scholarly journals Drug utilization pattern of analgesics as a teaching tool for rational therapy to MBBS students in a medical college at Dehradun, Uttarakhand, India

2017 ◽  
Vol 6 (4) ◽  
pp. 842
Author(s):  
Mirza Atif Beg ◽  
Shakti B. Dutta ◽  
Shalu Bawa ◽  
Amanjot Kaur ◽  
Subhash Vishal ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Medical Curriculum ◽  
Essential Medicine ◽  
Fixed Dose ◽  
Prescribing Practices ◽  
Prescribing Pattern ◽  
Medical College ◽  
Drug Utilization Studies ◽  
Rational Therapy ◽  
Drug Utilization Research

Background: As a need to introduce Clinical Pharmacology at the undergraduate level the drug utilization studies (DUS) offer useful methods for teaching and training in drug therapy. The indiscriminate use of medicines results in unwanted side effects, drug interactions. Thus keeping this view in mind, this drug utilization research was set to evaluate the prescribing pattern of analgesics to impart certain basic skills to MBBS students which will form an integral component of practicing rational therapeutics.Methods: The retrospective study was conducted by Pharmacology department in SGRRIM and HS. A total of 726 prescriptions were collected by 2nd professional MBBS students entering 5th semester and randomly evaluated for prescribing pattern using WHO drug use indicators.Results: A total of 726 prescriptions were analyzed. Male:Female ratio was 470:256(1.8:1). Age wise distribution of patients 0-15years 122(16.80%), 16-30 years 139(19.41%), 31-45years 242 (33.33%), 46-60 years 113(15.56%) and >60years 110 (15.15%). A total of 4663 drugs were prescribed. 435(9.32%) were analgesics. 208 (47.81%) Paracetamol, 66 (15.17%) Tramadol, 62(14.25%) Aceclofenac, 51 (11.72%) Diclofenac, 46 (10.57%) Ibuprofen and 2(0.45%) Buprenorphine were prescribed. 301 (69.20%) Oral drugs and 134 (30.80%) Injectable were prescribed. 108 (24.83%) Numbers of Fixed dose combinations. 0.60 of analgesics were prescribed per prescription. 381 (87.59%) analgesics were prescribed from National Essential Medicine list 2015. 369 (84.83%) drugs were prescribed by brand names.Conclusions: The main purpose of undergraduate medical curriculum is to develop the requisite diagnostic and therapeutic skills of a basic doctor. Such type of drug utilization studies is set with the objective to encourage rational prescribing, and to identify good and bad prescribing practices.

scholarly journals Pattern of drug utilization in pediatric out patient department of a tertiary care teaching hospital

2020 ◽  
Vol 9 (11) ◽  
pp. 1661
Author(s):  
Rekha M. B. ◽  
Hemamalini M. B. ◽  
Basavaraj Bhandare
Keyword(s):  
Drug Utilization ◽  
Tertiary Care ◽  
Age Groups ◽  
Prescribing Pattern ◽  
Medical College ◽  
Nasal Decongestants ◽  
Rational Drug ◽  
Paediatric Age ◽  
Paediatric Outpatient ◽  
Drug Utilization Studies

Background: Drug utilization studies have special significance among paediatric age groups as infant and children represent about 42% of the population in developing countries. This is the vital period of rapid growth and development. Therefore, drugs should be used very cautiously and rationally among these sub groups. The present study is conducted to analyse the prescribing pattern of drugs in paediatric age group for various illnesses. Methods: It was a prospective observational study, conducted in paediatric outpatient department of Raja Rajeswari medical college and research hospital for a period of 6 months after obtaining approval from institutional ethical committee. Descriptive statistical was used to determine the frequency, percentages, mean and standard deviation.Results: In the present study, fever (30.8%) followed by respiratory diseases were most common diseases seen. The commonly used drugs include antipyretics (66%), antimicrobials (53.6%), cough syrups (34.4%), antihistaminic (31.2%) and nasal decongestants (23.2%). Prescribing indicator shows existence of polypharmacy. Prescribing drugs by generic name was seen only in 8.1% and 47.82% of the drugs were prescribed from EDL. The frequency of use of injectables in our study was 5.8%. Conclusions: Irrational use of antibiotics and polypharmacy needs to be curbed. Prescribing drugs in their generic name and prescribing drugs from EDL need to be promoted. The present prescribing pattern can be improved by advocating rational drug prescribing, patient education and improving hospitals.

