Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer Using Inhibition of NLRP3 Inflammasome in Tumor Microenvironment Leads to Suppression of Metastatic Potential of Cancer Cells

Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

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Role and Importance of Inflammasomes and Immune Pathways in Myeloid Malignancies, Particularly Myelodysplastic Syndromes (MDS)/Acute Myeloid Leukemia (AML) to Better Understand the Disease Pathophysiology and Decipher the Scope of Therapeutic Interventions

10.36811/ojrmi.2021.110040 ◽

2021 ◽

pp. 825-867

Author(s):

Ricardo Gobato ◽

Abhijit Mitra

Keyword(s):

Cancer Research ◽

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Therapeutic Interventions ◽

Tumor Spread ◽

Cancer Research Institute ◽

Keywords Cancer ◽

Immune Pathways ◽

Acute Myeloid ◽

Research Institute

Thanks to work by researchers at the California South University (CSU) Cancer Research Institute (CRI), they may soon have new tools to treat melanoma and other cancers. In an article published last month, members of the Cancer Research Institute (CRI) introduced an intracellular complex. Involved in melanoma-mediated inflammation and leads to tumor growth and progression. The researchers found that by inhibiting NLRP3, they could reduce inflammation and tumor spread. Keywords: Cancer; Cells; Tissues; Tumors; Prevention; Prognosis; Diagnosis; Imaging; Screening, Treatment; Management

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Inhibition of NLRP3 inflammasome in tumor microenvironment leads to suppression of metastatic potential of cancer cells

Scientific Reports ◽

10.1038/s41598-019-48794-x ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 16

Author(s):

Hye Eun Lee ◽

Jin Young Lee ◽

Gabsik Yang ◽

Han Chang Kang ◽

Yong-Yeon Cho ◽

...

Keyword(s):

Tumor Microenvironment ◽

Cancer Cells ◽

Nlrp3 Inflammasome ◽

Metastatic Potential

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T Cell Engineering as Therapy for Cancer and HIV

10.36811/jca.2021.110027 ◽

2021 ◽

pp. 715-752

Author(s):

Elena Locci ◽

Silvia Raymond

Keyword(s):

Cancer Research ◽

T Cell ◽

Cancer Cells ◽

Cancer Biology ◽

The Body ◽

Cell Engineering ◽

Cancer Research Institute ◽

Keywords Cancer ◽

T Cell Engineering ◽

Biology Research

Through T-cell engineering, researchers at the California South University (CSU) Cancer Research Institute (CRI) have shown that tumor growth can be stopped in a variety of cancers and prevented from spreading to other tissues. Findings from this study are the result of decades of research by Professor Alireza Heidari, a member of the Cancer Biology Research Program at the California South University (CSU), who discovered a protein called AH that can inhibit the growth and spread of cancer cells in several different ways. They become in the tissues of the body. Keywords: Cancer; Cells; Tissues, Tumors; Prevention, Prognosis; Diagnosis; Imaging; Screening; Treatment; Management

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