FACTORS ASSOCIATED WITH THE OUTCOME OF ATT AMONG HIV-TB COINFECTED PATIENTS ATTENDING THE ART CENTRE OF A TERTIARY CARE HOSPITAL OF JHARKHAND: A PROSPECTIVE HOSPITAL BASED STUDY

2021 ◽  
pp. 3-4
Author(s):  
Abhishek Kumar ◽  
Mithilesh Kumar ◽  
Vivek Kashyap

Background: Despite being preventable and curable, TB is the leading cause of HIV associated mortality. It is the most common opportunistic 3 infection among HIV positive individuals with CD4 cell count < 500/mm . Worldwide the number of people infected with both HIV& TB is rising. Objectives: To assess the treatment outcome of HIV-TB Co-infected patients on Anti Tubercular treatment (ATT) attending ART Centre, RIMS, Ranchi. Methods: It was a hospital based prospective study done at the ART centre of Rajendra Institute of Medical Sciences (RIMS), Ranchi. Duration of study was 14 months. Atotal of 117 patients were registered during the study period and were followed up for outcome of ATT. Results: Out of 117 patients 4 were excluded and from remaining 113 patients, treatment success was found to be 88.5%. No signicant association was found among any of the socio-demographic variables and outcome of TB treatment. Conclusion: In this study it was concluded that sociodemographic prole had no signicant association (p>0.05) with the outcome of TB treatment and treatment success (Cured & Treatment completed) was found in 88.5% of the HIV-TB co-infected patients

Author(s):  
Abhishek Kumar ◽  
Vivek Kashyap

Background: Despite being preventable and curable, TB is the leading cause of HIV associated mortality. It is the most common opportunistic infection among HIV positive individuals with CD4 cell count <500/ mm3. Worldwide the number of people infected with both HIV & TB is rising. The objective of the study was to describe the socio-demographic profile of HIV-TB co-infected patients and to assess the adherence of HIV TB Co-infected patients to anti tubercular treatment (ATT) attending ART Centre, RIMS, Ranchi.Methods: It was a hospital based prospective study done at Rajendra Institute of Medical Sciences (RIMS), Ranchi. Duration of study was 14 months. A total of 117 patients were registered during the study period and were followed up for adherence to ATT.Results: Out of 117 patients 4 were excluded. Among 113 patients, mostly were male (74.3%) and from rural background (69.9%). Majority (94.7%) of the patients came for regular follow up and took medicines as advised. Adherence was significantly associated with education (p=0.025).Conclusions: In this study it was concluded that education significantly affected adherence to ATT among HIV-TB Co-infected patients of ART Centre of RIMS, Ranchi.


2020 ◽  
Vol 31 (7) ◽  
pp. 705-707
Author(s):  
Venkateshwaran Sivaraj ◽  
Rudiger Pittrof ◽  
Olubanke Davies ◽  
Ranjababu Kulasegaram

A cohort review was conducted at a central London tertiary care hospital trust on the prevalence of homelessness among human immunodeficiency virus (HIV)-positive inpatients over a year. Data were collected on the duration of inpatient stay, co-morbidities including acquired immune deficiency syndrome (AIDS)-defining illnesses, co-infections, initiation of antiretroviral therapy, CD4 cell count, HIV viral load and substance misuse. Homeless people were found to be at high risk for hepatitis C, mental health illness, substance misuse including injecting drug use, recurrent bacterial infections, AIDS-associated illnesses, lower CD4 cell counts and HIV viremia. They also had more missed HIV outpatient appointments. It was highlighted that a multidisciplinary approach in their care was necessary to address their needs and reduce the morbidity burden in this cohort.


2016 ◽  
Vol 62 (2) ◽  
pp. 285-288
Author(s):  
Raluca Jipa ◽  
Oana Săndulescu ◽  
Eliza Manea ◽  
Şerban Benea ◽  
Otilia Benea ◽  
...  

