scholarly journals Nasal Cytology by Nasal Smear and by Nasal Mucosa Smear for Diagnosis of Allergic and Nonallergic Rhinitis

1990 ◽  
Vol 1 (2) ◽  
pp. 75-82
Author(s):  
Byung Woo Joe
Keyword(s):  
Nasal Mucosa ◽  
Nonallergic Rhinitis ◽  
Nasal Cytology

Nasal Cytology in Radiofrequency Turbinate Volume Reduction

ORL ◽  
2021 ◽  
pp. 1-6
Author(s):  
Giancarlo Pecorari ◽  
Giuseppe Riva ◽  
Claudia Bartoli ◽  
Mattia Ravera ◽  
Valeria Dell’Era ◽  
...  
Keyword(s):  
Allergic Rhinitis ◽  
Effective Treatment ◽  
Nasal Obstruction ◽  
Nasal Mucosa ◽  
Inferior Turbinate ◽  
Volume Reduction ◽  
Nonallergic Rhinitis ◽  
Turbinate Hypertrophy ◽  
Nasal Cytology ◽  
Rhinitis Medicamentosa

Introduction: Radiofrequency turbinate volume reduction (RFTVR) is an effective treatment of inferior turbinate hypertrophy. RFTVR can reduce epithelial cell alterations in nasal mucosa. The aim of this observational study was to evaluate the effects of RFTVR on nasal obstruction and cytology, stratifying for different types of rhinitis. Methods: Nasal cytology and subjective nasal obstruction were evaluated on 113 patients before RFTVR (T0) and after 3 months (T1). The patients were divided into groups on the basis of the underlying disease: allergic rhinitis, nonallergic rhinitis, rhinitis medicamentosa, and other diseases (e.g., hormonal-based turbinate hypertrophy). Results: Nasal cytology at T0 identified 42 patients with allergic rhinitis, 40 with nonallergic rhinitis, 19 with rhinitis medicamentosa, and 12 with other diseases. An improvement of nasal cytology at T1 was observed in 29.2% of cases. They mainly consisted of patients with nonallergic rhinitis with neutrophils, whose neutrophil infiltrate decreased. Only 2 cases (1.7%) showed a worsening of nasal cytology at T1. A statistically significant decrease in subjective nasal obstruction was observed for every group (p < 0.05). Higher differences of nasal obstruction between T0 and T1 were found in patients with rhinitis medicamentosa or other diseases. Conclusion: RFTVR represents a safe and effective treatment for turbinate hypertrophy of various etiology. It is not responsible for a worsening of inflammatory infiltrate of the nasal mucosa.

scholarly journals Nasal eosinophils associated with rheumatoid arthritis: description of some clinical cases and review of the literature

2020 ◽  
Author(s):  
Arturo Armone Caruso ◽  
Salvatore Del Prete ◽  
Daniela Marasco ◽  
Liliana Nappi ◽  
Clara Imperatore ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Maintenance Therapy ◽  
Nasal Mucosa ◽  
Respiratory System ◽  
Middle Age ◽  
Review Of The Literature ◽  
Italian Association ◽  
Nasal Cytology

Abstract In this review we describe the relation between nasal eosinophilia and rheumatoid arthritis (RA). Moreover we was performed a literature revision that valued the relation between eosinophilia in respiratory system with arthritis. We have examined, through nasal cytology, 7 patients (5 men and 2 women) aged between 7 and 60 years old, with a middle age of 38,5 years; this patients are affected by RA, members of UO of Diagnostic ORL and nasal cytology of the AIAS (Italian Association of Disadvantages assistance) of Afragola.Between them we put in evidence only a case of youth RA. All patients was not allergic and affected by recurrent rhinitis in maintenance therapy and not related with pollen calendar. The withdrawal documented the presence of rare eosinophils in nasal mucosa. This evidence could induce us to use this practice not only as follow up of patients but also as means of early diagnosis.

