scholarly journals Levels, Sources and Risk Characterization of Organochlorine Pesticides in Beer Samples from Romania

2020 ◽  
Vol 71 (1) ◽  
pp. 364-370
Author(s):  
Semaghiul Birghila ◽  
Mihaela Mirela Bratu ◽  
Valentina Coatu ◽  
Nicoleta-Alexandra Damir
Keyword(s):  
Gas Chromatography ◽  
Organochlorine Pesticides ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Average Lifetime ◽  
Acceptable Daily Intake ◽  
Risk Characterization ◽  
Daily Dose ◽  
Long Time

The present study describes the analysis of nine organochlorine pesticides (OCPs) occurrence in twenty beer samples commercially marketed and widely consumed in Romania. Levels of these compounds were determined by gas chromatography with electron capture detector (GC-ECD). The results indicated that 20% of the examined samples were contaminated with one OCP residues, while 45% of samples have presented multiple pesticides. Among individual compounds, γ-HCH (Lindane) and p,p, DDE were the main contributors to the total OCP residues, suggesting a long-time persistence of these pesticides in soil, recent usage or uncontrolled penetration from some sources. The contamination frequency with the different OCPs of analysed samples was in the following order: DDTs]Driens]Heptachlor]Lindane]HCB. The average lifetime of a daily dose (LADD) for the total compounds under study, were below the acceptable daily intake (ADI) for individual compounds, ranging between 1.41E-07 and 3.13E-06 mg kg bw-1d-1. Also, hazard quotient were presented with very low values (HQ[1), suggesting that, in the analysed samples, the OCP residues represent no threat to human health.

scholarly journals IDENTIFIKASI DAN PENENTUAN KADAR RESIDU INSEKTISIDA PADA KUBIS DAN TOMAT DI MODOINDING DAN RURUKAN

EUGENIA ◽  
2019 ◽  
Vol 25 (1) ◽  
Author(s):  
Yoakhim Y. E Oessoe
Keyword(s):  
Gas Chromatography ◽  
Yield Components ◽  
Laboratory Data ◽  
Daily Intake ◽  
Plant Diseases ◽  
Acceptable Daily Intake ◽  
Analysis Method ◽  
Negative Effects ◽  
Tomato Plants ◽  
Vegetable Farmers

This research aims to study 1) Maternal effect on the inheritance of yield components of Manado Yellow Use of Insecticides is one way that is very often made vegetable farmersto cope with pest and plant diseases. However, the use of insecticides may give negative effects for consumers of food containing residues of these poisons.Methodology of research is survey and laboratory. Collecting data in the survey was an interview of 20 vegetable farmers, each 10 from Modoinding and 10 from Rurukan that determined purposively. Laboratory data obtainedwith the ways to identify residues in the cabbage and tomatoes from Modoinding and Rurukan , using Gas Chromatography (GC) according to the analysis method of Pusat Pengujian Obat dan Makanan.Vegetable farmers in Modoinding and Rurukan often apply the insecticide organophospate and pyretroid on cabbage and tomato plants. The residues level in ccabbage and tomato from Modoinding and Rurukan far exceed the value of Acceptable Daily Intake of profonefos allowed.

scholarly journals Dietary Intake and Residues of Organochlorine Pesticides in Foods from Hsinchu, Taiwan

1999 ◽  
Vol 82 (3) ◽  
pp. 677-682 ◽  
Author(s):  
Ruey-An Doong ◽  
Chen-Yu Lee ◽  
Yuh-Chang Sun
Keyword(s):  
Organochlorine Pesticides ◽  
Organochlorine Pesticide ◽  
Daily Intake ◽  
Heptachlor Epoxide ◽  
Consumer Health ◽  
Acceptable Daily Intake ◽  
Traditional Markets ◽  
Hch Isomers ◽  
Wet Weight ◽  
Daily Intakes

