytic ileus as the prodromal feature in early-stage GBS. Total parenteral feeding and prokinetic use were initiated, but no clinical improvement was observed. The patient showed rapid progression to quadriplegia, which was ultimately determined to be respiratory muscle failure requiring mechanical ventilation and intensive care unit admission. He underwent 5 days of intravenous immunoglobulin therapy and muscle strength was partially improved thereafter. However, the patient’s enteral nutritional support was undesirable because of persistent poor gastric emptying complicated by fungemia and profound sepsis throughout the hospital course. Finally, he died 1 month after admission. Ignorance of this unusual prodrome to GBS could result in delayed treatment, along with potential progression to life-threatening events. Early recognition of GBS and prompt immunotherapy are critical for reducing morbidity and mortality.

Sign in / Sign up

Export Citation Format

Share Document