scholarly journals Urine Albumin Creatinine Ratio Among Diabetic Retinopathy Patient With And Without Diabetic Macular Edema In Moh. Hoesin Hospital Palembang

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Rina Astuti ◽  
AK Ansyori ◽  
Ramzi Amin
Keyword(s):  
Risk Factors ◽  
Diabetic Retinopathy ◽  
High Density Lipoprotein ◽  
Macular Edema ◽  
Diabetic Macular Edema ◽  
Density Lipoprotein ◽  
Creatinine Ratio ◽  
Albumin Creatinine Ratio ◽  
Urine Albumin ◽  
Urine Albumin Creatinine Ratio

Introduction: Diabetic Macular Edema is a diffuse thickening in macula which can be found in various severity of Diabetic Retinopathy. There are issue about relationship between Diabetic Macular Edema and albuminuria caused by chronic renal failure. The aim of this study is to know and compare urine albumin creatinine ratio among Diabetic Retinopathy patients with and without Diabetic Macular Edema in Moh. Hoesin Hospital. Methods: Cross sectional study with 25 sample was conducted. Diabetic Retinopathy and Diabetic Macular Edema was classified base on Early Treatment Of Diabetic Retinopathy Study (ETDRS) criteria. T-test, odd ratio and multiple logistic regretion analysis was used to analysed sociodemography characteristic (age and gender), clinical characteristic (duration of DM, hipertension, treatment, body mass indeks and antioksidan consumption), ophtalmology characteristic (visus, anterior segment anomaly and posterior segment/ severity of Diabetic Retinopathy), laboratory characteristic (HbA1c, ureum, creatinine, urine albumin creatinine ratio, and lipid profile). Result: Urine albumin creatinine ratio mean (2146.77 ± 3796.19) in Diabetic Macular Edema and (49.0 ± 45.35) in non-Diabetic Macular Edema; cutoff point 62.00 mg/dL. Odd ratio adjusted for urine albumin creatinine ratio = 18,8. In this research, risk factors which has significantly were urine albumin creatinine ratio (p=0.047) and High-Density Lipoprotein/HDL (p=0.028) with odd ratio 8.571 and 6.67 respectively. Urine albumin creatinine ratio showed significantly high Mann whitney analysis 0.02 (p<0.005). Conclusion: Urine albumin creatinine ratio in Diabetic Retinopathy with Diabetic Macular Edema was higher than without Diabetic Macular Edema. Urine albumin creatinine ratio and High Density Lipoprotein (HDL) are the two important risk factors associated with Diabetic Macular Edema.

scholarly journals Incident Chronic Kidney Disease Risk among Hispanics/Latinos in the United States: The Hispanic Community Health Study/Study of Latinos (HCHS/SOL)

2020 ◽  
Vol 31 (6) ◽  
pp. 1315-1324
Author(s):  
Ana C. Ricardo ◽  
Matthew Shane Loop ◽  
Franklyn Gonzalez ◽  
Claudia M. Lora ◽  
Jinsong Chen ◽  
...  
Keyword(s):  
United States ◽  
Risk Factors ◽  
The United States ◽  
Health Study ◽  
Creatinine Ratio ◽  
Albumin Creatinine Ratio ◽  
Urine Albumin ◽  
Hispanic Community ◽  
Urine Albumin Creatinine Ratio ◽  
Rate Ratios

BackgroundAlthough Hispanics/Latinos in the United States are often considered a single ethnic group, they represent a heterogenous mixture of ancestries who can self-identify as any race defined by the U.S. Census. They have higher ESKD incidence compared with non-Hispanics, but little is known about the CKD incidence in this population.MethodsWe examined rates and risk factors of new-onset CKD using data from 8774 adults in the Hispanic Community Health Study/Study of Latinos. Incident CKD was defined as eGFR <60 ml/min per 1.73 m2 with eGFR decline ≥1 ml/min per 1.73 m2 per year, or urine albumin/creatinine ratio ≥30 mg/g. Rates and incidence rate ratios were estimated using Poisson regression with robust variance while accounting for the study’s complex design.ResultsMean age was 40.3 years at baseline and 51.6% were women. In 5.9 years of follow-up, 648 participants developed CKD (10.6 per 1000 person-years). The age- and sex-adjusted incidence rates ranged from 6.6 (other Hispanic/mixed background) to 15.0 (Puerto Ricans) per 1000 person-years. Compared with Mexican background, Puerto Rican background was associated with 79% increased risk for incident CKD (incidence rate ratios, 1.79; 95% confidence interval, 1.33 to 2.40), which was accounted for by differences in sociodemographics, acculturation, and clinical characteristics. In multivariable regression analysis, predictors of incident CKD included BP >140/90 mm Hg, higher glycated hemoglobin, lower baseline eGFR, and higher baseline urine albumin/creatinine ratio.ConclusionsCKD incidence varies by Hispanic/Latino heritage and this disparity may be in part attributed to differences in sociodemographic characteristics. Culturally tailored public heath interventions focusing on the prevention and control of risk factors might ameliorate the CKD burden in this population.

