STUDY OF DRUG UTILIZATION PATTERNS IN POSTPARTUM WOMEN IN GOVERNMENT MEDICAL COLLEGE, JAMMU (INDIA).

Background: There is a paucity of literature regarding rational prescribing practices especially during postnatal period.It was found worthwhile to assess the drug utilization patterns during postpartum period.It is known fact that the drugs prescribed during postnatal period have significant impact on the health of both mother and child. Material and Methods:A total of 1300 prescriptions of the patients which include 552 caesarian sections (cs) and 748 pervaginal (pv) delivery were randomly selected and studied. Results:It was recorded that the average number of drugs prescribed per prescription were 6.01 in cs patients and 10.95 in pv delivery group.The most commonly drugs that were prescribed were Antibiotics, analgesics, anti-inflammatory drugs, nutritional supplements (iron, calcium, multivitamins), H2 blockers and proton pump inhibitors (PPIs).In addition the other drugs included were oxytocin,prostaglandins,uetrine relaxants,antihyperttensives,bronchodilators,benzodiazepines,antifungal agents and antiepileptics.It was also found that 36.88%,16.75%,80.71% and 6.33% drugs prescribed were fixed dose combinations,generics,essential drugs and off label respectively in cs patients.Whereas, 42.96%, 13.23%, 78.81% and 8.2% drugs prescribed were fixed dose combinations, generic, essential drugs and off label respectively in pv patients. Conclusion: The results of this study reveals that there is need for educating prescribers regarding rational prescribing practices, especially during postnatal period when health of both infant and mother is at stake.

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Drug utilization pattern of analgesics as a teaching tool for rational therapy to MBBS students in a medical college at Dehradun, Uttarakhand, India

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20171089 ◽

2017 ◽

Vol 6 (4) ◽

pp. 842

Author(s):

Mirza Atif Beg ◽

Shakti B. Dutta ◽

Shalu Bawa ◽

Amanjot Kaur ◽

Subhash Vishal ◽

...

Keyword(s):

Drug Utilization ◽

Medical Curriculum ◽

Essential Medicine ◽

Fixed Dose ◽

Prescribing Practices ◽

Prescribing Pattern ◽

Medical College ◽

Drug Utilization Studies ◽

Rational Therapy ◽

Drug Utilization Research

Background: As a need to introduce Clinical Pharmacology at the undergraduate level the drug utilization studies (DUS) offer useful methods for teaching and training in drug therapy. The indiscriminate use of medicines results in unwanted side effects, drug interactions. Thus keeping this view in mind, this drug utilization research was set to evaluate the prescribing pattern of analgesics to impart certain basic skills to MBBS students which will form an integral component of practicing rational therapeutics.Methods: The retrospective study was conducted by Pharmacology department in SGRRIM and HS. A total of 726 prescriptions were collected by 2nd professional MBBS students entering 5th semester and randomly evaluated for prescribing pattern using WHO drug use indicators.Results: A total of 726 prescriptions were analyzed. Male:Female ratio was 470:256(1.8:1). Age wise distribution of patients 0-15years 122(16.80%), 16-30 years 139(19.41%), 31-45years 242 (33.33%), 46-60 years 113(15.56%) and >60years 110 (15.15%). A total of 4663 drugs were prescribed. 435(9.32%) were analgesics. 208 (47.81%) Paracetamol, 66 (15.17%) Tramadol, 62(14.25%) Aceclofenac, 51 (11.72%) Diclofenac, 46 (10.57%) Ibuprofen and 2(0.45%) Buprenorphine were prescribed. 301 (69.20%) Oral drugs and 134 (30.80%) Injectable were prescribed. 108 (24.83%) Numbers of Fixed dose combinations. 0.60 of analgesics were prescribed per prescription. 381 (87.59%) analgesics were prescribed from National Essential Medicine list 2015. 369 (84.83%) drugs were prescribed by brand names.Conclusions: The main purpose of undergraduate medical curriculum is to develop the requisite diagnostic and therapeutic skills of a basic doctor. Such type of drug utilization studies is set with the objective to encourage rational prescribing, and to identify good and bad prescribing practices.