AbstractObjective: The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS).Methods: We retrospectively studied data on HIV-infected patients hospitalized in one tertiary care hospital in Bucharest, Romania, in whom Kaposi Sarcoma was diagnosed, between January 2008 and November 2013.Results: We identified 27 HIV-infected patients diagnosed with KS within 6 years. They had a median age of 42 years old and a median CD4 cell count of 101 cells per mm3 at the time of KS diagnosis. All patients received antiretroviral therapy (ART), with 18 patients (66%) already on ART at the time of KS diagnosis. Most patients (59%) were classified as ACTG poor-risk and 56% as Mitsuyasu stage I. The overall prognosis was poor, with 41% mortality, in a median time span of 6 months, significantly correlated with gastrointestinal involvement (p=0.019), poor-risk KS in ACTG classification (p<0.001) and stage IV Mitsuyasu (p=0.006).Conclusion: KS remains an important cause of morbidity and mortality in patients with HIV infection, especially in late presenters.


2017 ◽  
Vol 01 (04) ◽  
pp. 127-132
Author(s):  
Bhushan Shrikhande ◽  
Meena Mishra ◽  
Mohiuddin Qazi ◽  
Arvind Kurhade ◽  
Chandrashekhar Unakal ◽  
...  

2014 ◽  
Vol 6 (3) ◽  
pp. 159-162
Author(s):  
Dhrubajyoti Sarkar ◽  
Banasree Bhadra ◽  
Suvobrata Sarkar ◽  
Biswajit Chakraborty

ABSTRACT Objective To know the prevalence of human immunodeficiency virus (HIV) among antenatal mothers. Materials and methods It is a retrospective study of antenatal mothers attending the integrated counseling and testing centre (ICTC), College of Medicine and JNM Hospital, Kalyani, from January 2009 to December 2013. Antenatal mothers were counseled and in those willing to undergo test rapid testing was done. First time positive cases were retested two more times by two different companies rapid test kit. The samples were considered as positive when found reactive by all three different methods. Results In our study, a total number of 11343 new antenatal mothers were registered. The pretest counseling could be done for 9437 antenatal mothers. After counseling, testing could be done in 9211 antenatal mothers. In our 5 years study period, a total of six cases were HIV positive. Out of these HIV positive cases, three were in 2009, no case was detected in 2010, one was in 2011, one in 2012 and one in 2013. Thus, the incidence of HIV (in tested mothers) is 0.13% in 2009, 0 in 2010, 0.06% in 2011, 0.07% in 2012 and 0.05% in 2013. Overall incidence was 0.065%. Conclusion There is a declining trend of HIV prevalence among antenatal mothers reflecting that prevention campaigns are working effectively. How to cite this article Bhadra B , S arkar D , S arkar S ,Chakraborty B. Prevalence of Human Immunodeficiency Virus in Antenatal Mothers in a Rural Tertiary Care Hospital. J South Asian Feder Obst Gynae 2014;6(3):159-162.


2019 ◽  
Vol 30 (2) ◽  
pp. 163-171
Author(s):  
Amod Tilak ◽  
Smita Shenoy ◽  
Muralidhar Varma ◽  
Asha Kamath ◽  
Amruta Tripathy ◽  
...  

AbstractIntroductionThere is a dearth of studies assessing the efficacy and immunological improvement in patients started on antiretroviral therapy (ART) in India. This study was undertaken to assess the 2-year treatment outcomes in HIV-positive patients initiated on ART in a tertiary-care hospital.MethodsAfter approval from the Institutional Ethics Committee, adult HIV-positive patients from a tertiary-care hospital, initiated on ART between January 2013 and February 2015, were included in the study. Data on clinical and immunological parameters were obtained from medical case records over a period of 2 years after initiation of therapy. Intention-to-treat analysis was done using a descriptive approach, using SPSS version 15 (SPSS Inc. Released 2006. SPSS for Windows, Version 15.0. Chicago, SPSS Inc.). A logistic regression analysis was done to assess the predictors for poor outcomes. A p-value <0.05 was considered statistically significant.ResultsART was initiated in 299 adult patients. At 1 and 2 years, the median (interquartile range) change in CD4+cell count was 65 (39, 98) cells/mm3and 160 (95, 245) cells/mm3. The change observed after 2 years of treatment initiation was statistically significant compared with that after 1 year. Three deaths occurred during the study period and 28 were lost to follow-up. Male sex, presence of at least one opportunistic infection at the start of therapy, and baseline CD4+count <50 cells/mm3were associated with poor immunological recovery.ConclusionsWith long-term treatment and regular follow-up, sustained clinical and immunological outcomes can be obtained in resource-limited settings.


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