scholarly journals Prescription Pattern In Hypertensive Patients In A Tertiary Care Teaching Hospital, Dhaka, Bangladesh

2018 ◽  
Vol 8 (2) ◽  
pp. 39-43
Author(s):  
Udoy Shankar Roy ◽  
Nazibur Rahman Khandaker ◽  
Saleh Uddin ◽  
Murshidur Rahman Khan ◽  
Nihar Ranjan Sarker
Keyword(s):  
Drug Utilization ◽  
Ace Inhibitors ◽  
Antihypertensive Drugs ◽  
Angiotensin Receptor Blockers ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Fixed Dose ◽  
Drug Prescribing ◽  
Prescribing Pattern ◽  
Hypertensive Patients

Background: Irrational drug prescribing is a common practice globally; it results in increased morbidity, mortality & economic burden on society. Drug utilization studies are an important tool to promote rational prescribing.Aims & Objective: To study on drug prescribing pattern in hypertensive patients.Materials and Methods: A drug utilization study was conducted in hypertensive patients by the department of cardiology in OPD at Shaheed Suhrawardy Medical college hospital for 6 months. 645 prescriptions were evaluated for prescribing pattern by using WHO drug use indicators.Results: 645 prescriptions were analyzed. A total of 1828 drugs were prescribed. 697 (38.13%) antihypertensive, 243 (13.30%) anti diabetics, 174 (9.52%) non-steroidal anti-inflammatory drugs (NSAIDs), 154 (8.44%) statins, 114 (6.24%) thyroid hormone, 54 (2.95%) anti-anxiety/ antidepressants and 392(21.44%) miscellaneous drugs were prescribed. 697 antihypertensive drugs were prescribed. 234 (33.57%) angiotensin receptor blockers (ARBs), 117 (16.79%) angiotensin converting enzyme (ACE) inhibitors, 95 (13.63%) Beta blockers, 83 (11.91%) Calcium channel blockers 168 (24.10%) Fixed dose combinations (FDCs) of antihypertensive were included. 2.83 drugs were prescribed per prescription. 225 (32.28%) antihypertensive were prescribed from essential medicine list.Conclusion: Most commonly prescribed drugs were ARBs and ACE inhibitors. Rational prescribing requires consideration to dose and duration and interaction with other medications.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 39-43

scholarly journals Study of drug utilization trends in respiratory tract infections in a tertiary care teaching hospital: a retrospective study

2017 ◽  
Vol 6 (11) ◽  
pp. 2583
Author(s):  
Avula Naveen ◽  
M. R. Sravani
Keyword(s):  
Health Care ◽  
Respiratory Tract ◽  
Drug Utilization ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Prescribing Patterns ◽  
Fixed Dose ◽  
Drug Utilization Studies ◽  
Tract Infections

Background: Drug utilization studies play crucial role in the health sector and ultimately it provides insight into the efficiency of drug use and results of such research can be used to help to set priorities for the rational use of medicines and allocation of health care budgets. Respiratory tract infections (RTIs) contributing to significant mortality and morbidity of populations especially in developing countries like India. Polypharmacy and irrational prescription are significant negative fallouts in treatment of RTIs. Keeping in view of this, our study was undertaken to analyze the drug utilization pattern of RTIs.Methods: The study was conducted at Gandhi Hospital, after obtaining permission from the Institutional Ethics Committee. We have collected data of 600 case records of the patients diagnosed with respiratory tract infection and evaluated for prescribing patterns in consonance with WHO indicators.Results: Out of the total case records 348 (58%) were of male patients and 252 (42%) of female patients. Age wise distribution was done; 79 (13.16%) 0-15 years, 46 (7.67%) 16-30 years, 123 (20.50%) 31-45 years, 194 (32.33%) 46-60 years and 158 (26.33%) patients belongs to >60 years of age group respectively. A total of 4682 drugs were prescribed, 2468 (52.71%) antibiotics, 768 (16.4%) bronchodilators, 581 (12.4%) corticosteroids, 323 (6.89%) antacids, 542 (11.57%) in miscellaneous category respectively. With regard to formulations 2463 (52.60%) oral, 1463 (31.24%) injectable and 756 (16.14%) inhalational drugs were prescribed. Numbers of Fixed dose combinations were 712 (15.20%). 7.8 drugs were prescribed per prescription. 2493 (53.24%) drugs were prescribed from National Essential Medicine List. 4168 (89.02%) drugs were prescribed by their brand names.Conclusions: Prescription of drugs with branded names, Irrational prescribing, poly pharmacy were observed in our study. So there is an urgent need for creating awareness among the health care professionals regarding rational prescription by using data from from drug utilization studies. 

