scholarly journals STUDY OF LIPID AND THYROID PROFILE IN EARLY MENOPAUSAL WOMEN IN DR. B.R.AMBEDKAR MEDICAL COLLEGE AND HOSPITAL.

2021 ◽  
pp. 1-3
Author(s):  
Rekha G ◽  
Rajdeepak V S ◽  
Satish L
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Lipid Profile ◽  
Thyroid Dysfunction ◽  
Ischemic Heart ◽  
Medical College ◽  
Number Of Patients ◽  
Menopausal Women ◽  
Thyroid Profile

INTRODUCTION: Menopause is a normal, natural event, defined as the final menstrual period (FMP). Women now spend one third to one half of their lives after menopause. Women who underwent natural menopause before age 45 years had an increased risk of thyroid dysfunction, diabetes, hypertension, obesity and dyslipidemia which are considered as risk factors for ischemic heart disease. METHODOLOGY: 50 early menopausal women attending the outpatient and inpatient departments of DR.B.R. Ambedkar Medical College and Hospital, were randomly included in this study. All the patients are subjected to detailed history regarding demographic data, general physical examination (including vitals, weight, height, BMI). Investigations like Thyroid profile (T3,T4,TSH), Fasting Lipid Profile, ECG were done. RESULTS: Study patients were found to be in 40-70 years age group, with maximum number of patients in 40-50 years group. Mean age of menopause is 42.34±1.92. Among the studied population 27(54%) patients had thyroid dysfunction. All 27 patients had hypothyroidism, 3(13%) patients had subclinical hypothyroidism upon evaluation and rest of the patients were euthyroid. TSH was found to be higher 6.50±4.87 among the studied patients and was found to be statistically associated with thyroid disorders. In studied subjects 19(38%) had dyslipidemia, 1 patient had borderline and rest 30 patients had normal lipid profile. 17(34%) of studied patients had ischemic heart disease. Among the 17 patients having IHD, 10(58.82%) patients were hypothyroid, 15(88.23%) patients had hypertension and 10 (52.63%) had dyslipidemia. Amongst the studied subjects 33(66%) patients were overweight and 9(18%) patients were obese according to BMI. CONCLUSION: Significant number of early menopausal women in this study have hypertension, thyroid dysfunction, dyslipidemia and high BMI which are considered as risk factors for coronary artery disease. Hence screening can be recommended for early menopausal women for thyroid dysfunction, especially in those with increasing age , duration of menopause and overweight women to evaluate and correct dyslipidemia so as to prevent adverse atherosclerotic cardiovascular complications and to prevent morbidity and mortality.

scholarly journals Serum Lipid Profile in Ischemic Heart Disease: A Cross-Sectional Analytical Study

2014 ◽  
Vol 7 (1) ◽  
pp. 14-16 ◽  
Author(s):  
BA Ferdous ◽  
N Sultana ◽  
S Ahmed ◽  
EH Khan ◽  
S Sultana ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ischaemic Heart Disease ◽  
Analytical Study ◽  
Ischemic Heart ◽  
Cholesterol Concentration ◽  
Cross Sectional ◽  
Medical College

Risk of coronary heart disease and other forms of atherosclerotic vascular diseases, rises with plasma cholesterol concentration and in particular with the rise of ratio of total cholesterol to high density lipoprotein (HDL-C) cholesterol. A much weaker correlation also exists with plasma triglyceride concentration. Extensive large-scale randomized trials have shown that lowering total cholesterol and LDL-C concentrations reduces the risk of cardiovascular events including death, myocardial infarction and stroke and reduces the need for revascularisation.This cross-sectional analytical study was designed to observe association between lipid profile level with chronic ischaemic heart disease and the study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from July 2010 to June 2011. A total of 50 cases were selected purposively according to the selection criteria from the patients admitted in the Department of Cardiology, Dhaka Medical College Hospital with chronic ischaemic heart disease (IHD). Diagnosed IHD patients were taken as cases and 50 age- & sex- matched healthy subjects were taken as controls. Serum TC, TG, LDL-C & HDL-C were measured in all study subjects.The mean±SD of serum TC, TG, HDL-C and LDL-C concentration in cases were 314.54±73.72 mg/dl, 288.04±60.45 mg/dl, 36.02±4.12 mg/dl, and 178.62±22.7 mg/dl respectively and in controls were 174.64±18.97 mg/dl, 119.42±12.47 mg/dl, 43.04±2.58 mg/dl & 126.28±11.45 mg/dl respectively. Serum Total Cholesterol, TG & LDL-C were found to be significantly higher in cases than that of controls. Serum HDL-C was found to be significantly lower in cases than that of controls. The present study reveals that the patients with chronic ischemic heart disease is accociated with significantly higher levels of serum TC, TG and LDL-C whereas HDL-C was found to be lower in IHD patients. DOI: http://dx.doi.org/10.3329/bjmb.v7i1.18574 Bangladesh J Med Biochem 2014; 7(1): 14-16