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Review of Drug Utilization Studies in Neonatal Units: A Global Perspective

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17165669 ◽

2020 ◽

Vol 17 (16) ◽

pp. 5669 ◽

Cited By ~ 1

Author(s):

Asma Al-Turkait ◽

Lisa Szatkowski ◽

Imti Choonara ◽

Shalini Ojha

Keyword(s):

Drug Use ◽

Drug Utilization ◽

Antibiotic Use ◽

Global Perspective ◽

Use Patterns ◽

Rational Prescribing ◽

Drug Use Patterns ◽

General Drug ◽

The Usa ◽

Drug Utilization Studies

Rational prescribing is challenging in neonatology. Drug utilization studies help identify and define the problem. We performed a review of the literature on drug use in neonatal units and describe global variations. We searched databases (EMBASE, CINAHL and Medline) from inception to July 2020, screened studies and extracted relevant data (two reviewers). The search revealed 573 studies of which 84 were included. India (n = 14) and the USA (n = 13) reported the most. Data collection was prospective (n = 56) and retrospective (n = 26), mostly (n = 52) from one center only. Sixty studies described general drug use in 34 to 450,386 infants (median (IQR) 190 (91–767)) over a median (IQR) of 6 (3–18) months. Of the participants, 20–87% were preterm. The mean number of drugs per infant (range 11.1 to 1.7, pooled mean (SD) 4 (2.4)) was high with some reporting very high burden (≥30 drugs per infant in 8 studies). This was not associated with the proportion of preterm infants included. Antibiotics were the most frequently used drug. Drug use patterns were generally uniform with some variation in antibiotic use and more use of phenobarbitone in Asia. This study provides a global perspective on drug utilization in neonates and highlights the need for better quality information to assess rational prescribing.

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PHP20 PSYCHOTROPIC DRUG UTILIZATION PATTERNS AMONG ELDERLY NURSING HOME RESIDENTS IN THE UNITED STATES

Value in Health ◽

10.1016/s1098-3015(10)72401-3 ◽

2010 ◽

Vol 13 (3) ◽

pp. A85

Author(s):

S Bhattacharjee ◽

SU Karkare ◽

P Kamble ◽

R Aparasu

Keyword(s):

United States ◽

Nursing Home ◽

Drug Utilization ◽

Psychotropic Drug ◽

Nursing Home Residents ◽

The United States ◽

Utilization Patterns

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A nationwide evaluation of off-label drug utilization in Turkey

TURKISH JOURNAL OF MEDICAL SCIENCES ◽

10.3906/sag-1609-129 ◽

2017 ◽

Vol 47 ◽

pp. 1229-1238

Author(s):

Emine Nur ÖZDAMAR ◽

Ahmet AKICI ◽

Ali ALKAN ◽

Banu BAYAR ◽

Hakkı GÜRSÖZ

Keyword(s):

Drug Utilization ◽

Off Label

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Drug utilization pattern of antimicrobials in intensive care unit of a tertiary care teaching hospital

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20204103 ◽

2020 ◽

Vol 9 (10) ◽

pp. 1594

Author(s):

Saswat Satapathy ◽

Yajnesh P. Sahu ◽

Ashok K. Panigrahi ◽

Bhabagrahi Rath ◽

Ananta N. Patra

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Drug Utilization ◽

Drug Prescription ◽

Tertiary Care ◽

Quality Of Healthcare ◽

Cross Sectional Study ◽

Utilization Pattern ◽

Prescribing Practices ◽

Cross Sectional

Background: The intensive care unit is a setting where the multiple medications are prescribed to patients. Antimicrobials are heavily prescribed in the ICUs, which in turn enhance the risk of antimicrobial resistance, increase the side effects and increases the cost of treatment. Drug utilization study is a component of medical auditing that aims to monitor and evaluate the drug prescription patterns and to suggest necessary modifications in the prescribing practices to achieve rational therapeutic practice.Methods: A cross-sectional study was conducted in which data of patients admitted to ICU during the period from June 2019 to August 2019 was collected from the Medical Record Section of the hospital. Drug utilization pattern of antimicrobials in ICU was analyzed.Results: Out of 90 patients, 60 were males and 30 were females. The average duration of stay in ICU was 7.53 days. The most common antibiotic prescribed was ceftriaxone followed by piperacillin and tazobactam with DDD/100 bed days of 24.2 and 17.3 respectively.Conclusions: In this study, the results appeared to be similar to those reported in previous studies. However, prescription protocols need to be addressed to guide appropriate use of antimicrobials in the ICU setting. Therefore, it is necessary to conduct drug utilization research to understand the drug consumption and for implementation of protocols to improve the quality of healthcare.