scholarly journals Prescribing trends in respiratory tract infections in a tertiary care teaching hospital

2017 ◽  
Vol 5 (6) ◽  
pp. 2588 ◽  
Author(s):  
Mirza A. Beg ◽  
Shakti B. Dutta ◽  
Shalu Bawa ◽  
Amanjot Kaur ◽  
Subhash Vishal ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Drug Utilization ◽  
Respiratory Tract Infections ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Fixed Dose ◽  
Utilization Pattern ◽  
Prescribing Pattern ◽  
Prescribing Trends ◽  
Tract Infections

Background: Respiratory tract infections are a major cause of morbidity and mortality in developing countries. Polypharmacy and irrational prescribing in respiratory diseases are common practice worldwide. Keeping in consideration this scenario, present study was undertaken to analyze the drug utilization pattern of respiratory tract infections.Methods: This drug utilization study was conducted by Pharmacology department at SGRRIM & HS to analyze drug utilization pattern of respiratory infections. A total of 585 prescriptions were collected from hospital and randomly evaluated for prescribing pattern using WHO drug indicators.Results: A total of 585 prescriptions were analyzed. Male:Female ratio was 1:0.77. Age wise distribution was done; 81(13.84%) 0-15 years, 54(9.23%) 16-30 years, 198(33.84%) 31-45 years, 75(12.82%) 46-60 years and 177(30.25%) patients belongs to >60 years of age group respectively. A total of 4869 drugs were prescribed, 2754(56.56%) antibiotics, 675(13.8%) bronchodilators, 630(12.93%) corticosteroids, 303(6.22%) antacids, 507(10.41%) in miscellaneous category respectively. 2562(52.61%) oral, 1491(30.62%) injectable and 816(16.75%) inhalational drugs were prescribed. Numbers of Fixed dose combinations were 645(13.24%). 8.32 drugs were prescribed per prescription. 2409(49.47%) drugs were prescribed from national essential medicine list 2015. 4320(88.72%) drugs were prescribed by their brand names.Conclusions: Irrational prescribing and polypharmacy was observed. The drug utilization studies are important tool to sensitize and increases awareness among physicians, which ultimately improves rational prescribing and patient care.

scholarly journals A PROSPECTIVE STUDY ON ANTIMICROBIAL UTILIZATION PATTERN IN OUTPATIENT DEPARTMENT AT TERTIARY CARE HOSPITAL, PUNE, INDIA.

2018 ◽  
Vol 11 (5) ◽  
pp. 131
Author(s):  
Sarang A Deshmukh ◽  
Yashasvi Agarwal ◽  
Harshita Hiran ◽  
Uma Bhosale
Keyword(s):  
Antimicrobial Agents ◽  
Demographic Data ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Antibiotic Use ◽  
Oral Dosage ◽  
Fixed Dose ◽  
Care Hospital ◽  
Prescribing Practices ◽  
Cross Sectional

