EVALUATION OF THE EFFECTIVENESS OF REHABILITATION OF PATIENTS WHO HAVE UNDERGONE ONMC, BASED ON THE ANALYSIS OF THE QUALITY OF LIFE OF PATIENTS

Author(s):  
Ирина Сергеевна Добрынина ◽  
Елена Юрьевна Есина ◽  
Анна Александровна Зуйкова ◽  
Елена Анатольевна Ханина ◽  
Арина Андреевна Кудинова

В данной работе оценивалась эффективность реабилитационных мероприятий, проводимых в амбулаторно-поликлинических условиях через 2-3 недели от момента первого обращения у пациентов с перенесённым острым нарушением мозгового кровоснабжения (ОНМК), путем изучения комплекса физиологических, психологических и социальных нарушений, оказывающих влияние на их качество жизни. Было проведено обследование 43 пациентов, перенесших ОНМК, с использованием индекса Бартел и специализированного опросника «Stroke-Adapted Sickness Impact Profile». Всего в исследовании приняло участие 43 пациента с ОНМК (средний возраст 63,5±7,6 лет), находящихся на амбулаторно-поликлиническом этапе оказания медицинской помощи. В ходе исследования были выявлено, что показатели качества жизни впервые обратившихся пациентов и пациентов, уже проходящих курс реабилитации в течении 2-3 недель, существенно отличались. За период прохождения курса реабилитации отмечено общее улучшение во всех группах нарушенных функций ─ физиологических, психических и социальных, и повышение показателей качества жизни пациентов. Полученные сведения ещё раз подтверждают необходимость особого внимания к вопросам третичной профилактики среди пациентов, пострадавших от ОНМК, врачами поликлинического звена здравоохранения In this work, we evaluated the effectiveness of rehabilitation measures carried out on an outpatient basis 2-3 weeks after the first treatment in patients with acute cerebrovascular accident (stroke), by studying a set of physiological, psychological and social disorders that affect their quality of life. A total of 43 patients who underwent stroke were examined using the Barthel index and the specialized Stroke - Adapted Sickness Impact Profile questionnaire. A total of 43 patients with ONMC (average age 63.5±7.6 years) who are at the outpatient stage of medical care took part in the study. The study revealed that the quality of life indicators for first-time patients and patients already undergoing rehabilitation for 2-3 weeks were significantly different. Over 2-3 weeks of the rehabilitation course, a general improvement was noted in all groups of impaired functions ─ physiological, mental and social, ─ and an increase in the quality of life of patients. The information obtained once again confirms the need for special attention to tertiary prevention among patients affected by stroke, by doctors of the outpatient healthcare department

Author(s):  
Mohamad Hossein Pourhanifeh ◽  
Kazem Abbaszadeh-Goudarzi ◽  
Mohammad Goodarzi ◽  
Sara G.M. Piccirillo ◽  
Alimohammad Shafiee ◽  
...  

: Melanoma is the most life-threatening and aggressive class of skin malignancies. The incidence of melanoma has steadily increased. Metastatic melanoma is greatly resistant to standard anti-melanomatreatments such as chemotherapy, and 5-year survival rate of cases with melanoma who have metastatic form of disease is less than 10%. The contributing role of apoptosis, angiogenesis and autophagy in the pathophysiology of melanoma has been previously demonstrated. Thus, it is extremely urgent to search for complementary therapeutic approachesthat couldenhance the quality of life of subjects and reduce treatment resistance and adverse effects. Resveratrol, known as a polyphenol component present in grapes and some plants, has anti-cancer properties due to its function as an apoptosis inducer in tumor cells, and anti-angiogenic agent to prevent metastasis. However, more clinical trials should be conducted to prove resveratrol efficacy. : Herein, for first time, we summarize current knowledge of anti-cancerous activities of resveratrol in melanoma.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Domenico Cuda ◽  
Sara Ghiselli ◽  
Alessandra Murri