Noninfectious, Nonallergic Rhinitis (NINAR): Considerations on Possible Mechanisms

1998 ◽  
Vol 12 (1) ◽  
pp. 65-72 ◽  
Author(s):  
Alvin Sanico ◽  
Alkis Togias
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Mucosa ◽  
Environmental Changes ◽  
Atmospheric Conditions ◽  
Nonallergic Rhinitis ◽  
Sinus Disease ◽  
Neuronal Control ◽  
Perceptual Acuity ◽  
Interesting Development ◽  
Shed Light

Most patients who suffer from chronic noninfectious, nonallergic rhinitis (NINAR) cannot be assigned to a syndrome of known etiology. The symptomatology may well resemble that of allergic rhinitis; however, NINAR has lower prevalence of sneezing, conjunctival symptoms, and pruritus and higher prevalence of symptoms compatible with sinus disease. The triggers for the symptoms of NINAR are mainly irritants and changes in atmospheric conditions. Among individuals who develop chronic rhinitis symptoms, the percentage of nonallergic etiology increases steadily with age and is more than 60% beyond the fifth decade of life. Our strategy regarding the pathophysiology of NINAR should be to identify functional abnormalities of nasal mucosa that can potentially result in the alleged nasal symptoms. In this respect, comparison of patients with NINAR to patients with allergic rhinitis and to healthy individuals could shed light into the cause(s) of NINAR. Three potential functional abnormalities are discussed in this article: those associated with the aging process of the nasal mucosa, those resulting in various forms of nasal hyperreactivity, and those reflecting imbalanced neuronal control of end organs of the nose. The most interesting development in the therapy of NINAR is the use of capsaicin. Although placebo-controlled studies are scarce and participants have not been adequately characterized, it is possible that abnormal nociceptor nerve endings play a role in the generation of the symptoms of NINAR. Alternatively, NINAR may represent a condition of increased perceptual acuity to irritants and to environmental changes. This problem may also benefit from defunctionalization of nociceptors.

scholarly journals Peculiarities of non-allergic rhinitis with eosinophilia syndrome

2015 ◽  
Vol 12 (4) ◽  
pp. 3-7
Author(s):  
V A Utesheva ◽  
G P Bondareva ◽  
A I Kryukov ◽  
T G Barkhina
Keyword(s):  
Allergic Rhinitis ◽  
Nasal Mucosa ◽  
Specific Ige ◽  
Skin Tests ◽  
Eosinophilic Infiltration ◽  
Eosinophilic Inflammation ◽  
Nonallergic Rhinitis ◽  
Provocation Tests ◽  
Nasal Provocation ◽  
Non Allergic Rhinitis

Nonallergic rhinitis with eosinophilia syndrome (NARES) is a syndrome containing the symptoms similar to allergic rhinitis, with absence of atopy and the presence of eosinophila more than 20% in smears from nasal mucosa. Pathophysiology of NARES has not been studied completely, but permanent eosinophilic inflammation is the keystone of NARES pathogenesis. This disease is marked by local eosinophilic infiltration without atopy, confirmed by negative skin tests, normal levels of total and specific IgE in serum, negative nasal provocation tests with allergens. Nowadays this nosology is considered to be poorly understood.

scholarly journals Allergic and nonallergic rhinitis in children: The role of nasal cytology

2013 ◽  
Vol 03 (02) ◽  
pp. 133-138
Author(s):  
Maria Cristina Provero ◽  
Alberto Macchi ◽  
Sara Antognazza ◽  
Maddalena Marinoni ◽  
Luigi Nespoli
Keyword(s):  
Nonallergic Rhinitis ◽  
Nasal Cytology

scholarly journals Nasal eosinophils associated with rheumatoid arthritis: description of some clinical cases and review of the literature

2020 ◽  
Author(s):  
Arturo Armone Caruso ◽  
Salvatore Del Prete ◽  
Daniela Marasco ◽  
Liliana Nappi ◽  
Clara Imperatore ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Early Diagnosis ◽  
Maintenance Therapy ◽  
Nasal Mucosa ◽  
Respiratory System ◽  
Middle Age ◽  
Review Of The Literature ◽  
Italian Association ◽  
Nasal Cytology

Abstract In this review we describe the relation between nasal eosinophilia and rheumatoid arthritis (RA). Moreover we was performed a literature revision that valued the relation between eosinophilia in respiratory system with arthritis. We have examined, through nasal cytology, 7 patients (5 men and 2 women) aged between 7 and 60 years old, with a middle age of 38,5 years; this patients are affected by RA, members of UO of Diagnostic ORL and nasal cytology of the AIAS (Italian Association of Disadvantages assistance) of Afragola.Between them we put in evidence only a case of youth RA. All patients was not allergic and affected by recurrent rhinitis in maintenance therapy and not related with pollen calendar. The withdrawal documented the presence of rare eosinophils in nasal mucosa. This evidence could induce us to use this practice not only as follow up of patients but also as means of early diagnosis.