 Objective: The objective of the study was to evaluate antimicrobial prescription pattern in outpatient departments.Method: This was a prospective, cross-sectional and observational study over 12 weeks total 400 prescriptions of either gender and age; containing antimicrobial agents (AMAs) were analyzed for demographic data and the WHO prescribing indicators.Results: Most of prescription were given to men (n=262). The most common group of AMA used was Cephalosporins (n=141, 35.25%); of which Ceftriaxone was most commonly prescribed (n=73, 18.25%). 10 AMAs were from the WHO essential medicine list AMAs. Men outnumbered women in prescribing antibiotics (n=262 vs. 138). Most of AMAs receivers were between 26 and 35 years (n=128, 32%). Amoxicillin+Clavulanic acid fixed-dose combination was most common (n=84, 21%). Most of the prescriptions were containing four drugs per prescriptions (n=130, 32.5%). Only 10% of the prescription was given by generic name and rest 90% were given by brand name. Oral dosage form of AMAs was predominant (n=340, 85%). Vitamins and supplement were most common comedication received by patients.Conclusion: Antibiotic use was found to be reasonable and rational in most of the cases. However, still, prescribers should improve prescribing practices and make it more rational.

scholarly journals A Retrospective Drug Utilization Study on Psychiatric Illness in a Tertiary Care Teaching Hospital

2021 ◽  
pp. 148-153
Author(s):  
I. Jerlin Michelle ◽  
E. Dhanushri ◽  
V. Nidhish RAJ ◽  
Muhammad Aslam Syed ◽  
A. Priyadharshini ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Psychotropic Drugs ◽  
Psychiatric Illness ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Increased Risk ◽  
Drug Utilization Studies ◽  
Standard Value

Psychiatric disorders are now widely recognized as a major contributor to the global burden of disease. It has been described that there is an increased risk of adverse effects when more than one psychotropic drug is prescribed. Knowledge of the pattern of utilization of drugs in the general population can be achieved through the conduct of drug utilization studies. The present study has therefore been conducted to observe the pattern of drug use in psychiatry patients in a tertiary care hospital. Aim and Objective: To assess the epidemiology of various psychiatric illnesses among the study population To assess the Prescribing Pattern of drugs in Psychiatric Illness. To assess the drug-drug interactions in the prescription using MICROMEDEX. Methodology: A retrospective descriptive observational study was performed in a tertiary care hospital. A total of 100 prescriptions were collected from MRD.  Results: The study reported that 66% of patients were males and 34% were females. The average number of drugs and psychotropic drugs per prescription is six and four respectively. Around 61.98% of drugs in the prescription are psychotropic drugs, among that 40.17% of benzodiazepines are majorly used, followed by 34.27% of antipsychotics. Almost 95 prescriptions had a minimum of one drug-drug interaction.  The average number of psychotropics per prescription was higher than in studies. The average number of drugs per prescription was 5.84, which lead to polypharmacy. Conclusion: Using WHO indicators prescription analysis was done and it showed some deviation from the standard value which can be improved. Polypharmacy was noted in this study. Most of the drug is prescribed in the brand name which should be avoided.

scholarly journals Drug utilization pattern in Schizophrenia

2019 ◽  
Vol 8 (7) ◽  
pp. 1572
Author(s):  
Elza Joy Munjely ◽  
Bindu Latha Nair R. ◽  
Varghese P. Punnoose
Keyword(s):  
Economic Impact ◽  
Drug Utilization ◽  
Drug Cost ◽  
Antipsychotic Drugs ◽  
Inclusion Criteria ◽  
Prescribing Pattern ◽  
Prescribing Indicators ◽  
Prescription Pattern ◽  
Medical College ◽  
Schizophrenic Patients

Background: Pharmacotherapy is the mainstay of treatment in schizophrenia. The economic impact of this illness is wide ranging, long lasting and huge. The emergence of newer antipsychotics has changed the prescribing pattern. Purpose of this study is to determine the prescription pattern of antipsychotic drugs and to analyse the drug utilization in patients with schizophrenia based on WHO prescribing indicators.Methods: A descriptive study was conducted for a period of 1-year duration at inpatient Department of Psychiatry of a Government Medical College in Kerala, India among 230 schizophrenic patients. The case sheets of patients meeting inclusion criteria were scrutinised to find out the antipsychotic prescription pattern and drug utilization was analysed using WHO prescribing indicators. Analysis was done using descriptive statistics.Results: Newer antipsychotics (55.2%) were prescribed slightly more in preference to older antipsychotic (44.8%) drugs. Out of the newer drugs prescribed olanzapine (20.9%) was prescribed the most followed by risperidone (18%). Haloperidol (22.9%) was the most frequently prescribed older antipsychotic. Majority (71.3%) of the patients were given more than one antipsychotics during the hospital stay. Trihexyphenidyl (27.9%) was the most frequently co-prescribed drug with antipsychotics. Average number of drugs per encounter was 4.19, 73.4% of the drugs were prescribed in their generic name, 50.4% of the encounters were with an injection prescribed. 44.4%of the drugs were prescribed from the EDL (WHO-19th edition). Average drug cost per encounter was Rs.45.43. Percentage of drug cost spent on injections was 8.44%.Conclusions: Newer antipsychotics were more prescribed for schizophrenia of which olanzapine was the commonest. Newer antipsychotics are preferred because of their propensity to cause less side effects and more efficacy. Study of pattern of drug utilization is useful for measuring the economic impact of drug use among patients thereby facilitating rational prescribing.