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Prescribing patterns of cardiovascular drugs in cardiology outpatient department in a tertiary care hospital in Western Odisha

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20205533 ◽

2020 ◽

Vol 10 (1) ◽

pp. 23

Author(s):

Ayan Roy ◽

Nayan Kumar Patel

Keyword(s):

Drug Utilization ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Cardiovascular Drugs ◽

Prescribing Patterns ◽

World Health ◽

Fixed Dose ◽

Care Hospital ◽

Clinical Practices ◽

Common Diagnosis

Background: Cardiovascular morbidity plays a villainous role globally as well as countries like India. Additionally, irrational prescription incurs greater damage to health and wellbeing. Drug utilization studies scrutinize the appropriateness of treatment and provide favorable feedbacks to strengthen clinical practices. The objective of the study was to describe treatment practices in cardiology outpatient and drug utilization pattern using core prescribing indicators by World Health Organization (WHO).Methods: A cross-sectional, observational study of 4-month duration was undertaken for cardiology Outdoor patients at a tertiary care hospital. 615 prescriptions were screened and analyzed.Results: Males (59.84%) were more in number than females (40.16%). Average number of the prescribed drugs per patient were 4.32±2.7 and (3.73±1.1 for cardiovascular drugs). Generic prescription was 60.98%. Percentage encounters with antibiotics 4.11, injectables 2.92%, fixed-dose combinations (FDCs) (11.8%) were documented. Drugs from the National List of Essential Medicines were 75.89%. The most common diagnosis was ischemic heart disease (68.29%). Hypolipidemics (78.25%) followed by antiplatelets (71.14%) were toppers in cardiovascular drug. Antiulcer drugs (PPI/Antacids) comprised 58.54% of total prescriptions.Conclusions: Less adherence to EDL, less generic prescriptions, use of FDC are major shortcomings. Areas to further rationalization like optimal use of evidence based medication like beta-blockers, newer anticoagulants/anti-platelet agents and newer anti-anginal agents are identified.

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Drug utilization audit of antipsychotics using WHO methodology: recommendations for rational prescribing

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20183941 ◽

2018 ◽

Vol 7 (10) ◽

pp. 2021

Author(s):

Iram Shaifali ◽

Rajib Karmakar ◽

Shalini Chandra ◽

Santosh Kumar

Keyword(s):

Drug Utilization ◽

Atypical Antipsychotics ◽

Essential Medicine ◽

Uttar Pradesh ◽

Cross Sectional ◽

Prescribing Indicators ◽

Male Predominance ◽

Rational Prescribing ◽

Prescribing Trends ◽

Prescribing Trend

Background: Utilization pattern of antipsychotics has undergone a major shift as the newly introduced atypical antipsychotics have heralded the market. Hence continuous studies on current prescribing trends are needed to provide most updated, effective and rational treatment of psychoses.Methods: This cross-sectional prospective study was conducted at Rohilkhand Medical College and Hospital, Bareilly, Uttar Pradesh, India. OPD tickets of the department of psychiatry for the year 2016-2017 were evaluated for a total of 310 cases. These prescriptions were used to determine the drug utilization of antipsychotics and for their appropriateness against the WHO recommended core prescribing indicators.Results: A total of 310 patients satisfied the inclusion criteria and a male predominance was seen (male:female= 1.3:1). The most common psychotic disorder diagnosed was schizophrenia (44%). Majority of the patients (76%) received monotherapy and the prescribing trend showed a higher use of atypical antipsychotics (89%) over typical ones (11%). The most commonly prescribed anti-psychotic drugs were olanzapine (31%), followed by risperidone (26%). On analysing prescriptions according to the WHO core prescribing indicators it was observed that average number of antipsychotics prescribed per prescription was 1.32. 24% of drugs were prescribed by generic name and 5.2% were administered via injectable route. Drugs prescribed from National list of Essential Medicine, 2015 constituted 46%.Conclusions: The high inclination towards the use of atypical antipsychotics observed in our study correlates with the global changing trends in the treatment of schizophrenia. WHO prescribing indicators should be adhered to, to impart rational prescribing.

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