Abstract The levels of contamination with various organochlorine pesticides (such as total HCH, heptachlor, heptachlor epoxide, aldrin, dieldrin, endrin, endosulfan, and total DDT) of different foods from 3 traditional markets were determined to estimate Taiwanese daily intake of organochlorine pesticides. Of the 18 organochlorine pesticides investigated, α-HCH, β-HCH, lindane, δ-HCH, heptachlor, heptachlor epoxide, dieldrin, endrin, α-endosulfan, p,p′-DDE, and p,p′-DDT were detected at concentrations ranging from 0.26 to 10.2 ng/g wet weight. Contamination with organochlorine pesticides followed the order heptachlor > dieldrin > α-endosulfan > HCH isomers > heptachlor epoxide > DDT. Frequencies of detection of organochlorine pesticide residues ranged from 2.0 to 52.3%. α-Endosulfan was the most frequently detected organochlorine pesticide in the foods analyzed, followed by heptachlor epoxide (47.6%) and α-HCH (38.9%). Estimated daily intakes (EDIs) of organochlorine pesticides from foods were 1.137 μg for total HCH, 2.147 μg for heptachlor, 0.702 μg for heptachlor epoxide, 0.624 μg for endosulfan, 0.098 μg for cyclodiene, and 0.541 μg for total DDT. These EDIs were only 0.075% of the acceptable daily intake (ADI) for lindane, 47.5% of ADI for heptachlor and heptachlor epoxide, 0.045% of ADI for total DDT, and 1.01% of ADI for aldrin and dieldrin. Therefore, consumption of the foods analyzed does not pose a risk to consumer health.

scholarly journals Dietary Exposure and Risk Assessment of Aflatoxin M1 for Children Aged 1 to 9 Years Old in Serbia

2021 ◽  
Author(s):  
Dragan R Milićević ◽  
Jelena Milešević ◽  
Mirjana Gurinovic ◽  
Saša Janković ◽  
Jasna Đinović ◽  
...  
Keyword(s):  
Age Groups ◽  
Daily Intake ◽  
Dietary Exposure ◽  
Food Samples ◽  
Aflatoxin M1 ◽  
Risk Characterization ◽  
Detection Rates ◽  
Risk Of Exposure ◽  
Group 1

The present study was conducted to estimate the exposure and risk characterization of the children population of Serbia to Aflatoxin M1 (AFM1) from milk and milk-based food. A total of 3404 samples comprising of milk and different milk-based food samples were collected from various regions of Serbia from 2017 to 2019. Evaluation of the AFM1 exposure was carried out using the deterministic method, whereas risk characterization was evaluated with the calculation of the Margin of Exposure (MOE) and the risk of Hepatocellular Carcinoma (HCC). Detection rates for AFM1 in milk and milk-based food samples ranged between 2% and 79%, with the highest incidence (79%) and mean level (22.34  0,018 ng kg-1) of AFM1 was detected in pasteurized and UHT milk. According to the three consumption estimates, the values of EDI were higher for toddlers as compared with children. Children aged 1–3 years had the highest risk of exposure to AFM1 in milk, with an estimated daily intake of 0.164 and 0.193 ng kg-1 bw day-1 using a lower bound (LB) and the upper bound (UB) exposure scenarios, respectively. Such difference could result from the higher consumption versus weight. Based on the EDI found in this study, the risk of AFM1 due to consumption of milk and milk-based food was low since MOE values obtained were 10000. In addition, the risk of HCC cases/year/105 individuals of different age groups showed that the value of HCC using potency estimates of 0.0017 (mean) was maximum (0.00034) in the age group 1–3 years which indicates no health risk for the evaluated groups. The present study revealed the importance of controlling and preventing AFM1 contamination in milk through continuous monitoring and regular inspection to reduce the risk of AFM1 exposure, especially in children.

scholarly journals Risk assessment of Portuguese population to multiple mycotoxins: the human biomonitoring approach

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
C Martins ◽  
A Vidal ◽  
S De Saeger ◽  
C Nunes ◽  
D Torres ◽  
...  
Keyword(s):  
Hazard Quotient ◽  
Daily Intake ◽  
Human Biomonitoring ◽  
Urine Samples ◽  
Internal Exposure ◽  
Risk Characterization ◽  
Food Contaminants ◽  
Portuguese Population ◽  
Individual Level ◽  
Paired Samples