scholarly journals Association of Microalbuminuria with Metabolic Syndrome among Aged Population

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Xiao-Hong Li ◽  
Hai-Yan Lin ◽  
Shu-Hua Wang ◽  
Li-Ying Guan ◽  
Yi-Bing Wang
Keyword(s):  
Metabolic Syndrome ◽  
Multivariate Regression ◽  
Density Lipoprotein ◽  
Creatinine Ratio ◽  
Albumin Creatinine Ratio ◽  
Aged Population ◽  
Urine Albumin ◽  
Predominant Component ◽  
Urine Albumin Creatinine Ratio ◽  
The Impact

Background. The impact of the various components of metabolic syndrome (MetS) on chronic kidney disease has been conflicting. We aim to investigate the association between MetS and microalbuminuria and identify the major contributing components of MetS that result in microalbuminuria in the Chinese aged population. Methods. A total of 674 adults aged 55–98 years (males: 266; mean age: 66.5±7.5 years) were studied. MetS was defined by the 2004 Chinese Diabetes Society criteria and microalbuminuria by urine albumin-creatinine ratio (UACR) ≥3 mg/mmoL. Results. The prevalence of microalbuminuria was gradually increased with increasing number of MetS components (P<0.05). In multivariate regression, after adjusting for age and sex, MetS was the strongest correlate of microalbuminuria (OR = 1.781, 95% CI = 1.226–2.587; P<0.05) followed by the fasting plasma glucose (FPG) (OR = 1.217, 95% CI = 1.044–1.092; P<0.05), systolic blood pressure (SBP) (OR = 1.011, 95% CI = 1.107–1.338; P<0.05), and high-density lipoprotein cholesterol (HDL-C) (OR = 0.576, 95% CI = 0.348–0.953; P<0.05). Conclusions. MetS is independently associated with microalbuminuria in the Chinese aged population. Elevated FPG is the most predominant component of metabolic syndrome associated with microalbuminuria followed by elevated SBP and reduced HDL-C.

scholarly journals Risk factors for development of nephropathy in patients with a diabetic Charcot foot

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Rasmus Bo Jansen ◽  
Per E. Holstein ◽  
Bo Jørgensen ◽  
Klaus Kirketerp Møller ◽  
Ole Lander Svendsen
Keyword(s):  
Risk Factors ◽  
Impaired Renal Function ◽  
Rare Complication ◽  
Total Duration ◽  
Foot Deformities ◽  
Creatinine Ratio ◽  
Charcot Foot ◽  
Albumin Creatinine Ratio ◽  
Urine Albumin ◽  
Urine Albumin Creatinine Ratio

Abstract Objective Charcot foot is a rare complication to neuropathy and can cause severe foot deformities and ulcerations, which often require prolonged antibiotical treatment. The objective of this retrospective study was to investigate whether this treatment is associated to impaired renal function. Results In total, 163 patients were included, of whom 105 (64%) had received β-lactam antibiotics for a mean total duration of 13.0 months. There was a significant increase in the urine albumin/creatinine ratio in the group that received antibiotics (p = 0.017), and the use of antibiotics was associated to a subsequent diagnosis of nephropathy (p = 0.01). Patients treated with antibiotics had a 21.9% risk of developing subsequent nephropathy versus 5.2% for patients not treated with antibiotics. We suggest increased awareness on signs of nephropathy in patients with severe Charcot foot.

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