Evaluation of an outpatient department (OPD)-based prescribing pattern of fixed-dose combinations in a tertiary care institute in Central India

2020 ◽  
Vol 31 (3) ◽  
Author(s):  
Satish Chandel ◽  
Niket Rai ◽  
Sadashivam Balakrishnan ◽  
Ratinder Jhaj ◽  
Akash Vishwe ◽  
...  
Keyword(s):  
Descriptive Analysis ◽  
Tertiary Care ◽  
Essential Medicine ◽  
Central India ◽  
Fixed Dose ◽  
Medical Sciences ◽  
Prescribing Pattern ◽  
Prescribing Trends ◽  
Inflammatory Drugs ◽  
Male Patients

AbstractBackgroundFixed-dose combinations (FDCs) are being widely prescribed for the treatment of various disorders in India. However, not all FDCs are rational. To know the awareness of physicians in prescribing rational FDCs was the need of the hour in order to assess the prescribing trends and rationality of FDCs. Eventually, this will help to formulate the guideline for rational use of FDCs.MethodsThis was a prospective observational study conducted in All India Institute of Medical Sciences Bhopal, MP, India. Prescriptions were collected over a period of 2 months by the convenience sampling method from hospital pharmacy. The data were subjected to descriptive analysis using Microsoft Excel and Graph Pad Prism. Results were expressed in mean ± standard deviation (SD), percentages and 95% confidence interval.ResultsA total of 2496 drugs were prescribed in 1008 prescriptions, of which 945 (37.82%) were FDCs with an average of 0.93 ± 0.94 (mean ± SD) per prescription. Of 945, 67 (7.09%) were included in National List of Essential Medicine 2015 considered as rational. The number of prescriptions containing one or more FDCs was 629 (62.40%). FDCs were more frequently prescribed to male patients (54.92%) and in the age group of 18–30 years (33.44%). FDCs containing a proton pump inhibitor were prescribed most frequently (16.29%) followed by nonsteroidal anti-inflammatory drugs (13.96%) and multivitamins (7.83%).ConclusionsPrescribing irrational FDCs was very common, and hence there is an obvious need to update our prescribers about the irrationality of FDC and motivate them to develop a habit of rational prescribing.

Drug Utilization Study Methodologies: National and International Perspectives

1987 ◽  
Vol 21 (12) ◽  
pp. 994-1001 ◽  
Author(s):  
Abraham G. Hartzema ◽  
Miquel S. Porta ◽  
Hugh H. Tilson ◽  
Joaquima Serradell ◽  
Darrel C. Bjornson ◽  
...  
Keyword(s):  
Drug Utilization ◽  
Defined Daily Dose ◽  
Drug Utilization Study ◽  
International Perspectives ◽  
Drug Databases ◽  
Methodological Rigor ◽  
Daily Dose ◽  
Consumption Rates ◽  
Drug Utilization Studies ◽  
Drug Utilization Research

This paper in the series on pharmacoepidemiology describes the history, development, and present status of drug utilization activities. The various methodologies employed in drug utilization studies are evaluated and presented along with a listing of the principal drug databases available for drug utilization research. An analysis is presented comparing the validity of drug consumption rates based on individual patient usage or drug cost data as adopted in North America and the defined daily dose unit as developed in Europe. Drug utilization derives its importance in pharmacoepidemiology from the fact that it provides the methodological rigor for defining the denominator data needed in pharmacoepidemiological research.

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