Abstract Mycotoxins constitute a relevant group of food contaminants with several associated health outcomes such as estrogenic, immunotoxic, nephrotoxic and teratogenic effects. Although scarce data are available in Portugal, human biomonitoring studies have been globally developed to assess the exposure to mycotoxins at individual level. The present study concerned the analysis of mycotoxins in 24h urine and first-morning urine paired samples from 94 participants enrolled within the scope of the National Food, Nutrition, and Physical Activity Survey of the Portuguese General Population (2015-2016). Following a salt-assisted matrix extraction, urine samples were analyzed by liquid chromatography-mass spectrometry for the simultaneous determination of 37 urinary mycotoxins’ biomarkers and data obtained used to estimate the probable daily intake as well as the risk characterization applying the Hazard Quotient approach. Results revealed the exposure of Portuguese population to zearalenone, deoxynivalenol, ochratoxin A, alternariol, citrinin and fumonisin B1 through the quantification in 24h urine and first-morning urine paired samples. Risk characterization data revealed a potential concern to some reported mycotoxins since the reference intake values were exceeded by some of the considered participants. Alternariol was identified for the first time in urine samples from a European country; however, risk characterization was not performed due to lack of reference intake value. The present study contributed with reliable and evidence-based results, and confirmed that mycotoxins represent a burden and are part of the human exposome of the Portuguese population. Further studies are needed to shed a light on the determinants of exposure in order to contribute for the promotion of public health measures to reduce the mycotoxins’ exposure in Portugal. Key messages Portuguese population is exposed to mycotoxins, chemical food contaminants that may be harmful (carcinogenic, immunotoxic, mutagenic, teratogenic, hepatotoxic) for human health. Human biomonitoring studies provide realistic data on internal exposure at individual level, allowing a more accurate knowledge of the determinants of exposure to these contaminants.

scholarly journals Exposure assessment and risk characterization of n-nitrosodimethylamine (ndma) in the diet of children from 6 to 36 months in Hanoi, Vietnam

2020 ◽  
pp. 87-93
Author(s):  
Tran Cao Son ◽  
◽  
Nguyễn Thị Thanh Lam ◽  
Vu Ngoc Tu ◽  
Bui Quang Dong ◽  
...  
Keyword(s):  
Cancer Risk ◽  
Daily Intake ◽  
Exposure Dose ◽  
Food Samples ◽  
Tolerable Daily Intake ◽  
Risk Characterization ◽  
Suburban Areas ◽  
Food Consumption Survey ◽  
Consumption Survey

N-Nitrosodimethylamine (NDMA) is a highly hepatotoxic compound and classified as group 2A according to IARC, which is probably carcinogenic to humans. The habit of consumption of grilled meat-based foods may lead to a health risk, especially in children. In this study, a food consumption survey was conducted in 4 districts (2 in urban and 2 in suburban areas) in Hanoi, Vietnam. Food samples in the diet of children from 6 to 36 months was collected and tested for NDMA by GC-MS/MS method. Total exposure dose was calculated and compared to the proposed tolerable daily intake (TDI) to characterize the risk. Among the food tested, NDMA was detected in canned puree, grilled meat and sausage. The average contents of NDMA were 1.50 μg/kg, 1.18 μg/kg and 0.20 μg/kg in grilled meat, sausage and puree, respectively. The average total daily exposure dose of NDMA was 8.23 ng/kg bw/day in all studied group, which were within the upper recommended TDI (9.3 ng/kg bw/day). With a certain assumption, the cancer risk caused by exposure to NDMA were higher than the recommended value of WHO.

scholarly journals Exposure assessment and risk characterization of n-nitrosodimethylamine (ndma) in the diet of children from 6 to 36 months in Hanoi, Vietnam

2020 ◽  
pp. 87-93
Author(s):  
Tran Cao Son ◽  
◽  
Nguyen Thi Thanh Lam ◽  
Vu Ngoc Tu ◽  
Bui Quang Dong ◽  
...  
Keyword(s):  
Cancer Risk ◽  
Daily Intake ◽  
Exposure Dose ◽  
Food Samples ◽  
Tolerable Daily Intake ◽  
Risk Characterization ◽  
Suburban Areas ◽  
Food Consumption Survey ◽  
Consumption Survey

