A PROSPECTIVE STUDY OF MATERNALAND FETAL OUTCOME IN PREECLAMPSIAAND ECLAMPSIA

Mapping Intimacies ◽

10.36106/ijsr/3502288 ◽

2021 ◽

pp. 60-61

Author(s):

Naveed Tamboli ◽

Hemant Murdeshwar ◽

Gulafroz SK Samad

Keyword(s):

Prospective Study ◽

Fetal Outcome ◽

Maternal Outcome ◽

Severe Preeclampsia ◽

Morbidity And Mortality ◽

Haematological Parameters ◽

Coagulation Status ◽

Mild Preeclampsia ◽

A Prospective Study

Introduction- Pre eclampsia and eclampsia is one of the leading cause of maternal and fetal morbidity and mortality. This study was undertaken to correlate coagulation prole in patients with pre-eclampsia and eclampsia with maternal and fetal outcome. Materials And Methods- A prospective study was conducted on 164 cases and 70 controls over a period of 2 years. The coagulation prole was carried out on the semiautomated TRINITY coagulometer. The haematological parameters were assessed on fully automated 3 part haematological analyser- TRIVITRON Model-CELLENIUM-19. The patients were classied into mild preeclamptic, severe preeclamptic and eclamptic based on the clinical and haematological parameters. Observations- The maternal and the foetal outcomes were studied and correlated with the coagulation prole. All the cases of mild preeclampsia had favourable maternal and fetal outcome. Out of total 102 cases of severe preeclampsia and eclampsia, 78 had normal coagulation prole and 24 had deranged prole. Thus out of 24 patients with deranged coagulation prole, 21 (87.5%) women had adverse maternal outcome and 24 (100%) had unfavourable fetal outcome. Conclusion- Deranged coagulation prole in preeclampsia and eclampsia is signicantly associated with adverse maternal and fetal outcome. Thus suspecting a deranged coagulation status early in the course of the disease will guide us in management before the patient goes into complications.

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A prospective study of 20 cases of maternal outcome in morbidly adherent placenta in tertiary care hospital

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20170384 ◽

2017 ◽

Vol 6 (2) ◽

pp. 571

Author(s):

Krishna Vora ◽

Pallavi Chandana ◽

Amrita Patel ◽

Mahima Jain

Keyword(s):

Prospective Study ◽

Maternal Outcome ◽

Placenta Praevia ◽

Morbidity And Mortality ◽

High Morbidity ◽

Care Hospital ◽

Morbidly Adherent Placenta ◽

Adherent Placenta ◽

One Year ◽

A Prospective Study

Background: Morbidly adherent placenta with its variants is one of the most feared complication causing high morbidity and mortality in obstetrics. Aim of this study is to help in identifying high risk pregnancies, planning line of management of morbidly adherent placenta. The objective of the study wad to evaluate the risk factors, different modes of management, maternal outcome in case of morbidly adherent placenta.Methods: A prospective study for one year was done to describe the incidence, causes, treatment, complications, and maternal morbidity and mortality associated with morbidly adherent placenta.Results: A total of 20 cases of morbidly adherent placenta were studied over one-year span at our Institute. Most of the women with morbidly adherent placenta were in the age group of 26-30years (55%).The most common aetiology of morbidly adherent placenta was previous caesarean scar with placenta praevia (85%). In majority, placenta accreta found. Total abdominal hysterectomy done in 12 patient and subtotal hysterectomy in 6 cases. Trial haemostasis with uterine sparing in 2 cases out of which one case underwent total hysterectomy due to massive haemorrhage on same day. Associated Bladder repair in adherent placenta with invasion of bladder was needed in 10% cases. There was 1 maternal death noted in this study.Conclusions: Leading cause of morbidly adherent placenta is previous caesarean section with placenta praevia, high index of suspicion, early antenatal diagnosis, planned surgery at high care centre with multi-disciplinary expertise, anticipation of blood volume transfusion, Delivery of foetus without manipulating placenta are key steps to reduce morbidity and mortality in morbidly adherent placenta. The decision to perform hysterectomy and conservative management to be individualized. Timely decision is the key to get success in morbidly adherent placenta as in other obstetric emergencies.