IMPACT OF RISK FACTORS OF ISCHEMIC HEART DISEASE ON THE DEVELOPMENT OF ACUTE CORONARY SYNDROME, PLATELET ULTRASTRUCTURE, AND ASPIRIN RESISTANCE

2019 ◽  
Vol 72 (11) ◽  
Author(s):  
Yulian H. Kyyak ◽  
Olga Yu. Barnett ◽  
Marta P. Halkevych ◽  
Olha Ye. Labinska ◽  
Hryhoriy Yu. Kyyak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Aspirin Resistance ◽  
Ischemic Heart ◽  
Coronary Syndrome

IMPACT OF RISK FACTORS OF ISCHEMIC HEART DISEASE ON THE DEVELOPMENT OF ACUTE CORONARY SYNDROME, PLATELET ULTRASTRUCTURE, AND ASPIRIN RESISTANCE

2019 ◽  
Vol 72 (11) ◽  
Author(s):  
Yulian H. Kyyak ◽  
Olga Yu. Barnett ◽  
Marta P. Halkevych ◽  
Olha Ye. Labinska ◽  
Hryhoriy Yu. Kyyak ◽  
...  
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Aspirin Resistance ◽  
Ischemic Heart ◽  
Coronary Syndrome

Gender difference in risk factors associated with ischemic heart disease in Lahore

2020 ◽  
Vol 14 (2) ◽  
pp. 72-77
Author(s):  
Muhammad Salman Tariq ◽  
Iram Manzoor ◽  
Qurat Ul Ain Zulfi ◽  
Naeem Hussain ◽  
Nimra Saleem ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Disease ◽  
Gender Difference ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Public Health Issue ◽  
Stressful Event ◽  
Female Population ◽  
High Tendency ◽  
Factors Associated

Background: Ischemic heart disease (IHD) is one of the leading causes of mortality in Pakistan. With advancement in research, multiple causes have contributed in development of web of causation of this public health issue. The objective of this study was to assess gender differences in risk factors associated with ischemic heart disease in patients presenting at the biggest cardiology hospital of Lahore. Patients and methods: A comparative cross-sectional study was carried out in Punjab Institute of Cardiology, Lahore from January to August, 2018 on a sample of 296 diagnosed patients of IHD, through non-probability consecutive sampling technique. Data was collected on pretested questionnaire. The data was analyzed using SPSS version 22. Chi-Square test of significance was applied and a p-value ≤0.05 was considered statistically significant. Results: The mean age of participants was 45±12 years with predominance of male patients (71.3%). Frequency of risk factors for IHD included increase body mass index (83.8%), hypertension (61%), insufficient physical activity (43%), diabetes (38.5%) and smoking (23%). Increase serum cholesterol was reported in 95% and triglycerides in 99% of the participants. Gender difference was significant with females residing in urban population (p=0.054) and exercise routine (p=0.034). Males showed high tendency of IHD with smoking pattern (p<0.001) contrary to presence of diabetes in females (p=0.05), hypertension (p=0.054), BMI (p=0.0379) and stressful event in life (p=0.002). Males showed regular intake of medicines (p =0.045) after diagnosis as compared to female population. Conclusion: There is more frequency of ischemic heart disease in males as compared to females. Significant association was observed with residence in urban area, presence of diabetes, hypertension, high BMI and stressful event in life in occurrence of ischemic heart disease in female population.

Sign in / Sign up

Export Citation Format

Share Document