N-Nitrosodimethylamine (NDMA) is a highly hepatotoxic compound and classified as group 2A according to IARC, which is probably carcinogenic to humans. The habit of consumption of grilled meat-based foods may lead to a health risk, especially in children. In this study, a food consumption survey was conducted in 4 districts (2 in urban and 2 in suburban areas) in Hanoi, Vietnam. Food samples in the diet of children from 6 to 36 months was collected and tested for NDMA by GC-MS/MS method. Total exposure dose was calculated and compared to the proposed tolerable daily intake (TDI) to characterize the risk. Among the food tested, NDMA was detected in canned puree, grilled meat and sausage. The average contents of NDMA were 1.50 μg/kg, 1.18 μg/kg and 0.20 μg/kg in grilled meat, sausage and puree, respectively. The average total daily exposure dose of NDMA was 8.23 ng/kg bw/day in all studied group, which were within the upper recommended TDI (9.3 ng/kg bw/day). With a certain assumption, the cancer risk caused by exposure to NDMA were higher than the recommended value of WHO.

A Thorough Theoretical Exploration of Intriguing Characteristics of Cyclo[18]carbon: Geometry, Bonding Nature, Aromaticity, Weak Interaction, Reactivity, Excited States, Vibrations, Molecular Dynamics and Various Molecular Properties

2019 ◽  
Author(s):  
Tian Lu ◽  
Qinxue Chen ◽  
Zeyu Liu
Keyword(s):  
Molecular Dynamics ◽  
Excited States ◽  
Electronic Excitation ◽  
Ring Structure ◽  
Molecular Properties ◽  
Molecular Vibration ◽  
Full Characterization ◽  
Long Time ◽  
Almost All

Although cyclo[18]carbon has been theoretically and experimentally investigated since long time ago, only very recently it was prepared and directly observed by means of STM/AFM in condensed phase (Kaiser et al., <i>Science</i>, <b>365</b>, 1299 (2019)). The unique ring structure and dual 18-center π delocalization feature bring a variety of unusual characteristics and properties to the cyclo[18]carbon, which are quite worth to be explored. In this work, we present an extremely comprehensive and detailed investigation on almost all aspects of the cyclo[18]carbon, including (1) Geometric characteristics (2) Bonding nature (3) Electron delocalization and aromaticity (4) Intermolecular interaction (5) Reactivity (6) Electronic excitation and UV/Vis spectrum (7) Molecular vibration and IR/Raman spectrum (8) Molecular dynamics (9) Response to external field (10) Electron ionization, affinity and accompanied process (11) Various molecular properties. We believe that our full characterization of the cyclo[18]carbon will greatly deepen researchers' understanding of this system, and thereby help them to utilize it in practice and design its various valuable derivatives.

A Thorough Theoretical Exploration of Intriguing Characteristics of Cyclo[18]carbon: Geometry, Bonding Nature, Aromaticity, Weak Interaction, Reactivity, Excited States, Vibrations, Molecular Dynamics and Various Molecular Properties

2019 ◽  
Author(s):  
Tian Lu ◽  
Qinxue Chen ◽  
Zeyu Liu
Keyword(s):  
Molecular Dynamics ◽  
Excited States ◽  
Electronic Excitation ◽  
Ring Structure ◽  
Molecular Properties ◽  
Molecular Vibration ◽  
Full Characterization ◽  
Long Time ◽  
Almost All

Although cyclo[18]carbon has been theoretically and experimentally investigated since long time ago, only very recently it was prepared and directly observed by means of STM/AFM in condensed phase (Kaiser et al., <i>Science</i>, <b>365</b>, 1299 (2019)). The unique ring structure and dual 18-center π delocalization feature bring a variety of unusual characteristics and properties to the cyclo[18]carbon, which are quite worth to be explored. In this work, we present an extremely comprehensive and detailed investigation on almost all aspects of the cyclo[18]carbon, including (1) Geometric characteristics (2) Bonding nature (3) Electron delocalization and aromaticity (4) Intermolecular interaction (5) Reactivity (6) Electronic excitation and UV/Vis spectrum (7) Molecular vibration and IR/Raman spectrum (8) Molecular dynamics (9) Response to external field (10) Electron ionization, affinity and accompanied process (11) Various molecular properties. We believe that our full characterization of the cyclo[18]carbon will greatly deepen researchers' understanding of this system, and thereby help them to utilize it in practice and design its various valuable derivatives.

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