scholarly journals ASSESSMENT OF THE EFFICIENCY OF THE APPLICATION OF THE COWBERRY AND BLUEBARRY PASTE IN COMPLEX TREATMENT OF CHRONIC BACTERIAL PROSTATITIS

2019 ◽  
pp. 7-12
Author(s):  
Юрий Заседа
Keyword(s):  
Symmetric Groups ◽  
Diet Therapy ◽  
Health Clinic ◽  
Control Group ◽  
Complex Treatment ◽  
Chronic Bacterial Prostatitis ◽  
Similar Treatment ◽  
Bacterial Prostatitis ◽  
Survey Results

In order to evaluate the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis, 72 patients of the Men’s Health clinic in Kyiv were examined. According to the survey results, 2 symmetric groups of 23 patients were formed. The main group was treated according to the model: antibiotic therapy, auxiliary pharmacotherapy (venotonic drugs and enzymes), local physiotherapy and diet therapy with the inclusion of cowberry and blueberry pastes. The control group received a similar treatment, but without changing the diet.Evaluating the eff ectiveness of cowberry and blueberry pastes in the complex treatment of chronic bacterial prostatitis shows that patients treated with the inclusion of homogenized cowberry and blueberry pastes in the diet demonstrate a lower intensity of symptoms of chronic bacterial prostatitis (according to the I-PSS scale) 3 months after treatment, namely: “urination urgency” and “subjective reduction in the quality of life” (p=0.03).

scholarly journals The use of Lactobacillus casei DG® prevents symptomatic episodes and reduces the antibiotic use in patients affected by chronic bacterial prostatitis: results from a phase IV study

2021 ◽  
Author(s):  
Tommaso Cai ◽  
Luca Gallelli ◽  
Erika Cione ◽  
Gianpaolo Perletti ◽  
Francesco Ciarleglio ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Symptoms ◽  
Clinical Status ◽  
Well Being ◽  
Antibiotic Use ◽  
Chronic Bacterial Prostatitis ◽  
Symptomatic Recurrence ◽  
Bacterial Prostatitis ◽  
Phase Iv

Abstract Purpose To evaluate the efficacy of Lactobacillus paracasei CNCM I-1572 (L. casei DG®) in both prevention of symptomatic recurrences and improvement of quality of life in patients with chronic bacterial prostatitis (CBP). Methods Patients with CBP attending a single Urological Institution were enrolled in this phase IV study. At enrollment, all patients were treated with antibiotics in agreement with EAU guidelines and then were treated with L. casei DG® (2 capsules/day for 3 months). Clinical and microbiological analyses were carried out before (enrollment, T0) and 6 months (T2) after the treatment. Both safety and adherence to the treatment were evaluated 3 months (T1) after the enrollment. NIH Chronic Prostatitis Symptom Index (CPSI), International Prostate Symptom Score (IPSS) and Quality of Well-Being (QoL) questionnaires were used. The outcome measures were the rate of symptomatic recurrence, changes in questionnaire symptom scores and the reduction of antibiotic use. Results Eighty-four patients were included. At T2, 61 patients (72.6%) reported a clinical improvement of symptoms with a return to their clinical status before symptoms. A time dependent improvement in clinical symptoms with significant changes in NIH-CPSI, IPSS and QoL (mean difference T2 vs T0: 16.5 ± 3.58; − 11.0 ± 4.32; + 0.3 ± 0.09; p < 0.001), was reported. We recorded that L. casei DG® treatment induced a statistically significant decrease in both (p < 0.001) symptomatic recurrence [1.9/3 months vs 0.5/3 months] and antibiotic use [− 7938 UDD]. No clinically relevant adverse effects were reported. Conclusions L. casei DG® prevents symptomatic recurrences and improves the quality of life in patients with CBP, reducing the antibiotic use.

