The Improvement of Neuropathy and Balance after Combination of Indonesian Diabetic and Indonesian Diabetic Foot Exercise on Diabetic Peripheral Neuropathy

Author(s):  
Putri Dyah Utami Ryadi ◽  
Tertianto Prabowo ◽  
Irma Ruslina Defi

Background: Half of people with Type 2 Diabetes Mellitus (Type 2 DM) developed diabetic neuropathyat 25 years after being diagnosed and around 75% of the neuropathy were diabetic peripheral neuropathy(DPN), that associated with balance disturbance. This study aimed to know the effect of combining Indonesiandiabetic exercise (Senam Diabetes Indonesia/SDI) and Indonesian diabetic foot exercise (Senam Kaki DiabetesIndonesia/SKDI) on improvement of diabetic neuropathy and balance score in people with Type 2 diabeticperipheral neuropathy.Methods: Design study was a quasi-experimental study with pre-posttest design. The participants were Type 2DM patients aged 40-65 years old, with DPN confirmed based on Indonesian version of Diabetic NeuropathySymptom (DNS-INA) >1 or Indones ian version of Diabetic Neuropathy Exmination (DNE-INA) >3, who didnot do exercise regularly. All participants had Berg Balance Scale (BBS) score within 41-55, and the randomperipheral blood glucose within 100-250mg/dL. The BBS, DNE-INA, and DNS-INA score were evaluatedbefore and after 12 weeks of excercise.Results: There were 6 women aged 52-65 years. The mean of BBS, DNS-INA, and DNE-INA scores beforeand after intervention were 54.33±1.032 and 55.16±1.329 (p=0.025), 2.50±1.048 and 1.50±0.836 (p=0.063),3.66±1.505 and 1.33±0.816 (p=0.041), respectively.Conclusion: There were improvement of Berg Balance Score and Diabetic Neuropathy Score after thecombination of Diabetic exercises.Keywords: Berg Balance Score, diabetic neuropathy score, Indonesian Diabetic Exercise, Indonesian FootDiabetic Exercise

Author(s):  
Ani S. Todorova ◽  
Edward B. Jude ◽  
Rumyana B. Dimova ◽  
Nevena Y. Chakarova ◽  
Mina S. Serdarova ◽  
...  

The aim of this study was to assess vitamin D status in patients with type 2 diabetes and diabetic foot ulcers (DFU). A total of 242 participants with type 2 diabetes, mean age 59.1 ± 10 years, mean body mass index 31.4 ± 6.3 kg/m2, and estimated glomerular filtration rate ≥45 mL/min/1.73m2, were divided into 2 groups: 73 with DFU (35 with and 38 without active infection) and 169 without DFU (106 with diabetic peripheral neuropathy, 63 without complications). Neuropathy was assessed by 10 g monofilament, Rydel-Seiffer 128 Hz tuning fork, and temperature discrimination. Serum 25(OH)D (25-hydroxy vitamin D) was assessed by ECLIA (electro-chemiluminescence immunoassay) method. Median 25(OH)D level was 12.6 ng/mL (IQR [interquartile range] 9.3-17.6 ng/mL) in the studied cohort. The DFU group presented with lower 25(OH)D level as compared with diabetic patients without foot ulcers (non-DFU group): 11.6 ng/mL (IQR 8.5-15.8 ng/mL) versus 13.5 ng/mL (IQR 9.6-18.6 ng/mL), P = .001; the diabetic peripheral neuropathy subgroup demonstrated lower 25(OH)D level in comparison with participants without complications: 12.5 ng/mL (IQR 9-17.2 ng/mL) versus 15.9 ng/mL (IQR 10.4-20.8 ng/mL), P = .031. This remained significantly different even after correction for age and duration of diabetes. There was no difference in 25(OH)D level between the subgroups according to the presence of active infection. In conclusion, vitamin D deficiency may play a role in the development of diabetes complications.


Geriatrics ◽  
2020 ◽  
Vol 5 (2) ◽  
pp. 33
Author(s):  
Sho Tanaka ◽  
Masahiro Takubo ◽  
Genta Kohno ◽  
Masaru Kushimoto ◽  
Jin Ikeda ◽  
...  

The aim of this study was to investigate factors associated with sarcopenia among elderly patients with poorly controlled diabetes mellitus (DM). We retrospectively analyzed 41 patients with type 2 DM, aged ≥65 years who required diabetes education hospitalization. Patients were classified into two groups according to the presence or absence of a weakened hand grip, and clinical characteristics were compared. Patients with a weakened hand grip (n = 21) scored worse on a mini-mental state examination (24.3 vs. 26.5, p = 0.04), showed a higher prevalence of diabetic peripheral neuropathy (76% vs. 40%, p = 0.03), and had a higher serum phosphorus concentration (3.8 vs. 3.3 mg/dL, p < 0.01) compared to those without a weakened hand grip (n = 20). The serum phosphorus concentration was inversely correlated to hand grip strength (r = −0.501, p < 0.001) among the total of 41 patients. This inverse association was also confirmed after adjusting the effects of estimated glomerular filtration rate, age, and glycated hemoglobin. Thus, cognitive impairment, diabetic peripheral neuropathy, and high serum phosphorus concentrations are associated with hand grip weakness in elderly patients with type 2 DM.