Nasal Function Changes at High Altitude

2020 ◽  
Vol 34 (5) ◽  
pp. 618-625 ◽  
Author(s):  
Giancarlo Ottaviano ◽  
Ennio Nardello ◽  
Alfonso Luca Pendolino ◽  
Martino Dalla Pozza ◽  
Massimiliano Russo ◽  
...  
Keyword(s):  
High Altitude ◽  
Nasal Mucosa ◽  
Vital Capacity ◽  
Forced Expiratory Volume ◽  
Base Camp ◽  
Sport Activities ◽  
Small Cohort ◽  
Nasal Cytology ◽  
Nasal Function ◽  
Peak Nasal Inspiratory Flow

Background An ever-increasing number of people are involved in sport activities at high altitude. Objective This study aimed to evaluate the pulmonary and nasal functions, including nasal cytology, in healthy volunteers moving for 1 week from an altitude of 2000 m to another of 3400 m. Methods Peak nasal inspiratory flow (PNIF), pulmonary function, including peak expiratory flow (PEF), mucociliary transport time (MCTt), nasal cytology, and oxygen saturation (O2 sat) were studied in 5 different occasions—T1: at base camp (2000 m); T2: at the mountain refuge (3400 m); T3: after 7 days at 3400 m; T4: after the return at the base camp (2000 m); and T5: at the base camp (2000 m) after 15 days. Results With respect to T1, PEF values decreased at T2 ( P = .004), T3 ( P = .004), T4 ( P = .000), and T5 ( P = .001). Forced expiratory volume in the first second and forced vital capacity did not differ among the 5 different times of measurements. In regard to T1, PNIF values increased at T2 ( P = .003) and T3 ( P = .001). MCTt and O2 sat showed similar but opposite changes with MCTt increased at T2 and T3 in respect to T1 ( P = .000 for both), while O2 sat decreased at T2 and T3 in respect to T1 ( P = .000 for both). At nasal cytology, the number of neutrophils increased at T2 in respect to T1 ( P = .008). At multivariate analysis, PNIF changed with altitude from T1 to T4 even accounting for the effect of all the other variables (T1 vs T2 PNIF, P = .009; T1 vs T3 PNIF, P = .007; T1 vs T4 PNIF, P = .021). Conclusions Although the study has some limitations, being conducted on a small cohort and at no controlled environmental conditions, data seem to support the utility of MCTt for studying nasal mucosa damage induced by high altitude. Nasal cytology seems to be able to identify the inflammation of the nasal mucosa exposed to hypoxia. Further investigations on larger series and possibly conducted in hypobaric chamber at controlled standardized conditions are necessary in order to confirm these results and, most importantly, the improvement of PNIF at high altitude.

scholarly journals Correlation of Local FOXP3-Expressing T Cells and Th1-Th2 Balance in Perennial Allergic Nasal Mucosa

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Hideaki Shirasaki ◽  
Etsuko Kanaizumi ◽  
Nobuhiko Seki ◽  
Tetsuo Himi
Keyword(s):  
T Cells ◽  
Allergic Rhinitis ◽  
Regulatory T Cells ◽  
Nasal Mucosa ◽  
Specific Marker ◽  
Nonallergic Rhinitis ◽  
Significant Difference ◽  
Treg Development ◽  
The Relationship

Regulatory T cells (Treg) play some important roles in allergic rhinitis. The most specific marker for Treg is FOXP3, a recently identified transcription factor that is essential for Treg development. In order to clarify the levels of Treg in allergic nasal mucosa, we studied the relationship between FOXP3-expressing cells and Th1-Th2 balance in nasal mucosa by means of immunohistochemistry. Human turbinates were obtained after turbinectomy from 26 patients (14 patients with perennial allergic rhinitis and 12 patients with nonallergic rhinitis). To identify the cells expressing the FOXP3 protein, double immunostaining was performed by using anti-FOXP3 antibody and anti-CD3 antibody. There was no significant difference in the percentage of FOXP3+CD3+ cells among CD3+ cells in the nasal mucosa of two groups. The proportion of FOXP3+CD3+ cells tend to be correlated positively with GATA3+CD3+ cells/T-bet+CD3+ cells ratio (, ). A positive correlation with GATA3+CD3+/T-bet+CD3+ ratio and FOXP3+CD3+/CD3+ ratio suggests the role of local regulatory T cells as a minimal control of the chronic allergen exposure in nasal mucosa.

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