Influence of art therapy in complex treatment on the quality of remission in patients with recurrent depressive disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S559-S559
Author(s):  
V. Korostiy ◽  
S. Hmain
Keyword(s):  
Quality Of Life ◽  
Depressive Disorder ◽  
Art Therapy ◽  
Combined Treatment ◽  
Control Group ◽  
Complex Treatment ◽  
Residual Symptoms ◽  
Remission Period ◽  
Competing Interest

IntroductionAccording to studies done in recent years regarding the treatment of patients with recurrent depressive disorder, a shift of interest from studies evaluating the effectiveness of therapy to the study of remission is seen. According to the literature, complete remission occurs in only 40–50% of patients, in other cases there is residual symptoms.AimsEvaluating the effectiveness of art therapy in treatment in patients with recurrent depressive disorder on the quality of remission.MethodsThe study involved 135 patients: 60 male and 75 female patients aged from 18 to 30 years old. The main group of patients apart the combined treatment also participated in group art therapy with the use of drawing techniques, while the control group – statutory standard therapy. We used clinical, psychopathological, psychodiagnostic and statistical methods.ResultsThe results of the effectiveness of art therapy in complex treatment in patients with recurrent depressive disorder is detected primarily in reducing of the level of anxiety at the early stages of treatment, as well as in reducing of the severity of anhedonia and improving the quality of life in remission period.ConclusionThese results support the use of art therapy in treatment in patients with recurrent depressive disorder during period of active treatment, and after achieving clinical remission contributes to achieving and maintaining high-quality and stable remission with full restoration of quality of life and social functioning.Disclosure of interestThe authors have not supplied their declaration of competing interest.

The Use of Art Therapy in Complex Treatment on the Quality of Remission in Patients with Melancholy in Major Depressive Disorder

2017 ◽  
Vol 41 (S1) ◽  
pp. s777-s777 ◽  
Author(s):  
H. Kozhyna ◽  
V. Korostiy ◽  
S. Hmain ◽  
V. Mykhaylov
Keyword(s):  
Quality Of Life ◽  
Major Depressive Disorder ◽  
Depressive Disorder ◽  
Art Therapy ◽  
Depressive Disorders ◽  
Combined Treatment ◽  
Control Group ◽  
Complex Treatment ◽  
Major Depressive

IntroductionAccording to studies done in recent years regarding the treatment of patients with melancholy in major depressive disorder, a shift of interest from studies evaluating the effectiveness of therapy to the study of remission is seen. Despite significant progress in the development of pharmacotherapy of depressive disorders, difficulty in achieving rapid reduction in depressive symptoms and stable remission in patients with melancholic depression necessitated the search for new approaches to the treatment of this pathology.AimsEvaluating the effectiveness of art therapy in treatment in patients with melancholy in major depressive disorder on the quality of remission.MethodsThe study involved 135 patients – 60 male and 75 female patients aged from 18 to 30 years old. The main group of patients apart the combined treatment also participated in group art therapy with the use of drawing techniques, while the control group – statutory standard therapy.ResultsThe results of the use of art therapy in complex treatment in patients with major depressive disorder is detected primarily in reducing of the level of anxiety at the early stages of treatment (60% of patients have noticed decreasing of melancholic state), as well as improving the quality of life in remission period.ConclusionThese results support the use of art therapy in treatment in patients with melancholy in major depressive disorder during period of active treatment, and after achieving clinical remission contributes to achieving and maintaining high-quality and stable remission with full restoration of quality of life and social functioning.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals IMPACT OF SOME FACTORS ON QUALITY OF LIFE OF ELDERLY CASES WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

2020 ◽  
Vol 74 (2) ◽  
pp. 91-94
Author(s):  
S.V. Turkina ◽  
◽  
A.A. Grishchenko ◽  
N.I. Zhernakova ◽  
T.Yu. Lebedev ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Control Group ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Quality Of Life Indicators ◽  
Survey Results ◽  
The Relationship

40 elderly and senile patients were examined including 20 patients with exacerbation of chronic obstructive pulmonary disease (COPD) of moderate severity (experimental group) and 20 cases without COPD, acute diseases and exacerbations of chronic pathology (control group). Impact of COPD was studied for various aspects of quality of life. It was analyzed the nature and strength of the relationship between of quality of life indicators and biochemical survey results.

scholarly journals The Effects of Individual Diet Therapy on Food Intake, Quality of Life, and Related Serum Proteins in Patients with Breast Cancer: A Randomized Clinical Trial

2021 ◽  
Author(s):  
Azadeh Fallah ◽  
Kiana Parnian ◽  
Hamid Abdolazimi ◽  
Sajjad Tezerji ◽  
Zohreh Mazloom
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Side Effects ◽  
Cancer Patients ◽  
Serum Proteins ◽  
Intervention Group ◽  
Diet Therapy ◽  
Control Group ◽  
Nutritional Needs