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Hubungan antara Soluble Fms-Like Tyrosine Kinase-1 (sFlt-1) pada Ibu Preeklampsia Berat dengan fetal outcome

Jurnal Endurance ◽

10.22216/jen.v5i1.4668 ◽

2020 ◽

Vol 5 (1) ◽

pp. 126

Author(s):

Mona Dewi Utari ◽

Fenny Fenny ◽

Andina Andina ◽

Ria Ria

Keyword(s):

Body Weight ◽

Tyrosine Kinase ◽

Health Workers ◽

Fetal Outcome ◽

Severe Preeclampsia ◽

Morbidity And Mortality ◽

Cross Sectional ◽

New Born ◽

Consecutive Sampling ◽

Regulatory Failure

Preeclampsia is a major source of maternal morbidity and mortality throughout the world including Indonesia. Regulatory failure and imbalance of proangiogenic and anti angiogenic placental vasoactive agents such as soluble fms-like tyrosine kinase-1 (sFlt-1) proven to play an important role in the pathogenesis of preeclampsia. Preeclampsia is very dangerous because otherwise it can cause morbidity and mortality in the mother also gives a very bad effect for the fetus. The purpose of this study was to determine correlate sflt-1 in severe preeclampsia with fetal outcome. This research is an observational study with research desain cross-sectional. The sample of this study was maternity who were diagnosed with severe preeclampsia as many as 27 sample by consecutive sampling. sFlt-1 levels were examined by ELISA. The result showed there is correlate sFlt-1 with new born body weight (Pvalue=0,01), there is no correlate between sFlt-1 and score apgar (Pvalue=0,91), there is no correlate between sFlt-1 and stillborn (Pvalue=0,84). The conclution of this study there is correlate sFlt-1 with new born body weight. Health workers are expected to be able to reduce the risk of severe preeclampsia / eclampsia as early as possible starting from the physical and mental preparation of each expectant mother especially nutrition and stressing the importance of regular and periodic antenatal visits. Preeklampsia merupakan sumber utama morbiditas dan mortalitas ibu di seluruh dunia termasuk Indonesia. Kegagalan pengaturan dan ketidakseimbangan agen vasoaktif proangiogenik dan anti angiogenik plasenta seperti soluble fms-like tyrosine kinase-1(sFlt-1) terbukti memainkan peranan penting dalam patogenesis preeclampsia. Preeklampsia sangat berbahaya karena selain dapat menyebabkan morbiditas dan mortalitas pada ibu juga memberikan efek yang sangat buruk bagi janin. Tujuan Penelitian ini adalah untuk mengetahui hubungan antara sFlt-1 pada ibu preeklampsia berat dengan fetal outcome. Penelitian ini merupakan penelitian observasional dengan desain penelitian cross-sectional. Sampel penelitian ini adalah ibu bersalin yang terdiagnosa Preeklampsia Berat sebanyak 27 orang dengan cara consecutive sampling. Kadar sFlt-1 diperiksa dengan ELISA. Hasil penelitian menunjukkan bahwa terdapat hubungan antara sFlt-1 dengan berat badan bayi baru lahir dengan nilai p=0,01, tidak terdapat hubungan antara sFlt-1 dengan APGAR Score dengan nilai p=0,91, tidak terdapat hubungan antara sFlt-1 dengan lahir mati dengan nilai p=0,84. Kesimpulan hasil penelitian diketahui terdapat hubungan kadar sFlt-1 pada ibu preeklampsia berat dengan Berat badan bayi baru lahir. Petugas kesehatan diharapkan mampu mengurangi resiko terjadinya preeklampsia berat/eklampsia sedini mungkin dimulai dari persiapan fisik dan mental pada setiap calon ibu terutama nutrisi dan menekankan pentingnya kunjungan antenatal yang teratur dan berkala.