Abstract Background Prevalence of hearing loss increases with age. Its estimated prevalence is 40–50 % in people over 75 years of age. Recent studies agree that declinein hearing threshold contribute to deterioration in sociality, sensitivity, cognition, and quality of life for elderly subjects. The aim of the study presented in this paper is to verify whether or not rehabilitation using first time applied Hearing Aids (HA) in a cohort of old people with hearing impairment improves both speech perception in a noisy environment over time and the overall health-related quality of life. Methods The monocentric, prospective, repeated measurements, single-subject, clinical observational study is to recruit 100 older adults, first-time HA recipients (≥ 65 years).The evaluation protocol is designed to analyze changes in specific measurement tools a year after the first HA usage in comparison with the evaluation before HA fitting. Evaluations will consist of multiparametric details collected through self-report questionnaires completed by the recipients and a series of commonly used audiometric measures and geriatric assessment tools. The primary indicator of changes in speech perception in noise to be used is the Italian version of Oldenburg Satz (OLSA) test whereas the indicator of changes in overall quality of life will be the Assessment of Quality of Life (AQoL) and Hearing Handicap Inventory for the Elderly (HHIE) questionnaires. The Montreal Cognitive Assessment (MoCA) will help in screening the cognitive state of the subjects. Discussion The protocol is designed to make use of measurement tools that have already been applied to the hearing-impaired population in order to compare the effects of HA rehabilitation in the older adults immediately before first HA usage (Pre) and after 1 year of experience (Post). This broad approach will lead to a greater understanding of how useful hearing influences the quality of life in older individuals, and therefore improves potentials for healthy aging. The data is to be analyzed by using an intrasubject endpoint comparison. Outcomes will be described and analyzed in detail. Trial registration This research was retrospectively registered underno. NCT04333043at ClinicalTrials.gov (http://www.clinicaltrials.gov/) on the 26 March 2020. This research has been registered with the Ethics Committee of the Area Vasta Emilia Nord under number 104, date of approval 17/07/2017.


2013 ◽  
Vol 11 (1) ◽  
pp. 207 ◽  
Author(s):  
Serena Iacono Isidoro ◽  
Adriana Salvaggio ◽  
Anna Lo Bue ◽  
Salvatore Romano ◽  
Oreste Marrone ◽  
...  

2015 ◽  
Vol 26 (3) ◽  
pp. 415-425 ◽  
Author(s):  
Morten Schrøder ◽  
Kirsten A. Boisen ◽  
Jesper Reimers ◽  
Grete Teilmann ◽  
Jesper Brok

AbstractPurposeWe performed a systematic review and meta-analysis of observational studies assessing quality of life in adolescents and young adults born with CHD compared with age-matched controls.MethodsWe carried out a systematic search of the literature published in Medline, Embase, PsychINFO, and the Cochrane Library’s Database (1990–2013); two authors independently extracted data from the included studies. We used the Newcastle–Ottawa scale for quality assessment of studies. A random effects meta-analysis model was used. Heterogeneity was assessed using the I2-test.ResultsWe included 18 studies with 1786 patients. The studies were of acceptable-to-good quality. The meta-analysis of six studies on quality of life showed no significant difference – mean difference: −1.31; 95% confidence intervals: −6.51 to +3.89, I2=90.9% – between adolescents and young adults with CHD and controls. Similar results were found in 10 studies not eligible for the meta-analysis. In subdomains, it seems that patients had reduced physical quality of life; however, social functioning was comparable or better compared with controls.ConclusionFor the first time in a meta-analysis, we have shown that quality of life in adolescents and young adults with CHD is not reduced when compared with age-matched controls.


2021 ◽  
Vol 59 (1) ◽  
pp. 31-35
Author(s):  
N. Trizna ◽  
Z. Kaliadich ◽  
E. Zhaleika ◽  
A. Evmenenko

Study of the quality of life indicators is an important part of a comprehensive analysis of new diagnosis, treatment, and prevention methods. It can serve as an additional criterion for selecting individual therapy or rehabilitation, examining the ability to work, and identifying psychological problems. Purpose of the study: The authors took a clinical case to demonstrate the use of внтфьшс monitoring of the quality of life indicators for the assessment of surgical and reconstructive treatment outcome for oral and oropharyngeal cancer. Results: The anticancer treatment effects were reflected in the physical functioning score according to the EORTC QLQ-C30 questionnaire (reduced to 80 points) and some symptomatic scores according to the EORTC QLQ-C30 and EORTC QLQ-H & N35 questionnaires. Medical rehabilitation measures resulted in positive dynamics of physical functioning scores according to the EORTC QLQ-C30 questionnaire (increase to 93.3 points) and symptomatic scores according to the EORTC QLQ-H & N35 questionnaire related to nutrition. At that, the patient has stopped having difficulty eating in public places; his body weight increased. The absence of pain and refusal to take analgesics also testified to successful treatment and improved quality of life. Conclusion: A subjective assessment of the various quality of life aspects in a particular patient provides valuable information about the individual response to the conducted treatment.


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