Background: In cancer patients, weight loss due to malnutrition has a significant impact on the patients’ treatment and quality of life. This study aimed to determine the appropriate therapeutic strategy to control the side effects of chemotherapy in patients with breast cancer to improve their health, quality of life, and nutritional status. Methods: In our prospective study, we examined gastric cancer patients who were Seventy patients undergoing chemotherapy were included and randomly divided into intervention (n=35) and control groups (n=35). The intervention group received an individualized diet according to their nutritional needs for eight weeks, and the control group received dietary advice on the side effects of chemotherapy. Malnutrition, nutritional barriers, and patients’ quality of life were evaluated by PG-SGA, nutritional barriers, and QLQ-C30 questionnaires. Serum proteins were also assessed at the beginning and the end of the study. Results: The patients’ mean age was 50.91±1.72 years in the intervention group and 51±1.35 in the control group. According to the PG-SGA questionnaire classification, 68.5% of patients had malnutrition at baseline. In the intervention group, the mean score of PG-SGA decreased, which indicated an improvement in patients’ nutritional status. Increased scores in the functional section of QLQC30 and a decrease in the symptom section of this questionnaire indicated the improved quality of life in patients undergoing treatment at the end of the intervention. Albumin (P<0.001) and hemoglobin (P<0.001) levels increased in the intervention group, while there were no significant changes in these variables of the control group. Serum levels of ferritin did not show significant changes in either the intervention or the control group. Conclusion: Identifying nutritional barriers in breast cancer patients and individual diet therapy based on these barriers and nutritional needs reduces nutritional barriers. Consequently, malnutrition would decline, and the quality of life may enhance in these patients.

scholarly journals Oxidative status of prostate and its dynamics against etiotropic antimicrobial chemotherapy in patients with chronic bacterial prostatitis

2019 ◽  
Vol 20 (3) ◽  
pp. 56-65
Author(s):  
О. I. Bratchikov ◽  
Р. A. Dubonos ◽  
I. A. Tyuzikov
Keyword(s):  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Free Radical ◽  
Treatment Group ◽  
Positive Relationship ◽  
Pain Syndrome ◽  
Oxidative Status ◽  
Control Group ◽  
Chronic Bacterial Prostatitis ◽  
Bacterial Prostatitis

The study objective is to investigate some initial characteristics of prostate oxidative status and their dynamics during the course of etiotropic antimicrobial monochemotherapy in patients with chronic bacterial prostatitis (CBP).Materials and methods. The work is based on treatment of 90 men aged 24–46 years (mean age 38.2 ± 1.4 years) with CBP (the treatment group), and 30 clinically healthy men aged 20–45 years (mean age 35.5 ± 1.5 years) (control group). All men underwent the same type of comprehensive examination during the study, and the results of the examination of the men of the control group were taken as reference values of the conditional norm. Complaints and anamnesis were collected. General physical, special urological, microbiological, laboratory, sonographic studies were performed. The etiotropic antimicrobial monochemotherapy was selected according to the results of microbiological studies of the secretion of the prostate gland, and levofloxacin (500 mg within 28 days) was chosen as a base drug for the subgroup of treatment (n = 15) isolated from the treatment group in the 2nd stage of the study. To assess the characteristics of the prostate oxidative status and its dynamics during etiotropic antimicrobial monochemotherapy, various modifications of biochemical studies of the secretion of the prostate were performed (reactive oxygen species (ROS), lipid peroxidation products (diol conjugates, malonic dialdehyde), activity of superoxide dismutase).Results. In patients with CBP in the secretion of the prostate due to increased ROS formation, increased functional activity (free radical aggression), increased reactions of lipid peroxidation and increased functional load on prostatic superoxide dismutase. Antimicrobial monochemotherapy of CBP was characterized by a microbiological efficacy of 86.7 % and was accompanied by a positive dynamics of a number of clinical and laboratory parameters of chronic bacterial prostatitis, however, this did not lead to the complete elimination of pain syndrome and oxidative disorders in the secretion of the prostate, and also did not significantly improve the quality life of patients and prostate secretory function. In patients with CBP a significant positive relationship was found between the amount of ROS and superoxide dismutase activity in the secretion of the prostate (n = 90; r = 0.413; p = 0.001); and the positive relationship between the amount of ROS in the secretion of the prostate and the clinical pain index (n = 90, r = 0.304, p = 0.001), which reflected the essential role of free radical prostatic aggression as an non-infectious component of the multifactorial pathogenesis of the pain syndrome in CBP.Conclusion. The persistence of residual oxidative disorders and functional deficits in the prostate after a standard course of microbial monochemotherapy justifies the advisability of the additional administration of antioxidants and antihypoxic agents in CBP. 