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269 A prospective study of factors predicting morbidity and mortality in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for advanced epithelial ovarian malignancy

10.1136/ijgc-2019-igcs.269 ◽

2019 ◽

Author(s):

VK Ahuja ◽

S Somashekar ◽

K Ashwin ◽

S Zaveri ◽

C Rohit Kumar ◽

...

Keyword(s):

Prospective Study ◽

Intraperitoneal Chemotherapy ◽

Cytoreductive Surgery ◽

Hyperthermic Intraperitoneal Chemotherapy ◽

Morbidity And Mortality ◽

Ovarian Malignancy ◽

A Prospective Study

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Sick leave due to mental disorders, morbidity and mortality: a prospective study of discordant twin pairs

Social Psychiatry and Psychiatric Epidemiology ◽

10.1007/s00127-019-01715-9 ◽

2019 ◽

Vol 55 (1) ◽

pp. 25-32

Author(s):

Lisa Mather ◽

J. Narusyte ◽

A. Ropponen ◽

G. Bergström ◽

V. Blom ◽

...

Keyword(s):

Mental Disorders ◽

Sick Leave ◽

Prospective Study ◽

Morbidity And Mortality ◽

A Prospective Study ◽

Discordant Twin

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Long-term effect of levetiracetam monotherapy on haematological parameters in children with epilepsy: A prospective study

Epilepsy Research ◽

10.1016/j.eplepsyres.2018.07.001 ◽

2018 ◽

Vol 145 ◽

pp. 160-162 ◽

Cited By ~ 3

Author(s):

Achilleas Attilakos ◽

Argirios Dinopoulos ◽

Maria Paschalidou ◽

Maria Tsirouda ◽

Maria Karalexi ◽

...

Keyword(s):

Prospective Study ◽

Term Effect ◽

Haematological Parameters ◽

Long Term Effect ◽

A Prospective Study

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Study of sociodemographic profile, maternal, fetal outcome in preeclamptic and eclamptic women: a prospective study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20196025 ◽

2019 ◽

Vol 9 (1) ◽

pp. 230

Author(s):

Vedavathi . ◽

Rajeev Sood

Keyword(s):

Blood Pressure ◽

Prospective Study ◽

Systolic Blood Pressure ◽

Diastolic Blood Pressure ◽

Perinatal Outcomes ◽

Neonatal Morbidity ◽

Fetal Outcome ◽

Morbidity And Mortality ◽

Intrauterine Death ◽

Perinatal Morbidity

Background: Preeclampsia is pregnancy specific disease, lead to maternal, perinatal morbidity and mortality. This study is conducted to identify the socio demographic profile of subjects suffering from preeclampsia and its effect on maternal and fetal health.Methods: This prospective study was conducted at department of obstetrics and gynecology, Kamla Nehru State Hospital, Shimla, in this, 100 preeclamptic women were included. Preeclampsia was diagnosed with blood pressure of ≥140/90 mmHg noted for the first-time during pregnancy, after 20 wks of gestation and proteinuria. Demographic details were collected. Investigations i.e. hemogram, liver and renal function tests, coagulation profile and fundoscopy were done. Maternal and perinatal outcomes were recorded.Results: In this study, majority of the subjects were primigravida 65. In this, 11 subjects had systolic blood pressure of 140-159 mmHg and 89 subjects had systolic blood pressure of > 160 mmHg. 25 subjects had diastolic blood pressure of 90-109 mmHg and 75 subjects had diastolic blood pressure of > 110 mmHg. In this, 82 subjects had warning symptoms, mainly headache 49. 14 subjects showed hypertensive changes in fundus. Unfavorable Bishop Score, observed in 86 subjects and 78 subjects were induced after controlling blood pressure. Majority of subjects had vaginal delivery 73. Majority of the subjects had deranged liver function 61. Maternal morbidity was reported in 54 subjects. Intrauterine death reported in 14 subjects. Birth weight was < 2.5 kg was observed in 70 babies. Out of 74 live births, 53 neonates required admission in NICU and 16 neonates died in NICU.Conclusions: It may be concluded that, maternal and neonatal morbidity and mortality can be reduced by early identification of risk factors and timely intervention is the hall mark in preventing the maternal and perinatal morbidity and mortality.

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