scholarly journals Effect of Tramadol on Hormones and Lipid Peroxidation of male Rabbits

2021 ◽  
pp. 908-913
Author(s):  
Eman, G. A. Allafi ◽  
Om-alsaad E. I. Omar ◽  
Fayrouz. A. Khaled

Tramadol manhandle straightforwardly impacts the discharge of luteinizing hormone and follicular stimulating g hormone from the front pituitary organ that diminishes the common discharge of luteinizing hormone in a pulsatile way, resulting in a negative impact on male testiclesdue to lower levels of testosterone hormone. Animals were orally given 40 mg/kg B.W. doses of tramadol. The tried measurements were given to rabbits each other day for 6 weeks. Tramadol significantly decreased body weight (BW), weight of brain, testes, testosterone, estradiol, follicle stimulating hormone (FSH), luteinizing hormone (LH), triiodothyronine (T3) and thyroxin hormone (T4). While, it caused significant increase in thiobarbituric acid-reactive substances (TBARS) concentrations in plasma, testes and brain. Keywords: Tramadol; Hormone; TBARS; Rabbits

1988 ◽  
Vol 119 (4) ◽  
pp. 525-528 ◽  
Author(s):  
Talaat S. Mahrous ◽  
Atif M. Nakhla

Abstract. Administration of a pharmacological dose of salmon calcitonin into rats (10 MRC U/kg body weight) significantly reduced plasma concentrations of testosterone and estradiol in a time-dependent fashion. This apparently was mediated by a diminished secretion of luteinizing hormone and follicle-stimulating hormone, the levels of which were also significantly reduced after 1 h of calcitonin administration.


Author(s):  
Frah razzaq Kbyeh

 Thirty female mice white used in the experiment for the purpose of knowing the effect of alcoholic extract raw salvia officnalisleaves on the level of sex hormones which were divided animals into three groups experimental rate of ten mice per group dosage group B and C oral daily dose of the extract amount 500 mg / kg of body weight the first group, respectively,in the1000 mg/ Kg of body weight,respectively,either the first set group A treated the same way time and himself as 0.1 ml / g body weight of physiological solution compared to the mind set lasted 30 days dosing was weight when you stop recording the dosage and then kill her blood was collected through a stab heart for the purpose of studies of hormonal (estrogen,progesterone,luteinizing hormone,follicle stimulating hormone and prolactin)extract reflected the impact of the variables studied and related to fertility in the following results compared with the control group. Low body weight was in the doses and the effect of the dose of 1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05. Significant increase in the level of hormones (progesterone,estrogen,luteinizing hormone,follicle-stimulating hormone) in the doses and the effect of the dose of1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05. Significant decrease in the level of the hormone prolactin in the doses and the effect of the dose of 1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05


1983 ◽  
Vol 61 (2) ◽  
pp. 359-364 ◽  
Author(s):  
Pradip Chakraborti ◽  
Deb Kumar Rakshit ◽  
Samir Bhattacharya

Perch thyroid activity fluctuated in different phases of the reproductive cycle, being highest at spawning and lowest at postspawning. Treatment of intact perch with salmon gonadotropin (SG-G100) or ovine luteinizing hormone (LH) (1 μg/100 g body weight) for 15 days markedly enhanced thyroid activity. The extent of stimulation was greater with SG-G 100 than with LH. Follicle-stimulating hormone (FSH) had no effect. Ovarian steroids, 17β-estradiol and estrone (100 ng/100 g body weight), also significantly augmented thyroid activity. There was a striking reduction of thyroid activity as a result of ovariectomy, a decrease that could not be improved by SG-G100; however, estrone or 17β-estradiol supplementation resulted in a significant increase of thyroid activity in comparison with ovariectomized controls. These findings suggest that gonadotropin mediated its stimulatory effect on perch thyroid activity via the release of ovarian steroids.


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