Quality of Life of Parents of Children with Intellectual Disabilities in Croatia

2017 ◽  
Vol 7 (2) ◽  
pp. 43-48 ◽  
Author(s):  
Anja Kovac Misura ◽  
Haris Memisevic
Keyword(s):  
Quality Of Life ◽  
Intellectual Disability ◽  
Intellectual Disabilities ◽  
Educational Status ◽  
Control Group ◽  
Family Quality Of Life ◽  
Significant Difference ◽  
Survey Results ◽  
Children With Intellectual Disability

Abstract The goal of the present study was to examine the quality of life (QOL) of parents of children with intellectual disability. An additional goal was to examine the effects of gender and educational status on the QOL of these parents. The sample for this study consisted of 50 parents of children with intellectual disabilities and 50 parents of children without disabilities as a control group. As A measure of QOL, we used Family Quality of Life Survey. Results have shown that there is a statistically significant difference between the perceived QOL of parents of children with intellectual disabilities and parents of typically developing children. The effects of gender and educational status on QOL of parents of children with intellectual disabilities were also statistically significant. However, there were no interaction effects of gender and educational status on the QOL. Given the lower QOL of parents of children with intellectual disability, it is important to provide them with support programs in order to improve their QOL.

scholarly journals Clinical and experimental rationale for antioxidant therapy of chronic bacterial prostatitis

2020 ◽  
Vol 6 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Oleg I. Bratchikov ◽  
Igor A. Tyuzikov ◽  
Pavel A. Dubonos
Keyword(s):  
Zinc Deficiency ◽  
Antimicrobial Chemotherapy ◽  
Prostate Gland ◽  
Male Rats ◽  
Experimental Simulation ◽  
First Episode ◽  
Control Group ◽  
Chronic Bacterial Prostatitis ◽  
Healthy Men ◽  
Bacterial Prostatitis

Introduction: Literature data prove the important role of oxidative stress in the pathogenesis of Chronic Bacterial Prostatitis (CBP) and its recurrence, which reduces the effectiveness of standard etiotropic therapy of the disease. Aim of study: To improve the results of the pharmacotherapy of CBP by a comprehensive assessment of oxidative disorders in the prostate gland in a clinical and experimental study to provide evidence for antioxidant support. Material and methods: The results of experimental simulation of CBP in 60 male rats and examination of 90 patients with CBP (average age 38.2 ± 1.4; main group) and 30 clinically healthy men (average age 35.5±1.5; control group), which included history-taking, collecting complaints, questioning, general and special examinations, biochemical, cytological, microbiological, sonographic studies. In some experimental animals and patients with CBP, different modes of pharmacotherapy were tested (antimicrobial monochemotherapy; antimicrobial chemotherapy+zinc picolinate; antimicrobial chemotherapy+L–carnitine tartrate in standard doses). The data were processed using descriptive and comparative statistics. Results and discussion: Clinical and experimental findings showed the compensatory nature of the prostatic oxidative disorders after a standard antimicrobial monochemotherapy of the first episode of CBP and their continued persistence with a high risk of decompensation and development of mitochondrial dysfunction after a course of standard antimicrobial monochemotherapy in CBP recurrence. Zinc deficiency in the patients with CBP was detected on average 2.7 times more often than in the healthy men, so zinc determination in the prostatic fluid and subsequent drug compensation should be considered as first–line diagnostic and treatment measures. In the patients with CBP without zinc deficiency, L-carnitine may be an effective alternative to pharmacological correction of the prostatic oxidative disorders. Conclusion: To increase the effectiveness of standard etiotropic therapy of CBP, simultaneous antioxidant support is necessary, using differentiated administration of antioxidants/antihypoxants (zinc or L-carnitine).

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