2020 ◽  
Vol 16 (1) ◽  
pp. 35-40
Author(s):  
Rahab Marhoon Alghafri ◽  
Alfred Gatt ◽  
Cynthia Formosa

AIM: The study aimed to investigate the possible relationship between diabetic peripheral neuropathy (DPN) and the development of depressive symptoms in patients with type 2 diabetes mellitus (T2D). METHODS: A comparative nonexperimental study was conducted. Ninety-five T2D individuals aged 65 years and more were recruited. The sample was divided into two groups: 50 participants with T2D and without DPN and 45 participants with T2D and DPN. The Patient Health Questionnaire 9 (PHQ-9) was used to collect information about low mood and depression symptoms in the subjects recruited. RESULTS: Participants with DPN recorded higher scores on PHQ-9 than those with T2D only. The mean PHQ-9 score for the DPN group (6.09) was significantly higher than that for the T2D only group (2.24) (p < 0.001). Participants with DPN were more likely to have mild to moderate or moderately severe low mood and depression symptoms than T2D only participants who exhibited minimal to no low mood and depressive symptoms. CONCLUSIONS: The association between DPN and depression is confirmed by this study, with significant depressive symptoms found in patients with neuropathy when compared to diabetes patients with no neurological complications. It is therefore important that discomfort and emotional problems caused by DPN should be taken seriously and addressed closely in the management of DPN in order to prevent depression. Also, a change in screening practices to identify patients with diabetes and depressive symptoms is required.


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Daniel Ruscianto ◽  
Linda W. A. Rotty ◽  
Karel Pandelaki

Abstract: Diabetes mellitus (DM) is a metabolic disease characterized by hyperglycemia due to impaired insulin activity, or both. Uncontrolled DM will lead to chronic complication, such as microangiopathy, macroangiopathy. and neuropathy. Diabetic foot is one of the chronic complications. This complication is associated with abnormality of thrombocyte and hematocrit levels that influence the blood flow. This study aimed to find out the profile of thrombocyte and hematocrit levels in patients with type 2 DM with diabetic foot at Prof. Dr. R. D. Kandou Hospital Manado. There were 25 patients type 2 DM with diabetic foot as samples consisted of:10 males (40%) and 15 females (60%). The mean of hematocrit level in males was 35.20% and in females was 28.40%. The mean of thrombocyte level was 391.4 x 103/mm3.Keywords: diabetic foot, thrombocyte, hematocritAbstrak: Diabetes melitus (DM) merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia yang terjadi karena kelainan sekresi insulin, kerja insulin atau keduannya. Hiperglikemi pada DM yang tidak terkontrol menyebabkan komplikasi kronis, seperti mikroangiopati,makroangiopati dan neuropati. Kaki diabetes merupakan salah satu komplikasi kronis. komplikasi ini berkaitan dengan kelainan kadar trombosit dan hematokrit yang mempengaruhi peredaran darah. Tujuan penelitian ini adalah untuk mengetahui gambaran kadar trombosit dan hematokrit pada pasien diabetes tipe 2 dengan kaki diabetik di BLU RSUP Prof. R. D. Kandou Manado. Terdapat 25 pasien dengan DM tipe 2 yang memiliki komplikasi kaki diabetes yang menjadi sampel penelitian ini. Berdasarkan distribusi jenis kelamin perempuan sebanyak 15 pasien (60%) dan pada pasien laki-laki sebanyak 10 pasien (40%). Rata-rata kadar hematokrit pasien laki-laki adalah 35.20% dan perempuan adalah 28.40%. Rata rata kadar trombosit pasien adalah 391,4 x 103/mm3.Kata kunci: kaki diabetes, trombosit, hematokrit


2020 ◽  
Vol 7 (7) ◽  
pp. 2129
Author(s):  
Vishnu S. Ravidas ◽  
Samadarsi P. ◽  
Ajayan G.

Background: The present study was conducted to determine the association of sociodemographic parameters, comorbid conditions and complications of diabetes mellitus (DM) with the treatment outcomes of diabetic foot ulcers.Methods: The present prospective observational study enrolled 105 participants aged 30-85 years with diabetic foot ulcers presenting to general surgery department during a period of 18 months. Participants who were terminally ill, who had trophic ulcers of Hansen’s disease and filariasis and its sequelae were excluded. The study was approved by institutional ethics committee and written informed consent was obtained from all study participants. Data was analyzed using R and the test of significance was chi square test, p<0.05 was considered statistically significant.Results: Higher proportion of male participants and those aged between 50-69 years were encountered. Male participants were of higher age and the mean duration of DM in participants with diabetic foot ulcer was 8 years. The mean HbA1C of study participants was 8.1%, 38.1% participants had high plasma glucose. Food deformity was observed in 41% participants. 62.9% and 66.7% participants had diabetic peripheral neuropathy and peripheral arterial disease respectively. The mean time required for healing among participants with diabetic foot ulcers was 45.8 Significant association of major amputation with diabetic peripheral neuropathy (p=0.02), Wagner’s grading (p<0.001) and peripheral arterial disease (PAD) (p=0.006) was observed.Conclusions: The presence of diabetic peripheral neuropathy and PAD were risk factors for major amputations in diabetic foot ulcers. Lower Wagner’s grading was associated with lower chances of major amputation.


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 32-LB
Author(s):  
SHENGPU CHOU ◽  
MIKIKO HARAGUCHI ◽  
HIROYA KOMORI ◽  
KOUHEI WATANABE ◽  
SATOKI TSUICHIHARA ◽  
...  

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